Selective estrogen receptor modulator regulated proteins in endometrial cancer cells

Molecular and Cellular Endocrinology

Volumn 219, Issue 1-2, 2004, Pages 127-139

  Shah, Yatrik M ^a   Basrur, Venkatesha ^a   Rowan, Brian G ^a  

^a MEDICAL COLLEGE OF OHIO   (United States)

Author keywords

Endometrial cancer cells; Estrogen receptor; Selective estrogen receptor modulator; Two dimensional gel electrophoresis

Indexed keywords

4 HYDROXYTAMOXIFEN; ACOLBIFENE; ESTRADIOL; ESTROGEN RECEPTOR; HEAT SHOCK PROTEIN 90; KERATIN; NUCLEAR RIBONUCLEOPROTEIN F; NUCLEOSIDE DIPHOSPHATE KINASE; NUCLEOSIDE DIPHOSPHATE KINASE B; PROTEIN SUBUNIT; RNA POLYMERASE II; SELECTIVE ESTROGEN RECEPTOR MODULATOR; TAMOXIFEN; UBIQUITIN CONJUGATING ENZYME; UNCLASSIFIED DRUG;

ADENOCARCINOMA; ARTICLE; CANCER CELL CULTURE; CONTROLLED STUDY; ENDOMETRIUM CANCER; FEMALE; GROWTH STIMULATION; HUMAN; HUMAN CELL; INCUBATION TIME; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN EXPRESSION; PROTEIN SECRETION; REGULATORY MECHANISM; TUMOR GROWTH; TWO DIMENSIONAL GEL ELECTROPHORESIS;

BIOLOGICAL MARKERS; CARRIER PROTEINS; CELL LINE, TUMOR; CELL PROLIFERATION; ENDOMETRIAL NEOPLASMS; ESTRADIOL; FEMALE; HETEROGENEOUS-NUCLEAR RIBONUCLEOPROTEIN GROUP F-H; HSP90 HEAT-SHOCK PROTEINS; HUMANS; KERATINS; LACTOFERRIN; NEOPLASM PROTEINS; PHOSPHOPROTEINS; PIPERIDINES; RECEPTORS, ESTROGEN; SELECTIVE ESTROGEN RECEPTOR MODULATORS; TAMOXIFEN; UBIQUITIN-CONJUGATING ENZYMES;

EID: 2442505539     PISSN: 03037207     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.mce.2004.01.003     Document Type: Article

References (81)

1. Arao Y., Kikuchi A., Ikeda K., Nomoto S., Horiguchi H., Kayama F. A + U-rich-element RNA-binding factor 1/heterogeneous nuclear ribonucleoprotein D gene expression is regulated by oestrogen in the rat uterus. Biochem. J. 361:2002;125-132
2. Auboeuf D., Honig A., Berget S.M., O'Malley B.W. Coordinate regulation of transcription and splicing by steroid receptor coregulators. Science. 298:2002;416-419
3. Baba H., Urano T., Okada K., Furukawa K., Nakayama E., Tanaka H., Iwasaki K., Shiku H. Two isotypes of murine nm23/nucleoside diphosphate kinase, nm23-M1 and nm23-M2, are involved in metastatic suppression of a murine melanoma line. Cancer Res. 55:1995;1977-1981
4. Berry M., Metzger D., Chambon P. Role of the two activating domains of the oestrogen receptor in the cell-type and promoter-context dependent agonistic activity of the anti-oestrogen 4-hydroxytamoxifen. EMBO J. 9:1990;2811-2818
5. Caligo M.A., Cipollini G., Fiore L., Calvo S., Basolo F., Collecchi P., Ciardiello F., Pepe S., Petrini M., Bevilacqua G. NM23 gene expression correlates with cell growth rate and S-phase. Int. J. Cancer. 60:1995;837-842
6. Caligo M.A., Cipollini G., Petrini M., Valentini P., Bevilacqua G. Down regulation of NM23.H1, NM23.H2 and c-myc genes during differentiation induced by 1, 25-dihydroxyvitamin D3. Leuk. Res. 20:1996;161-167
7. Carson J.H., Kwon S., Barbarese E. RNA trafficking in myelinating cells. Curr. Opin. Neurobiol. 8:1998;607-612
8. Chen J., Godt D., Gunsalus K., Kiss I., Goldberg M., Laski F.A. Cofilin/ADF is required for cell motility during Drosophila ovary development and oogenesis. Nat. Cell Biol. 3:2001;204-209
9. Choi I., Gudas L.J., Katzenellenbogen B.S. Regulation of keratin 19 gene expression by estrogen in human breast cancer cells and identification of the estrogen responsive gene region. Mol. Cell Endocrinol. 164:2000;225-237
10. Chopra P., Singh A., Koul A., Ramachandran S., Drlica K., Tyagi A.K., Singh Y. Cytotoxic activity of nucleoside diphosphate kinase secreted from Mycobacterium tuberculosis. Eur. J. Biochem. 270:2003;625-634
11. Couillard S., Gutman M., Labrie C., Belanger A., Candas B., Labrie F. Comparison of the effects of the antiestrogens EM-800 and tamoxifen on the growth of human breast ZR-75-1 cancer xenografts in nude mice. Cancer Res. 58:1998;60-64
12. Coutts A.S., Davie J.R., Dotzlaw H., Murphy L.C. Estrogen regulation of nuclear matrix-intermediate filament proteins in human breast cancer cells. J. Cell Biochem. 63:1996;174-184
13. Cowley S.M., Hoare S., Mosselman S., Parker M.G. Estrogen receptors alpha and beta form heterodimers on DNA. J. Biol. Chem. 272:1997;19858-19862
14. Donaldson S.H., Picher M., Boucher R.C. Secreted and cell-associated adenylate kinase and nucleoside diphosphokinase contribute to extracellular nucleotide metabolism on human airway surfaces. Am. J. Respir. Cell Mol. Biol. 26:2002;209-215
15. Dorjsuren D., Lin Y., Wei W., Yamashita T., Nomura T., Hayashi N., Murakami S. RMP, a novel RNA polymerase II subunit 5-interacting protein, counteracts transactivation by hepatitis B virus X protein. Mol. Cell Biol. 18:1998;7546-7555
16. Dutertre M., Smith C.L. Molecular mechanisms of selective estrogen receptor modulator (SERM) action. J. Pharmacol. Exp. Ther. 295:2000;431-437
17. Endoh H., Maruyama K., Masuhiro Y., Kobayashi Y., Goto M., Tai H., Yanagisawa J., Metzger D., Hashimoto S., Kato S. Purification and identification of p68 RNA helicase acting as a transcriptional coactivator specific for the activation function 1 of human estrogen receptor alpha. Mol. Cell Biol. 19:1999;5363-5372
18. Evans R.M. The steroid and thyroid hormone receptor superfamily. Science. 240:1988;889-895
19. Feng W., Webb P., Nguyen P., Liu X., Li J., Karin M., Kushner P.J. Potentiation of estrogen receptor activation function 1 (AF-1) by Src/JNK through a serine 118-independent pathway. Mol. Endocrinol. 15:2001;32-45
20. Fisher B., Costantino J.P., Redmond C.K., Fisher E.R., Wickerham D.L., Cronin W.M. Endometrial cancer in tamoxifen-treated breast cancer patients: findings from the National Surgical Adjuvant Breast and Bowel Project (NSABP) B-14. J. Natl. Cancer Inst. 86:1994;527-537
21. Fornander T., Rutqvist L.E., Cedermark B., Glas U., Mattsson A., Silfversward C., Skoog L., Somell A., Theve T., Wilking N. Adjuvant tamoxifen in early breast cancer: occurrence of new primary cancers. Lancet. 1:1989;117-120
22. Grabowski P.J. Splicing regulation in neurons: tinkering with cell-specific control. Cell. 20(92):1998;709-712
23. Harper M.J., Walpole A.L. A new derivative of triphenylethylene: effect on implantation and mode of action in rats. J. Reprod. Fertil. 13:1967;101-119
24. Jordan V.C. Tamoxifen: a personal retrospective. Lancet Oncol. 1:2000;43-49
25. Jordan V.C., Koerner S. Tamoxifen (ICI 46, 474) and the human carcinoma 8S oestrogen receptor. Eur. J. Cancer. 11:1975;205-206
26. Kato S., Endoh H., Masuhiro Y., Kitamoto T., Uchiyama S., Sasaki H., Masushige S., Gotoh Y., Nishida E., Kawashima H. Activation of the estrogen receptor through phosphorylation by mitogen-activated protein kinase. Science. 270:1995;1491-1494
27. Kirfel J., Magin T.M., Reichelt J. Keratins: a structural scaffold with emerging functions. Cell Mol. Life Sci. 60:2003;56-71
28. Klinge C.M. Estrogen receptor interaction with co-activators and co-repressors. Steroids. 65:2000;227-251
29. Klinge C.M. Estrogen receptor interaction with estrogen response elements. Nucleic Acids Res. 29:2001;2905-2919
30. Kuiper G.G., Enmark E., Pelto-Huikko M., Nilsson S., Gustafsson J.A. Cloning of a novel receptor expressed in rat prostate and ovary. Proc. Natl. Acad. Sci. U.S.A. 93:1996;5925-5930
31. Kumar V., Green S., Stack G., Berry M., Jin J.R., Chambon P. Functional domains of the human estrogen receptor. Cell. 51:1987;941-951
32. Labrie F., Labrie C., Belanger A., Simard J., Gauthier S., Luu-The V., Merand Y., Giguere V., Candas B., Luo S., Martel C., Singh S.M., Fournier M., Coquet A., Richard V., Charbonneau R., Charpenet G., Tremblay A., Tremblay G., Cusan L., Veilleux R. EM-652 (SCH 57068), a third generation SERM acting as pure antiestrogen in the mammary gland and endometrium. J. Steroid Biochem. Mol. Biol. 69:1999;51-84
33. Labrie F., Labrie C., Belanger A., Simard J., Giguere V., Tremblay A., Tremblay G. EM-652 (SCH57068), a pure SERM having complete antiestrogenic activity in the mammary gland and endometrium. J. Steroid Biochem. Mol. Biol. 79:2001;213-225
34. Lanz R.B., McKenna N.J., Onate S.A., Albrecht U., Wong J., Tsai S.Y., Tsai M.J., O'Malley B.W. A steroid receptor coactivator, SRA, functions as an RNA and is present in an SRC-1 complex. Cell. 97:1999;17-27
35. Lee H., Jiang F., Wang Q., Nicosia S.V., Yang J., Su B., Bai W. MEKK1 activation of human estrogen receptor alpha and stimulation of the agonistic activity of 4-hydroxytamoxifen in endometrial and ovarian cancer cells. Mol. Endocrinol. 14:2000;1882-1896
36. Leone A., Flatow U., King C.R., Sandeen M.A., Margulies I.M., Liotta L.A., Steeg P.S. Reduced tumor incidence, metastatic potential, and cytokine responsiveness of nm23-transfected melanoma cells. Cell. 65:1991;25-35
37. Leone A., Flatow U., VanHoutte K., Steeg P.S. Transfection of human nm23-H1 into the human MDA-MB-435 breast carcinoma cell line: effects on tumor metastatic potential, colonization and enzymatic activity. Oncogene. 8:1993;2325-2333
38. Lin K.H., Wang W.J., Wu Y.H., Cheng S.Y. Activation of antimetastatic Nm23-H1 gene expression by estrogen and its alpha-receptor. Endocrinology. 143:2002;467-475
39. Lonard D.M., Nawaz Z., Smith C.L., O'Malley B.W. The 26S proteasome is required for estrogen receptor-alpha and coactivator turnover and for efficient estrogen receptor-alpha transactivation. Mol. Cell. 5:2000;939-948
40. Luo S., Sourla A., Labrie C., Gauthier S., Merand Y., Belanger A., Labrie F. Effect of twenty-four-week treatment with the antiestrogen EM-800 on estrogen-sensitive parameters in intact and ovariectomized mice. Endocrinology. 139:1998;2645-2656
41. Maciver S.K., Weeds A.G. Actophorin preferentially binds monomeric ADP-actin over ATP-bound actin: consequences for cell locomotion. FEBS Lett. 347:1994;251-256
42. Mandlekar S., Kong A.N. Mechanisms of tamoxifen-induced apoptosis. Apoptosis. 6:2001;469-477
43. Martel C., Labrie C., Belanger A., Gauthier S., Merand Y., Li X., Provencher L., Candas B., Labrie F. Comparison of the effects of the new orally active antiestrogen EM-800 with ICI 182-780 and toremifene on estrogen-sensitive parameters in the ovariectomized mouse. Endocrinology. 139:1998;2486-2492
44. Martel C., Picard S., Richard V., Belanger A., Labrie C., Labrie F. Prevention of bone loss by EM-800 and raloxifene in the ovariectomized rat. J. Steroid Biochem. Mol. Biol. 74:2000;45-56
45. Matunis E.L., Matunis M.J., Dreyfuss G. Association of individual hnRNP proteins and snRNPs with nascent transcripts. J. Cell Biol. 121:1993;219-228
46. Matunis M.J., Xing J., Dreyfuss G. The hnRNP F protein: unique primary structure, nucleic acid-binding properties, and subcellular localization. Nucleic Acids Res. 22:1994;1059-1067
47. Mayeda A., Krainer A.R. Regulation of alternative pre-mRNA splicing by hnRNP A1 and splicing factor SF2. Cell. 68:1992;365-375
48. McKenna N.J., Lanz R.B., O'Malley B.W. Nuclear receptor coregulators: cellular and molecular biology. Endocr. Rev. 20:1999;321-344
49. McKenna N.J., O'Malley B.W. From ligand to response: generating diversity in nuclear receptor coregulator function. J. Steroid Biochem. Mol. Biol. 74:2000;351-356
50. Mosselman S., Polman J., Dijkema R. ER beta: identification and characterization of a novel human estrogen receptor. FEBS Lett. 19(392):1996;49-53
51. Mueller S.O., Korach K.S. Estrogen receptors and endocrine diseases: lessons from estrogen receptor knockout mice. Curr. Opin. Pharmacol. 1:2001;613-619
52. Nagaoka R., Abe H., Kusano K., Obinata T. Concentration of cofilin, a small actin-binding protein, at the cleavage furrow during cytokinesis. Cell Motil. Cytoskeleton. 30:1995;1-7
53. Nakamori S., Ishikawa O., Ohigashi H., Imaoka S., Sasaki Y., Kameyama M., Kabuto T., Furukawa H., Iwanakga T., Kimura N. Clinicopathological features and prognostic significance of nucleoside diphosphate kinase/nm23 gene product in human pancreatic exocrine neoplasms. Int. J. Pancreatol. 14:1993;125-133
54. Nakielny S., Dreyfuss G. Nuclear export of proteins and RNAs. Curr. Opin. Cell Biol. 9:1997;420-429
55. Nawaz Z., Lonard D.M., Dennis A.P., Smith C.L., O'Malley B.W. Proteasome-dependent degradation of the human estrogen receptor. Proc. Natl. Acad. Sci. U.S.A. 96:1999;1858-1862
56. Nuber U., Schwarz S., Kaiser P., Schneider R., Scheffner M. Cloning of human ubiquitin-conjugating enzymes UbcH6 and UbcH7 (E2-F1) and characterization of their interaction with E6-AP and RSP5. J. Biol. Chem. 271:1996;2795-2800
57. Ogawa S., Inoue S., Watanabe T., Hiroi H., Orimo A., Hosoi T., Ouchi Y., Muramatsu M. The complete primary structure of human estrogen receptor beta (hER beta) and its heterodimerization with ER alpha in vivo and in vitro. Biochem. Biophys. Res. Commun. 243:1998;122-126
58. Ostareck D.H., Ostareck-Lederer A., Wilm M., Thiele B.J., Mann M., Hentze M.W. mRNA silencing in erythroid differentiation: hnRNP K and hnRNP E1 regulate 15-lipoxygenase translation from the 3′ end. Cell. 89:1997;597-606
59. Paramio J.M., Jorcano J.L. Beyond structure: do intermediate filaments modulate cell signalling. Bioessays. 24:2002;836-844
60. Pettersson K., Grandien K., Kuiper G.G., Gustafsson J.A. Mouse estrogen receptor beta forms estrogen response element-binding heterodimers with estrogen receptor alpha. Mol. Endocrinol. 11:1997;1486-1496
61. Powers C.A., Mathur M., Raaka B.M., Ron D., Samuels H.H. TLS (translocated-in-liposarcoma) is a high-affinity interactor for steroid, thyroid hormone, and retinoid receptors. Mol. Endocrinol. 12:1998;4-18
62. Pratt W.B., Toft D.O. Steroid receptor interactions with heat shock protein and immunophilin chaperones. Endocr. Rev. 18:1997;306-360
