메뉴 건너뛰기




Volumn 13, Issue 3, 1997, Pages 141-153

Synthetic hispidin, a PKC inhibitor, is more cytotoxic toward cancer cells than normal cells in vitro

Author keywords

anti neoplastic drug; cancer; hispidin; keratinocyte; protein kinase C

Indexed keywords

HISPIDIN; PROTEIN KINASE C; PROTEIN KINASE C INHIBITOR; UNCLASSIFIED DRUG;

EID: 0030959893     PISSN: 07422091     EISSN: None     Source Type: Journal    
DOI: 10.1023/A:1007321227010     Document Type: Article
Times cited : (94)

References (43)
  • 1
    • 0025916220 scopus 로고
    • Mechanism of colchicine binding to tubulin. Tolerance of substituents in ring-C′ of biphenyl analogs
    • Andreu JM, Gorbunoff MJ, Medrano FJ, Rossi M, Timasheff SN. Mechanism of colchicine binding to tubulin. Tolerance of substituents in ring-C′ of biphenyl analogs. Biochemistry. 1991;30:3777-86.
    • (1991) Biochemistry. , vol.30 , pp. 3777-3786
    • Andreu, J.M.1    Gorbunoff, M.J.2    Medrano, F.J.3    Rossi, M.4    Timasheff, S.N.5
  • 2
    • 0019810961 scopus 로고
    • An update on the biochemistry of 5-fluorouracil
    • Ardalan B, Glazer R. An update on the biochemistry of 5-fluorouracil. Cancer Treat Rev. 1981;8:157-67.
    • (1981) Cancer Treat Rev , vol.8 , pp. 157-167
    • Ardalan, B.1    Glazer, R.2
  • 3
    • 0026456849 scopus 로고
    • Regulation of phospholipid hydrolysis and 2nd messenger formation by protein kinase C
    • Bishop WR, Pachter JA, Pai JK. Regulation of phospholipid hydrolysis and 2nd messenger formation by protein kinase C. Adv Enzyme Regul. 1992;32:177-92.
    • (1992) Adv Enzyme Regul , vol.32 , pp. 177-192
    • Bishop, W.R.1    Pachter, J.A.2    Pai, J.K.3
  • 4
    • 0015990773 scopus 로고
    • Adriamycin: A new anti-cancer drug with significant clinical activity
    • Blum RH, Carter SK. Adriamycin: a new anti-cancer drug with significant clinical activity. Ann Int Med. 1974;80:249-59.
    • (1974) Ann Int Med , vol.80 , pp. 249-259
    • Blum, R.H.1    Carter, S.K.2
  • 5
    • 0141434860 scopus 로고
    • Protein kinase C directly phosphorylates the insulin receptor in vitro and reduces its protein-tyrosine kinase activity
    • Bollag GE, Roth RA, Beaudoin J, Mochly-Rosen D, Koshland DE. Protein kinase C directly phosphorylates the insulin receptor in vitro and reduces its protein-tyrosine kinase activity. Proc Natl Acad Sci USA. 1986;83:5822-4.
    • (1986) Proc Natl Acad Sci USA , vol.83 , pp. 5822-5824
    • Bollag, G.E.1    Roth, R.A.2    Beaudoin, J.3    Mochly-Rosen, D.4    Koshland, D.E.5
  • 6
    • 0020084137 scopus 로고
    • Phenotypic and genotypic characteristics of a cell line from a squamous cell carcinoma of human skin
    • Boukamp P, Tilgen W, Dzarlieva RT et al. Phenotypic and genotypic characteristics of a cell line from a squamous cell carcinoma of human skin. J Natl Cancer Inst. 1982;68:415-22.
    • (1982) J Natl Cancer Inst , vol.68 , pp. 415-422
    • Boukamp, P.1    Tilgen, W.2    Dzarlieva, R.T.3
  • 7
    • 0022373473 scopus 로고
    • Environmental modulation of the expression of differentiation and malignancy in six human squamous cell carcinoma cell lines
    • Boukamp P, Rupniak TR, Fusenig NE. Environmental modulation of the expression of differentiation and malignancy in six human squamous cell carcinoma cell lines. Cancer Res. 1985;45:5582-92.
