Microviscosity of hydroxypropylcellulose gels as a basis for prediction of drug diffusion rates

International Journal of Pharmaceutics

Volumn 180, Issue 1, 1999, Pages 91-103

  Alvarez Lorenzo, C ^a   Gomez Amoza J L ^a   Martinez Pacheco R ^a   Souto, C ^a   Concheiro, A ^a  

^a Universidade de Santiago de Compostela   (Spain)

Author keywords

Diffusion; Dynamic light scattering; Gels; Hydroxypropylcellulose; Theophylline; Viscosity

Indexed keywords

HYDROXYPROPYLCELLULOSE; KLUCEL MF; LATEX; MICROSPHERE; NISSO H; NISSO M; THEOPHYLLINE; TRITON X 100; UNCLASSIFIED DRUG;

ARTICLE; DIFFUSION COEFFICIENT; DRUG DIFFUSION; DRUG RELEASE; IN VITRO STUDY; MOLECULAR WEIGHT; PRIORITY JOURNAL; VISCOSITY;

CELLULOSE; DIFFUSION; GELS; THEOPHYLLINE; VISCOSITY;

EID: 0345059842     PISSN: 03785173     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0378-5173(98)00409-8     Document Type: Article

References (43)

1. Al-Khamis K.I., Davis S.S., Hadgraft J. Microviscosity and drug release from topical gel formulations. Pharm. Res. 3:1986;214-217.
2. Amstrong N.A., Gebre-Mariam T., James K.C., Kearney P. The influence of viscosity on the migration of chloramphenicol and 4-hydroxybenzoic acid through glycerogelatin gels. J. Pharm. Pharmacol. 39:1987;583-586.
3. Babar A., Pillai J., Plakogiannis F.M. Release and permeation studies of propranolol hydrochloride from hydrophilic polymeric matrices. Drug Dev. Ind. Pharm. 18:1992;1823-1830.
4. Bardet L., Alain M. Caractérisation physicochimique d'un haut polymer d'acide acrylique utilisé en pharmacie: II. Détermination de la masse moléculaire. Trav. Soc. Pharm. Montpellier. 35:1975;263-272.
5. Barry B.W., Brace A.C. Permeation of oestrone, oestradiol, oestriol and dexamethasone across cellulose acetate membrane. J. Pharm. Pharmacol. 29:1977;397-400.
6. Caramella C., Ferrari F., Bonferoni M.C., Ronchi M., Colombo P. Rheological properties and diffusion dissolution behaviour of hydrophilic polymers. Boll. Chim. Farm. 128:1989;298-302.
7. Cavallaro G., Giammona G., La Manna G., Palazzo S., Pitarresi G., Turco-Liveri V. Viscosimetric investigation of the interaction between sodim dodecylsulfate and a polymer drug carrier. Int. J. Pharm. 90:1993;195-201.
8. Demou J.S., Sidhom M.B., Plakogiannis F.M. Comparative in vitro diffusion studies for atenolol transdermal delivery system. Pharm. Acta Helv. 68:1994;215-219.
9. Duro R., Souto C., Gómez-Amoza J.L., Martínez-Pacheco R., Concheiro A. Cellulose ethers-polysorbate 80 interactions. Implications on the stability of pyrantel pamoate suspensions. Chem. Pharm. Bull. 46:1998;1421-1427.
10. El-Khordagui L.K. Hydrotrope-gelled starch: study of some physicochemical properties. Int. J. Pharm. 74:1991;25-32.
11. Gao P., Nixon P.R., Skoug J.W. Diffusion in HPMC gels. II. Prediction of drug release rates from hydrophilic matrix extended-release dosage forms. Pharm. Res. 12:1995;965-971.
12. Gebre-Mariam T., Armstrong N.A., James K.C., Evans J.C., Rowlands C.C. The use of electron spin resonance to measure microviscosity. J. Pharm. Pharmacol. 43:1991;510-512.
13. Gerharz B., Horst R. Phase behavior of the ternary system water/hydroxyethylcellulose/nonionic surfactant. Colloid Polym. Sci. 274:1996;439-445.
14. Higuchi W.I. Analysis of data on the medicament release from ointments. J. Pharm. Sci. 51:1962;802-804.
15. Hörner K.D., Töpper M., Ballauff M. Assessment of the depletion forces in mixtures of a polystyrene latex and hydroxyethylcellulose by turbidimetry. Langmuir. 13:1997;551-558.
16. Johnson P. Dilute solution behavior of polystyrene latex particles and their interaction with Triton X-100. Langmuir. 9:1993;2318-2325.
17. Joshi H.N., Wilson T.D. Calorimetric studies of dissolution of hydroxypropyl methylcellulose E5 (HPMC E5) in water. J. Pharm. Sci. 82:1992;1033-1038.
18. Kumar S., Himmelstein K.J. Modification of in situ gelling behaviour of carbopol solutions by hydroxypropyl methylcellulose. J. Pharm. Sci. 84:1995;344-348.
19. Lu G., Jun H.W. Diffusion studies of methotrexate in Carbopol and Poloxamer gels. Int. J. Pharm. 160:1998;1-9.
