Evaluation of bioadhesive polymers as delivery systems for nose to brain delivery: In vitro characterisation studies

Journal of Controlled Release

Volumn 118, Issue 2, 2007, Pages 225-234

  Charlton, S T ^a   Davis, S S ^a,b   Illum, L ^c  

^a UNIVERSITY OF NOTTINGHAM   (United Kingdom)

^b Cosmas Damian Ltd ^*  (United Kingdom)

^c IDentity   (United Kingdom)

Author keywords

Chitosan; Drug release; Drug transport; Nose to brain delivery; Pectin

Indexed keywords

ABSORPTION; BRAIN; CONTROLLED DRUG DELIVERY; NEUROLOGY; PATIENT TREATMENT; PHYSIOLOGICAL MODELS;

CHITOSAN; DRUG TRANSPORT; NOSE TO BRAIN DELIVERY; PECTIN;

BIOPOLYMERS;

CHITOSAN; PECTIN; POLYMER;

ANIMAL CELL; ARTICLE; CENTRAL NERVOUS SYSTEM DISEASE; CONTROLLED RELEASE FORMULATION; DRUG DELIVERY SYSTEM; DRUG FORMULATION; DRUG RELEASE; DRUG TRANSPORT; EPITHELIUM; GEL; IN VITRO STUDY; MOLECULAR WEIGHT; NONHUMAN; NOSE CAVITY; OLFACTORY EPITHELIUM; PRIORITY JOURNAL; VISCOSITY;

ADHESIVENESS; ADMINISTRATION, INTRANASAL; ANIMALS; BENZOFURANS; BRAIN; CELL LINE; CELL MEMBRANE PERMEABILITY; CENTRAL NERVOUS SYSTEM AGENTS; CHEMISTRY, PHARMACEUTICAL; CHITOSAN; DELAYED-ACTION PREPARATIONS; DIFFUSION; DOGS; DRUG CARRIERS; DRUG COMPOUNDING; EPITHELIAL CELLS; GELS; KINETICS; MANNITOL; METHYLATION; MODELS, CHEMICAL; MOLECULAR WEIGHT; NASAL MUCOSA; PECTINS; POLYMERS; PROPRANOLOL; SOLUBILITY; TISSUE ADHESIVES; VISCOSITY;

EID: 33847360911     PISSN: 01683659     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jconrel.2006.12.014     Document Type: Article

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