-
1
-
-
0032569028
-
KID-1, a protein kinase induced by depolarization in brain
-
Feldman JD, Vician L, Crispino M et al. KID-1, a protein kinase induced by depolarization in brain. J Biol Chem 1998; 273: 16535-43.
-
(1998)
J Biol Chem
, vol.273
, pp. 16535-16543
-
-
Feldman, J.D.1
Vician, L.2
Crispino, M.3
-
2
-
-
0033564628
-
Pim kinase expression is induced by LTP stimulation and required for the consolidation of enduring LTP
-
Konietzko U, Kauselmann G, Scafidi J et al. Pim kinase expression is induced by LTP stimulation and required for the consolidation of enduring LTP. EMBO J 1999; 18: 3359-69.
-
(1999)
EMBO J
, vol.18
, pp. 3359-3369
-
-
Konietzko, U.1
Kauselmann, G.2
Scafidi, J.3
-
3
-
-
0024595556
-
Predisposition to lymphomagenesis in pim-1 transgenic mice: Cooperation with c- myc and N- myc in murine leukemia-virus-induced tumors
-
van Lohuizen M, Verbeek S, Krimpenfort P et al. Predisposition to lymphomagenesis in pim-1 transgenic mice: Cooperation with c- myc and N- myc in murine leukemia-virus-induced tumors. Cell 1989; 56: 673-82.
-
(1989)
Cell
, vol.56
, pp. 673-682
-
-
van Lohuizen, M.1
Verbeek, S.2
Krimpenfort, P.3
-
4
-
-
0025986962
-
Eμ N- and Eμ 1-myc cooperate with Eμ pim-1 to generate lymphoid tumors at high frequency in double transgenic mice
-
Moroy T, Verbeek S, Ma A, Achacoso P, Berns A, Alt F. Eμ N- and Eμ 1-myc cooperate with Eμ pim-1 to generate lymphoid tumors at high frequency in double transgenic mice. Oncogene 1991; 6: 1941-8.
-
(1991)
Oncogene
, vol.6
, pp. 1941-1948
-
-
Moroy, T.1
Verbeek, S.2
Ma, A.3
Achacoso, P.4
Berns, A.5
Alt, F.6
-
5
-
-
0030829781
-
Pim-2 transgene induces lymphoid tumors, exhibiting potent synergy with c-myc
-
Allen JD, Verhoeven E, Domen J, van der Valk M, Berns A. Pim-2 transgene induces lymphoid tumors, exhibiting potent synergy with c-myc. Oncogene 1997; 15: 1133-41.
-
(1997)
Oncogene
, vol.15
, pp. 1133-1141
-
-
Allen, J.D.1
Verhoeven, E.2
Domen, J.3
van der Valk, M.4
Berns, A.5
-
6
-
-
24144458232
-
Pim family kinases enhance tumor growth of prostate cancer cells
-
Chen WW, Chan DC, Donald C, Lilly MB, Kraft AS. Pim family kinases enhance tumor growth of prostate cancer cells. Mol Cancer Res 2005; 3: 443-51.
-
(2005)
Mol Cancer Res
, vol.3
, pp. 443-451
-
-
Chen, W.W.1
Chan, D.C.2
Donald, C.3
Lilly, M.B.4
Kraft, A.S.5
-
7
-
-
0037569709
-
PIM3 proto-oncogene kinase is a common transcriptional target of divergent EWS/ETS oncoproteins
-
Deneen B, Welford SM, Ho T, Hernandez F, Kurland I, Denny CT. PIM3 proto-oncogene kinase is a common transcriptional target of divergent EWS/ETS oncoproteins. Mol Cell Biol 2003; 23: 3897-908.
-
(2003)
Mol Cell Biol
, vol.23
, pp. 3897-3908
-
-
Deneen, B.1
Welford, S.M.2
Ho, T.3
Hernandez, F.4
Kurland, I.5
Denny, C.T.6
-
8
-
-
13244284663
-
Aberrant expression of serine/threonine kinase Pim-3 in hepatocellular carcinoma development and its role in the proliferation of human hepatoma cell lines
-
Fujii C, Nakamoto Y, Lu P et al. Aberrant expression of serine/threonine kinase Pim-3 in hepatocellular carcinoma development and its role in the proliferation of human hepatoma cell lines. Int J Cancer 2005; 114: 209-18.
