-
1
-
-
0031672857
-
The genetic and molecular mechanisms of motor neuron disease
-
Wong, P. C.,.Rothstein, J. D. and Price, D. L. (1998) The genetic and molecular mechanisms of motor neuron disease. Curr Opin Neurobiol, 8, pp. 791-799.
-
(1998)
Curr Opin Neurobiol
, vol.8
, pp. 791-799
-
-
Wong, P.C.1
Rothstein, J.D.2
Price, D.L.3
-
2
-
-
0027401203
-
Mutations in Cu/Zn superoxide dismutase gene are associated with familial amyotrophic lateral sclerosis
-
Rosen, D. R.,.Siddique, T.,.Patterson, D.,.Figlewicz, D. A.,.Sapp, P. and Hentati, A. (1993) Mutations in Cu/Zn superoxide dismutase gene are associated with familial amyotrophic lateral sclerosis. Nature, 362, pp. 59-62.
-
(1993)
Nature
, vol.362
, pp. 59-62
-
-
Rosen, D.R.1
Siddique, T.2
Patterson, D.3
Figlewicz, D.A.4
Sapp, P.5
Hentati, A.6
-
3
-
-
0029053881
-
An adverse property of a familial ALS-linked SOD1 mutation causes motor neuron disease characterized by vacuolar degeneration of mitochondria
-
Wong, P. C.,.Pardo, C. A.,.Borchelt, D. R.,.Lee, M. K.,.Copeland, N. G. and Jenkins, N. A. (1995) An adverse property of a familial ALS-linked SOD1 mutation causes motor neuron disease characterized by vacuolar degeneration of mitochondria. Neuron, 14, pp. 1105-1116.
-
(1995)
Neuron
, vol.14
, pp. 1105-1116
-
-
Wong, P.C.1
Pardo, C.A.2
Borchelt, D.R.3
Lee, M.K.4
Copeland, N.G.5
Jenkins, N.A.6
-
4
-
-
0031837890
-
The involvement of the Golgi apparatus in the pathogenesis of amyotrophic lateral sclerosis, Alzheimer's disease, and ricin intoxication
-
Gonatas, N. K.,.Gonatas, J. O. and Stieber, A. (1998) The involvement of the Golgi apparatus in the pathogenesis of amyotrophic lateral sclerosis, Alzheimer's disease, and ricin intoxication. Histochem Cell Biol, 109, pp. 591-600.
-
(1998)
Histochem Cell Biol
, vol.109
, pp. 591-600
-
-
Gonatas, N.K.1
Gonatas, J.O.2
Stieber, A.3
-
5
-
-
0029890685
-
The Golgi apparatus of spinal cord motor neurons in transgenic mice expressing mutant Cu/Zn superoxide dismutase becomes fragmented in early, preclinical stages of the disease
-
Mourelatos, Z.,.Gonatas, N. K.,.Stieber, A.,.Gurney, M. E. and Canto, M. C. Dal (1996) The Golgi apparatus of spinal cord motor neurons in transgenic mice expressing mutant Cu/Zn superoxide dismutase becomes fragmented in early, preclinical stages of the disease. Proc Natl Acad Sci USA, 93, pp. 5472-5477.
-
(1996)
Proc Natl Acad Sci USA
, vol.93
, pp. 5472-5477
-
-
Mourelatos, Z.1
Gonatas, N.K.2
Stieber, A.3
Gurney, M.E.4
Canto, M.C.5
Dal Canto, M.C.6
-
6
-
-
0030019414
-
Ultrastructural study of synapses in the anterior horn neurons of patients with amyotrophic lateral sclerosis
-
Sasaki, S. and Iwata, M. (1996) Ultrastructural study of synapses in the anterior horn neurons of patients with amyotrophic lateral sclerosis. Neurosci Lett, 204, pp. 53-56.
-
(1996)
Neurosci Lett
, vol.204
, pp. 53-56
-
-
Sasaki, S.1
Iwata, M.2
-
7
-
-
0031915174
-
Cytochrome c oxidase subunit I microdeletion in a patient with motor neuron disease
-
Comi, G. P.,.Bordoni, A.,.Salani, S.,.Franceschina, L.,.Sciacco, M. and Prelle, A. (1998) Cytochrome c oxidase subunit I microdeletion in a patient with motor neuron disease. Ann Neurol, 43, pp. 110-116.