    • (1985) Cancer Res , vol.45 , pp. 5582-5592
    • Boukamp, P.1    Rupniak, T.R.2    Fusenig, N.E.3
  • 9
    • 0015332686 scopus 로고
    • The physiological disposition of 5-fluorouracil in mice bearing solid L1210 lymphocytic leukemia
    • Chadwich M, Rogers WI. The physiological disposition of 5-fluorouracil in mice bearing solid L1210 lymphocytic leukemia. Cancer Res. 1972;32:1045-56.
    • (1972) Cancer Res , vol.32 , pp. 1045-1056
    • Chadwich, M.1    Rogers, W.I.2
  • 10
    • 0020546053 scopus 로고
    • Differential sensitivity of pancreatic adenocarcinoma cell lines to chemotherapeutic agents in culture
    • Chang BK. Differential sensitivity of pancreatic adenocarcinoma cell lines to chemotherapeutic agents in culture. Cancer Treat Rev. 1983;67:355-61.
    • (1983) Cancer Treat Rev. , vol.67 , pp. 355-361
    • Chang, B.K.1
  • 11
    • 0018373594 scopus 로고
    • Binding of cis-and trans-dichlorodiammineplatinum (II) to DNA: Evidence for unwinding and shortening of the double helix
    • Cohen GL, Bauer WR, Barton JK, Lippard SJ. Binding of cis-and trans-dichlorodiammineplatinum (II) to DNA: evidence for unwinding and shortening of the double helix. Science. 1979;203:1014-6.
    • (1979) Science , vol.203 , pp. 1014-1016
    • Cohen, G.L.1    Bauer, W.R.2    Barton, J.K.3    Lippard, S.J.4
  • 12
    • 0028484480 scopus 로고
    • The discovery of protein phosphatases: From chaos and confusion to an understanding of their role in cell regulation and human disease
    • Cohen P. The discovery of protein phosphatases: from chaos and confusion to an understanding of their role in cell regulation and human disease. Bioassays. 1994; 16:583-8.
    • (1994) Bioassays , vol.16 , pp. 583-588
    • Cohen, P.1
  • 13
    • 0027319626 scopus 로고
    • Protein kinase C activates chloride conductance in C127 cells stably expressing the cystic fibrosis gene
    • Dechecchi MC, Tamanini A, Berton G, Cabrini G. Protein kinase C activates chloride conductance in C127 cells stably expressing the cystic fibrosis gene. J Biol Chem. 1993;268: 11321-5.
    • (1993) J Biol Chem , vol.268 , pp. 11321-11325
    • Dechecchi, M.C.1    Tamanini, A.2    Berton, G.3    Cabrini, G.4
  • 14
    • 37049045208 scopus 로고
    • Constituents of the higher fungi. Part II. the synthesis of hispidin
    • Edwards RL, Wilson DV. Constituents of the higher fungi. Part II. The synthesis of hispidin. J Chem Soc. 1961;4:5003-4.
    • (1961) J Chem Soc , vol.4 , pp. 5003-5004
    • Edwards, R.L.1    Wilson, D.V.2
  • 15
    • 37049041604 scopus 로고
    • Constituents of the higher fungi. Part I. Hispidin, a new 4-hydroxy-6-styryl-2-pyrone from Polyporus hispidus
    • Edwards RL, Lewis DG, Wilson DV. Constituents of the higher fungi. Part I. Hispidin, a new 4-hydroxy-6-styryl-2-pyrone from Polyporus hispidus. J Chem Soc. 1961;4:4995-5002.
    • (1961) J Chem Soc , vol.4 , pp. 4995-5002
    • Edwards, R.L.1    Lewis, D.G.2    Wilson, D.V.3
  • 16
    • 0017412603 scopus 로고
    • One hundred and twenty-seven cultured human tumor cell lines producing tumors in nude mice
    • Fögh J, Fogh JM, Orfeo T. One hundred and twenty-seven cultured human tumor cell lines producing tumors in nude mice. J Natl Cancer Inst. 1977;59:221-6.
    • (1977) J Natl Cancer Inst , vol.59 , pp. 221-226
    • Fögh, J.1    Fogh, J.M.2    Orfeo, T.3
  • 17
    • 0027366699 scopus 로고
    • Reciprocal effects on the protein kinase C inhibitors staurosporine and H-7 on the regulation of glycol synthetase and phosphorases in the primary culture of hepatocytes
    • Gali RR, Pugazhenthi S, Chandelier RL. Reciprocal effects on the protein kinase C inhibitors staurosporine and H-7 on the regulation of glycol synthetase and phosphorases in the primary culture of hepatocytes. Metab Clin Exp. 1993;42: 1475-80.
    • (1993) Metab Clin Exp , vol.42 , pp. 1475-1480
    • Gali, R.R.1    Pugazhenthi, S.2    Chandelier, R.L.3
  • 18
    • 0025338014 scopus 로고
    • Involvement of protein kinase-C in the regulation of assembly-disassembly of neurofilaments in vitro
    • Gonda Y, Nishizawa K, Ando S et al. Involvement of protein kinase-C in the regulation of assembly-disassembly of neurofilaments in vitro. Biochem Biophys Res Commun. 1990;167:1316-25.
    • (1990) Biochem Biophys Res Commun , vol.167 , pp. 1316-1325
    • Gonda, Y.1    Nishizawa, K.2    Ando, S.3
  • 19
    • 0023897154 scopus 로고
    • Differential effects of flavonoids as inhibitors of tyrosine protein kinases and serine/threonine protein kinases
    • Hagiwara M, Inoue S, Tanaka T, Nunoki K, Ito M, Hikada H. Differential effects of flavonoids as inhibitors of tyrosine protein kinases and serine/threonine protein kinases. Biochem Pharmacol. 1988;37:2987-92.
    • (1988) Biochem Pharmacol , vol.37 , pp. 2987-2992
    • Hagiwara, M.1    Inoue, S.2    Tanaka, T.3    Nunoki, K.4    Ito, M.5    Hikada, H.6
  • 20
    • 0000875305 scopus 로고
    • Studies on fluorinated pyrimidines. XIII. Inhibition of thymidylate synthetase
    • Hartmann KU, Heidelberger C. Studies on fluorinated pyrimidines. XIII. Inhibition of thymidylate synthetase. J Biol Chem. 1961;236:3006-13.
    • (1961) J Biol Chem , vol.236 , pp. 3006-3013
    • Hartmann, K.U.1    Heidelberger, C.2
  • 21
    • 0025676633 scopus 로고
    • Calcium phosphate deposits in domes of human pancreatic adenocarcinoma (Capan-1) cell cultures
    • Hollande E, Levrat Di Donato JH et al. Calcium phosphate deposits in domes of human pancreatic adenocarcinoma (Capan-1) cell cultures. Bio Cell. 1990;69:191-203.
    • (1990) Bio Cell , vol.69 , pp. 191-203
    • Hollande, E.1    Levrat Di Donato, J.H.2
  • 22
    • 0020540151 scopus 로고
    • The protein phosphatases involved in cellular regulation. I. Classification and substrate specificities
    • Ingebritsen TS, Cohen P. The protein phosphatases involved in cellular regulation. I. Classification and substrate specificities. Eur J Biochem. 1983;132:255-61.
    • (1983) Eur J Biochem , vol.132 , pp. 255-261
    • Ingebritsen, T.S.1    Cohen, P.2
  • 23
    • 0014941518 scopus 로고
    • Characteristics of a human diploid cell designated MRC-5
    • Jacobs JP, Jones CM, Baille JP. Characteristics of a human diploid cell designated MRC-5. Nature. 1970;227:168-70.
