Pseudotyped single-cycle simian immunodeficiency viruses expressing gamma interferon augment T-cell priming responses in vitro

Journal of Virology

Volumn 81, Issue 5, 2007, Pages 2187-2195

  Peng, Yue ^a   Lin, Fan Ching ^a   Verardi, Paulo H ^a   Jones, Leslie A ^a   McChesney, Michael B ^b   Yilma, Tilahun D ^a,b  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CYTOKINE; GAMMA INTERFERON; HUMAN IMMUNODEFICIENCY VIRUS VACCINE; NEF PROTEIN;

ANIMAL CELL; ANTIGENICITY; ARTICLE; CELL ACTIVATION; CONTROLLED STUDY; DENDRITIC CELL; DRUG EFFICACY; DRUG SAFETY; ENZYME LINKED IMMUNOSPOT ASSAY; HUMAN; HUMAN CELL; IN VITRO STUDY; MAJOR HISTOCOMPATIBILITY COMPLEX; NONHUMAN; PRIORITY JOURNAL; SIMIAN IMMUNODEFICIENCY VIRUS; T LYMPHOCYTE; VIRUS INFECTIVITY; VIRUS PARTICLE;

AIDS VACCINES; ANIMALS; ANTIGEN PRESENTATION; BASE SEQUENCE; CELL LINE; DENDRITIC CELLS; DNA, RECOMBINANT; GENE PRODUCTS, GAG; HUMANS; INTERFERON-GAMMA, RECOMBINANT; MACACA MULATTA; MEMBRANE GLYCOPROTEINS; RATS; SIMIAN IMMUNODEFICIENCY VIRUS; T-LYMPHOCYTES; VIRAL ENVELOPE PROTEINS;

HUMAN IMMUNODEFICIENCY VIRUS; MACACA; SIMIAN IMMUNODEFICIENCY VIRUS; VESICULAR STOMATITIS VIRUS;

EID: 33847179455     PISSN: 0022538X     EISSN: None     Source Type: Journal    
DOI: 10.1128/JVI.01879-06     Document Type: Article

References (54)

1. Ahuja, S. S., M. R. Brown, T. A. Fleisher, S. K. Ahuja, and H. L. Malech. 1996. Autocrine activation of hemopoietic progenitor-derived myelo-monocytic cells by IFN-gamma gene transfer. J. Immunol. 156:4345-4353.
2. Aiken, C. 1997. Pseudotyping human immunodeficiency virus type 1 (HIV-1) by the glycoprotein of vesicular stomatitis virus targets HIV-1 entry to an endocytic pathway and suppresses both the requirement for Nef and the sensitivity to cyclosporin A. J. Virol. 71:5871-5877.
3. Anderson, K. P., E. H. Fennie, and T. Yilma. 1988. Enhancement of a secondary antibody response to vesicular stomatitis virus "G" protein by IFN-gamma treatment at primary immunization. J. Immunol. 140:3599-3604.
4. Andrews, D. M., C. E. Andoniou, A. A. Scalzo, S. L. van Dommelen, M. E. Wallace, M. J. Smyth, and M. A. Degli-Esposti. 2005. Cross-talk between dendritic cells and natural killer cells in viral infection. Mol. Immunol. 42:547-555.
5. Baba, T. W., Y. S. Jeong, D. Pennick, R. Bronson, M. F. Greene, and R. M. Ruprecht. 1995. Pathogenicity of live, attenuated SIV after mucosal infection of neonatal macaques. Science 267:1820-1825.
6. Baba, T. W., V. Liska, A. H. Khimani, N. B. Ray, P. J. Dailey, D. Penninck, R. Bronson, M. F. Greene, H. M. McClure, L. N. Martin, and R. M. Ruprecht. 1999. Live attenuated, multiply deleted simian immunodeficiency virus causes AIDS in infant and adult macaques. Nat. Med. 5:194-203.
7. Banchereau, J., and A. K. Palucka. 2005. Dendritic cells as therapeutic vaccines against cancer. Nat. Rev. Immunol. 5:296-306.
8. Banchereau, J., and R. M. Steinman. 1998. Dendritic cells and the control of immunity. Nature 392:245-252.
9. Billiau, A. 1996. Interferon-gamma: biology and role in pathogenesis. Adv. Immunol. 62:61-130.
10. Bousso, P., and E. Robey. 2003. Dynamics of CD8+ T cell priming by dendritic cells in intact lymph nodes. Nat. Immunol. 4:579-585.
11. Burns, J. C., T. Friedmann, W. Driever, M. Burrascano, and J. K. Yee. 1993. Vesicular stomatitis virus G glycoprotein pseudotyped retroviral vectors: concentration to very high titer and efficient gene transfer into mammalian and nonmammalian cells. Proc. Natl. Acad. Sci. USA 90:8033-8037.
12. Chackerian, B., E. M. Long, P. A. Luciw, and J. Overbaugh. 1997. Human immunodeficiency virus type 1 coreceptors participate in postentry stages in the virus replication cycle and function in simian immunodeficiency virus infection. J. Virol. 71:3932-3939.
13. Chen, H. W., C. H. Pan, H. W. Huan, M. Y. Liau, J. R. Chiang, and M. H. Tao. 2001. Suppression of immune response and protective immunity to a Japanese encephalitis virus DNA vaccine by coadministration of an IL-12-expressing plasmid. J. Immunol. 166:7419-7426.
14. Clerici, M., and G. M. Shearer. 1993. A TH1→TH2 switch is a critical step in the etiology of HIV infection. Immunol. Today 14:107-111.
15. Daniel, M. D., F. Kirchhott, S. C. Czajak, P. K. Sehgal, and R. C. Desrosiers. 1992. Protective effects of a live attenuated SIV vaccine with a deletion in the nef gene. Science 258:1938-1941.
16. Dauer, M., B. Obermaier, J. Herten, C. Haerle, K. Pohl, S. Rothenfusser, M. Schnurr, S. Endres, and A. Eigler. 2003. Mature dendritic cells derived from human monocytes within 48 hours: a novel strategy for dendritic cell differentiation from blood precursors. J. Immunol. 170:4069-4076.
17. Davis, A. J., P. Li, and C. J. Burrell. 1997. Kinetics of viral RNA synthesis following cell-to-cell transmission of human immunodeficiency virus type 1. J. Gen. Virol. 78:1897-1906.
18. Evans, D. T., J. E. Bricker, and R. C. Desrosiers. 2004. A novel approach for producing lentiviruses that are limited to a single cycle of infection. J. Virol. 78:11715-11725.
19. Evans, D. T., J. E. Bricker, H. B. Sanford, S. Lang, A. Carville, B. A. Richardson, M. Piatak, Jr., J. D. Lifson, K. G. Mansfield, and R. C. Desrosiers. 2005. Immunization of macaques with single-cycle simian immunodeficiency virus (SIV) stimulates diverse virus-specific immune responses and reduces viral loads after challenge with SIVmac239. J. Virol. 79:7707-7720.
20. Flexner, C., A. Hugin, and B. Moss. 1987. Prevention of vaccinia virus infection in immunodeficient mice by vector-directed IL-2 expression. Nature 330:259-262.
21. Gherardi, M. M., J. C. Ramirez, and M. Esteban. 2000. Interleukin-12 (IL-12) enhancement of the cellular immune response against human immunodeficiency virus type 1 Env antigen in a DNA prime/vaccinia virus boost vaccine regimen is time and dose dependent: suppressive effects of IL-12 boost are mediated by nitric oxide. J. Virol. 74:6278-6286.
22. Gherardi, M. M., J. C. Ramirez, D. Rodriguez, J. R. Rodriguez, G. Sano, F. Zavala, and M. Esteban. 1999. IL-12 delivery from recombinant vaccinia virus attenuates the vector and enhances the cellular immune response against HIV-1 Env in a dose-dependent manner. J. Immunol. 162:6724-6733.
23. Giavedoni, L., S. Ahmad, L. Jones, and T. Yilma. 1997. Expression of gamma interferon by simian immunodeficiency virus increases attenuation and reduces postchallenge virus load in vaccinated rhesus macaques. J. Virol. 71:866-872.
24. Giavedoni, L. D., L. Jones, M. B. Gardner, H. L. Gibson, C. T. Ng, P. J. Barr, and T. Yilma. 1992. Vaccinia virus recombinants expressing chimeric proteins of human immunodeficiency virus and gamma interferon are attenuated for nude mice. Proc. Natl. Acad. Sci. USA 89:3409-3413.
25. Giavedoni, L. D., and T. Yilma. 1996. Construction and characterization of replication-competent simian immunodeficiency virus vectors that express gamma interferon. J. Virol. 70:2247-2251.
26. Granelli-Piperno, A., L. Zhong, P. Haslett, J. Jacobson, and R. M. Steinman. 2000. Dendritic cells, infected with vesicular stomatitis virus-pseudotyped HIV-1, present viral antigens to CD4+ and CD8+ T cells from HIV-1-infected individuals. J. Immunol. 165:6620-6626.
27. Gruber, A., J. Kan-Mitchell, K. L. Kuhen, T. Mukai, and F. Wong-Staal. 2000. Dendritic cells transduced by multiply deleted HIV-1 vectors exhibit normal phenotypes and functions and elicit an HIV-specific cytotoxic T-lymphocyte response in vitro. Blood 96:1327-1333.
28. Gundlach, B. R., H. Linhart, U. Dittmer, S. Sopper, S. Reiprich, D. Fuchs, B. Fleckenstein, G. Hunsmann, C. Stahl-Hennig, and K. Uberla. 1997. Construction, replication, and immunogenic properties of a simian immunodeficiency virus expressing interleukin-2. J. Virol. 71:2225-2232.
29. Heath, A. W., and J. H. Playfair. 1992. Cytokines as immunological adjuvants. Vaccine 10:427-434.
30. Johnson, H. M., and B. A. Torres. 1983. Recombinant mouse interferon-gamma regulation of antibody production. Infect. Immun. 41:546-548.
31. Karn, J. 1999. Tackling Tat. J. Mol. Biol. 293:235-254.
32. Kim, S. S, N. Kothari, X. J. You, W. E. Robinson, Jr., T. Schnell, K. Uberla, and H. Fan. 2001. Generation of replication-defective helper-free vectors based on simian immunodeficiency virus. Virology 282:154-167.
33. Kohonen-Corish, M. R., N. J. King, C. E. Woodhams, and I. A. Ramshaw. 1990. Immunodeficient mice recover from infection with vaccinia virus expressing interferon-gamma. Eur. J. Immunol. 20:157-161.
34. Kuate, S., C. Stahl-Hennig, H. Stoiber, G. Nchinda, A. Floto, M. Franz, U. Sauermann, S. Bredl, L. Demi, R. Ignatius, S. Norley, P. Racz, K. Tenner-Racz, R. M. Steinman, R. Wagner, and K. Uberla. 2006. Immunogenicity and efficacy of immunodeficiency virus-like particles pseudotyped with the G protein of vesicular stomatitis virus. Virology 351:133-144.
35. Kuate, S., C. Stahl-Hennig, P. ten Haaft, J. Heeney, and K. Uberla. 2003. Single-cycle immunodeficiency viruses provide strategies for uncoupling in vivo expression levels from viral replicative capacity and for mimicking live-attenuated SIV vaccines. Virology 313:653-662.
36. Legrand, F. A., P. H. Verardi, K. S. Chan, Y. Peng, L. A. Jones, and T. D. Yilma. 2005. Vaccinia viruses with a serpin gene deletion and expressing IFN-gamma induce potent immune responses without detectable replication in vivo. Proc. Natl. Acad. Sci. USA 102:2940-2945.
37. Lichty, B. D., A. T. Power, D. F. Stojdl, and J. C. Bell. 2004. Vesicular stomatitis virus: re-inventing the bullet. Trends Mol. Med. 10:210-216.
38. Liu, Y. J., H. Kanzler, V. Soumelis, and M. Gilliet. 2001. Dendritic cell lineage, plasticity and cross-regulation. Nat. Immunol. 2:585-589.
39. Marsac, D., D. Loirat, C. Petit, O. Schwartz, and M. L. Michel. 2002. Enhanced presentation of major histocompatibility complex class I-restricted human immunodeficiency virus type 1 (HIV-1) Gag-specific epitopes after DNA immunization with vectors coding for vesicular stomatitis virus glycoprotein-pseudotyped HIV-1 Gag particles. J. Virol. 76:7544-7553.
40. Mehlhop, E., L. A. Villamide, I. Frank, A. Gettie, C. Santisteban, D. Messmer, R. Ignatius, J. D. Lifson, and M. Pope. 2002. Enhanced in vitro stimulation of rhesus macaque dendritic cells for activation of SIV-specific T cell responses. J. Immunol. Methods 260:219-234.
41. Moser, M., and K. M. Murphy. 2000. Dendritic cell regulation of TH1-TH2 development. Nat. Immunol. 1:199-205.
42. Nakamura, M., T. Manser, G. D. Pearson, M. J. Daley, and M. L. Gefter. 1984. Effect of IFN-gamma on the immune response in vivo and on gene expression in vitro. Nature 307:381-382.
43. Pahar, B., J. Li, T. Rourke, C. J. Miller, and M. B. McChesney. 2003. Detection of antigen-specific T cell interferon gamma expression by ELISPOT and cytokine flow cytometry assays in rhesus macaques. J. Immunol. Methods 282:103-115.
44. Pan, J., M. Zhang, J. Wang, Q. Wang, D. Xia, W. Sun, L. Zhang, H. Yu, Y. Liu, and X. Cao. 2004. Interferon-gamma is an autocrine mediator for dendritic cell maturation. Immunol. Lett. 94:141-151.
45. Partidos, C. D., and S. Muller. 2005. Decision-making at the surface of the intact or barrier disrupted skin: potential applications for vaccination or therapy. Cell. Mol. Life Sci. 62:1418-1424.
46. Robert-Guroff, M., M. Popovic, S. Gartner, P. Markham, R. C. Gallo, and M. S. Reitz. 1990. Structure and expression of tat-, rev-, and nef-specific transcripts of human immunodeficiency virus type 1 in infected lymphocytes and macrophages. J. Virol. 64:3391-3398.
47. Rose, N. F., A. Roberts, L. Buonocore, and J. K. Rose. 2000. Glycoprotein exchange vectors based on vesicular stomatitis virus allow effective boosting and generation of neutralizing antibodies to a primary isolate of human immunodeficiency virus type 1. J. Virol. 74:10903-10910.
48. Shankar, G., L. A. Pestano, and M. L. Bosch. 2003. Interferon-gamma added during bacillus Calmette-Guerin induced dendritic cell maturation stimulates potent Th1 immune responses. J. Transl. Med. 1:7.
49. Snijders, A., P. Kalinski, C. M. Hilkens, and M. L. Kapsenberg. 1998. High-level IL-12 production by human dendritic cells requires two signals. Int. Immunol. 10:1593-1598.
50. Villinger, F., S. S. Brar, A. Mayne, N. Chikkala, and A. A. Ansari. 1995. Comparative sequence analysis of cytokine genes from human and nonhuman primates. J. Immunol. 155:3946-3954.
51. Wu, M., S. Hussain, Y. H. He, R. Pasula, P. A. Smith, and W. J. Martin II. 2001. Genetically engineered macrophages expressing IFN-γ restore alveolar immune function in scid mice. Proc. Natl. Acad. Sci. USA 98:14589-14594.
52. Wyand, M. S., K. H. Manson, A. A. Lackner, and R. C. Desrosiers. 1997. Resistance of neonatal monkeys to live attenuated vaccine strains of simian immunodeficiency virus. Nat. Med. 3:32-36.
53. Yilma, T., S. Owens, E. H. Fennie, and K. P. Anderson. 1989. Enhancement of primary and secondary immune responses by interferon-gamma. Adv. Exp. Med. Biol. 251:145-152.
54. Zufferey, R. 2000. Production of high-liter lentiviral vectors, p. 4.21.1-4.21.12. In J. N. Crawley et al. (ed.), Current protocols in neurosciences, unit 4.21. John Wiley & Sons, New York, NY.