Mcl-1 depletion in apoptosis elicited by ionizing radiation in peritoneal resident macrophages of C3H mice

Journal of Immunology

Volumn 178, Issue 5, 2007, Pages 2923-2931

  Kubota, Yoshihisa ^a   Kinoshita, Keiji ^a   Suetomi, Katsutoshi ^a   Fujimori, Akira ^a   Takahashi, Sentaro ^a  

^a NATIONAL INSTITUTE OF RADIOLOGICAL SCIENCES   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

ANTISENSE OLIGONUCLEOTIDE; CASPASE INHIBITOR; CYTOCHROME C; INHIBITOR OF APOPTOSIS PROTEIN 1; PROTEASOME INHIBITOR; PROTEIN A1; PROTEIN BAX; PROTEIN BCL 2; PROTEIN BCL XL; PROTEIN MCL 1; SMALL INTERFERING RNA; UNCLASSIFIED DRUG;

ADOLESCENT; ANIMAL CELL; APOPTOSIS; ARTICLE; C3H MOUSE; C57BL 6 MOUSE; CONTROLLED STUDY; FEMALE; IONIZING RADIATION; MEMBRANE POTENTIAL; MITOCHONDRIAL MEMBRANE; MITOCHONDRIAL MEMBRANE POTENTIAL; MOUSE; NONHUMAN; PERITONEUM MACROPHAGE; PRIORITY JOURNAL; PROTEIN SYNTHESIS; RADIOSENSITIVITY; STRAIN DIFFERENCE;

EID: 33847347954     PISSN: 00221767     EISSN: None     Source Type: Journal    
DOI: 10.4049/jimmunol.178.5.2923     Document Type: Article

References (51)

