Factors modulating the delivery and effect of enzymatic cargo conjugated with antibodies targeted to the pulmonary endothelium

Journal of Controlled Release

Volumn 118, Issue 2, 2007, Pages 235-244

  Shuvaev, Vladimir V ^a   Christofidou Solomidou, Melpo ^a   Scherpereel, Arnaud ^a,b   Simone, Eric ^e   Arguiri, Evguenia ^a   Tliba, Samira ^a   Pick, Jeremy ^a   Kennel, Stephen ^c   Albelda, Steven M ^a   Muzykantov, Vladimir R ^a,d  

^a UNIVERSITY OF PENNSYLVANIA   (United States)

^b INSTITUT PASTEUR DE LILLE   (France)

^c UNIVERSITY OF TENNESSEE GRADUATE SCHOOL OF MEDICINE   (United States)

^d Institute for Translational Medicine   (United States)

^e UNIVERSITY OF PENNSYLVANIA   (United States)

Author keywords

Drug delivery; Endothelium; Lungs; Oxidative stress; Thrombomodulin; Vascular immunotargeting

Indexed keywords

CELLS; CONTROLLED DRUG DELIVERY; DRUG THERAPY; MONOCLONAL ANTIBODIES; OPTIMIZATION; TISSUE;

CARGO DELIVERY; ENDOTHELIUM; LUNGS; OXIDATIVE STRESS; THROMBOMODULIN; VASCULAR IMMUNOTARGETING;

BIOMEDICAL ENGINEERING;

GLUCOSE OXIDASE; MONOCLONAL ANTIBODY;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; CROSS LINKING; DRUG DELIVERY SYSTEM; GENE TARGETING; GLUCOSE METABOLISM; HYPEROXIA; LUNG ENDOTHELIUM; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION;

ANIMALS; ANTIBODIES, MONOCLONAL; ANTIBODY AFFINITY; CHEMISTRY, PHARMACEUTICAL; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG CARRIERS; DRUG DELIVERY SYSTEMS; ENDOTHELIUM, VASCULAR; ENZYMES; GLUCOSE; GLUCOSE OXIDASE; HYDROGEN PEROXIDE; HYPEROXIA; INJECTIONS, INTRAVENOUS; LUNG; MICE; MICE, INBRED C57BL; MICROSPHERES; OXYGEN; POLYSTYRENES; THROMBOMODULIN; TIME FACTORS;

EID: 33847333388     PISSN: 01683659     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jconrel.2006.12.025     Document Type: Article

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