    • (1970) Nature , vol.227 , pp. 168-170
    • Jacobs, J.P.1    Jones, C.M.2    Baille, J.P.3
  • 24
    • 0025302762 scopus 로고
    • Synthesis and biological evaluation of 2-styrylquinazolin-4 (3H)-ones, a new class of antimitotic anticancer agents which inhibit tubulin polymerization
    • Jiang JB, Hesson DP, Dusak BA, Dexter DL, Kang GH, Hamel E. Synthesis and biological evaluation of 2-styrylquinazolin-4 (3H)-ones, a new class of antimitotic anticancer agents which inhibit tubulin polymerization. J Med Chem. 1990;33:1721-8.
    • (1990) J Med Chem , vol.33 , pp. 1721-1728
    • Jiang, J.B.1    Hesson, D.P.2    Dusak, B.A.3    Dexter, D.L.4    Kang, G.H.5    Hamel, E.6
  • 25
    • 0020060077 scopus 로고
    • Human pancreatic adenocarcinoma cell line Capan-1 in tissue culture and the nude mouse. Morphologic, biologic and biochemical characteristics
    • Kyriazis AP, Kyriazis AA, Scarpelli DG, Fögh J, Rao MS, Lepera R. Human pancreatic adenocarcinoma cell line Capan-1 in tissue culture and the nude mouse. Morphologic, biologic and biochemical characteristics. Am J Pathol. 1982;106:250-60.
    • (1982) Am J Pathol , vol.106 , pp. 250-260
    • Kyriazis, A.P.1    Kyriazis, A.A.2    Scarpelli, D.G.3    Fögh, J.4    Rao, M.S.5    Lepera, R.6
  • 26
    • 0028000069 scopus 로고
    • Signal-transduction therapy. A novel approach to disease management
    • Levitzki A. Signal-transduction therapy. A novel approach to disease management. Eur J Biochem. 1994;226:1-13.
    • (1994) Eur J Biochem , vol.226 , pp. 1-13
    • Levitzki, A.1
  • 28
    • 0028574131 scopus 로고
    • The expression of carbonic anhydrases II and IV in the human pancreatic cancer cell line (Capan-1) is associated with bicarbonate ion channels
    • Mahieu I, Becq F, Wolfensberger T, Gola M, Carter N, Hollande E. The expression of carbonic anhydrases II and IV in the human pancreatic cancer cell line (Capan-1) is associated with bicarbonate ion channels. Biol Cell. 1994; 81:131-41.
    • (1994) Biol Cell , vol.81 , pp. 131-141
    • Mahieu, I.1    Becq, F.2    Wolfensberger, T.3    Gola, M.4    Carter, N.5    Hollande, E.6
  • 30
    • 0018098683 scopus 로고
    • Differential inhibition of the products of the human alkaline phosphatase loci
    • Mullivor RA, Plutkin LI, Harris H. Differential inhibition of the products of the human alkaline phosphatase loci. Ann Hum Genet. 1978;42:1-13.
    • (1978) Ann Hum Genet , vol.42 , pp. 1-13
    • Mullivor, R.A.1    Plutkin, L.I.2    Harris, H.3
  • 31
    • 0023764824 scopus 로고
    • The molecular heterogeneity of protein kinase C and its implications for cellular regulation
    • Nishizuka Y. The molecular heterogeneity of protein kinase C and its implications for cellular regulation. Nature. 1988; 334:661-5.
    • (1988) Nature , vol.334 , pp. 661-665
    • Nishizuka, Y.1
  • 32
    • 0029060391 scopus 로고
    • Protein kinase C and lipid signaling for sustained cellular responses
    • Nishizuka Y. Protein kinase C and lipid signaling for sustained cellular responses. FASEB J. 1995;9:484-96.
    • (1995) FASEB J , vol.9 , pp. 484-496
    • Nishizuka, Y.1
  • 33
    • 0028114192 scopus 로고
    • Introduction: Protein kinases
    • Pawson T. Introduction: protein kinases. FASEB J. 1994;8: 1112-3.