-
(2005)
Int J Cancer
, vol.114
, pp. 209-218
-
-
Fujii, C.1
Nakamoto, Y.2
Lu, P.3
-
9
-
-
33746122005
-
Pim-3, a proto-oncogene with serine/threonine kinase activity, is aberrantly expressed in human pancreatic cancer and phosphorylates Bad to block Bad-mediated apoptosis in human pancreatic cancer cell lines
-
Li Y-Y, Popivanova BK, Nagai Y, Ishikura H, Fujii C, Mukaida N. Pim-3, a proto-oncogene with serine/threonine kinase activity, is aberrantly expressed in human pancreatic cancer and phosphorylates Bad to block Bad-mediated apoptosis in human pancreatic cancer cell lines. Cancer Res 2006; 66: 6741-7.
-
(2006)
Cancer Res
, vol.66
, pp. 6741-6747
-
-
Li, Y.-Y.1
Popivanova, B.K.2
Nagai, Y.3
Ishikura, H.4
Fujii, C.5
Mukaida, N.6
-
10
-
-
0028589378
-
Regulation of cell number in the mammalian gastrointestinal tract: The importance of apoptosis
-
Hall PA, Coates PJ, Ansari B, Hopwood D. Regulation of cell number in the mammalian gastrointestinal tract: The importance of apoptosis. J Cell Sci 1994; 107: 3569-77.
-
(1994)
J Cell Sci
, vol.107
, pp. 3569-3577
-
-
Hall, P.A.1
Coates, P.J.2
Ansari, B.3
Hopwood, D.4
-
11
-
-
0030592517
-
Lessons from hereditary colorectal cancer
-
Kinzler KW, Vogelstein B. Lessons from hereditary colorectal cancer. Cell 1996; 87: 159-70.
-
(1996)
Cell
, vol.87
, pp. 159-170
-
-
Kinzler, K.W.1
Vogelstein, B.2
-
13
-
-
0028941441
-
Inhibition of apoptosis during development of colorectal cancer
-
Bedi A, Pasricha PJ, Akhtar AJ et.al. Inhibition of apoptosis during development of colorectal cancer. Cancer Res 1995; 55: 1811-6.
-
(1995)
Cancer Res
, vol.55
, pp. 1811-1816
-
-
Bedi, A.1
Pasricha, P.J.2
Akhtar, A.J.3
-
14
-
-
26444448463
-
The survival kinases Akt and Pim as potential pharmacological targets
-
Amaravadi R, Thompson CB. The survival kinases Akt and Pim as potential pharmacological targets. J Clin Invest 2005; 115: 2618-24.
-
(2005)
J Clin Invest
, vol.115
, pp. 2618-2624
-
-
Amaravadi, R.1
Thompson, C.B.2
-
15
-
-
0242580961
-
The PIM-2 kinase phosphorylates Bad on serine 112 and reverses Bad-induced cell death
-
Yan B, Zemskova M, Holder S et al. The PIM-2 kinase phosphorylates Bad on serine 112 and reverses Bad-induced cell death. J Biol Chem 2003; 278: 45358-67.
-
(2003)
J Biol Chem
, vol.278
, pp. 45358-45367
-
-
Yan, B.1
Zemskova, M.2
Holder, S.3
-
16
-
-
3343007095
-
Pim-1 kinase promotes inactivation of the pro-apoptotic Bad protein by phosphorylating it on the Ser 112 gatekeeper site
-
Aho TLT, Sandholm J, Peltola K, Mankonen HP, Lilly M, Koskinen PJ. Pim-1 kinase promotes inactivation of the pro-apoptotic Bad protein by phosphorylating it on the Ser 112 gatekeeper site. FEBS Lett 2004; 571: 43-9.
-
(2004)
FEBS Lett
, vol.571
, pp. 43-49
-
-
Aho, T.L.T.1
Sandholm, J.2
Peltola, K.3
Mankonen, H.P.4
Lilly, M.5
Koskinen, P.J.6
-
17
-
-
0017102107
-
Classification of human colorectal adenocarcinoma cell lines
-
Leibovitz A, Stinson JC, McCombs 3rd WB, McCoy CE, Mazur KC, Mabry ND. Classification of human colorectal adenocarcinoma cell lines. Cancer Res 1976; 36: 4562-9.
