Probing the structural and molecular diversity of tumor vasculature

Trends in Molecular Medicine

Volumn 8, Issue 12, 2002, Pages 563-571

  Pasqualini, Renata ^a   Arap, Wadih ^a   McDonald, Donald M ^b  

^a UNIVERSITY OF TEXAS   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

DIPEPTIDASE; INTERLEUKIN 11 RECEPTOR; LIGAND; MICROSOMAL AMINOPEPTIDASE; RECEPTOR;

ARTHRITIS; ATHEROSCLEROSIS; BLOOD VESSEL; BRAIN BLOOD VESSEL; CELL ULTRASTRUCTURE; CONFOCAL MICROSCOPY; ENDOTHELIUM CELL; HUMAN; KIDNEY BLOOD VESSEL; LUNG BLOOD VESSEL; MOLECULAR BIOLOGY; MOLECULAR RECOGNITION; PANCREAS BLOOD FLOW; PHAGE DISPLAY; PROTEIN EXPRESSION; PROTEIN TARGETING; REVIEW; SKIN BLOOD VESSEL; TUMOR VASCULARIZATION;

EID: 0036892284     PISSN: 14714914     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1471-4914(02)02429-2     Document Type: Review

References (82)

1. Kolonin, M. et al. (2001) Molecular addresses in blood vessels as targets for therapy. Curr Opin. Chem. Biol. 5, 308-313
2. Trepel, M. et al. (2002) In vivo phage display and vascular heterogeneity: Implications for targeted medicine. Curr. Opin. Chem. Biol. 6, 399-404
3. Arap, W. et al. (2002) Steps toward mapping the human vasculature by phage display. Nat. Med. 8, 121-127
4. Pasqualini, R. and Arap, W. (2002) Translation of vascular proteomics into individualized therapeutics. In Pharmacogenomica (Licinio, J. and Wong, M-L., eds), pp. 525-530, Wiley-VCH Verlag GmbH
5. Crone, C. and Levitt, D.G. (1984) Capillary permeability to small solutes. In Microcirculation, Part 1 (Vol. 4) (Renkin, E.M. and Michel, C.C., eds), pp. 411-466, American Physiological Society
6. Taylor, A.E. and Granger, D.N. (1984) Exchange of macromolecules across the microcirculation. In Microcirculation, Part 1 (Vol. 4) (Renkin, E.M. and Michel, C.C., eds), pp. 467-520, American Physiological Society
7. Bennett, H.S. et al. (1959) Morphological classifications of vertebrate blood capillaries. Am. J. Physiol. 196, 381-390
8. Majno, G. (1965) Ultrastructure of the vascular membrane. In Microcirculation (Vol. 3) (Hamilton, W.F. and Dow, P., eds), pp. 2293-2375, American Physiological Society
9. Majno, G. and Joris, I. (1978) Endothelium 1977: A review. Adv. Exp. Med. Biol. 104, 169-225
10. Simionescu, M. and Simionescu, N. (1984) Ultrastructure of the microvascular wall: Functional correlations. In Microcirculation, Part 1 (Vol. 4) (Renkin, E.M. and Michel, C.C., eds). pp. 41-101, American Physiological Society
11. Rhodin, J.A.G. (1974) Histology: A Text and Atlas, Oxford University Press
12. Majno, G. and Joris, I. (1996) Cells, Tissue, and Disease. Principles of General Pathology, Blackwell Science
13. Burkitt, H.G. et al. (1993) Wheater's Functional Histology. A Text and Colour Atlas, Churchhill Livingstone, London, UK
14. Reese, T.S. and Karnovsky, M.J. (1967) Fine structural localization of a blood-brain barrier to exogenous peroxidase. J. Cell Biol. 34, 207-217
15. Brightman, M.W. and Reese, T.S. (1969) Junctions between intimately apposed cell membranes in the vertebrate brain. J. Cell Biol. 40, 648-677
16. Fawcett, D.W. et al. (1970) Electron microscopic observations on the structural components of the blood-testis barrier. J. Reprod. Fertil. 10 (Suppl.), 105-122