1. Munn, D. H., A. C. Beall, D. Song, R. W. Wrenn, and D. C. Throckmorton. 1995. Activation-induced apoptosis in human macrophages: developmental regulation of a novel cell death pathway by macrophage colony-stimulating factor and interferon γ. J. Exp. Med. 181: 127-136.
2. Kiener, P. A., P. M. Davis, G. C. Starling, C. Mehlin, S. J. Klebanoff, J. A. Ledbetter, and W. C. Liles. 1997. Differential induction of apoptosis by Fas-Fas ligand interactions in human monocytes and macrophages. J. Exp. Med. 185: 1511-1516.
3. Kikuchi, H., R. Iizuka, S. Sugiyama, G. Gon, H. Mori, M. Arai, K. Mizumoto, and S. Imajoh-Ohmi. 1996. Monocytic differentiation modulates apoptotic response to cytotoxic anti-Fas antibody and tumor necrosis factor α in human monoblast U937 cells. J. Leukocyte Biol. 60: 778-783.
4. Perlman, H. L., J. Pagliari, C. Georganas, T. Mano, K. Walsh, and R. M. Pope. 1999. FLICE-inhibitory protein expression during macrophage differentiation confers resistance to fas-mediated apoptosis. J. Exp. Med. 190: 1679-1688.
5. Perkins, E. H., P. Nettesheim, and T. Morita. 1966. Radioresistance of the engulfing and degradative capacities of peritoneal phagocytes to kiloroentgen x-ray doses. J. Reticuloendothel. Soc. 3: 71-82.
6. Schmidtke, J. R., and F. J. Dixon. 1972. The functional capacity of x-irradiated macrophages. J. Immunol. 108: 1624-1630.
7. Mclennan, G., L. W. Oberley, and A. P. Autor. 1980. The role of oxygen-derived free radicals in radiation-induced damage and death of nondividing eucaryotic cells. Radiat. Res. 84: 122-132.
8. Lambert, L. E., and D. M. Paulnock. 1987. Modulation of macrophage function by γ-irradiation: acquisition of the primed cell intermediate stage of the macrophage tumoricidal activation pathway. J. Immunol. 139: 2834-2841.
9. Ibuki, Y., and R. Goto. 1997. Enhancement of NO production from resident peritoneal macrophages by in vitro γ-irradiation and its relationship to reactive oxygen intermediates. Free Radic. Biol. Med. 22: 1029-1035.
10. McKinney, L. C., E. M. Aquilla, D. Coffin, D. A. Wink, and Y. Vodovotz. 1998. Ionizing radiation potentiates the induction of nitric oxide synthase by IFN-γ and/or LPS in murine macrophage cell lines: role of TNF-α. J. Leukocyte Biol. 64: 459-466.
11. McKinney, L. C., E. M. Aquilla, D. Coffin, D. A. Wink, and Y. Vodovotz. 2000. Ionizing radiation potentiates the induction of nitric oxide synthase by interferon γ and/or lipopolysaccharide in murine macrophage cell lines: role of tumor necrosis factor α. Ann. NY Acad. Sci. 899: 61-68.
12. Ibuki, Y., S. Mizuno, and R. Goto. 2003. γ-Irradiation-induced DNA damage enhances NO production via NF-κB activation in RAW264.7 cells. Biochim. Biophys. Acta 1593: 159-167.
13. Thornton, S. C., B. J. Walsh, S. Bennett, J. M. Robbins, E. Foulcher, G. W. Morgan, R. Penny, and S. N. Breit. 1996. Both in vitro and in vivo irradiation are associated with induction of macrophage-derived fibroblast growth factors. Clin. Exp. Immunol. 103: 67-73.
14. Pons, I., G. Gras, S. Courberand, O. Benveniste, and D. Dormont. 1997. Consequences of γ-irradiation on inflammatory cytokine regulation in human monocytes/macrophages. Int. J. Radiat. Biol. 71: 157-166.
15. Hosoi, Y., H. Miyachi, Y. Matsumoto, A. Enomoto, K. Nakagawa, N. Suzuki, and T. Ono. 2001. Induction of interleukin-1β and interleukin-6 mRNA by low doses of ionizing radiation in macrophages. Int. J. Cancer 96: 270-276.
16. Kubota, Y., S. Takahashi, H. Sato, K. Suetomi, and S. Aizawa. 2004. Radiation-induced apoptosis in peritoneal resident macrophages of C3H mice. J. Radiat. Res. 45: 205-211.
17. Clarke, A. R., C. A. Purdie, D. J. Harrison, R. G. Morris, C. C. Bird, M. L. Hooper, and A. H. Wyllie. 1993. Thymocyte apoptosis induced by p53-dependent and independent pathways. Nature 362: 849-852.
18. Lowe, S. W., E. M. Schmitt, S. W. Smith, B. A. Osborne, and T. Jacks. 1993. p53 is required for radiation-induced apoptosis in mouse thymocytes. Nature 362: 847-849.
19. Enokido, Y., T. Araki, K. Tanaka, S. Aizawa, and H. Hatanaka. 1996. Involvement of p53 in DNA strand break-induced apoptosis in postmitotic CNS neurons. Eur. J. Neurosci. 8: 1812-1821.
20. Araki, T., Y. Enokido, N. Inamura, S. Aizawa, J. C. Reed, and H. Hatanaka. 1998. Changes in c-Jun but not Bcl-2 family proteins in p53-dependent apoptosis of mouse cerebellar granule neurons induced by DNA damaging agent bleomycin. Brain Res. 794: 239-247.
21. Konishi, A., S. Shimizu, J. Hirota, T. Takao, Y. Fan, Y. Matsuoka, L. Zhang, Y. Yoneda, Y. Fujii, A. I. Skoultchi, and Y. Tsujimoto. 2003. Involvement of histone H1.2 in apoptosis induced by DNA double-strand breaks. Cell 114: 673-688.
22. Herzog, K. H., M. J. Chong, M. Kapsetaki, J. I. Morgan, and P. J. Mckinnon. 1998. Requirement for Atm in ionizing radiation-induced cell death in the developing central nervous system. Science 280: 1089-1091.
23. 46, in response to ionizing radiation. J. Biol. Chem. 277: 12491-12494.
24. Bakkenist, C. J., and M. B. Kastan. 2003. DNA damage activates ATM through intermolecular autophosphorylation and dimer dissociation. Nature 421: 499-506.
25. Wang, S., M. Guo, H. Ouyang, X. Li, C. Cordon-Cardo, A. Kurimasa, D. J. Chen, Z. Fuks, C.-C. Ling, and G.-C. Li. 2000. The catalytic subunit of DNA-dependent protein kinase selectively regulates p53-dependent apoptosis but not cell-cycle arrest. Proc. Natl. Acad. Sci. USA 97: 1584-1588.
