Evidence supporting a role for mitochondrial respiration in apoptosis induction by the synthetic retinoid CD437

Cancer Research

Volumn 61, Issue 18, 2001, Pages 6698-6702

  Hail N , Jr ^a   Youssef, E M ^a   Lotan, R ^a  

^a UNIVERSITY OF TEXAS MD ANDERSON CANCER CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

6 [3 (1 ADAMANTYL) 4 HYDROXYPHENYL] 2 NAPHTHOIC ACID; RETINOIC ACID; RETINOID;

APOPTOSIS; ARTICLE; CANCER CELL CULTURE; CANCER RESISTANCE; CASE REPORT; CONTROLLED STUDY; DRUG MECHANISM; FEMALE; HUMAN; HUMAN CELL; MEMBRANE PERMEABILITY; MITOCHONDRIAL MEMBRANE; MITOCHONDRIAL RESPIRATION; PRIORITY JOURNAL; SKIN CARCINOMA; SQUAMOUS CELL CARCINOMA;

ANTINEOPLASTIC AGENTS; APOPTOSIS; CARCINOMA, SQUAMOUS CELL; CLONE CELLS; DRUG RESISTANCE, NEOPLASM; FEMALE; HUMANS; INTRACELLULAR MEMBRANES; MEMBRANE POTENTIALS; MITOCHONDRIA; OXYGEN CONSUMPTION; RETINOIDS; SKIN NEOPLASMS; TUMOR CELLS, CULTURED;

EID: 0035884594     PISSN: 00085472     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (24)

1. Rapid induction of apoptosis in human C33A cervical carcinoma cells by the synthetic retinoid 6-[3-(1-adamantyl)hydroxyphenyl]-2-naphtalene carboxylic acid (CD437)
2. Retinoid induced apoptosis in leukemia cells through a retinoic acid nuclear receptor-independent pathway
3. The novel retinoid 6-[3-(1-adamantyl)-4-hydroxyphenyl]-2-naphtalene carboxylic acid can trigger apoptosis through a mitochondrial pathway independent of the nucleus
4. Induction of apoptosis in human non-small cell lung carcinoma cells by the novel synthetic retinoid CD437
5. 1 arrest in their normal counterparts
6. Mitochondria as regulators of apoptosis: Doubt no more
7. Mitochondria and apoptosis
8. Mitochondrion as a novel target of anticancer chemotherapy
9. Aberrant mitochondria in two human colon carcinoma cell lines
10. Hydroperoxide metabolism in mammalian organs
11. Superoxide production by the mitochondrial respiratory chain
12. A human squamous cell carcinoma cell line
13. Isolation of human cell lines lacking mitochondrial DNA
14. Simultaneous increase of mitochondrial DNA deletions and lipid peroxidation in human aging
15. Mitochondrial respiratory control and the polarographic measurement of ADP/O ratios
16. The mitochondrial permeability transition
17. Mitochondrial permeability transition is a central coordinating event in N-(4-hydroxyphenly)retinamide-induced apoptosis
18. Analytical and numerical techniques for evaluation of free radical damage in cultured cells using imaging cytometry and fluorescent indicators
19. Inhibitors of NADH-ubiquinone reductase: An overview
20. Hydrophobic sites of the mitochondrial electron transfer system
21. Biology of free radical scavengers: An evaluation of ascorbate
22. Progress on the mitochondrial permeability transition pore: Regulation by complex I and ubiquinone analogs
23. 0 cells
24. Aerobic glycolysis by proliferating cells: Protection against oxidative stress at the expense of energy yield