Contribution of a Single Hydrogen Bond between βHis81 of MHC Class II I-Ek and the Bound Peptide to the pH-Dependent Thermal Stability

Microbiology and Immunology

Volumn 48, Issue 1, 2004, Pages 53-57

  Saito, Keigo ^a   Oda, Masayuki ^b   Sarai, Akinori ^c   Azuma, Takachika ^a   Kozono, Haruo ^a  

^a TOKYO UNIVERSITY OF SCIENCE   (Japan)

^b KYOTO PREFECTURAL UNIVERSITY   (Japan)

^c KYUSHU INSTITUTE OF TECHNOLOGY   (Japan)

Author keywords

MHC class II; Peptides exchange; Thermal stability

Indexed keywords

HEMOGLOBIN; HISTIDINE; MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 2; TYROSINE;

ACIDITY; AMINO ACID SUBSTITUTION; ARTICLE; CONTROLLED STUDY; DIFFERENTIAL SCANNING CALORIMETRY; ENERGY TRANSFER; ENTHALPY; HYDROGEN BOND; HYDROPHILICITY; MAJOR HISTOCOMPATIBILITY COMPLEX; MUTANT; PH; PROTEIN BINDING; PROTEIN DENATURATION; TEMPERATURE; THERMOSTABILITY; WILD TYPE;

EID: 0942286863     PISSN: 03855600     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1348-0421.2004.tb03487.x     Document Type: Article

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