26. Mori, N., Y. Matsumoto, M. Okumoto, N. Suzuki, and J. Yamate. 2001. Variations in Prkdc encoding the catalytic subunit of DNA-dependent protein kinase (DNA-PKcs) and susceptibility to radiation-induced apoptosis and lymphomagenesis. Oncogene 20: 3609-3619.
27. Woo, R. A., M. T. Jack, Y. Xu, S. Burma, D. J. Chen, and P. W. Lee. 2002. DNA damage-induced apoptosis requires the DNA-dependent protein kinase, and is mediated by the latent population of p53. EMBO J. 21: 3000-3008.
28. Chan, D.-W., B.-P. Chen, S. Prithivirajsingh, A. Kurimasa, M. D. Story, J. Qin, and D. J. Chen. 2002. Autophosphorylation of the DNA-dependent protein kinase catalytic subunit is required for rejoining of DNA double-strand breaks. Genes Dev. 16: 2333-2338.
29. Merkle, D., P. Douglas, G. B. Moorhead, Z. Leonenko, Y. Yu, D. Cramb, D. P. Bazett-Jones, and S. P. Lees-Miller. 2002. The DNA-dependent protein kinase interacts with DNA to form a protein-DNA complex that is disrupted by phosphorylation. Biochemistry 41: 12706-12714.
30. Kubota, Y., S. Takahashi, H. Sato, and K. Suetomi. 2005. Radiation-induced apoptosis in peritoneal macrophages of C3H mice: selective involvement of superoxide anion, but not other reactive oxygen species. Int. J. Radiat. Biol. 81: 459-472.
31. Lizon, C., and P. Fritsch. 1999. Chemical toxicity of some actinides and lanthanides towards alveolar macrophages: an in vitro study. Int. J. Radiat. Biol. 75: 1459-1471.
32. Yang, Y., S. Fang, J. P. Jensen, A. M. Weissman, and J. D. Ashwell. 2000. Ubiquitin protein ligase activity of IAPs and their degradation in proteasomes in response to apoptotic stimuli. Science 288: 874-877.
33. Tonomura, N., K. McLaughlin, L. Grimm, R. A. Goldsby, and B. A. Osborne. 2003. Glucocorticoid-induced apoptosis of thymocytes: requirement of proteasome-dependent mitochondrial activity. J. Immunol. 170: 2469-2478.
34. Fribley, A., Q. Zeng, and C. Y. Wang. 2004. Proteasome inhibitor PS-341 induces apoptosis through induction of endoplasmic reticulum stress-reactive oxygen species in head and neck squamous cell carcinoma cells. Mol. Cell. Biol. 24: 9695-9704.
35. Kaufman, R. J. 2002. Orchestrating the unfolded protein response in health and disease. J. Clin. Invest. 110: 1389-1398.
36. Ron, D. 2002. Translational control in the endoplasmic reticulum stress response. J. Clin. Invest. 110: 1383-1388.
37. Wang, X. 2001. The expanding role of mitochondria in apoptosis. Genes Dev. 15: 2922-2933.
38. Adams, J. M., and S. Cory. 1998. The Bcl-2 protein family: arbiters of cell survival. Science 281: 1322-1326.
39. Cory, S., and J. M. Adams. 2002. The Bcl2 family: regulators of the cellular life-or-death switch. Nat. Rev. Cancer 2: 647-656.
40. Kozopas, K. M., T. Yang, H. L. Buchan, P. Zhou, and R. W. Craig. 1993. MCL1, a gene expressed in programmed myeloid cell differentiation, has sequence similarity to BCL2. Proc. Natl. Acad. Sci. USA 90: 3516-3520.
41. Zhou, P., L. Qian, K. M. Kozopas, and R. W. Craig. 1997. Mcl-1, a Bcl-2 family member, delays the death of hematopoietic cells under a variety of apoptosis-inducing conditions. Blood 89: 630-643.
42. Fukuchi, Y., M. Kizaki, K. Yamato, C. Kawamura, A. Umezawa, J. Hata, T. Nishihara, and Y. Ikeda. 2001. Mcl-1, an early-induction molecule, modulates activin A-induced apoptosis and differentiation of CML cells. Oncogene 20: 704-713.
43. Opferman, J. T., A. Letai, C. Beard, M. D. Sorcinelli, C. C. Ong, and S. J. Korsmeyer. 2003. Development and maintenance of B and T lymphocytes requires antiapoptotic MCL-1. Nature 426: 671-676.
44. Opferman, J. T., H. Iwasaki, C. C. Ong, H. Suh, S. Mizuno, K. Akashi, and S. J. Korsmeyer. 2005. Obligate role of anti-apoptotic MCL-1 in the survival of hematopoietic stem cells. Science 307: 1101-1104.
45. Zhang, B., I. Gojo, and R. G. Fenton. 2002. Myeloid cell factor-1 is a critical survival factor for multiple myeloma. Blood 99: 1885-1893.
46. Miyashita, T., S. Krajewski, M. Krajewska, H. G. Wang, H. K. Lin, D. A. Liebermann, B. Hoffman, and J. C. Reed. 1994. Tumor suppressor p53 is a regulator of bcl-2 and bax gene expression in vitro and in vivo. Oncogens 9: 1799-1805.
47. Findley, H. W., L. Gu, A. M. Yeager, and M. Zhou. 1997. Expression and regulation of Bcl-2, Bcl-xl, and Bax correlate with p53 status and sensitivity to apoptosis in childhood acute lymphoblastic leukemia. Blood 89: 2986-2993.
48. Zhan, Q., C. K. Bieszezad, I. Bae, A. J. Fornace, Jr., and R. W. Craig. 1997. Induction of BCL2 family member MCL1 as an early response to DNA damage. Oncogene 14: 1031-1039.
49. Nijhawan, D., M. Fang, E. Traer, Q. Zhong, W. Gao, F. Du, and X. Wang. 2003. Elimination of Mcl-1 is required for the initiation of apoptosis following ultraviolet irradiation. Genes Dev. 17: 1475-1486.
50. Bregman, D. B., R. Halaban, A. J. van Gool, K. A. Henning, E. C. Friedberg, and S. L. Warren. 1996. UV-induced ubiquitination of RNA polymerase II: a novel modification deficient in Cockayne syndrome cells. Proc. Natl. Acad. Sci. USA 93: 11586-11590.
51. Deng, J., H. P. Harding, B. Raught, A. C. Gingras, J. J. Berlanga, D. Scheuner, R. J. Kaufman, D. Ron, and N. Sonenberg. 2002. Activation of GCN2 in UV-irradiated cells inhibits translation. Curr. Biol. 12: 1279-1286.