Activation of hEAG1 potassium channels by arachidonic acid

Pflugers Archiv European Journal of Physiology

Volumn 453, Issue 6, 2007, Pages 891-903

  Gavrilova Ruch, Oxana ^a   Schönherr, Roland ^a   Heinemann, Stefan H ^a  

^a FRIEDRICH SCHILLER UNIVERSITY JENA   (Germany)

Author keywords

Arachidonic acid; Cell proliferation; Channel opener; EAG potassium channel; IGR1; Polyunsaturated fatty acids

Indexed keywords

ARACHIDONIC ACID; ETHYLHEPTYL[4 (4 NITROPHENYL)BUTYL]AMINE; FATTY ACID; ICOSAPENTAENOIC ACID; LINOLENIC ACID; OLEIC ACID; POLYUNSATURATED FATTY ACID; POTASSIUM CHANNEL BLOCKING AGENT; POTASSIUM CHANNEL HERG; UNCLASSIFIED DRUG; VOLTAGE GATED POTASSIUM CHANNEL;

ANIMAL CELL; ARTICLE; CELL METABOLISM; CELL PROLIFERATION; CONTROLLED STUDY; HUMAN; HUMAN CELL; MELANOMA CELL; MEMBRANE STEADY POTENTIAL; NONHUMAN; PRIORITY JOURNAL; PROTEIN FUNCTION;

ANIMALS; ARACHIDONIC ACID; CELL DIVISION; CELL LINE, TUMOR; CHO CELLS; CRICETINAE; CRICETULUS; ETHER-A-GO-GO POTASSIUM CHANNELS; FATTY ACIDS, UNSATURATED; HUMANS; ION CHANNEL GATING; MELANOMA; MEMBRANE POTENTIALS; MODELS, BIOLOGICAL; OOCYTES; PATCH-CLAMP TECHNIQUES; TRANSFECTION; XENOPUS LAEVIS;

EID: 33847145806     PISSN: 00316768     EISSN: 14322013     Source Type: Journal    
DOI: 10.1007/s00424-006-0173-3     Document Type: Article

References (42)