17. Dym, M. and Fawcett, D.W. (1970) The blood-testis barrier in the rat and the physiological compartmentation of the seminiferous epithelium. Biol. Reprod. 3, 308-326
18. Schneeberger, E.E. (1974) Glomerular permeability to protein molecules - Its possible structural basis. Nephron 13, 7-21
19. Renkin, E.M. and Robinson, R.R. (1974) Glomerular filtration. N. Engl. J. Med. 290, 785-792
20. Anderson, N.D. et al. (1976) Specialized structure and metabolic activities of high endothelial venules in rat lymphatic tissues. Immunology 31, 455-473
21. Butcher, E.C. et al. (1980) Organ specificity of lymphocyte migration: Mediation by highly selective lymphocyte interaction with organ-specific determinants on high endothelial venules. Eur. J. Immunol. 10, 556-561
22. Muto, M. (1976)A scanning and transmission electron microscopic study on rat bone marrow sinuses and transmural migration of blood cells. Arch. Histol. Jpn. 39, 51-66
23. Goresky, C.A. and Groom, A.C. (1984) Microcirculatory events in the liver and spleen. In Microcirculation, Part 2 (Vol. 4) (Renkin, E.M. and Michel, C.C., eds), pp. 689-780, American Physiological Society
24. Fenstermacher, J.D. and Rapoport, S.I. (1984) Blood-brain barrier. In Microcirculation, Part 2 (Vol. 4) (Renkin, E.M. and Michel, C.C., eds), pp. 969-1000, American Physiological Society
25. Verkman, A.S. (1998) Role of aquaporin water channels in kidney and lung. Am. J. Med. Sci. 316, 310-320
26. Verkman, A.S. et al. (2000) Aquaporin water channels and lung physiology. Am. J. Physiol. Lung Cell. Mol. Physiol. 278, L867-L879
27. King, L.S. et al. (2002) Decreased pulmonary vascular permeability in aquaporin-1-null humans. Proc. Natl. Acad. Sci. U. S. A. 99, 1059-1063
28. Moore, M.G. et al. (1984) Production of monoclonal antibodies to rat lung angiotensin-converting enzyme. Clin. Immunol. Immunopathol. 33, 301-312
29. Danilov, S.M. et al. (1991) Lung is the target organ for a monoclonal antibody to angiotensin-converting enzyme. Lab. Invest. 64, 118-124
30. 3H uptake by pulmonary endothelial cells. J. Cell Biol. 54, 456-467
31. Gillis, C.N. and Pitt, B.R. (1982) The fate of circulating amines within the pulmonary circulation. Annu. Rev. Physiol. 44, 269-281
32. Paczkowski, N.J. et al. (1996) Conclusive evidence for distinct transporters for 5-hydroxytryptamine and noradrenaline in pulmonary endothelial cells of the rat. Naunyn Schmiedebergs Arch. Pharmacol. 353, 423-430
33. Wyne, K.L. et al. (1996) Expression of the VLDL receptor in endothelial cells. Arterioscler. Thromb. Vasc. Biol. 16, 407-415
34. Soda, R. and Tavassoli, M. (1984) Liver endothelium and not hepatocytes or Kupffer cells have transferrin receptors. Blood 63, 270-276
35. Lovdal, T. et al. (2000) Fc receptor mediated endocytosis of small soluble immunoglobulin G immune complexes in Kupffer and endothelial cells from rat liver. J. Cell Sci. 113, 3255-3266
36. Muro, H. et al. (1988) Localization of Fc receptors on liver sinusoidal endothelium. A histological study by electron microscopy. Acta Pathol. Jpn. 38, 291-301
37. Jansen, R.W. et al. (1991) Formaldehyde treated albumin contains monomeric and polymeric forms that are differently cleared by endothelial and Kupffer cells of the liver: Evidence for scavenger receptor heterogeneity. Biochem. Biophys. Res. Commun. 180, 23-32
