N-(5-fluoro-2-phenoxyphenyl)-N-(2-[131I]iodo-5-methoxybenzyl) acetamide: A potent iodinated radioligand for the peripheral-type benzodiazepine receptor in brain

Journal of Medicinal Chemistry

Volumn 50, Issue 4, 2007, Pages 848-855

  Zhang, Ming Rong ^a   Kumata, Katsushi ^a   Maeda, Jun ^a   Haradahira, Terushi ^a   Noguchi, Junko ^a   Suhara, Tetsuya ^a   Halldin, Christer ^b   Suzuki, Kazutoshi ^a  

^a NATIONAL INSTITUTE OF RADIOLOGICAL SCIENCES   (Japan)

^b KAROLINSKA INSTITUTE   (Sweden)

Author keywords

[No Author keywords available]

Indexed keywords

ACETAMIDE DERIVATIVE; ANISOLE DERIVATIVE; BENZODIAZEPINE RECEPTOR; CARBON 11; HYDROGEN PEROXIDE; IODINE 131; N (2,5 DIMETHOXYBENZYL) N (5 FLUORO 2 PHENOXYPHENYL)ACETAMIDE C 11; N (2,5 DIMETHOXYBENZYL) N (5 IODO 2 PHENOXYPHENYL)ACETAMIDE I 131; N (5 FLUORO 2 PHENOXYPHENYL) N (2 IODO 5 METHOXYBENZYL)ACETAMIDE I 131; OXIDIZING AGENT; RADIOLIGAND; SODIUM IODIDE; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; AUTORADIOGRAPHY; BRAIN; CHEMICAL REACTION; CONTROLLED STUDY; DRUG DESIGN; DRUG DISTRIBUTION; DRUG POTENCY; DRUG STRUCTURE; DRUG SYNTHESIS; EX VIVO STUDY; MALE; MOUSE; NONHUMAN; RADIOIODINATION; RAT; TISSUE DISTRIBUTION;

ACETAMIDES; ANILINE COMPOUNDS; ANIMALS; AUTORADIOGRAPHY; BRAIN; IODINE RADIOISOTOPES; LIGANDS; MALE; MICE; RATS; RATS, SPRAGUE-DAWLEY; RECEPTORS, GABA-A; TISSUE DISTRIBUTION;

EID: 33847348354     PISSN: 00222623     EISSN: None     Source Type: Journal    
DOI: 10.1021/jm061127n     Document Type: Article

References (36)

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