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Volumn 85, Issue 4, 1999, Pages 157-161

Midazolam α-hydroxylation by human liver microsomes in vitro: Inhibition by calcium channel blockers, itraconazole and ketoconazole

Author keywords

[No Author keywords available]

Indexed keywords

CALCIUM CHANNEL BLOCKING AGENT; CYTOCHROME; DILTIAZEM; HYDROXYITRACONAZOLE; ISRADIPINE; ITRACONAZOLE; KETOCONAZOLE; MIBEFRADIL; MIDAZOLAM; NIFEDIPINE; VERAPAMIL;

EID: 0032859247     PISSN: 09019928     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1600-0773.1999.tb00085.x     Document Type: Article
Times cited : (59)

References (32)
  • 1
    • 0025949455 scopus 로고
    • Comparative effects of the antimycotic drugs ketoconazole, fluconazole, itraconazole and terbinafine on the metabolism of cyclosporin by human liver microsomes
    • Back, D. J. & J. F. Tjia: Comparative effects of the antimycotic drugs ketoconazole, fluconazole, itraconazole and terbinafine on the metabolism of cyclosporin by human liver microsomes. Brit. J. Clin. Pharmacol. 1991, 32, 624-626.
    • (1991) Brit. J. Clin. Pharmacol. , vol.32 , pp. 624-626
    • Back, D.J.1    Tjia, J.F.2
  • 3
    • 0003037045 scopus 로고
    • Prediction of inhibitory drug-drug interactions by studies in vitro
    • Eds.: G. M. Pacifici & G. N. Fracchia. Office for Official Publications or the European Communities, Luxembourg
    • Boobis, A. R.: Prediction of inhibitory drug-drug interactions by studies in vitro. In: Advances in drug metabolism in man. Eds.: G. M. Pacifici & G. N. Fracchia. Office for Official Publications or the European Communities, Luxembourg, 1995, pp. 515-539.
    • (1995) Advances in Drug Metabolism in Man , pp. 515-539
    • Boobis, A.R.1
  • 4
    • 0030430033 scopus 로고    scopus 로고
    • Cytochrome P450 isoform inhibitors as a tool for the investigation of metabolic reactions catalyzed by human liver microsomes
    • Bourrie, M., V. Meunier, Y. Berger & G. Fabre: Cytochrome P450 isoform inhibitors as a tool for the investigation of metabolic reactions catalyzed by human liver microsomes. J. Pharmacol. Exp. Therap. 1996, 277, 321-332.
    • (1996) J. Pharmacol. Exp. Therap. , vol.277 , pp. 321-332
    • Bourrie, M.1    Meunier, V.2    Berger, Y.3    Fabre, G.4
  • 5
    • 0025841871 scopus 로고
    • Lack of effect of the calcium antagonist isradipine on cyclosporine pharmacokinetics in renal transplant patients
    • Endresen, L., S. Bergan, H. Holdaas, T. Pran, B. Sinding-Larsen & K. J. Berg: Lack of effect of the calcium antagonist isradipine on cyclosporine pharmacokinetics in renal transplant patients. Ther. Drug Monit. 1991, 13, 490-495.
    • (1991) Ther. Drug Monit. , vol.13 , pp. 490-495
    • Endresen, L.1    Bergan, S.2    Holdaas, H.3    Pran, T.4    Sinding-Larsen, B.5    Berg, K.J.6
  • 6
    • 0025999285 scopus 로고
    • In vitro forecasting of drugs which may interfere with the biotransformation of midazolam
    • Gascon, M.-P. & P. Dayer: In vitro forecasting of drugs which may interfere with the biotransformation of midazolam. Eur. J. Clin. Pharmacol. 1991, 41, 573-578.
    • (1991) Eur. J. Clin. Pharmacol. , vol.41 , pp. 573-578
    • Gascon, M.-P.1    Dayer, P.2
  • 7
    • 0028234586 scopus 로고
    • Regioselective biotransformation of midazolam by members of the human cytochrome P450 3A (CYP3A) subfamily
    • Gorski, J. C., S. D. Hall, D. R. Jones, M. Vanden Branden & S. A. Wrighton: Regioselective biotransformation of midazolam by members of the human cytochrome P450 3A (CYP3A) subfamily. Biochem. Pharmacol. 1994, 47, 1643-1653.
    • (1994) Biochem. Pharmacol. , vol.47 , pp. 1643-1653
    • Gorski, J.C.1    Hall, S.D.2    Jones, D.R.3    Vanden Branden, M.4    Wrighton, S.A.5
  • 8
    • 0027244966 scopus 로고
    • Determination of midazolam and its α-hydroxy metabolite inhuman plasma and urine by high-performance liquid chromatography
    • Ha, H. R., K. M. Rentsch, J. Kneer & D. J. Vonderschmitt: Determination of midazolam and its α-hydroxy metabolite inhuman plasma and urine by high-performance liquid chromatography. Ther. Drug Monit. 1993, 15, 338-343.