63. Ramachandran C., Catelli M.G., Schneider W., Shyamala G. Estrogenic regulation of uterine 90-kilodalton heat shock protein. Endocrinology. 123:1988;956-961
64. Shyamala G., Gauthier Y., Moore S.K., Catelli M.G., Ullrich S.J. Estrogenic regulation of murine uterine 90-kilodalton heat shock protein gene expression. Mol. Cell Biol. 9:1989;3567-3570
65. Simard J., Labrie C., Belanger A., Gauthier S., Singh S.M., Merand Y., Labrie F. Characterization of the effects of the novel non-steroidal antiestrogen EM-800 on basal and estrogen-induced proliferation of T-47D, ZR-75-1 and MCF-7 human breast cancer cells in vitro. Int. J. Cancer. 73:1997;104-112
66. Smith C.L., DeVera D.G., Lamb D.J., Nawaz Z., Jiang Y.H., Beaudet A.L., O'Malley B.W. Genetic ablation of the steroid receptor coactivator-ubiquitin ligase, E6-AP, results in tissue-selective steroid hormone resistance and defects in reproduction. Mol. Cell Biol. 22:2002;525-535
67. Smith C.L., Nawaz Z., O'Malley B.W. Coactivator and corepressor regulation of the agonist/antagonist activity of the mixed antiestrogen, 4-hydroxytamoxifen. Mol. Endocrinol. 11:1997;657-666
68. Sourla A., Luo S., Labrie C., Belanger A., Labrie F. Morphological changes induced by 6-month treatment of intact and ovariectomized mice with tamoxifen and the pure antiestrogen EM-800. Endocrinology. 138:1997;5605-5617
69. Steeg P.S., Bevilacqua G., Kopper L., Thorgeirsson U.P., Talmadge J.E., Liotta L.A., Sobel M.E. Evidence for a novel gene associated with low tumor metastatic potential. J. Natl. Cancer Inst. 80:1988;200-204
70. Tang P.Z., Gannon M.J., Andrew A., Miller D. Evidence for oestrogenic regulation of heat shock protein expression in human endometrium and steroid-responsive cell lines. Eur. J. Endocrinol. 133:1995;598-605
71. Terenius L. Structure-activity relationships of anti-oestrogens with regard to interaction with 17-beta-oestradiol in the mouse uterus and vagina. Acta Endocrinol. (Copenh.). 66:1971;431-447
72. Tora L., White J., Brou C., Tasset D., Webster N., Scheer E., Chambon P. The human estrogen receptor has two independent nonacidic transcriptional activation functions. Cell. 59:1989;477-487
73. Tremblay G.B., Tremblay A., Copeland N.G., Gilbert D.J., Jenkins N.A., Labrie F., Giguere V. Cloning, chromosomal localization, and functional analysis of the murine estrogen receptor beta. Mol. Endocrinol. 11:1997;353-365
74. Tsai M.J., O'Malley B.W. Molecular mechanisms of action of steroid/thyroid receptor superfamily members. Annu. Rev. Biochem. 63:1994;451-486
75. Walinder O. Identification of a phosphate-incorporating protein from bovine liver as nucleoside diphosphate kinase and isolation of 1-32P-phosphohistidine, 3-32P-phosphohistidine, and N-epsilon-32P-phospholysine from erythrocytic nucleoside diphosphate kinase, incubated with adenosine triphosphate-32P. J. Biol. Chem. 243:1968;3947-3952
76. Walter S., Buchner J. Molecular chaperones - cellular machines for protein folding. Angew. Chem. Int. Ed. Engl. 41:2002;1098-1113
77. Webb P., Nguyen P., Shinsako J., Anderson C., Feng W., Nguyen M.P., Chen D., Huang S.M., Subramanian S., McKinerney E., Katzenellenbogen B.S., Stallcup M.R., Kushner P.J. Estrogen receptor activation function 1 works by binding p160 coactivator proteins. Mol. Endocrinol. 12:1998;1605-1618
78. Weissman A.M. Themes and variations on ubiquitylation. Nat. Rev. Mol. Cell Biol. 2:2001;169-178
79. Willems R., Slegers H., Rodrigus I., Moulijn A.C., Lenjou M., Nijs G., Berneman Z.N., Van Bockstaele D.R. Extracellular nucleoside diphosphate kinase NM23/NDPK modulates normal hematopoietic differentiation. Exp. Hematol. 30:2002;640-648
80. Wu W.X., Derks J.B., Zhang Q., Nathanielsz P.W. Changes in heat shock protein-90 and -70 messenger ribonucleic acid in uterine tissues of the ewe in relation to parturition and regulation by estradiol and progesterone. Endocrinology. 137:1996;5685-5693
81. Yan F., Gao X., Lonard D.M., Nawaz Z. Specific ubiquitin-conjugating enzymes promote degradation of specific nuclear receptor coactivators. Mol. Endocrinol. 17:2003;1315-1331