-
(1998)
Ann Neurol
, vol.43
, pp. 110-116
-
-
Comi, G.P.1
Bordoni, A.2
Salani, S.3
Franceschina, L.4
Sciacco, M.5
Prelle, A.6
-
8
-
-
0032840228
-
Aberrant copper chemistry as a major mediator of oxidative stress in a human cellular model of amyotrophic lateral sclerosis
-
Gabbianelli, R.,.Ferri, A.,.Rotilio, G. and Carri, M. T. (1999) Aberrant copper chemistry as a major mediator of oxidative stress in a human cellular model of amyotrophic lateral sclerosis. J Neurochem, 73, pp. 1175-1180.
-
(1999)
J Neurochem
, vol.73
, pp. 1175-1180
-
-
Gabbianelli, R.1
Ferri, A.2
Rotilio, G.3
Carri, M.T.4
-
9
-
-
0023821329
-
Ca2+ release from mitochondria induced by pro-oxidants
-
Richter, C. and Frei, B. (1988) Ca2+ release from mitochondria induced by pro-oxidants. Free Radic Biol Med, 4, pp. 365-375.
-
(1988)
Free Radic Biol Med
, vol.4
, pp. 365-375
-
-
Richter, C.1
Frei, B.2
-
10
-
-
0024996681
-
The oxidative inactivation of mitochondrial electron transport chain components and ATPase
-
Zhang, Y.,.Marcillat, O.,.Giulivi, C.,.Ernster, L. and Davies, K. J. (1990) The oxidative inactivation of mitochondrial electron transport chain components and ATPase. J Biol Chem, 265, pp. 16330-16336.
-
(1990)
J Biol Chem
, vol.265
, pp. 16330-16336
-
-
Zhang, Y.1
Marcillat, O.2
Giulivi, C.3
Ernster, L.4
Davies, K.J.5
-
11
-
-
0036176613
-
Mitochondrial involvement in amyotrophic lateral sclerosis
-
Menzies, F. M.,.Ince, P. G. and Shaw, P. J. (2002) Mitochondrial involvement in amyotrophic lateral sclerosis. Neurochem Int, 40, pp. 543-551.
-
(2002)
Neurochem Int
, vol.40
, pp. 543-551
-
-
Menzies, F.M.1
Ince, P.G.2
Shaw, P.J.3
-
12
-
-
0028125281
-
Transgenic-mouse model of amyotrophic lateral sclerosis
-
Gurney, M. E. (1994) Transgenic-mouse model of amyotrophic lateral sclerosis. N Engl J Med, 331, pp. 1721-1722.
-
(1994)
N Engl J Med
, vol.331
, pp. 1721-1722
-
-
Gurney, M.E.1
-
13
-
-
0032079517
-
Massive mitochondrial degeneration in motor neurons triggers the onset of amyotrophic lateral sclerosis in mice expressing a mutant SOD1
-
Kong, J. and Xu, Z. (1998) Massive mitochondrial degeneration in motor neurons triggers the onset of amyotrophic lateral sclerosis in mice expressing a mutant SOD1. J Neurosci, 18, pp. 3241-3250.
-
(1998)
J Neurosci
, vol.18
, pp. 3241-3250
-
-
Kong, J.1
Xu, Z.2
-
14
-
-
0032745071
-
Mitochondrial enzyme activity in amyotrophic lateral sclerosis: Implications for the role of mitochondria in neuronal cell death
-
Borthwick, G. M.,.Johnson, M. A.,.Ince, P. G.,.Shaw, P. J. and Turnbull, D. M. (1999) Mitochondrial enzyme activity in amyotrophic lateral sclerosis: Implications for the role of mitochondria in neuronal cell death. Ann Neurol, 46, pp. 787-790.
-
(1999)
Ann Neurol
, vol.46
, pp. 787-790
-
-
Borthwick, G.M.1
Johnson, M.A.2
Ince, P.G.3
Shaw, P.J.4
Turnbull, D.M.5
-
15
-
-
0033974440
-
Chronic mitochondrial inhibition induces selective motor neuron death in vitro: A new model for amyotrophic lateral sclerosis
-
Kaal, E. C.,.Vlug, A. S.,.Versleijen, M. W.,.Kuilman, M.,.Joosten, E. A. and Bar, P. R. (2000) Chronic mitochondrial inhibition induces selective motor neuron death in vitro: A new model for amyotrophic lateral sclerosis. J Neurochem, 74, pp. 1158-1165.
