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Volumn 17, Issue 4, 2002, Pages 275-283

Ejects of Single and Repeated Treatment with Itraconazole on the Pharmacokinetics of Midazolam in Rats

Author keywords

cytochrome P450; drug interaction; itraconazole; midazolam; pharmacokinetics

Indexed keywords


EID: 33846869033     PISSN: 13474367     EISSN: 18800920     Source Type: Journal    
DOI: 10.2133/dmpk.17.275     Document Type: Article
Times cited : (3)

References (26)
  • 1
    • 0031892244 scopus 로고    scopus 로고
    • Quantitative prediction of the interaction of midazolam and histamine H2 receptor antagonists in rats
    • Takedomi, S., Matsuo, H., Yamano, K., Yamamoto, K., Iga, T. and Sawada, Y.: Quantitative prediction of the interaction of midazolam and histamine H2 receptor antagonists in rats. Drug Metab. Dispos., 26: 318-323 (1998).
    • (1998) Drug Metab. Dispos. , vol.26 , pp. 318-323
    • Takedomi, S.1    Matsuo, H.2    Yamano, K.3    Yamamoto, K.4    Iga, T.5    Sawada, Y.6
  • 2
    • 0032941364 scopus 로고    scopus 로고
    • Quantitative prediction of metabolic inhibition of midazolam by itraconazole and ketoconazole in rats: Implication of concentrative uptake of inhibitors into liver.
    • Yamano, K., Yamamoto, K., Kotaki, H., Sawada, Y. and Iga, T.: Quantitative prediction of metabolic inhibition of midazolam by itraconazole and ketoconazole in rats: Implication of concentrative uptake of inhibitors into liver. Drug Metab. Dispos., 27: 395-402 (1999).
    • (1999) Drug Metab. Dispos. , vol.27 , pp. 395-402
    • Yamano, K.1    Yamamoto, K.2    Kotaki, H.3    Sawada, Y.4    Iga, T.5
  • 3
    • 0035007702 scopus 로고    scopus 로고
    • In-vivo kinetics of the interaction between midazolam and erythromycin in rats, taking account of metabolic intermediate complex formation
    • Takedomi, S., Matsuo, H., Yamano, K., Ohtani, H. and Sawada, Y.: In-vivo kinetics of the interaction between midazolam and erythromycin in rats, taking account of metabolic intermediate complex formation. J. Pharm. Pharmacol., 53: 643-651 (2001).
    • (2001) J. Pharm. Pharmacol , vol.53 , pp. 643-651
    • Takedomi, S.1    Matsuo, H.2    Yamano, K.3    Ohtani, H.4    Sawada, Y.5
  • 5
    • 0033000991 scopus 로고    scopus 로고
    • A reporter gene assay to assess the molecular mechanisms of xenobiotic-dependent induction of the human CYP3A4 gene in vitro
    • Ogg, M. S., Williams, J. M., Tarbit, M., Goldfarb, P. S., Gray, T. J. and Gibson, G. G.: A reporter gene assay to assess the molecular mechanisms of xenobiotic-dependent induction of the human CYP3A4 gene in vitro. Xenobiotica, 29: 269-279 (1999).
    • (1999) Xenobiotica , vol.29 , pp. 269-279
    • Ogg, M.S.1    Williams, J.M.2    Tarbit, M.3    Goldfarb, P.S.4    Gray, T.J.5    Gibson, G.G.6
  • 7
    • 0026595179 scopus 로고
    • Eŝects of imidazole derivatives on cytochromes P450 from human hepatocytes in primary culture
    • Maurice, M., Pichard, L., Daujat, M., Fabre, I., Joyeux, H., Domergue, J. and Maurel, P.: Eŝects of imidazole derivatives on cytochromes P450 from human hepatocytes in primary culture. FASEB J., 6: 752-759 (1992).
    • (1992) FASEB J. , vol.6 , pp. 752-759
    • Maurice, M.1    Pichard, L.2    Daujat, M.3    Fabre, I.4    Joyeux, H.5    Domergue, J.6    Maurel, P.7
  • 9
    • 0026502165 scopus 로고
    • Eŝect of cyclodextrin on the pharmacology of antifungal oral azoles
    • Hostetler, J. N., Hanson, L. H. and Stevens, D. A.: Eŝect of cyclodextrin on the pharmacology of antifungal oral azoles. Antimicrob. Agents Chemother, 36: 477-480 (1992).
    • (1992) Antimicrob. Agents Chemother , vol.36 , pp. 477-480
    • Hostetler, J.N.1    Hanson, L.H.2    Stevens, D.A.3
