Tributyltin and triphenyltin inhibit osteoclast differentiation through a retinoic acid receptor-dependent signaling pathway

Biochemical and Biophysical Research Communications

Volumn 355, Issue 1, 2007, Pages 10-15

  Yonezawa, Takayuki ^a   Hasegawa, Shin ichi ^a   Ahn, Jae Yong ^a   Cha, Byung Yoon ^a   Teruya, Toshiaki ^a   Hagiwara, Hiromi ^b   Nagai, Kazuo ^a   Woo, Je Tae ^a  

^a CHUBU UNIVERSITY   (Japan)

^b TOIN UNIVERSITY OF YOKOHAMA   (Japan)

Author keywords

Bone resorption; Organotin compound; Osteoclast; Tributyltin; Triphenyltin

Indexed keywords

DIBUTYLTIN; ENDOCRINE DISRUPTOR; MONOBUTYLTIN; NUCLEAR FACTOR OF ACTIVATED T CELLS C1; ORGANOTIN COMPOUND; OSTEOCLAST DIFFERENTIATION FACTOR; RECEPTOR BLOCKING AGENT; RETINOIC ACID RECEPTOR; RO 41 5253; TRANSCRIPTION FACTOR NFAT; TRIBUTYLTIN; TRIPHENYLTIN; UNCLASSIFIED DRUG;

AGRICULTURE; ANIMAL CELL; ARTICLE; CELL DIFFERENTIATION; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; INDUSTRY; MONOCYTE; MOUSE; NONHUMAN; OSTEOCLAST; OSTEOCLASTOGENESIS; OSTEOLYSIS; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN INDUCTION; PROTEIN PROTEIN INTERACTION; SIGNAL TRANSDUCTION;

ANIMALS; BONE RESORPTION; CELL DIFFERENTIATION; CELL LINE; CELL SURVIVAL; MACROPHAGES; MICE; ORGANOTIN COMPOUNDS; OSTEOCLASTS; RECEPTORS, RETINOIC ACID; RETINOID X RECEPTORS; SIGNAL TRANSDUCTION; TRIALKYLTIN COMPOUNDS;

EID: 33847009425     PISSN: 0006291X     EISSN: 10902104     Source Type: Journal    
DOI: 10.1016/j.bbrc.2006.12.237     Document Type: Article

References (29)

