Inhibition of ossification in vivo and differentiation of osteoblasts in vitro by tributyltin

Biochemical Pharmacology

Volumn 68, Issue 4, 2004, Pages 739-746

  Tsukamoto, Yu ^a   Ishihara, Yoko ^b   Miyagawa Tomita, Sachiko ^c   Hagiwara, Hiromi ^a  

^a TOKYO INSTITUTE OF TECHNOLOGY   (Japan)

^b TOKYO WOMEN'S MEDICAL UNIVERSITY   (Japan)

^c TOKYO MEDICAL AND DENTAL UNIVERSITY   (Japan)

Author keywords

alkaline phosphatase; ALPase; days post coitus; DBT; dibutyltin dichloride; dpc; GAPDH; glyceraldehyde 3 phosphate dehydrogenase; MBT; monobutyltin trichloride; rat calvarial osteoblast like cells; ROB cells; RT PCR

Indexed keywords

ALKALINE PHOSPHATASE; AMINOGLUTETHIMIDE; AROMATASE; AROMATASE INHIBITOR; CALCIUM; DIBUTYLTIN DICHLORIDE; MESSENGER RNA; MONOBUTYLTIN TRICHLORIDE; OSTEOCALCIN; TRIBUTYLTIN; TRIBUTYLTIN CHLORIDE; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ARTICLE; BONE METABOLISM; CALVARIA; CELL DIFFERENTIATION; CELL VIABILITY; CONTROLLED STUDY; DIFFERENTIATION; FEMALE; MOUSE; NONHUMAN; OSSIFICATION; OSTEOBLAST; PRIORITY JOURNAL;

ANIMALS; CELL DIFFERENTIATION; CELLS, CULTURED; EMBRYONIC AND FETAL DEVELOPMENT; FEMALE; MICE; MICE, INBRED BALB C; OSTEOBLASTS; OSTEOGENESIS; RATS; RATS, WISTAR; TRIALKYLTIN COMPOUNDS;

EID: 3242679664     PISSN: 00062952     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bcp.2004.04.020     Document Type: Article

References (36)

