Carvedilol restore cardiac calcium release channel structure and function in heart failure

International Journal of Cardiology

Volumn 116, Issue 2, 2007, Pages 231-235

  Xue, Shu ren ^a,b   Xue, Yu ^c   Xue, Rong ^d  

^a Cardiovascular Institute of Hang Zhou   (China)

^b IMPERIAL COLLEGE LONDON   (United Kingdom)

^c Shang Hai Fu Xing Medicine and Pharmacology Company   (China)

^d FUDAN UNIVERSITY   (China)

Author keywords

Calcium; Carvedilol; Heart failure; Ion channels; Sarcoplasmic reticulum

Indexed keywords

CARVEDILOL; CYCLIC AMP DEPENDENT PROTEIN KINASE; RYANODINE RECEPTOR 2;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; ARTIFICIAL HEART PACEMAKER; CONTROLLED STUDY; DISEASE SEVERITY; DOG; HEART FAILURE; HEART PACING; NONHUMAN; PRIORITY JOURNAL; PROTEIN FUNCTION; PROTEIN PHOSPHORYLATION; PROTEIN STRUCTURE; STOICHIOMETRY;

ADMINISTRATION, ORAL; ADRENERGIC BETA-ANTAGONISTS; ANIMALS; CARBAZOLES; CARDIAC OUTPUT, LOW; CYCLIC AMP-DEPENDENT PROTEIN KINASES; DOGS; MACROMOLECULAR SUBSTANCES; MATHEMATICS; MYOCARDIUM; PATCH-CLAMP TECHNIQUES; PHOSPHORYLATION; PROPANOLAMINES; RYANODINE RECEPTOR CALCIUM RELEASE CHANNEL; SARCOPLASMIC RETICULUM;

EID: 33846909448     PISSN: 01675273     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ijcard.2006.03.051     Document Type: Article

References (34)