    • (1994) FASEB J , vol.8 , pp. 1112-1113
    • Pawson, T.1
  • 34
    • 0026063670 scopus 로고
    • Design of potent protein kinase inhibitors using the bisubstrate approach
    • Ricouart A, Gesquiere JC, Tartar A, Sergheraert C. Design of potent protein kinase inhibitors using the bisubstrate approach. J Med Chem. 1991;34:73-8.
    • (1991) J Med Chem , vol.34 , pp. 73-78
    • Ricouart, A.1    Gesquiere, J.C.2    Tartar, A.3    Sergheraert, C.4
  • 35
    • 0015493364 scopus 로고
    • Cross-linking of complementary strands of DNA in mammalian cells by antitumour platinum compounds
    • Roberts JJ, Pascoe JM. Cross-linking of complementary strands of DNA in mammalian cells by antitumour platinum compounds. Nature. 1972;235:282-4.
    • (1972) Nature , vol.235 , pp. 282-284
    • Roberts, J.J.1    Pascoe, J.M.2
  • 36
    • 0014691619 scopus 로고
    • Platinum compounds: A new class of potent antitumor agents
    • Rosenberg B, Van Camp L, Trosko JE, Mansour VH. Platinum compounds: a new class of potent antitumor agents. Nature. 1969;222:385-6.
    • (1969) Nature , vol.222 , pp. 385-386
    • Rosenberg, B.1    Van Camp, L.2    Trosko, J.E.3    Mansour, V.H.4
  • 37
    • 0025193302 scopus 로고
    • 2 synthesis in human amnion by protein kinase-C
    • 2 synthesis in human amnion by protein kinase-C. Prostaglandins. 1990; 39:355-63.
    • (1990) Prostaglandins , vol.39 , pp. 355-363
    • Sander, J.1    Myatt, L.2
  • 38
    • 0026558326 scopus 로고
    • Mechanism of inhibition of microtubule polymerization by colchicine: Inhibitory potencies of unliganded colchicine and tubulin-colchicine complexes
    • Skoufias DA, Wilson L. Mechanism of inhibition of microtubule polymerization by colchicine: inhibitory potencies of unliganded colchicine and tubulin-colchicine complexes. Biochemistry. 1992;31:738-46.
    • (1992) Biochemistry , vol.31 , pp. 738-746
    • Skoufias, D.A.1    Wilson, L.2
  • 40
    • 0025267465 scopus 로고
    • Enzymatic studies of the effect of Cu (II) on oxygen radical production stimulated by daunorubicin and ametantrone
    • Tarasiuk J, Kolodziejczyk P, Borowski E. Enzymatic studies of the effect of Cu (II) on oxygen radical production stimulated by daunorubicin and ametantrone. Biochem Pharmacol. 1990;39:1405-10.
    • (1990) Biochem Pharmacol , vol.39 , pp. 1405-1410
    • Tarasiuk, J.1    Kolodziejczyk, P.2    Borowski, E.3
  • 41
    • 0028557441 scopus 로고
    • Multiple pathway signal transduction by the cAMP-dependent protein kinase
    • Walsh DA, Van Patten SM. Multiple pathway signal transduction by the cAMP-dependent protein kinase. FASEB J. 1994;8:1227-36.
    • (1994) FASEB J , vol.8 , pp. 1227-1236
    • Walsh, D.A.1    Van Patten, S.M.2
  • 43
    • 0028218540 scopus 로고
    • New mechanism of action of the cancer chemotherapeutic agent 5-fluorouracil in human cells
    • Wurzer JC, Tallarida RJ, Sirover MA. New mechanism of action of the cancer chemotherapeutic agent 5-fluorouracil in human cells. J Pharmacol Exp Ther. 1994;269:39-43.
    • (1994) J Pharmacol Exp Ther , vol.269 , pp. 39-43
    • Wurzer, J.C.1    Tallarida, R.J.2    Sirover, M.A.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.