3-Hydroxychromones as cyclin-dependent kinase inhibitors: Synthesis and biological evaluation

Bioorganic and Medicinal Chemistry Letters

Volumn 17, Issue 5, 2007, Pages 1284-1287

  Lee, Jinho ^a   Park, Taesik ^b   Jeong, Shinwu ^b   Kim, Kyoung Hee ^b   Hong, Changyong ^b  

^a Keimyung University   (South Korea)

^b LG Chemical Ltd   (South Korea)

Author keywords

3 Hydroxychromone; CDK2; Isothiazolidine 1,1 dioxide

Indexed keywords

3 HYDROXYCHROMONE DERIVATIVE; CHROMONE DERIVATIVE; CYCLIN DEPENDENT KINASE 1; CYCLIN DEPENDENT KINASE 2; CYCLIN DEPENDENT KINASE INHIBITOR; ISOTHIAZOLIDINE 1,1 DIOXIDE DERIVATIVE; THIAZOLIDINE DERIVATIVE; UNCLASSIFIED DRUG;

ANTINEOPLASTIC ACTIVITY; ARTICLE; CANCER CELL CULTURE; CANCER INHIBITION; CELL PROLIFERATION; CONTROLLED STUDY; DRUG ACTIVITY; DRUG SCREENING; DRUG SYNTHESIS; ENZYME INHIBITION; HUMAN; HUMAN CELL;

ANTINEOPLASTIC AGENTS; BINDING SITES; CELL LINE, TUMOR; CELL SURVIVAL; CHROMONES; CYCLIN-DEPENDENT KINASE 2; CYCLIN-DEPENDENT KINASE INHIBITOR PROTEINS; HUMANS; INHIBITORY CONCENTRATION 50; PROTEIN BINDING; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 33846983918     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmcl.2006.12.011     Document Type: Article

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