Pharmacologic therapies for complex regional pain syndrome

Current Pain and Headache Reports

Volumn 11, Issue 1, 2007, Pages 38-43

  Mackey, Sean ^a   Feinberg, Steven ^b  

^a STANFORD UNIVERSITY   (United States)

^b NONE

Author keywords

[No Author keywords available]

Indexed keywords

ADRENERGIC RECEPTOR STIMULATING AGENT; ALENDRONIC ACID; AMANTADINE; ANTICONVULSIVE AGENT; ANTIDEPRESSANT AGENT; ANTIINFLAMMATORY AGENT; BISPHOSPHONIC ACID DERIVATIVE; CARBAMAZEPINE; CLONIDINE; DULOXETINE; GABAPENTIN; IMIPRAMINE; LIDOCAINE; MEMANTINE; MIRTAZAPINE; MORPHINE; N METHYL DEXTRO ASPARTIC ACID RECEPTOR BLOCKING AGENT; NARCOTIC ANALGESIC AGENT; OXCARBAZEPINE; PLACEBO; PREDNISOLONE; PREGABALIN; RESERPINE; SEROTONIN UPTAKE INHIBITOR; SODIUM CHANNEL BLOCKING AGENT; STEROID; THALIDOMIDE; TRICYCLIC ANTIDEPRESSANT AGENT; UNINDEXED DRUG; VENLAFAXINE;

ADDICTION; CLINICAL PROTOCOL; CLINICAL TRIAL; COGNITIVE DEFECT; COMPLEX REGIONAL PAIN SYNDROME; CONSTIPATION; DRUG EFFICACY; DRUG MECHANISM; DRUG OVERDOSE; DRUG TOLERABILITY; HUMAN; HYPERALGESIA; LIBIDO; MENSTRUAL IRREGULARITY; NAUSEA; NEUROPATHIC PAIN; PRESCRIPTION; QUALITY OF LIFE; RANDOMIZATION; RESPIRATION DEPRESSION; REVIEW; SIDE EFFECT; SOMNOLENCE; TESTOSTERONE BLOOD LEVEL; UNSPECIFIED SIDE EFFECT; VOMITING;

ADRENERGIC AGENTS; ANALGESICS, OPIOID; ANTI-INFLAMMATORY AGENTS, NON-STEROIDAL; ANTICONVULSANTS; ANTIDEPRESSIVE AGENTS; COMPLEX REGIONAL PAIN SYNDROMES; DIPHOSPHONATES; HUMANS; RECEPTORS, N-METHYL-D-ASPARTATE; SODIUM CHANNEL BLOCKERS; THALIDOMIDE;

EID: 33846528525     PISSN: 15313433     EISSN: None     Source Type: Journal    
DOI: 10.1007/s11916-007-0020-z     Document Type: Review

References (60)

1. Reflex Sympathetic Dystrophy Syndrome Association of America. http://www.rsds.org/. Accessed November 8, 2006.
2. Stanton-Hicks M: An updated interdisciplinary clinical pathway for CRPS: report of an expert panel. Pain Practice 2002, 2:1-16.
3. Mellick LB, Mellick GA: Successful treatment of reflex sympathetic dystrophy with gabapentin. Am J Emerg Med 1995, 13:96.
4. Fink K, Dooley DJ, Meder WP, et al.: Inhibition of neuronal Ca(2+) influx by gabapentin and pregabalin in the human neocortex. Neuropharmacology 2002, 42:229-236.
5. Backonja M, Glanzman RL: Gabapentin dosing for neuropathic pain: evidence from randomized, placebo-controlled clinical trials. Clin Ther 2003, 25:81-104.
6. Rowbotham M, Harden N, Stacey B, et al.: Gabapentin for the treatment of postherpetic neuralgia: a randomized controlled trial. JAMA 1998, 280:1837-1842.
7. van de Vusse AC, Stomp-van den Berg SG, Kessels AH, Weber WE: Randomised controlled trial of gabapentin in complex regional pain syndrome type 1 [ISRCTN84121379]. BMC Neurol 2004, 4:13.
8. Serpell MG: Gabapentin in neuropathic pain syndromes: a randomised, double-blind, placebo-controlled trial. Pain 2002, 99:557-566.
9. Gilron I, Bailey JM, Tu D, et al.: Morphine, gabapentin, or their combination for neuropathic pain. N Engl J Med 2005, 352:1324-1334.
10. Dworkin RH, Corbin AE, