Protein kinase A exhibits selective modulation of estradiol-dependent transcription in breast cancer cells that is associated with decreased ligand binding, altered estrogen receptor α promoter interaction, and changes in receptor phosphorylation

Molecular Endocrinology

Volumn 21, Issue 2, 2007, Pages 439-456

  Al Dhaheri, Mariam H ^a   Rowan, Brian G ^a,b  

^a MEDICAL COLLEGE OF OHIO   (United States)

^b TULANE UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CYCLIC AMP; CYCLIC AMP DEPENDENT PROTEIN KINASE; CYCLIN D1; ESTRADIOL; ESTROGEN RECEPTOR ALPHA; FORSKOLIN; FULVESTRANT; HEAT SHOCK PROTEIN 90; HYDROXYTAMOXIFEN; ISOBUTYLMETHYLXANTHINE; SERINE; TAMOXIFEN;

ARTICLE; BREAST CANCER; CANCER INHIBITION; CELL PROLIFERATION; CHROMATIN IMMUNOPRECIPITATION; CONTROLLED STUDY; DRUG INHIBITION; DRUG MECHANISM; ENZYME ACTIVITY; ENZYME INHIBITION; GENE CONTROL; GENETIC TRANSCRIPTION; HORMONE ACTION; HORMONE BINDING; HORMONE RECEPTOR INTERACTION; HUMAN; HUMAN CELL; LIGAND BINDING; PRIORITY JOURNAL; PROTEIN INTERACTION; PROTEIN PHOSPHORYLATION; PROTEIN PROTEIN INTERACTION; REPORTER GENE; TRANSCRIPTION REGULATION;

1-METHYL-3-ISOBUTYLXANTHINE; BREAST NEOPLASMS; CELL LINE, TUMOR; CELL PROLIFERATION; CYCLIC AMP; CYCLIC AMP-DEPENDENT PROTEIN KINASES; CYCLIN D1; ESTRADIOL; ESTROGEN RECEPTOR ALPHA; FEMALE; FORSKOLIN; GENE EXPRESSION REGULATION, NEOPLASTIC; HSP90 HEAT-SHOCK PROTEINS; HUMANS; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS; LIGANDS; PHOSPHORYLATION; PROMOTER REGIONS (GENETICS); SIGNAL TRANSDUCTION; TAMOXIFEN; TRANSCRIPTION, GENETIC;

EID: 33846568011     PISSN: 08888809     EISSN: None     Source Type: Journal    
DOI: 10.1210/me.2006-0059     Document Type: Article

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