1. + channels. J Membr Biol 182:1-15
2. Broughton SJ, Kitamoto T, Greenspan RJ (2004) Excitatory and inhibitory switches for courtship in the brain of Drosophila melanogaster. Curr Biol 14:538-547
3. Camacho J (2006) Ether à go-go potassium channels and cancer. Cancer Lett 233:1-9
4. Capdevila J, Gil L, Orellana M, Marnett LJ, Mason JI, Yadagiri P, Falck JR (1988) Inhibitors of cytochrome P-450-dependent arachidonic acid metabolism. Arch Biochem Biophys 261:257-263
5. + channels in hippocampal CA1 pyramidal neurons. J Neurosci 19:8163-8171
6. Denkins Y, Kempf D, Ferniz M, Nileshwar S, Marchetti D (2005) Role of omega-3 polyunsaturated fatty acids on cyclooxygenase-2 metabolism in brain-metastatic melanoma. J Lipid Res 46:1278-1284
7. 3 cells. Am J Physiol Cell Physiol 279:C1211-C1219
8. Farias LM, Ocana DB, Diaz L, Larrea F, Avila-Chavez E, Cadena A, Hinojosa LM, Lara G, Villanueva LA, Vargas C, Hernandez-Gallegos E, Camacho-Arrayo I, Duenas-Gonzalez A, Perez-Cardenas E, Pardo LA, Morales A, Taja-Chayeb L, Escamilla J, Sanchez-Pena C, Camacho J (2004) Ether à go-go potassium channels as human cervical cancer markers. Cancer Res 64:6996-7001
9. Gavrilova-Ruch O, Schönherr K, Gessner G, Schönherr R, Klapperstück T, Wohlrab W, Heinemann SH (2002) Effects of imipramine on ion channels and proliferation of IGR1 melanoma cells. J Membr Biol 188:137-149
10. Gessner G, Heinemann SH (2003) Inhibition of hEAG1 and hERG1 potassium channels by clofilium and its tertiary analog LY97241. Br J Pharmacol 138:161-171
11. Guizy M, Arias C, David M, González T, Valenzuela C (2005) Ω-3 and Ω-6 polyunsaturated fatty acids block HERG channels. Am J Physiol Cell Physiol 289:C1251-C1260
12. Hamilton KL, Syme CA, Devor DC (2003) Molecular localisation of the inhibitory arachidonic acid binding site to the pore of hIK1. J Biol Chem 278:16690-16697
13. + channels. Proc Natl Acad Sci USA 103:2886-2891
14. Honoré E, Barchanin J, Attali B, Lesage F, Lazdunski M (1994) External blockade of the major cardiac delayed-rectifier K* channel (Kv1.5) by polyunsaturated fatty acids. Proc Natl Acad Sci USA 91:1937-1944
15. Ju M, Wray D (2002) Molecular identification and characterisation of the human eag 2 potassium channel. FEBS Lett 524:204-210
16. i. Pflügers Arch 442:952-960
17. Kogteva GS, Bezuglov VV (1998) Unsaturated fatty acids as endogenous bioregulators. Biochemistry (Moscow) 63:4-12
18. Lauritzen I, Blondeau N, Heurteaux C, Widmann C, Romey G, Lazdunski M (2000) Polyunsaturated fatty acids are potent neuroprotectors. EMBO J 19:1784-1793
19. Liu Y, Liu D, Heath L, Meyers DM, Krafte DS, Wagoner PK, Silvia CP, Yu W, Curran ME (2001) Direct activation of an inwardly rectifying potassium channel by arachidonic acid. Mol Pharmacol 59:1061-1068
20. + channel, ROMK1, in arachidonic acid-mediated inhibition. Am J Physiol 274:F175-F181
21. Nie D, Honn KV (2004) Eicosanoid regulation of angiogenesis in tumors. Semin Thromb Hemost 30:119-125
22. Occhiodoro T, Bernheim L, Liu JH, Bijlenga P, Sinnreich M, Bader CR, Fischer-Lougheed J (1998) Cloning of a human ether-a-go-go potassium channel expressed in myoblasts at the onset of fusion. FEBS Lett 434:177-182
23. + channels by membrane lipids. Science 304:265-270
24. + channels. EMBO J 18:5540-5547
25. Pardo LA (2004) Voltage-gated potassium channels in cell proliferation. Physiology 19:285-292
26. + channel. EMBO J 15:4283-4290
27. Piomelli D (1996) Arachidonic acid in cell signalling. Springer, Berlin Heidelberg New York, 195 pp
28. 2 gating site. J Biol Chem 276:14855-14860
29. + channels in brain. J Neurosci 21:4609-4624
30. Sanguinetti MC, Tristani-Firouzi M (2006) hERG potassium channels and cardiac arrhythmia. Nature 440:463-469
31. + currents by thyrotropin-releasing hormone in anterior pituitary cells via the native signal cascade. J Physiol 532:143-163
32. Schönherr R (2005) Clinical relevance of ion channels for diagnosis and therapy of cancer. J Membr Biol 205:175-184
33. Schönherr R, Gessner G, Löber K, Heinemann SH (2002) Functional distinction of human EAG1 and EAG2 potassium channels. FEBS Lett 514:204-208
34. 2+/calmodulin. EMBO J 19:3263-3271
35. + channel. Neuron 35:935-949
36. 2+ modulates voltage-dependent activation in ether-a-go-go potassium channels by binding between transmembrane segments S2 and S3. J Gen Physiol 116:663-678
37. Snyders DJ, Tamkun MM, Bennet PB (1993) A rapidly activating and slowly inactivation potassium channel cloned from human heart. Functional analysis after stable mammalian cell culture expression. J Gen Physiol 101:513-543
38. Stühmer W, Alves F, Hartung F, Zientkowska M, Pardo LA (2006) Potassium channels as tumour markers. FEBS Lett 580:2850-2852
39. + regulates activation of rat eag potassium channel. Pflügers Arch 432:301-312
40. + currents by arachidonic acid. J Neurosci 16:2522-2531
41. + channel function by phospholipid metabolites. Br J Pharmacol 141:586-599
42. Zheng HF, Li XL, Jin ZY, Sun JB, Li ZB, Xu WX (2005) Effects of unsaturated fatty acids on calcium-activated potassium current in gastric myocytes of guinea pigs. World J Gastroenterol 11:672-675