  • 11
  • 12
    • 0032733974 scopus 로고    scopus 로고
    • Prediction of human clearance of twentynine drugs from hepatic microsomal intrinsic clearance data: an examination of in vitro half-life approach and nonspecîc binding to microsomes
    • Obach, R. S.: Prediction of human clearance of twentynine drugs from hepatic microsomal intrinsic clearance data: an examination of in vitro half-life approach and nonspecîc binding to microsomes. Drug Metabol. Dispos., 27: 1350-1359 (1999).
    • (1999) Drug Metabol. Dispos. , vol.27 , pp. 1350-1359
    • Obach, R.S.1
  • 13
    • 0019854279 scopus 로고
    • A pharmacokinetic analysis program (MULTI) for microcomputer
    • Yamaoka, K., Tanigawara, Y., Nakagawa, T. and Uno, T.: A pharmacokinetic analysis program (MULTI) for microcomputer. J. Pharmacobio-Dyn, 4: 879-885 (1981).
    • (1981) J. Pharmacobio-Dyn , vol.4 , pp. 879-885
    • Yamaoka, K.1    Tanigawara, Y.2    Nakagawa, T.3    Uno, T.4
  • 14
    • 0014949207 scopus 로고
    • Cleavage of structural proteins during the assembly of the head of bacteriophage T4
    • Laemmli, U. K.: Cleavage of structural proteins during the assembly of the head of bacteriophage T4. Nature, 227: 680-685 (1970).
    • (1970) Nature , vol.227 , pp. 680-685
    • Laemmli, U.K.1
  • 15
    • 0028283927 scopus 로고
    • Carrier-mediated active transport of histamine H2 receptor antagonist. Cimetidine and nizatidine, into isolated rat hepatocytes: contribution of type I system
    • Nakamura, H., Sano, H., Yamazaki, M. and Sugiyama, Y.: Carrier-mediated active transport of histamine H2 receptor antagonist. Cimetidine and nizatidine, into isolated rat hepatocytes: contribution of type I system. J. Pharmacol. Exp. Ther., 269: 1220-1227 (1994).
    • (1994) J. Pharmacol. Exp. Ther , vol.269 , pp. 1220-1227
    • Nakamura, H.1    Sano, H.2    Yamazaki, M.3    Sugiyama, Y.4
  • 16
    • 0029926676 scopus 로고    scopus 로고
    • Recent advances in carrier-mediated hepatic uptake and biliary excretion of xenobiotics
    • Yamazaki, M., Suzuki, H. and Sugiyama, Y.: Recent advances in carrier-mediated hepatic uptake and biliary excretion of xenobiotics. Pharm. Res., 13: 497-513 (1996).
    • (1996) Pharm. Res. , vol.13 , pp. 497-513
    • Yamazaki, M.1    Suzuki, H.2    Sugiyama, Y.3
  • 17
    • 0032755435 scopus 로고    scopus 로고
    • Correlation between in vivo and in vitro hepatic uptake of metabolic inhibitors of cytochrome P-450 in rats
    • Yamano, K., Yamamoto, K., Kotaki, H., Takedomi, S., Matsuo, H., Sawada, Y. and Iga, T.: Correlation between in vivo and in vitro hepatic uptake of metabolic inhibitors of cytochrome P-450 in rats. Drug Metab. Dispos., 27: 1225-1231 (1999).
    • (1999) Drug Metab. Dispos. , vol.27 , pp. 1225-1231
    • Yamano, K.1    Yamamoto, K.2    Kotaki, H.3    Takedomi, S.4    Matsuo, H.5    Sawada, Y.6    Iga, T.7
  • 18
    • 0034059924 scopus 로고    scopus 로고
    • Quantitative prediction of metabolic inhibition of midazolam by erythromycin, diltiazem, verapamil in rats: implication of concentrative uptake of inhibitors into liver
    • Yamano, K., Yamamoto, K., Kotaki, H., Takedomi, S., Matsuo, H., Sawada, Y. and Iga, T.: Quantitative prediction of metabolic inhibition of midazolam by erythromycin, diltiazem, and verapamil in rats: implication of concentrative uptake of inhibitors into liver. J. Pharmacol. Exp. Ther., 292: 1118-1126 (2000).
    • (2000) J. Pharmacol. Exp. Ther , vol.292 , pp. 1118-1126
    • Yamano, K.1    Yamamoto, K.2    Kotaki, H.3    Takedomi, S.4    Matsuo, H.5    Sawada, Y.6    Iga, T.7
  • 20
    • 0034089555 scopus 로고    scopus 로고
    • Prediction of in vivo interaction between triazolam and erythromycin based on in vitro studies using human liver microsomes and recombinant human CYP3A4
