Crystal structure of the N-terminal domain of the human protooncogene Nup214/CAN

Proceedings of the National Academy of Sciences of the United States of America

Volumn 104, Issue 6, 2007, Pages 1783-1788

  Napetschnig, Johanna ^a   Blobel, Günter ^a   Hoelz, André ^a  

^a ROCKEFELLER UNIVERSITY   (United States)

Author keywords

propeller; Dbp5 Ddx19; Leukemia; mRNA export; Nuclear pore complex

Indexed keywords

NUCLEOPORIN; RNA HELICASE;

ARTICLE; BINDING AFFINITY; CELL CYCLE; CHROMOSOME TRANSLOCATION; CRYSTAL STRUCTURE; HUMAN; LEUKEMIA; LEUKEMOGENESIS; MOLECULAR DYNAMICS; MOLECULAR INTERACTION; NONHUMAN; NUCLEAR PORE COMPLEX; NUP214 GENE; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN PHOSPHORYLATION; PROTEIN STRUCTURE; PROTO ONCOGENE; STRUCTURE ANALYSIS; YEAST;

AMINO ACID SEQUENCE; CRYSTALLOGRAPHY, X-RAY; HUMANS; MOLECULAR SEQUENCE DATA; NUCLEAR PORE; NUCLEAR PORE COMPLEX PROTEINS; ONCOGENE PROTEINS; PEPTIDE FRAGMENTS; PROTEIN STRUCTURE, TERTIARY; SACCHAROMYCES CEREVISIAE; SACCHAROMYCES CEREVISIAE PROTEINS;

MAMMALIA;

EID: 33846906150     PISSN: 00278424     EISSN: None     Source Type: Journal    
DOI: 10.1073/pnas.0610828104     Document Type: Article

References (36)

1. Rout MP, Aitchison JD, Suprapto A, Hjertaas K, Zhao Y, Chait BT (2000) J Cell Biol 148:635-651.
2. Cronshaw JM, Krutchinsky AN, Zhang W, Chait BT, Matunis MJ (2002) J Cell Biol 158:915-927.
3. Reichelt R, Holzenburg A, Buhle EL, Jr, Jarnik M, Engel A, Aebi U (1990) J Cell Biol 110:883-894.
4. Rout MP, Blobel G (1993) J Cell Biol 123:771-783.
5. Stoffler D, Feja B, Fahrenkrog B, Walz J, Typke D, Aebi U (2003) J Mol Biol 328:119-130.
6. Devos D, Dokudovskaya S, Williams R, Alber F, Eswar N, Chait BT, Rout MP, Sali A (2006) Proc Natl Acad Sci USA 103:2172-2177.
7. Hetzer MW, Walther TC, Mattaj IW (2005) Annu Rev Cell Dev Biol 21:347-380.
8. Kraemer D, Wozniak RW, Blobel G, Radu A (1994) Proc Natl Acad Sci USA 91:1519-1523.
9. von Lindern M, Fornerod M, van Baal S, Jaegle M, de Wit T, Buijs A, Grosveld G (1992) Mol Cell Biol 12:1687-1697.
10. Graux C, Cools J, Melotte C, Quentmeier H, Ferrando A, Levine R, Vermeesch JR, Stul M, Dutta B, Boeckx N, et al. (2004) Nat Genet 36:1084-1089.
11. Fu GK, Grosveld G, Markovitz DM (1997) Proc Natl Acad Sci USA 94:1811-1815.
12. von Lindern M, van Baal S, Wiegant J, Raap A, Hagemeijer A, Grosveld G (1992) Mol Cell Biol 12:3346-3355.
13. Fornerod M, van Deursen J, van Baal S, Reynolds A, Davis D, Murti KG, Fransen J, Grosveld G (1997) EMBO J 16:807-816.
14. Katahira J, Strasser K, Podtelejnikov A, Mann M, Jung JU, Hurt E (1999) EMBO J 18:2593-2609.
15. Suntharalingam M, Wente SR (2003) Dev Cell 4:775-789.
16. Schmitt C, von Kobbe C, Bachi A, Pante N, Rodrigues JP, Boscheron C, Rigaut G, Wilm M, Seraphin B, Carmo-Fonseca M, Izaurralde E (1999) EMBO J 18:4332-4347.
17. Vellieux FM, Huitema F, Groendijk H, Kalk KH, Jzn JF, Jongejan JA, Duine JA, Petratos K, Drenth J, Hol WG (1989) EMBO J 8:2171-2178.
18. Paoli M (2001) Prog Biophys Mol Biol 76:103-130.
19. Wall MA, Coleman DE, Lee E, Iniguez-Lluhi JA, Posner BA, Gilman AG, Sprang SR (1995) Cell 83:1047-1058.
20. Fulop V, Jones DT (1999) Curr Opin Struct Biol 9:715-721.
21. Sondek J, Bohm A, Lambright DG, Hamm HE, Sigler PB (1996) Nature 379:369-374.
22. Appleton BA, Wu P, Wiesmann C (2006) Structure (London) 14:87-96.
23. Gatfield J, Albrecht I, Zanolari B, Steinmetz MO, Pieters J (2005) Mol Biol Cell 16:2786-2798.
24. Beausoleil SA, Jedrychowski M, Schwartz D, Elias JE, Villen J, Li J, Cohn MA, Cantley LC, Gygi SP (2004) Proc Natl Acad Sci USA 101:12130-12135.
25. Weirich CS, Erzberger JP, Berger JM, Weis K (2004) Mol Cell 16:749-760.
26. Cerna D, Wilson DK (2005) J Mol Biol 351:923-935.
27. Berke IC, Boehmer T, Blobel G, Schwartz TU (2004) J Cell Biol 167:591-597.
28. Bastos R, Ribas de Pouplana L, Enarson M, Bodoor K, Burke B (1997) J Cell Biol 137:989-1000.
29. Favreau C, Worman HJ, Wozniak RW, Frappier T, Courvalin JC (1996) Biochemistry 35:8035-8044.
30. Blom N, Gammeltoft S, Brunak S (1999) J Mol Biol 294:1351-1362.
31. Hoelz A, Blobel G (2004) Nature 432:815-816.
32. Hoelz A, Nairn AC, Kuriyan J (2003) Mol Cell 11:1241-1251.
33. de la Fortelle ED, Bricogne G (1997) Methods Enzymol 276:476-494.
34. Collaborative Computational Project No 4 (1994) Acta Crystallogr D 50:760-763.
35. Jones TA, Zou JY, Cowan SW, Kjeldgaard M (1991) Acta Crystallogr A 47:110-119.
36. Brunger AT, Adams PD, Clore, G. M., DeLano WL, Gros P, Grosse-Kunstleve RW, Jiang JS, Kuszewski J, Nilges M, Pannu NS, et al. (1998) Acta Crystallogr D 54:905-921.