-
(1976)
Cancer Res
, vol.36
, pp. 4562-4569
-
-
Leibovitz, A.1
Stinson, J.C.2
McCombs III, W.B.3
McCoy, C.E.4
Mazur, K.C.5
Mabry, N.D.6
-
18
-
-
0017405580
-
Markers of neoplastic transformation in epithelial cell lines derived from human carcinomas
-
Marshall CJ, Franks LM, Carbonell AW. Markers of neoplastic transformation in epithelial cell lines derived from human carcinomas. J Natl Cancer Inst 1977; 58: 1743-51.
-
(1977)
J Natl Cancer Inst
, vol.58
, pp. 1743-1751
-
-
Marshall, C.J.1
Franks, L.M.2
Carbonell, A.W.3
-
19
-
-
0019804468
-
Initiation and characterization of cultures of human colonic carcinoma with different biological characteristics utilizing feeder layers of confluent fibroblasts
-
Brattain MG, Brattain DE, Fine WD et al. Initiation and characterization of cultures of human colonic carcinoma with different biological characteristics utilizing feeder layers of confluent fibroblasts. Oncol Dev Biol Med 1981; 2: 355-9.
-
(1981)
Oncol Dev Biol Med
, vol.2
, pp. 355-359
-
-
Brattain, M.G.1
Brattain, D.E.2
Fine, W.D.3
-
20
-
-
0033537768
-
2+-induced apoptosis through calcineutin dephosphorylation of Bad
-
2+-induced apoptosis through calcineutin dephosphorylation of Bad. Science 1999; 284: 339-43.
-
(1999)
Science
, vol.284
, pp. 339-343
-
-
Wang, H.G.1
Pathan, N.2
Ethell, I.M.3
-
21
-
-
0026446343
-
Prevention of protein denaturation under heat stress by the chaperonin Hsp60
-
Martin J, Horwich AL, Hartl FU. Prevention of protein denaturation under heat stress by the chaperonin Hsp60. Science 1992; 258: 995-8.
-
(1992)
Science
, vol.258
, pp. 995-998
-
-
Martin, J.1
Horwich, A.L.2
Hartl, F.U.3
-
22
-
-
0037311538
-
Sulindac sulfide inhibits epidermal growth factor-induced phosphorylation of extracellular-regulated kinase 1/2 and Bad in human colon cancer cells
-
Rice PL, Washington M, Schleman S, Beard KS, Driggers LJ, Ahnen DJ. Sulindac sulfide inhibits epidermal growth factor-induced phosphorylation of extracellular-regulated kinase 1/2 and Bad in human colon cancer cells. Cancer Res 2003; 63: 616-20.
-
(2003)
Cancer Res
, vol.63
, pp. 616-620
-
-
Rice, P.L.1
Washington, M.2
Schleman, S.3
Beard, K.S.4
Driggers, L.J.5
Ahnen, D.J.6
-
23
-
-
13944257829
-
Selective inhibitors of MEK1/ERK 44/42 and p38 mitogen-activated protein kinases potentiate apoptosis induction by sulindac sulfide in human colon carcinoma cells
-
Sun Y, Sinicrope FA. Selective inhibitors of MEK1/ERK 44/42 and p38 mitogen-activated protein kinases potentiate apoptosis induction by sulindac sulfide in human colon carcinoma cells. Mol Cancer Ther 2005; 4: 51-9.
-
(2005)
Mol Cancer Ther
, vol.4
, pp. 51-59
-
-
Sun, Y.1
Sinicrope, F.A.2
-
24
-
-
23844521568
-
The protein kinase Cβ-selective inhibitor, enzastaurin (LY317615.HCI), suppresses signaling through the Akt pathway, induces apoptosis, and suppresses growth of human colon cancer and glioblastoma xenografts
-
Graff JR, McNulty AM, Hanna KR et al. The protein kinase Cβ-selective inhibitor, enzastaurin (LY317615.HCI), suppresses signaling through the Akt pathway, induces apoptosis, and suppresses growth of human colon cancer and glioblastoma xenografts. Cancer Res 2005; 65: 7462-9.
-
(2005)
Cancer Res
, vol.65
, pp. 7462-7469
-
-
Graff, J.R.1
McNulty, A.M.2
Hanna, K.R.3
-
25
-
-
0036195196
-
Akt proto-oncogene overexpression is an early event during sporadic colon carcinogenesis
-
Roy HK, Olusola BF, Clemens DL et al. Akt proto-oncogene overexpression is an early event during sporadic colon carcinogenesis. Carcinogenesis 2002; 23: 201-5.
