The novel atypical retinoid ST1926 is active in ATRA resistant neuroblastoma cells acting by a different mechanism

Biochemical Pharmacology

Volumn 73, Issue 5, 2007, Pages 643-655

  Di Francesco, Angela Maria ^a   Meco, Daniela ^a   Torella, Anna Rita ^a   Barone, Giuseppe ^a   D'Incalci, Maurizio ^b   Pisano, Claudio ^c   Carminati, Paolo ^c   Riccardi, Riccardo ^a  

^a CATHOLIC UNIVERSITY   (Italy)

^b MARIO NEGRI INSTITUTE FOR PHARMACOLOGICAL RESEARCH   (Italy)

^c Research and Development   (Italy)

Author keywords

Alkaline Comet assay; Apoptosis; Atypical retinoids; DNA damage; Neuroblastoma; ST1926

Indexed keywords

3 [3' (1 ADAMANTYL) 4' HYDROXYBIPHENYL 4 YL]ACRYLIC ACID; 6 [3 (1 ADAMANTYL) 4 HYDROXYPHENYL] 2 NAPHTHOIC ACID; BENZYLOXYCARBONYLVALYLALANYLASPARTYL FLUOROMETHYL KETONE; CASPASE; CASPASE INHIBITOR; PROTEIN P53; RETINOIC ACID; RETINOID DERIVATIVE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; CANCER CELL CULTURE; CANCER INHIBITION; CELL CYCLE ARREST; CELL CYCLE G2 PHASE; CELL CYCLE S PHASE; CELL DIFFERENTIATION; CELL STRUCTURE; CONTROLLED STUDY; CYTOTOXICITY; DNA DAMAGE; DRUG TOLERABILITY; HUMAN; HUMAN CELL; MALE; MOUSE; NEUROBLASTOMA; NEUROBLASTOMA CELL; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; XENOGRAFT;

ADAMANTANE; ANIMALS; ANTINEOPLASTIC AGENTS; CELL CYCLE; CELL LINE, TUMOR; CINNAMATES; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG ADMINISTRATION SCHEDULE; DRUG RESISTANCE, NEOPLASM; HUMANS; MALE; MICE; MICE, NUDE; MOLECULAR STRUCTURE; NEUROBLASTOMA; TRETINOIN;

EID: 33846594384     PISSN: 00062952     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bcp.2006.10.033     Document Type: Article

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