38. Esbach, S. et al. (1994) Morphological characterization of scavenger receptor-mediated processing of modified lipoproteins by rat liver endothelial cells. Exp. Cell Res. 210, 62-70
39. Krogh, A. (1929) The Anatomy and Physiology of Capillaries, Yale University Press
40. Bowden, J.J. et al. (1994) Direct observation of substance P-induced internalization of neurokinin 1 (NK1) receptors at sites of inflammation. Proc. Natl. Acad. Sci. U. S. A. 91, 8964-8968
41. Thurston, G. et al. (1996) Permeability-related changes revealed at endothelial cell borders in inflamed venules by lectin binding. Am. J. Physiol. 271, H2547-H2562
42. Ley, K. (1994) Histamine can induce leukocyte rollingin rat mesenteric venules. Am. J. Physiol. 267, H1017-H1023
43. Armstead, VE. et al. (1997) P-selectin is up-regulated in vital organs during murine traumatic shock. FASEB J. 11, 1271-1279
44. Thurston, G. et al. (2000) Determinants of endothelial cell phenotype in venules. Microcirculation 7, 67-80
45. Cines, D.B. et al. (1998) Endothelial cells in physiology and in the pathophysiology of vascular disorders. Blood 91, 3527-3561
46. McLean, J.W. et al. (1997) Organ-specific endothelial cell uptake of cationic liposome-DNA complexes in mice. Am. J. Physiol. 273, H387-H404
47. McDonald, D.M. and Foss, A.J. (2000) Endothelial cells of tumor vessels: Abnormal but not absent. Cancer Metastasis Rev. 19, 109-120
48. Jain, R.K. (1987) Transport of molecules across tumor vasculature. Cancer Metastasis Rev. 6, 559-593
49. Peterson, H-I. (1979) Vascular and extravascular spaces in tumors: Tumor vascular permeability. In Tumor Blood Circulation: Angiogenesis, Vascular Morphology and Blood Flow of Experimental and Human Tumors (Peterson, H-I., ed.), pp. 77-85, CRC Press, Boca Raton, FL, USA
50. Dvorak, H.F. et al. (1988) Identification and characterization of the blood vessels of solid tumors that are leaky to circulating macromolecules. Am. J. Pathol. 133, 95-109
51. Daldrup, H. et al. (1998) Correlation of dynamic contrast-enhanced MR imaging with histologic tumor grade: Comparison of macromolecular and small-molecular contrast media. Am. J. Roentgenol. 171, 941-949
52. Hobbs, S.K. et al. (1998) Regulation of transport pathways in tumor vessels: Role of tumor type and microenvironment. Proc. Natl. Acad. Sci. U. S. A. 95, 4607-4612
53. Maniotis, A.J. et al. (1999) Vascular channel formation by human melanoma cells in vivo and in vitro: Vasculogenic mimicry. Am. J. Pathol. 155, 739-752
54. Shirakawa, K. et al. (2002) Vasculogenic mimicry and pseudo-comedo formation in breast cancer. Int. J. Cancer 99, 821-828
55. Shirakawa, K. et al. (2002) Hemodynamics in vasculogenic mimicry and angiogenesis of inflammatory breast cancer xenograft. Cancer Res. 62, 560-566
56. Clarijs, R. et al. (2002) Presence of a fluid-conducting meshwork in xenografted cutaneous and primary human uveal melanoma. Invest. Ophthalmol. Vis. Sci. 43, 912-918
57. McDonald, D.M. et al. (2000) Vasculogenic mimicry: How convincing, how novel, and how significant? Am. J. Pathol. 156, 383-388
58. Hendrix, M.J. et al. (2001) Expression and functional significance of VE-cadherin in aggressive human melanoma cells: Role in vasculogenic mimicry. Proc. Natl. Acad. Sci. U. S. A. 98, 8018-8023