-
(2002)
Carcinogenesis
, vol.23
, pp. 201-205
-
-
Roy, H.K.1
Olusola, B.F.2
Clemens, D.L.3
-
26
-
-
0037096804
-
Phosphorylation of Akt/PKB is required for suppression of cancer cell apoptosis and tumor progression in human colorectal carcinoma
-
Itoh N, Semba S, Ito M, Takeda H, Kawata S, Yamakawa M. Phosphorylation of Akt/PKB is required for suppression of cancer cell apoptosis and tumor progression in human colorectal carcinoma. Cancer 2002; 94: 3127-34.
-
(2002)
Cancer
, vol.94
, pp. 3127-3134
-
-
Itoh, N.1
Semba, S.2
Ito, M.3
Takeda, H.4
Kawata, S.5
Yamakawa, M.6
-
27
-
-
20044379405
-
Structural basis of constitutive activity and a unique nucleotide binding mode of human Pim-1 kinase
-
Qian KC, Wang L, Hickey ER et al. Structural basis of constitutive activity and a unique nucleotide binding mode of human Pim-1 kinase. J Biol Chem 2005; 280: 6130-7.
-
(2005)
J Biol Chem
, vol.280
, pp. 6130-6137
-
-
Qian, K.C.1
Wang, L.2
Hickey, E.R.3
-
28
-
-
33644860129
-
Genome-wide differences between microsatellite stable and unstable colorectal tumors
-
Camps J, Armengol G, Del Rey J et al. Genome-wide differences between microsatellite stable and unstable colorectal tumors. Carcinogenesis 2006; 27: 419-28.
-
(2006)
Carcinogenesis
, vol.27
, pp. 419-428
-
-
Camps, J.1
Armengol, G.2
Del Rey, J.3
-
29
-
-
26244463218
-
Constitutive activation of JAK3/STAT3 in colon carcinoma tumors and cell lines
-
Lin Q, Lai R, Chirieac LR et al. Constitutive activation of JAK3/STAT3 in colon carcinoma tumors and cell lines. Am J Pathol 2005; 167: 969-80.
-
(2005)
Am J Pathol
, vol.167
, pp. 969-980
-
-
Lin, Q.1
Lai, R.2
Chirieac, L.R.3
-
30
-
-
11244255857
-
Implication of STAT3 signaling in human colonic cancer cells during intestinal trefoil factor 3 (TFF3) -and vascular endothelial growth factor-mediated cellular invasion and tumor growth
-
Rivat C, Rodrigues S, Bryuneel E et al. Implication of STAT3 signaling in human colonic cancer cells during intestinal trefoil factor 3 (TFF3) -and vascular endothelial growth factor-mediated cellular invasion and tumor growth. Cancer Res 2005; 65: 195-202.
-
(2005)
Cancer Res
, vol.65
, pp. 195-202
-
-
Rivat, C.1
Rodrigues, S.2
Bryuneel, E.3
-
31
-
-
5644252874
-
TGF-β suppresses tumor progression in colon cancer by inhibition of IL-6 trans -signaling
-
Becker C, Fantini MC, Schramm C et al. TGF-β suppresses tumor progression in colon cancer by inhibition of IL-6 trans -signaling. Immunity 2004; 21: 491-501.
-
(2004)
Immunity
, vol.21
, pp. 491-501
-
-
Becker, C.1
Fantini, M.C.2
Schramm, C.3
-
32
-
-
0033451992
-
Synergistic roles for Pim-1 and c-Myc in STAT3-mediated cell cycle progression and antiapoptosis
-
Shirogane T, Fukada T, Muller JMM, Shima DT, Hibi M, Hirano T. Synergistic roles for Pim-1 and c-Myc in STAT3-mediated cell cycle progression and antiapoptosis. immunity 1999; 11: 709-19.
-
(1999)
Immunity
, vol.11
, pp. 709-719
-
-
Shirogane, T.1
Fukada, T.2
Muller, J.M.M.3
Shima, D.T.4
Hibi, M.5
Hirano, T.6
-
33
-
-
0033560095
-
Interferon-α activates multiple STAT proteins and upregulates proliferation-associated IL-2Rα, c-myc, and Pim-1 genes in human T cells
-
Matikainen S, Sareneva T, Ronni T, Lehtonen A, Koskinen PJ, Julkunen I. Interferon-α activates multiple STAT proteins and upregulates proliferation-associated IL-2Rα, c-myc, and Pim-1 genes in human T cells. Blood 1999; 93: 1980-91.