-
(2000)
J Neurochem
, vol.74
, pp. 1158-1165
-
-
Kaal, E.C.1
Vlug, A.S.2
Versleijen, M.W.3
Kuilman, M.4
Joosten, E.A.5
Bar, P.R.6
-
16
-
-
0033051815
-
Neuroprotective effects of creatine in a transgenic animal model of amyotrophic lateral sclerosis
-
Klivenyi, P.,.Ferrante, R. J.,.Matthews, R. T.,.Bogdanov, M. B.,.Klein, A. M. and Andreassen, O. A. (1999) Neuroprotective effects of creatine in a transgenic animal model of amyotrophic lateral sclerosis. Nat Med, 5, pp. 347-350.
-
(1999)
Nat Med
, vol.5
, pp. 347-350
-
-
Klivenyi, P.1
Ferrante, R.J.2
Matthews, R.T.3
Bogdanov, M.B.4
Klein, A.M.5
Andreassen, O.A.6
-
17
-
-
0023270442
-
Hepatic ultrastructural changes and liver dysfunction in amyotrophic lateral sclerosis
-
Nakano, Y.,.Hirayama, K. and Terao, K. (1987) Hepatic ultrastructural changes and liver dysfunction in amyotrophic lateral sclerosis. Arch Neurol, 44, pp. 103-106.
-
(1987)
Arch Neurol
, vol.44
, pp. 103-106
-
-
Nakano, Y.1
Hirayama, K.2
Terao, K.3
-
18
-
-
0029809528
-
Amyotrophic lateral sclerosis: Oxidative energy metabolism and calcium homeostasis in peripheral blood lymphocytes
-
Curti, D.,.Malaspina, A.,.Facchetti, G.,.Camana, C.,.Mazzini, L. and Tosca, P. (1996) Amyotrophic lateral sclerosis: Oxidative energy metabolism and calcium homeostasis in peripheral blood lymphocytes. Neurology, 47, pp. 1060-1064.
-
(1996)
Neurology
, vol.47
, pp. 1060-1064
-
-
Curti, D.1
Malaspina, A.2
Facchetti, G.3
Camana, C.4
Mazzini, L.5
Tosca, P.6
-
19
-
-
0013911740
-
Ultrastructure of atrophic muscle in amyotrophic lateral sclerosis
-
Afifi, A. K.,.Aleu, F. P.,.Goodgold, J. and MacKay, B. (1966) Ultrastructure of atrophic muscle in amyotrophic lateral sclerosis. Neurology, 16, pp. 475-481.
-
(1966)
Neurology
, vol.16
, pp. 475-481
-
-
Afifi, A.K.1
Aleu, F.P.2
Goodgold, J.3
MacKay, B.4
-
20
-
-
0033917463
-
Mitochondrial DNA abnormalities in skeletal muscle of patients with sporadic amyotrophic lateral sclerosis
-
Vielhaber, S.,.Kunz, D.,.Winkler, K.,.Wiedemann, F. R.,.Kirches, E. and Feistner, H. (2000) Mitochondrial DNA abnormalities in skeletal muscle of patients with sporadic amyotrophic lateral sclerosis. Brain, 123, pp. 1339-1348.
-
(2000)
Brain
, vol.123
, pp. 1339-1348
-
-
Vielhaber, S.1
Kunz, D.2
Winkler, K.3
Wiedemann, F.R.4
Kirches, E.5
Feistner, H.6
-
21
-
-
0032716335
-
Visualization of defective mitochondrial function in skeletal muscle fibres of patients with sporadic amyotrophic lateral sclerosis
-
Vielhaber, S.,.Winkler, K.,.Kirches, E.,.Kunz, D.,.Buchner, M. and Feistner, H. (1999) Visualization of defective mitochondrial function in skeletal muscle fibres of patients with sporadic amyotrophic lateral sclerosis. J Neurol Sci, 169, pp. 133-139.
-
(1999)
J Neurol Sci
, vol.169
, pp. 133-139
-
-
Vielhaber, S.1
Winkler, K.2
Kirches, E.3
Kunz, D.4
Buchner, M.5
Feistner, H.6
-
22
-
-
0032539791
-
Impairment of mitochondrial function in skeletal muscle of patients with amyotrophic lateral sclerosis
-
Wiedemann, F. R.,.Winkler, K.,.Kuznetsov, A. V.,.Bartels, C.,.Vielhaber, S. and Feistner, H. (1998) Impairment of mitochondrial function in skeletal muscle of patients with amyotrophic lateral sclerosis. J Neurol Sci, 156, pp. 65-72.