1. Ishaaya I., Engel J.L., Casida J.E. Dietary triorganotins affect lymphatic tissues and blood composition of mice. Pestic Biochem Physiol. 6:1976;270-279
2. Snoeij N.J., Penninks A.H., Seinen W. Dibutyltin and tributyltin compounds induce thymus atrophy in rats due to a selective action on thymic lymphoblasts. Int J Immunopharmacol. 10:1988;891-899
3. Horiguchi T., Hyeno-Seo C., Shiraishi H., Shibata Y., Soma M., Morita M., et al. Field studies on imposex and organotin accumulation in the rock shell, Thais clavigera, from the Seto Inland Sea and the Sanriku region. Jpn. Sci Total Environ. 214:1998;65-70
4. Matthiessen P., Gibbs P.E. Critical appraisal of the evidence for tributyltin-mediated endocrine disruption in mollusks. Environ Toxicol Chem. 17:1998;37-43
5. Aw T.Y., Nicotera P., Manzo L., Orrenius S. Tributyltin stimulates apoptosis in rat thymocytes. Arch Biochem Biophys. 283:1990;46-50
6. Raffray M., McCarthy D., Snowden R.T., Cohen G.M. Apoptosis as a mechanism of tributyltin cytotoxicity to thymocytes: relationship of apoptotic markers to biochemical and cellular effects. Toxicol Appl Pharmacol. 119:1993;122-130
7. Ghibelli L., Maresca V., Coppola S., Gualandi G. Protease inhibitors block apoptosis at intermediate stages: a compared analysis of DNA fragmentation and apoptotic nuclear morphology. FEBS Lett. 377:1995;9-14
8. Cooke G.M. Effect of organotins on human aromatase activity in vitro. Toxicol Lett. 126:2002;121-130
9. Saitoh M., Yanase T., Morinaga H., Tanabe M., Mu Y.M., Nishi Y., et al. Tributyltin or triphenyltin inhibits aromatase activity in the human granulose-like tumor cell line KGN. Biochem Biophys Res Commun. 289:2001;198-204
10. Hagiwara H., Inoue A., Yamaguchi A., Yokose S., Furuya M., Tanaka S., et al. cGMP produced in response to ANP and CNP regulates proliferation and differentiation of osteoblastic cells. Am. J. Physiol. 270:1996;C1311-C1318
11. Inoue A., Hiruma Y., Hirose S., Yamaguchi A., Furuya M., Tanaka S., et al. Stimulation by C-type natriuretic peptide of the differentiation of clonal osteoblastic MC3T3-E1 cells. Biochem Biophys Res Commun. 221:1996;703-707
12. Bresford J.N., Graves S.E., Smoothy C.A. Formation of mineralized nodules by bone derived cells in vitro: a model of bone formation? Am J Med Genet. 45:1993;163-178
13. Liu F., Malaval L., Gupta A.K., Aubin J.E. Simultaneous detection of multiple bone-related mRNAs and protein expression during osteoblast differentiation: polymerase chain reaction and immunocytochemical studies at the single cell level. Dev Biol. 166:1994;220-234
14. Stein G.S., Lian J.B., Owen T.A. Relationship of cell growth to the regulation of tissue-specific gene expression during osteoblast differentiation. FASEB J. 4:1990;3111-3123
15. Hagiwara H., Naruse M., Adachi C., Inoue A., Hiruma Y., Otsuka E., et al. Ipriflavone down-regulates endothelin receptor levels during differentiation of rat calvarial osteoblast-like cells. J Biochem (Tokyo). 126:1999;168-173
16. Yuhara S., Kasagi S., Inoue A., Otsuka E., Hirose S., Hagiwara H. The effects of nicotine on cultured cells suggest that it can influence the formation and resorption of bone. Eur J Pharmacol. 383:1999;387-393
17. Yamagishi T., Otsuka E., Hagiwara H. Reciprocal control of expression of mRNAs for osteoclast differentiation factor and osteoprotegerin in osteogenic stromal cells by genistein: evidence for the involvement of topoisomerase II in osteoclastogenesis. Endocrinology. 142:2001;3632-3637
18. Notoya M., Tsukamoto Y., Nishimura H., Nagai K., Hagiwara H. Quercetin, a flavonoid, inhibits the proliferation, differentiation, and mineralization of osteoblasts in vitro. Eur J Pharmacol. 485:2004;89-96
19. Naruse M., Ishihara Y., Miyagawa-Tomita S., Koyama A., Hagiwara H. 3-Methylcholanthrene, which binds to the arylhydrocarbon receptor, inhibits proliferation and differentiation of osteoblasts in vitro and ossification in vivo. Endocrinology. 143:2002;3575-3581
20. Naruse M., Otsuka E., Naruse M., Ishihara Y., Miyagawa-Tomita S., Hagiwara H. Inhibition of osteoclast formation by 3-methylcholanthrene, a ligand for arylhydrocarbon receptor: suppression of osteoclast differentiation factor in osteogenic cells. Biochem Pharmacol. 67:2004;119-127
21. Hogan B, Beddington R, Costantini F, Lacy E. Manipulating the mouse embryo. A laboratory manual. 2nd ed. New York: Cold Spring Harbor Laboratory Press; 1994.
22. Kaufman MH. The atlas of mouse development. San Diego: Academic Press; 1992.
23. Adeeko A., Li D., Forsyth D.S., Casey V., Cooke G.M., Barthelemy J., et al. Effects of in utero tributyltin chloride exposure in the rat on pregnancy outcome. Toxicol Sci. 74:2003;407-415
24. Shozu M., Zhao Y., Simpson E.R. TGF-β1 stimulates expression of the aromatase (CYP19) gene in human osteoblast-like cells and THP-1 cells. Mol Cell Endocrinol. 160:2000;123-133
25. Takayanagi R., Goto K., Suzuki S., Tanaka S., Shimoda S., Nawata H. Dehydroepiandrosterone (DHEA) as a possible source for estrogen formation in bone cells: correlation between bone mineral density and serum DHEA-sulfate concentration in postmenopausal women, and the presence of aromatase to be enhanced by 1,25-dihydroxyvitamin D3 in human osteoblasts. Mech Ageing Dev. 123:2002;1107-1114
26. Kawanishi T., Kikuchi T., Asoh H., Shibayama R., Kawai H., Ohata H., et al. Effect of tributyltin chloride on the release of calcium ion from intracellular calcium stores in rat hepatocytes. Biochem Pharmacol. 62:2001;863-872
27. Corsini E., Viviani B., Marinovich M., Galli C.L. Role of mitochondria and calcium ions in tributyltin-induced gene regulatory pathways. Toxicol Appl Pharmacol. 145:1997;74-81
28. Viviani B., Rossi A.D., Chow S.C., Nicotera P. Organotin compounds induce calcium overload and apoptosis in PC12 cells. Neurotoxicology. 16:1995;19-25
29. 2+. Toxicol Appl Pharmacol. 168:2000;200-207
30. Duarte W.R., Shibata T., Takenaga K., Takahashi E., Kubota K., Ohya K., et al. S100A4: a novel negative regulator of mineralization and osteoblast differentiation. J Bone Miner Res. 18:2003;493-501
31. Bilezikian JP, Raisz LG, Rodan GA. Principles of bone biology. San Diego: Academic Press; 1996.
32. Whalen M.M., Loganathan B.G., Kannan K. Immunotoxicity of environmentally relevant concentrations of butyltins on human natural killer cells in vitro. Environ Res. 81:1999;108-116
33. Iwata H., Tanabe S., Mizuno T., Tatsukawa R. High accumulation of toxic butyltins in marine mammals from Japanese coastal waters. Environ Sci Technol. 29:1995;2959-2962
34. Kannan K., Senthilkumar K., Longanathan B.G., Takahashi S., Odell D.K., Tanabe S. Elevated accumulation of tributyltin and its breakdown products in bottlenose dolphins (Tursiops truncates) found stranded along the US Atlantic and Gulf coasts. Environ Sci Technol. 31:1997;296-301
35. Tanabe S., Prudente M., Mizuno T., Hasegawa J., Iwata H., Miyazaki N. Butyltin concentration in marine mammals from North Pacific and Asian coastal waters. Environ Sci Technol. 32:1998;193-198
36. Kannan K., Senthilkumar K., Giesy J.P. Occurrence of butyltin compounds in human blood. Environ Sci Technol. 33:1999;1776-1779