    • Kanamitsu, S., Ito, K., Green, C. E., Tyson, C. A., Shimada, N. and Sugiyama, Y.: Prediction of in vivo interaction between triazolam and erythromycin based on in vitro studies using human liver microsomes and recombinant human CYP3A4. Pharm. Res., 17: 419-426 (2000).
    • (2000) Pharm. Res. , vol.17 , pp. 419-426
    • Kanamitsu, S.1    Ito, K.2    Green, C.E.3    Tyson, C.A.4    Shimada, N.5    Sugiyama, Y.6
  • 21
    • 0004062227 scopus 로고    scopus 로고
    • Cytochrome P450 3A degradation in isolated rat hepatocytes: 26S proteasome inhibitors as probes
    • Wang, H. F., Figueiredopereira, M. E. and Correia, M. A.: Cytochrome P450 3A degradation in isolated rat hepatocytes: 26S proteasome inhibitors as probes. Arch. Biochem. Ciophys., 365: 45-53 (1999).
    • (1999) Arch. Biochem. Ciophys. , vol.365 , pp. 45-53
    • Wang, H.F.1    Figueiredopereira, M.E.2    Correia, M.A.3
  • 22
    • 0030986960 scopus 로고    scopus 로고
    • Evidence of proteasome-mediated cytochrome P-450 degradation
    • Robert, B. J.: Evidence of proteasome-mediated cytochrome P-450 degradation. J. Biol. Chem., 272: 9771-9778 (1997).
    • (1997) J. Biol. Chem , vol.272 , pp. 9771-9778
    • Robert, B.J.1
  • 23
    • 0026989765 scopus 로고
    • Degradation of rat liver cytochromes P450 3A after their inactivation by 3, 5-dicarbethoxy-2, 6-dimethyl-4-ethyl-1, 4-dihydropyridine: Characterization of the proteolytic system
    • Correia, M. A., Davoll, S. H., Wrighton, S. A. and Thomas, P. E.: Degradation of rat liver cytochromes P450 3A after their inactivation by 3, 5-dicarbethoxy-2, 6-dimethyl-4-ethyl-1, 4-dihydropyridine: Characterization of the proteolytic system. Arch. Biochem. Biophys., 297: 228-238 (1992).
    • (1992) Arch. Biochem. Biophys. , vol.297 , pp. 228-238
    • Correia, M.A.1    Davoll, S.H.2    Wrighton, S.A.3    Thomas, P.E.4
  • 24
    • 0033054009 scopus 로고    scopus 로고
    • In-vivo and in-vitro metabolic clearance of midazolam, a cytochrome P450 3A substrate, by the liver under normal and increased enzyme activity in rats
    • Higashikawa, F., Murakami, T., Kaneda, T. and Takano, M.: In-vivo and in-vitro metabolic clearance of midazolam, a cytochrome P450 3A substrate, by the liver under normal and increased enzyme activity in rats. J. Pharm. Pharmacol., 51: 405-10 (1999).
    • (1999) J. Pharm. Pharmacol , vol.51 , pp. 405-410
    • Higashikawa, F.1    Murakami, T.2    Kaneda, T.3    Takano, M.4
  • 25
    • 0033045179 scopus 로고    scopus 로고
    • Activation of human cytochrome P-450 3A4-catalyzed meloxicam 5?-methylhydroxylation by quinidine and hydroquinidine in vitro
    • Ludwig, E., Schmidt, J., Beschke, K. and Ebner, T.: Activation of human cytochrome P-450 3A4-catalyzed meloxicam 5?-methylhydroxylation by quinidine and hydroquinidine in vitro. J. Pharmacol. Exp. Ther., 290: 1-8 (1999).
    • (1999) J. Pharmacol. Exp. Ther , vol.290 , pp. 1-8
    • Ludwig, E.1    Schmidt, J.2    Beschke, K.3    Ebner, T.4
  • 26
    • 0032859247 scopus 로고    scopus 로고
    • Midazolam alpha-hydroxylation by human liver microsomes in vitro: inhibition by calcium channel blockers, itraconazole and ketoconazole
    • Wang, J. S., Wen, X., Backman, J. T., Taavitsainen, P., Neuvonen, P. J. and Kivisto, K. T.: Midazolam alpha-hydroxylation by human liver microsomes in vitro: inhibition by calcium channel blockers, itraconazole and ketoconazole. Pharmacol. Toxicol., 85: 157-161 (1999).)
    • (1999) Pharmacol. Toxicol. , vol.85 , pp. 157-161
    • Wang, J.S.1    Wen, X.2    Backman, J.T.3    Taavitsainen, P.4    Neuvonen, P.J.5    Kivisto, K.T.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.