NKG2D-mediated cytotoxicity toward oligodendrocytes suggests a mechanism for tissue injury in multiple sclerosis

Journal of Neuroscience

Volumn 27, Issue 5, 2007, Pages 1220-1228

  Saikali, Philippe ^a   Antel, Jack P ^a   Newcombe, Jia ^c   Chen, Zhihong ^d   Freedman, Mark ^d   Blain, Manon ^a   Cayrol, Romain ^e   Prat, Alexandre ^e   Hall, Jeffery A ^b   Arbour, Nathalie ^a,e  

^a MCGILL UNIVERSITY   (Canada)

^b MCGILL UNIVERSITY   (Canada)

^c UNIVERSITY COLLEGE LONDON   (United Kingdom)

^d UNIVERSITY OF OTTAWA   (Canada)

^e CENTRE HOSPITALIER DE L UNIVERSITÉ DE MONTRÉAL   (Canada)

Author keywords

Astrocytes; Autoimmunity; Human; Lymphocytes; Multiple sclerosis; Oligodendrocytes

Indexed keywords

BLOCKING ANTIBODY; NATURAL KILLER CELL RECEPTOR NKG2D;

ALLOIMMUNITY; ARTICLE; ASTROCYTE; CD8+ T LYMPHOCYTE; CELL ACTIVATION; CELL KILLING; COLON POLYPOSIS; CONTROLLED STUDY; CYTOTOXICITY; EMBRYO; GLIA CELL; HUMAN; HUMAN CELL; IMMUNE RESPONSE; IN VITRO STUDY; MICROGLIA; MULTIPLE SCLEROSIS; NATURAL KILLER CELL; NERVE CELL; OLIGODENDROGLIA; PRIORITY JOURNAL; TISSUE INJURY; WHITE MATTER;

EID: 33846829507     PISSN: 02706474     EISSN: 02706474     Source Type: Journal    
DOI: 10.1523/JNEUROSCI.4402-06.2007     Document Type: Article

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