-
(1998)
J Neurol Sci
, vol.156
, pp. 65-72
-
-
Wiedemann, F.R.1
Winkler, K.2
Kuznetsov, A.V.3
Bartels, C.4
Vielhaber, S.5
Feistner, H.6
-
23
-
-
23444445882
-
Mitochondrial changes in skeletal muscle in amyotrophic lateral sclerosis and other neurogenic atrophies
-
Krasnianski, A.,.Deschauer, M.,.Neudecker, S.,.Gellerich, F. N.,.Muller, T. and Schoser, B. G. (2005) Mitochondrial changes in skeletal muscle in amyotrophic lateral sclerosis and other neurogenic atrophies. Brain, 128, pp. 1870-1876.
-
(2005)
Brain
, vol.128
, pp. 1870-1876
-
-
Krasnianski, A.1
Deschauer, M.2
Neudecker, S.3
Gellerich, F.N.4
Muller, T.5
Schoser, B.G.6
-
24
-
-
33847308349
-
Airlie House guidelines. Therapeutic trials in amyotrophic lateral sclerosis. Airlie House 'Therapeutic Trials in ALS'
-
World Federation of Neurology Research Group on Neuromuscular Diseases Subcommittee on Motor Neuron Disease Workshop Contributors
-
World Federation of Neurology Research Group on Neuromuscular Diseases Subcommittee on Motor Neuron Disease (1995) Airlie House guidelines. Therapeutic trials in amyotrophic lateral sclerosis. Airlie House 'Therapeutic Trials in ALS' Workshop Contributors. J Neurol Sci, 129
-
(1995)
J Neurol Sci
, vol.129
-
-
-
25
-
-
0033924202
-
Creatine therapy in myophosphorylase deficiency (McArdle disease): A placebo-controlled crossover trial
-
Vorgerd, M.,.Grehl, T.,.Jager, M.,.Müller, K.,.Freitag, G. and Patzold, T. (2000) Creatine therapy in myophosphorylase deficiency (McArdle disease): A placebo-controlled crossover trial. Arch Neurol, 57, pp. 956-963.
-
(2000)
Arch Neurol
, vol.57
, pp. 956-963
-
-
Vorgerd, M.1
Grehl, T.2
Jager, M.3
Müller, K.4
Freitag, G.5
Patzold, T.6
-
26
-
-
0343953522
-
Mitochondrial impairment of human muscle in Friedreich ataxia in vivo
-
Vorgerd, M.,.Schöls, L.,.Hardt, C.,.Ristow, M.,.Epplen, J. T. and Zange, J. (2000) Mitochondrial impairment of human muscle in Friedreich ataxia in vivo. Neuromuscul Disord, 10, pp. 430-435.
-
(2000)
Neuromuscul Disord
, vol.10
, pp. 430-435
-
-
Vorgerd, M.1
Schöls, L.2
Hardt, C.3
Ristow, M.4
Epplen, J.T.5
Zange, J.6
-
27
-
-
22844440902
-
Mitochondrial impairment in patients and asymptomatic mutation carriers of Huntington's disease
-
Saft, C.,.Zange, J.,.Andrich, J.,.Müller, K.,.Lindenberg, K. and Landwehrmeyer, B. (2005) Mitochondrial impairment in patients and asymptomatic mutation carriers of Huntington's disease. Mov Disord, 20, pp. 674-679.
-
(2005)
Mov Disord
, vol.20
, pp. 674-679
-
-
Saft, C.1
Zange, J.2
Andrich, J.3
Müller, K.4
Lindenberg, K.5
Landwehrmeyer, B.6
-
28
-
-
0035068232
-
Transgenic ALS mice show increased vulnerability to the mitochondrial toxins MPTP and 3-nitropropionic acid
-
Andreassen, O. A.,.Ferrante, R. J.,.Klivenyi, P.,.Klein, A. M.,.Dedeoglu, A. and Albers, D. S. (2001) Transgenic ALS mice show increased vulnerability to the mitochondrial toxins MPTP and 3-nitropropionic acid. Exp Neurol, 168, pp. 356-363.