-
(1999)
Blood
, vol.93
, pp. 1980-1991
-
-
Matikainen, S.1
Sareneva, T.2
Ronni, T.3
Lehtonen, A.4
Koskinen, P.J.5
Julkunen, I.6
-
34
-
-
4344657971
-
Inactivating mutations of proapoptotic Bad gene in human colon cancers
-
Lee JW, Soung YH, Kim SY et al. Inactivating mutations of proapoptotic Bad gene in human colon cancers. Carcinogenesis 2004; 25: 1371-6.
-
(2004)
Carcinogenesis
, vol.25
, pp. 1371-1376
-
-
Lee, J.W.1
Soung, Y.H.2
Kim, S.Y.3
-
35
-
-
0028809209
-
Bad, a heterodimeric partner for Bcl-X L and Bcl-2, displaces Bax and promotes cell death
-
Yang E, Zha J, Jockel J, Boise LH, Thompson CB, Korsmeyer SJ. Bad, a heterodimeric partner for Bcl-X L and Bcl-2, displaces Bax and promotes cell death. Cell 1995; 80: 285-91.
-
(1995)
Cell
, vol.80
, pp. 285-291
-
-
Yang, E.1
Zha, J.2
Jockel, J.3
Boise, L.H.4
Thompson, C.B.5
Korsmeyer, S.J.6
-
36
-
-
19944432123
-
Differential targeting of prosurvival Bcl-2 proteins by their BH3-only ligands allows complementary apoptotic function
-
Chen L, Willis SN, Wei A et al. Differential targeting of prosurvival Bcl-2 proteins by their BH3-only ligands allows complementary apoptotic function. Mol Cell 2005; 17: 393-403.
-
(2005)
Mol Cell
, vol.17
, pp. 393-403
-
-
Chen, L.1
Willis, S.N.2
Wei, A.3
-
37
-
-
0030695837
-
Bad is a BH3 domain-containing protein that forms an inactivating dimmer with Bcl-X L
-
Kelekar A, Chang BS, Harlan J, Fesik SW, Thompson CB. Bad is a BH3 domain-containing protein that forms an inactivating dimmer with Bcl-X L. Mol Cell Biol 1997; 17: 7040-6.
-
(1997)
Mol Cell Biol
, vol.17
, pp. 7040-7046
-
-
Kelekar, A.1
Chang, B.S.2
Harlan, J.3
Fesik, S.W.4
Thompson, C.B.5
-
38
-
-
0030584088
-
Serine phosphorylation of death agonist Bad in response to survival factor results in binding to 14-3-3 not BCL-X L
-
Zha J, Harada H, Yang E, Jockel J, Korsmeyer SJ. Serine phosphorylation of death agonist Bad in response to survival factor results in binding to 14-3-3 not BCL-X L. Cell 1996; 87: 619-28.
-
(1996)
Cell
, vol.87
, pp. 619-628
-
-
Zha, J.1
Harada, H.2
Yang, E.3
Jockel, J.4
Korsmeyer, S.J.5
-
39
-
-
0030702123
-
Akt phosphorylation of Bad couples survival signals to the cell-intrinsic death machinery
-
Datta SR, Dudek H, Tao X et al. Akt phosphorylation of Bad couples survival signals to the cell-intrinsic death machinery. Cell 1997; 91: 231-41.
-
(1997)
Cell
, vol.91
, pp. 231-241
-
-
Datta, S.R.1
Dudek, H.2
Tao, X.3
-
41
-
-
0035872442
-
Inhibition of signal transduction by Hsp90 inhibitor 17-allylamino-17-demethoxygeldanamycin results in cytostasis and apoptosis
-
Hostein I, Robertson D, DiStefano F, Workman P, Clarke PA. Inhibition of signal transduction by Hsp90 inhibitor 17-allylamino-17-demethoxygeldanamycin results in cytostasis and apoptosis. Cancer Res 2001; 61: 4003-9.
-
(2001)
Cancer Res
, vol.61
, pp. 4003-4009
-
-
Hostein, I.1
Robertson, D.2
DiStefano, F.3
Workman, P.4
Clarke, P.A.5
|