Glucuronidation of anti-HIV drug candidate bevirimat: Identification of human UDP-glucuronosyltransferases and species differences

Drug Metabolism and Disposition

Volumn 35, Issue 3, 2007, Pages 440-448

  Wen, Zhiming ^a   Martin, David E ^b   Bullock, Peter ^b   Lee, Kuo Hsiung ^a   Smith, Philip C ^a  

^a UNIVERSITY OF NORTH CAROLINA   (United States)

^b Panacos Pharmaceuticals   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

3 O (3,3 DIMETHYLSUCCINYL)BETULIC ACID; ANTI HUMAN IMMUNODEFICIENCY VIRUS AGENT; BEVIRIMAT; DIGLUCURONIDE; DRUG METABOLITE; GLUCURONIDE; GLUCURONOSYLTRANSFERASE; GLUCURONOSYLTRANSFERASE 1A4; GLUCURONOSYLTRANSFERASE 2B7; UNCLASSIFIED DRUG;

ARTICLE; CONTROLLED STUDY; DRUG METABOLISM; DRUG STRUCTURE; ENZYME KINETICS; GLUCURONIDATION; HUMAN; HUMAN CELL; IN VITRO STUDY; MICROSOME; MOLECULAR WEIGHT; PRIORITY JOURNAL;

ANIMALS; ANTI-HIV AGENTS; DOGS; GLUCURONIDES; GLUCURONOSYLTRANSFERASE; HUMANS; INTESTINES; LIVER; MICE; MICROSOMES; RATS; RECOMBINANT PROTEINS; SPECIES SPECIFICITY; SUCCINATES; TRITERPENES;

ANIMALIA; CANIS FAMILIARIS; HUMAN IMMUNODEFICIENCY VIRUS; MARMOSETS; RATTUS;

EID: 33847375101     PISSN: 00909556     EISSN: 1521009X     Source Type: Journal    
DOI: 10.1124/dmd.106.012815     Document Type: Article

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