20. Martindale The Extrapharmacopoeia. 31th ed. 1998;1657-1665 The Pharmaceutical Press, London.
21. Mitchell K., Ford J.L., Armstrong D.J., Elliott P.N.C., Rostron C., Hogan J.E. The influence of additives on the cloud point, disintegration and dissolution of hydroxypropylmethylcellulose gels and matrix tablets. Int. J. Pharm. 66:1990;233-242.
22. Nelson K.G., Shah A.C. Mass transport in dissolution kinetics II. Convective diffusion to assess role of viscosity under conditions of gravitational flow. J. Pharm. Sci. 76:1987;910-913.
23. Persson B., Nilsson S., Sundelöf L.-O. On the characterization principles of some technically important water-soluble nonionic cellulose derivatives. Part II: surface tension and interaction with a surfactant. Carbohydr. Polym. 29:1996;119-127.
24. Phillies G.D.J., Clomenil D. Probe diffusion in polymer solutions under θ and good conditions. Macromolecules. 26:1993;167-170.
25. Phillies G.D.J., Lacroix M. Probe diffusion in hydroxypropylcellulose-water: radius and line-shape effects in the solution like regime. J. Phys. Chem. B. 101:1997;39-47.
26. Phillies G.D.J., Ullman G.S., Ullman K., Lin T.H. Phenomenological scaling laws for semidilute macromolecules solutions from light scattering by optical probe particles. J. Chem. Phys. 82:1985;5242-5245.
27. Qiao L., Easteal A.J. Mass transport in Triton X series nonionic surfactant solutions: a new approach to solute-solvent interactions. Colloid Polym. Sci. 274:1996;974-980.
28. Robitaille L., Turcotte N., Fortin S., Charlet G. Calorimetric study of aqueous solutions of hydroxypropylcellulose. Macromolecules. 24:1991;2413-2418.
29. Sarisuta N., Parrott E.L. Diffusivity and dissolution rate in polymeric solutions. Drug Dev. Ind. Pharm. 9:1983;861-875.
30. Shah A.C., Nelson K.G. Mass transport in dissolution kinetics II: Convective diffusion to assess role of viscosity under conditions of gravitational flow. J. Pharm. Sci. 76:1987;910-913.
31. Smidt J.H., Crommelin D.J.A. Viscosity measurement in aqueous polymer solutions by dynamic light scattering. Int. J. Pharm. 77:1991;261-264.
32. Smidt J.H., Offringa J.C.A., Crommelin D.J.A. Dissolution kinetics of theophylline in aqueous polymer solutions. Int. J. Pharm. 77:1991;255-257.
33. Stringer J.L., Peppas N.A. Diffusion of small molecular weight drugs in radiation-crosslinked poly(ethylene oxide) hydrogels. J. Control. Release. 42:1996;195-202.
34. Suh H., Jun H.W. Physicochemical and release studies of naproxen in poloxamer gels. Int. J. Pharm. 129:1996;13-20.
35. Sung K.C., Nixon P.R., Skoug J.W., Ju T.R., Gao P., Topp E.M., Patel M.V. Effect of formulation variables on drug and polymer release from HPMC-based matrix tablets. Int. J. Pharm. 142:1996;53-60.
36. Thuresson K., Lindman B. Effect of hydrophobic modification of a nonionic cellulose derivative on the interaction with surfactants. Phase behavior and association. J. Phys. Chem. B. 101:1997;6460-6468.
37. Tronac, Inc., 1992. Isoperibol Titration Calorimeter. Instruction and Service Manual. Tronac, Inc., Utah.
38. United States Pharmacopeia, XXII, National Formulary 17 (1990). The United States Pharmacopeial Convention Inc., Rockville, MD.
39. Vázquez M.J., Pérez-Marcos B., Gómez-Amoza J.L., Martínez-Pacheco R., Souto C., Concheiro A. Influence of technological variables on release of drugs from hydrophilic matrices. Drug Dev. Ind. Pharm. 18:1992;1355-1375.
40. Wan L.S.C., Heng P.W.S., Wong L.F. Relationship between polymer viscosity and drug release from a matrix system. Pharm. Res. 9:1992;1510-1514.
41. Wirick M.G., Waldman M.H. Solution properties of fractionated water-soluble hydroxypropyl cellulose. J. Appl. Polym. Sci. 14:1970;579-597.
42. Wu P.-C., Huang Y.-B., Fang J.-Y., Tsai Y.-H. Percutaneous absorption of captopril from hydrophilic cellulose derivatives through excised rabbit skin and human skin. Drug Dev. Ind. Pharm. 24:1998;179-182.
43. Yang T., Jamieson A.M. Diffusion of latex spheres through solutions of hydroxypropylcellulose in water. J. Colloid Interface Sci. 126:1988;220-230.