1. Packer M., Bristow M.R., Cohn J.N., and Knecht M. The effect of carvedilol on morbidity and mortality in patients with chronic heart failure. U.S. Carvedilol Heart Failure Study Group N Engl J Med 334 (1996) 1349-1355
2. MERIT-HF. Effect of metoprolol CR/XL in chronic heart failure: metoprolol CR/XL Randomised Intervention Trial in Congestive Heart Failure (MERIT-HF). Lancet 353 (1999) 2001-2007
3. Xue S.R., Zhang X.Y., and Wang J.P. The clinical efficacy of metoprolol for treatment of dilated cardiomyopathy. Chin J Cardiol 28 (2000) 200
4. Braunwald E., and Bristow M.R. Congestive heart failure: fifty years of progress. Circulation 102 suppl IV (2000) IV-14-IV-23
5. Marx S.O., Reiken S., and Hisamatsu Y. PKA phosphorylation dissociates FKBP12.6 from the calcium release channel (ryanodine receptor): defective regulation in failing hearts. Cell 101 (2000) 365-376
6. Marks A.R. Cardiac intracellular calcium release channels: role in heart failure. Circ Res 87 (2000) 8-11
7. Ono K., Yano M., and Ohkusa T. Altered interaction of FKBP12.6 with ryanodine receptor as a cause of abnormal Ca2+ release in heart failure. Cardiovasc Res 48 (2000) 323-331
8. Marx S.O., Reiken S., and Hisamatsu Y. Phosphorylation-dependent regulation of ryanodine receptors: a novel role for leucine/isoleucine zippers. J Cell Biol 153 (2001) 699-708
9. Wang J., Yi G.H., and Knecht M. Physical training alters the pathogenesis of pacing-induced heart failure through endothelium-mediated mechanisms in awake dogs. Circulation 96 (1997) 2683-2692
10. Gilbert E.M., Abraham W.T., and Olsen S. Comparative hemodynamic, left ventricular functional, and antiadrenergic effects of chronic treatment with metoprolol versus carvedilol in the failing heart. Circulation 94 (1996) 2817-2825
11. Nagatsu M., Spinale F.G., and Koide M. Bradycardia and the role of beta-blockade in the amelioration of left ventricular dysfunction. Circulation 101 (2000) 653-659
12. Kaftan E., Marks A.R., and Ehrlich B.E. Effects of rapamycin on ryanodine receptor/Ca2+-release channels from cardiac muscle. Circ Res 78 (1996) 990-997
13. Kiuchi K., Shannon R.P., and Komamura K. Myocardial beta-adrenergic receptor function during the development of pacing-induced heart failure. J Clin Invest 91 (1993) 907-914
14. Dawn B., Xuan Y.T., and Marian M. Cardiac-specific abrogation of NF-NF-κB activation in mice by transdominant express of a mutant IκB-α. J Mol Cell Cardiol 33 (2001) 161-173
15. Neumann J., Eschenhagen T., and Jones LR. Increased expression of cardiac phosphatases in patients with end-stage heart failure. J Mol Cell Cardiol 29 (1997) 265-272
16. Brillantes A.B., Ondrias K., and Scott A. Stabilization of calcium release channel (ryanodine receptor) function by FK506-binding protein. Cell 77 (1994) 513-523
17. Marks A.R. Cellular functions of immunophilins. Physiol Rev 76 (1996) 631-649
18. Marx S.O., Ondrias K., and Marks A.R. Coupled gating between individual skeletal muscle Ca2+ release channels (ryanodine receptors). Science 281 (1998) 818-821
19. Marx S.O., Gaburjakova J., and Gaburjakova M. Coupled gating between cardiac calcium release channels (ryanodine receptors). Circ Res 88 (2001) 1151-1158
20. Eisner D.A., Choi H.S., and Diaz M.E. Integrative analysis of calcium cycling in cardiac muscle. Circ Res 87 (2000) 1087-1094
21. Lehnart S.E., Wehrens X.H.T., and Laitinen P.J. Sudden death in familial polymorphic ventricular tachycardia associated with calcium release channel (ryanodine receptor) leak. Circulation 109 25 (2004) 3208-3214
22. Lehnart S.E., Wehrens X.H.T., and Kushnir A. Cardiac ryanodine receptor function and regulation in heart disease. Ann N Y Acad Sci 1015 1 (2004 (May 1)) 144-159
23. Plank D.M., Yatani A., and Ritsu H. Calcium dynamics in the failing heart: restoration by {beta}-adrenergic receptor blockade. Am J Physiol Heart Circ Physiol 285 1 (2003) H305-H315
24. Reiken S., Wehrens X.H.T., and Vest J.A. {beta}-Blockers restore calcium release channel function and improve cardiac muscle performance in human heart failure. Circulation 107 19 (2003 (May 20)) 2459-2466
25. Doi M., Yano M., and Kobayashi S. Propranolol prevents the development of heart failure by restoring FKBP12.6-mediated stabilization of ryanodine receptor. Circulation 105 11 (2002) 1374-1379
26. Okuda S., Yano M., and Doi M. Valsartan restores sarcoplasmic reticulum function with no appreciable effect on resting cardiac function in pacing-induced heart failure. Circulation 109 7 (2004) 911-919
27. Marks A.R. A guide for the perplexed: towards an understanding of the molecular basis of heart failure. Circulation 107 11 (2003) 1456-1459
28. Scoote M., Poole-Wilson P.A., and Williams A.J. The therapeutic potential of new insights into myocardial excitation-contraction coupling. Heart 89 4 (2003) 371-376
29. Houser S.R., and Margulies K.B. Is depressed myocyte contractility centrally involved in heart failure?. Circ Res 92 4 (2003 (March 7)) 350-358
30. Schmitt J.P., Kamisago M., and Asahi M. Dilated cardiomyopathy and heart failure caused by a mutation in phospholamban. Science 299 5611 (2003) 1410-1413
31. Freedman N.J., and Lefkowitz R.J. Anti-{beta}1-adrenergic receptor antibodies and heart failure: causation, not just correlation. J Clin Invest 113 10 (2004) 1379-1382
32. Yano M., Kobayashi S., and Kohno M. FKBP12.6-mediated stabilization of calcium-release channel (ryanodine receptor) as a novel therapeutic strategy against heart failure. Circulation 107 3 (2003) 477-484
33. Hasenfuss G., and Seidler T. Treatment of heart failure through stabilization of the cardiac ryanodine receptor. Circulation 107 3 (2003) 378-380
34. Marks A.R., Reiken S., and Marx S.O. Progression of heart failure: is protein kinase a hyperphosphorylation of the ryanodine receptor a contributing factor?. Circulation 105 3 (2002) 272-275