1. Harino H., Fukushima M., and Kawai S. Accumulation of butyltin and phenyltin compounds in various fish species. Arch. Environ. Contam. Toxicol. 39 (2000) 13-19
2. Kannan K., Corsolini S., Focardi S., Tanabe S., and Tatsukawa R. Accumulation pattern of butyltin compounds in dolphin, tuna, and shark collected from Italian coastal waters. Arch. Environ. Contam. Toxicol. 31 (1996) 19-23
3. Horiguchi T., Shiraishi H., Shimizu M., and Morita M. Effects of triphenyltin chloride and five other organotin compounds on the development of imposex in the rock shell, Thais clavigera. Environ. Pollut. 95 (1997) 85-91
4. Matthiessen P., and Gibbs P.E. Critical appraisal of the evidence for tributyltin-mediated endocrine disruption in mollusks. Environ. Toxicol. Chem. 17 (1998) 37-43
5. Snoeij N.J., Penninks A.H., and Seinen W. Biological activity of organotin compounds-an overview. Environ. Res. 44 (1987) 335-353
6. Watanabe H., Adachi R., Hirayama A., Kasahara T., and Suzuki K. Triphenyltin enhances the neutrophilic differentiation of promyelocytic HL-60 cells. Biochem. Biophys. Res. Commun. 306 (2003) 26-31
7. Grun F., Watanabe H., Zamanian Z., Maeda L., Arima K., Cubacha R., Gardiner D.M., Kanno J., Iguchi T., and Blumberg B. Endocrine-disrupting organotin compounds are potent inducers of adipogenesis in vertebrates. Mol. Endocrinol. 20 (2006) 2141-2155
8. Inadera H., and Shimomura A. Environmental chemical tributyltin augments adipocyte differentiation. Toxicol. Lett. 159 (2005) 226-234
9. Kanayama T., Kobayashi N., Mamiya S., Nakanishi T., and Nishikawa J. Organotin compounds promote adipocyte differentiation as agonists of the peroxisome proliferator-activated receptor gamma/retinoid X receptor pathway. Mol. Pharmacol. 67 (2005) 766-774
10. Tsukamoto Y., Ishihara Y., Miyagawa-Tomita S., and Hagiwara H. Inhibition of ossification in vivo and differentiation of osteoblasts in vitro by tributyltin. Biochem. Pharmacol. 68 (2004) 739-746
11. Rodan G.A., and Martin T.J. Therapeutic approaches to bone diseases. Science 289 (2000) 1508-1514
12. Suda T., Takahashi N., Udagawa N., Jimi E., Gillespie M.T., and Martin T.J. Modulation of osteoclast differentiation and function by the new members of the tumor necrosis factor receptor and ligand families. Endocr. Rev. 20 (1999) 345-357
13. Boyle W.J., Simonet W.S., and Lacey D.L. Osteoclast differentiation and activation. Nature 423 (2003) 337-342
14. Lee Z.H., and Kim H.H. Signal transduction by receptor activator of nuclear factor κB in osteoclasts. Biochem. Biophys. Res. Commun. 305 (2003) 211-214
15. Woo J.T., Nakagawa H., Notoya M., Yonezawa T., Udagawa N., Lee I.S., Ohnishi M., Hagiwara H., and Nagai K. Quercetin suppresses bone resorption by inhibiting the differentiation and activation of osteoclasts. Biol. Pharm. Bull. 27 (2004) 504-509
16. Cooke G.M. Effect of organotins on human aromatase activity in vitro. Toxicol. Lett. 126 (2002) 121-130
17. Saitoh M., Yanase T., Morinaga H., Tanabe M., Mu Y.M., Nishi Y., Nomura M., Okabe T., Goto K., Takayanagi R., and Nawata H. Tributyltin or triphenyltin inhibits aromatase activity in the human granulosa-like tumor cell line KGN. Biochem. Biophys. Res. Commun. 289 (2001) 198-204
18. Nakanishi T., Nishikawa J., Hiromori Y., Yokoyama H., Koyanagi M., Takasuga S., Ishizaki J., Watanabe M., Isa S., Utoguchi N., Itoh N., Kohno Y., Nishihara T., and Tanaka K. Trialkyltin compounds bind retinoid X receptor to alter human placental endocrine functions. Mol. Endocrinol. 19 (2005) 2502-2516
19. Nishikawa J., Mamiya S., Kanayama T., Nishikawa T., Shiraishi F., and Horiguchi T. Involvement of the retinoid X receptor in the development of imposex caused by organotins in gastropods. Environ. Sci. Technol. 38 (2004) 6271-6276
20. Ishimi Y., Ohumura M., Wang X., Yamaguchi M., and Ikegami S. Inhibition by carotenoids and retinoic acid of osteoclast-like cell formation induced by bone-resorbing agents in vitro. J. Clin. Biochem. Nutr. 27 (1999) 113-122
21. Wang X., Wu J., Shidoji Y., Muto Y., Ohishi N., Yagi K., Ikegami S., Shinki T., Udagawa N., Suda T., and Ishimi Y. Effects of geranylgeranoic acid in bone: induction of osteoblast differentiation and inhibition of osteoclast formation. J. Bone Miner. Res. 17 (2002) 91-100
22. Astrom A., Pettersson U., Krust A., Chambon P., and Voorhees J.J. Retinoic acid and synthetic analogs differentially activate retinoic acid receptor dependent transcription. Biochem. Biophys. Res. Commun. 173 (1990) 339-345
23. Harmon M.A., Boehm M.F., Heyman R.A., and Mangelsdorf D.J. Activation of mammalian retinoid X receptors by the insect growth regulator methoprene. Proc. Natl. Acad. Sci. USA. 92 (1995) 6157-6160
24. Apfel C., Bauer F., Crettaz M., Forni L., Kamber M., Kaufmann F., LeMotte P., Pirson W., and Klaus M. A retinoic acid receptor alpha antagonist selectively counteracts retinoic acid effects. Proc. Natl. Acad. Sci. USA. 89 (1992) 7129-7133
25. Blumberg B., and Evans R.M. Orphan nuclear receptors-new ligands and new possibilities. Genes Dev. 12 (1998) 3149-3155
26. Aranda A., and Pascual A. Nuclear hormone receptors and gene expression. Physiol. Rev. 81 (2001) 1269-1304
27. Pfahl M. Nuclear receptor/AP-1 interaction. Endocr. Rev. 14 (1993) 651-658
28. Kannan K., Senthilkumar K., and Giesy J.P. Occurrence of butyltin compounds in human blood. Environ. Sci. Technol. 33 (1999) 1776-1779
29. Takahashi S., Mukai H., Tanabe S., Sakayama K., Miyazaki T., and Masuno H. Butyltin residues in livers of humans and wild terrestrial mammals and in plastic products. Environ. Pollut. 106 (1999) 213-218