    • (1993) Ther. Drug Monit. , vol.15 , pp. 338-343
    • Ha, H.R.1    Rentsch, K.M.2    Kneer, J.3    Vonderschmitt, D.J.4
  • 10
    • 0024422554 scopus 로고
    • Pharmacokinetics of diltiazem and its metabolites after repeated multiple-dose treatments in healthy volunteers
    • Höglund, P. & L.-G. Nilsson: Pharmacokinetics of diltiazem and its metabolites after repeated multiple-dose treatments in healthy volunteers. Ther. Drug Monit. 1989, 11, 543-550.
    • (1989) Ther. Drug Monit. , vol.11 , pp. 543-550
    • Höglund, P.1    Nilsson, L.-G.2
  • 11
    • 0030882158 scopus 로고    scopus 로고
    • Plasma buspirone concentrations are greatly increased by erythromycin and itraconazole
    • Kivistö, K. T., T. S. Lamberg, T. Kantola & P. J. Neuvonen: Plasma buspirone concentrations are greatly increased by erythromycin and itraconazole. Clin. Pharmacol. Therap. 1997, 62, 348-354.
    • (1997) Clin. Pharmacol. Therap. , vol.62 , pp. 348-354
    • Kivistö, K.T.1    Lamberg, T.S.2    Kantola, T.3    Neuvonen, P.J.4
  • 12
    • 0023114637 scopus 로고
    • Nifedipine. Relationship between pharmacokinetics and pharmacodynamics
    • Kleinbloesem, C. H., P. van Brummelen & D. D. Breimer: Nifedipine. Relationship between pharmacokinetics and pharmacodynamics. Clin. Pharmacokin. 1987, 12, 12-29.
    • (1987) Clin. Pharmacokin. , vol.12 , pp. 12-29
    • Kleinbloesem, C.H.1    Van Brummelen, P.2    Breimer, D.D.3
  • 14
    • 0024373348 scopus 로고
    • Oxidation of midazolam and triazolam by human liver cytochrome P450IIIA4
    • Kronbach, T., D. Mathys, M. Umeno, F. J. Gonzalez & U. A. Meyer: Oxidation of midazolam and triazolam by human liver cytochrome P450IIIA4. Mol. Pharmacol. 1989, 36, 89-96.
    • (1989) Mol. Pharmacol. , vol.36 , pp. 89-96
    • Kronbach, T.1    Mathys, D.2    Umeno, M.3    Gonzalez, F.J.4    Meyer, U.A.5
  • 15
    • 0031844932 scopus 로고    scopus 로고
    • Effects of verapamil and diltiazem on the pharmacokinetics and pharmacodynamics of buspirone
    • Lamberg, T. S., K. T. Kivistö & P. J. Neuvonen: Effects of verapamil and diltiazem on the pharmacokinetics and pharmacodynamics of buspirone. Clin. Pharmacol. Therap. 1998, 63, 640-645.
    • (1998) Clin. Pharmacol. Therap. , vol.63 , pp. 640-645
    • Lamberg, T.S.1    Kivistö, K.T.2    Neuvonen, P.J.3
  • 16
    • 0031955337 scopus 로고    scopus 로고
    • Cytochrome P450 specificity of metabolism and interactions of oxybutynin in human liver microsomes
    • Lukkari, E., P. Taavitsainen, A. Juhakoski & O. Pelkonen: Cytochrome P450 specificity of metabolism and interactions of oxybutynin in human liver microsomes. Pharmacology & Toxicology 1998, 82, 161-166.
    • (1998) Pharmacology & Toxicology , vol.82 , pp. 161-166
    • Lukkari, E.1    Taavitsainen, P.2    Juhakoski, A.3    Pelkonen, O.4
  • 17
    • 0026611310 scopus 로고
    • Pharmacokinetic-pharmacodynamic modeling of the central nervous system effects of midazolam and its main metabolite alpha-hydroxymidazolam in healthy volunteers
    • Mandema, J. W., B. Tuk, A. L. van Steveninck, D. D. Breimer, A. F. Cohen & M. Danhof: Pharmacokinetic-pharmacodynamic modeling of the central nervous system effects of midazolam and its main metabolite alpha-hydroxymidazolam in healthy volunteers. Clin. Pharmacol. Therap. 1992, 51, 715-728.
    • (1992) Clin. Pharmacol. Therap. , vol.51 , pp. 715-728
    • Mandema, J.W.1    Tuk, B.2    Van Steveninck, A.L.3    Breimer, D.D.4    Cohen, A.F.5    Danhof, M.6
  • 18
    • 0028357256 scopus 로고
    • Midazolam should be avoided in patients receiving the systemic antimycotics ketoconazole or itraconazole
    • Olkkola, K. T., J. T. Backman & P. J. Neuvonen: Midazolam should be avoided in patients receiving the systemic antimycotics ketoconazole or itraconazole. Clin. Pharmacol. Therap. 1994, 55, 481-485.
    • (1994) Clin. Pharmacol. Therap. , vol.55 , pp. 481-485
    • Olkkola, K.T.1    Backman, J.T.2    Neuvonen, P.J.3
  • 20
    • 0032551211 scopus 로고    scopus 로고