59. Chang, Y.S. et al. (2000) Mosaic blood vessels in tumors: Frequency of cancer cells in contact with flowing blood. Proc. Natl. Acad. Sci. U. S. A. 97, 14608-14613
60. Hashizume, H. et al. (2000) Openings between defective endothelial cells explain tumor vessel leakiness. Am. J. Pathol. 156, 1363-1380
61. Morikawa, S. et al. (2002) Abnormalities in pericytes on blood vessels and endothelial sprouts in tumors. Am. J. Pathol. 160, 985-1000
62. Vracko, R. (1974) Basal lamina scaffold anatomy and significance for maintenance of orderly tissue structure. Am. J. Pathol. 77, 314-346
63. Thurston, G. et al. (1998) Cationic liposomes target angiogenic endothelial cells in tumors and chronic inflammation in mice. J. Clin. Invest. 101, 1401-1413
64. Smith, G.P. (1985) Filamentous fusion phage: Novel expression vectors that display cloned antigens on the virion surface. Science 228, 1315-1317
65. Smith, G.P. and Scott, J.K. (1993) Libraries of peptides and proteins displayed on filamentous phage. Methods Enzymol. 217, 228-257
66. Pasqualini, R. et al. (2000) In vivo selection of phage-display libraries. In Phage Display: A Laboratory Manual (Barbas, C.F., III et al., eds), pp. 22-24, Cold Spring Harbor Laboratory Press
67. Pasqualini, R. and Ruoslahti, E. (1996) Organ targeting in vivo using phage display peptide libraries. Nature 380, 364-366
68. Arap, W. et al. (1998) Chemotherapy targeted to tumor vasculature. Curr Opin. Oncol. 10, 560-565
69. Rajotte, D. et al. (1998) Molecular heterogeneity of the vascular endothelium revealed by in vivo phage display. J. Clin. Invest. 102, 430-437
70. Rajotte, D. and Ruoslahti, E. (1999) Membrane dipeptidase is the receptor for a lung-targeting peptide identified by in vivo phage display. J. Biol. Chem. 274, 11593-11598
71. Ellerby, H.M. et al. (1999) Anti-cancer activity of targeted pro-apoptotic peptides. Nat. Med. 5, 1032-1038
72. Pasqualini, R. et al. (2000) Aminopeptidase N is a receptor for tumor-homing peptides and a target for inhibiting angiogenesis. Cancer Res. 60, 722-727
73. Dellabona, P. et al. (1999) Vascular attack and immunotherapy: A 'two hits' approach to improve biological treatment of cancer. Gene Ther 6, 153-154
74. Gasparri, A. et al. (1999) Tumor pretargeting with avidin improves the therapeutic index of biotinylated tumor necrosis factor alpha in mouse models. Cancer Res. 59, 2917-2923
75. Burg, M.A. et al. (1999) NG2 proteoglycan-binding peptides target tumor neovasculature. Cancer Res. 59, 2869-2874
76. Koivunen, E. et al. (1999) Identification of receptor ligands with phage display peptide libraries. J. Nucl. Med. 40, 883-888
77. Koivunen, E. et al. (1999) Tumor targeting with a selective gelatinase inhibitor. Nat. Biotechnol. 17, 768-774
78. Arap, W. et al. (1998) Cancer treatment by targeted drug delivery to tumor vasculature in a mouse model. Science 279, 377-380
79. Curnis, F. et al. (2000) Enhancement of tumor necrosis factor α antitumor immunotherapeutic properties by targeted delivery to aminopeptidase N (CD13). Nat. Biotechnol. 18, 1185-1190
80. Folkman, J. (1997) Addressing tumor blood vessels. Nat. Biotechnol. 15, 510
81. Bussolino, F. et al. (1997) Molecular mechanisms of blood vessel formation. Trends Biochem. Sci. 22, 251-256
82. 2 integrin-mediated leukocyte cell adhesion by leucine-leucine-glycine motif-containing peptides. J. Cell Biol. 153, 905-916