-
(2001)
Exp Neurol
, vol.168
, pp. 356-363
-
-
Andreassen, O.A.1
Ferrante, R.J.2
Klivenyi, P.3
Klein, A.M.4
Dedeoglu, A.5
Albers, D.S.6
-
29
-
-
0027359334
-
Superoxide dismutase activity, oxidative damage, and mitochondrial energy metabolism in familial and sporadic amyotrophic lateral sclerosis
-
Bowling, A. C.,.Schulz, J. B.,.Brown, R. H Jr. and Beal, M. F. (1993) Superoxide dismutase activity, oxidative damage, and mitochondrial energy metabolism in familial and sporadic amyotrophic lateral sclerosis. J Neurochem, 61, pp. 2322-2325.
-
(1993)
J Neurochem
, vol.61
, pp. 2322-2325
-
-
Bowling, A.C.1
Schulz, J.B.2
Brown Jr., R.H.3
Beal, M.F.4
-
30
-
-
0036321382
-
Mitochondrial DNA and respiratory chain function in spinal cords of ALS patients
-
Wiedemann, F. R.,.Manfredi, G.,.Mawrin, C.,.Beal, M. F. and Schon, E. A. (2002) Mitochondrial DNA and respiratory chain function in spinal cords of ALS patients. J Neurochem, 80, pp. 616-625.
-
(2002)
J Neurochem
, vol.80
, pp. 616-625
-
-
Wiedemann, F.R.1
Manfredi, G.2
Mawrin, C.3
Beal, M.F.4
Schon, E.A.5
-
31
-
-
0036828796
-
Mitochondrial respiratory chain function in skeletal muscle of ALS patients
-
Echaniz-Laguna, A.,.Zoll, J.,.Ribera, F.,.Tranchant, C.,.Warter, J. M. and Lonsdorfer, J. (2002) Mitochondrial respiratory chain function in skeletal muscle of ALS patients. Ann Neurol, 52, pp. 623-627.
-
(2002)
Ann Neurol
, vol.52
, pp. 623-627
-
-
Echaniz-Laguna, A.1
Zoll, J.2
Ribera, F.3
Tranchant, C.4
Warter, J.M.5
Lonsdorfer, J.6
-
32
-
-
0034811135
-
Selective changes in mitochondria respiratory properties in oxidative or glycolytic muscle fibres isolated from G93A human SOD1 transgenic mice
-
Leclerc, N.,.Ribera, F.,.Zoll, J.,.Warter, J. M.,.Poindron, P. and Lampert, E. (2001) Selective changes in mitochondria respiratory properties in oxidative or glycolytic muscle fibres isolated from G93A human SOD1 transgenic mice. Neuromuscul Disord, 11, pp. 722-727.
-
(2001)
Neuromuscul Disord
, vol.11
, pp. 722-727
-
-
Leclerc, N.1
Ribera, F.2
Zoll, J.3
Warter, J.M.4
Poindron, P.5
Lampert, E.6
-
33
-
-
0035886521
-
Impaired oxidative metabolism in exercising muscle from ALS patients
-
Siciliano, G.,.Pastorini, E.,.Pasquali, L.,.Manca, M. L.,.Iudice, A. and Murri, L. (2001) Impaired oxidative metabolism in exercising muscle from ALS patients. J Neurol Sci, 191, pp. 61-65.
-
(2001)
J Neurol Sci
, vol.191
, pp. 61-65
-
-
Siciliano, G.1
Pastorini, E.2
Pasquali, L.3
Manca, M.L.4
Iudice, A.5
Murri, L.6
-
34
-
-
0033934734
-
Mitochondria and the pathogenesis of ALS
-
Beal, M. F. (2000) Mitochondria and the pathogenesis of ALS. Brain, 123, pp. 1291-1292.
-
(2000)
Brain
, vol.123
, pp. 1291-1292
-
-
Beal, M.F.1
-
35
-
-
0020486155
-
31P NMR examination of two patients with NADH-CoQ reductase deficiency
-
Radda, G. K.,.Bore, P. J.,.Gadian, D. G.,.Ross, B. D.,.Styles, P. and Taylor, D. J. (1982) 31P NMR examination of two patients with NADH-CoQ reductase deficiency. Nature, 295, pp. 608-609.
-
(1982)
Nature
, vol.295
, pp. 608-609
-
-
Radda, G.K.1
Bore, P.J.2
Gadian, D.G.3
Ross, B.D.4
Styles, P.5
Taylor, D.J.6
|