    • What lessons can be learnt from withdrawal of mibefradil from the market?
    • Po, A. L. & W. Y. Zhang: What lessons can be learnt from withdrawal of mibefradil from the market? Lancet 1998, 351, 1829-1830.
    • (1998) Lancet , vol.351 , pp. 1829-1830
    • Po, A.L.1    Zhang, W.Y.2
  • 21
    • 0026050581 scopus 로고
    • Pharmacokinetic interactions with calcium channel antagonists (Part II)
    • Schlanz, K. D., S. A. Myre & M. B. Bottorff: Pharmacokinetic interactions with calcium channel antagonists (Part II). Clin. Pharmacokin. 1991, 21, 448-460.
    • (1991) Clin. Pharmacokin. , vol.21 , pp. 448-460
    • Schlanz, K.D.1    Myre, S.A.2    Bottorff, M.B.3
  • 23
    • 0030875423 scopus 로고    scopus 로고
    • Role of CYP3A4 in human hepatic diltiazem N-demethylation: Inhibition of CYP3A4 activity by oxidized diltiazem metabolites
    • Sutton, D., A. M. Butler, L. Nadin & M. Murray: Role of CYP3A4 in human hepatic diltiazem N-demethylation: inhibition of CYP3A4 activity by oxidized diltiazem metabolites. J. Pharmacol. Exp. Therap. 1997, 282, 294-300.
    • (1997) J. Pharmacol. Exp. Therap. , vol.282 , pp. 294-300
    • Sutton, D.1    Butler, A.M.2    Nadin, L.3    Murray, M.4
  • 25
    • 0025236599 scopus 로고
    • Metabolite inhibition of parent drug biotransformation. Studies of diltiazem
    • Tsao, S. C., T. H. Dickinson & D. R. Abernethy: Metabolite inhibition of parent drug biotransformation. Studies of diltiazem. Drug Metab. Dispos. 1990, 18, 180-183.
    • (1990) Drug Metab. Dispos. , vol.18 , pp. 180-183
    • Tsao, S.C.1    Dickinson, T.H.2    Abernethy, D.R.3
  • 26
    • 0023245523 scopus 로고
    • Pharmacokinetics of PN 200-110 (isradipine), a new calcium antagonist, after oral administration in man
    • Tse, F. L. S. & J. M. Jaffe: Pharmacokinetics of PN 200-110 (isradipine), a new calcium antagonist, after oral administration in man. Eur. J. Clin. Pharmacol. 1987, 32, 361-365.
    • (1987) Eur. J. Clin. Pharmacol. , vol.32 , pp. 361-365
    • Tse, F.L.S.1    Jaffe, J.M.2
  • 27
    • 0028568243 scopus 로고
    • Oral triazolam is potentially hazardous to patients receiving systemic antimycotics ketoconazole or itraconazole
    • Varhe, A., K. T. Olkkola & P. J. Neuvonen: Oral triazolam is potentially hazardous to patients receiving systemic antimycotics ketoconazole or itraconazole. Clin Pharmacol. Therap. 1994, 56, 601-607.
    • (1994) Clin Pharmacol. Therap. , vol.56 , pp. 601-607
    • Varhe, A.1    Olkkola, K.T.2    Neuvonen, P.J.3
  • 28
    • 0029925714 scopus 로고    scopus 로고
    • Diltiazem enhances the effects of triazolam by inhibiting its metabolism
    • Varhe, A., K. T. Olkkola & P. J. Neuvonen: Diltiazem enhances the effects of triazolam by inhibiting its metabolism. Clin. Pharmacol. Therap. 1996, 59, 369-375.
    • (1996) Clin. Pharmacol. Therap. , vol.59 , pp. 369-375
    • Varhe, A.1    Olkkola, K.T.2    Neuvonen, P.J.3
  • 30
    • 0029743080 scopus 로고    scopus 로고
    • Midazolam hydroxylation by human fiver microsomes in vitro: Inhibition by fluoxetine, norfluoxetine, and by azole antifungal agents
    • von Moltke, L. L., D. J. Greenblatt, J. Schmider, S. X. Duan, C. E. Wright, J. S. Harmatz & R. I. Shader: Midazolam hydroxylation by human fiver microsomes in vitro: inhibition by fluoxetine, norfluoxetine, and by azole antifungal agents. J. Clin. Pharmacol. 1996, 36, 783-791.
    • (1996) J. Clin. Pharmacol. , vol.36 , pp. 783-791
    • Von Moltke, L.L.1    Greenblatt, D.J.2    Schmider, J.3    Duan, S.X.4    Wright, C.E.5    Harmatz, J.S.6    Shader, R.I.7
  • 32
    • 0028361593 scopus 로고
    • Inhibition of human CYP3A catalyzed 1′-hydroxy midazolam formation by ketoconazole, nifedipine, crythromycin, cimetidine, and nizatidine
    • Wrighton, S. A. & B. J. Ring: Inhibition of human CYP3A catalyzed 1′-hydroxy midazolam formation by ketoconazole, nifedipine, crythromycin, cimetidine, and nizatidine. Pharm. Res. 1994, 11, 921-924.
    • (1994) Pharm. Res. , vol.11 , pp. 921-924
    • Wrighton, S.A.1    Ring, B.J.2


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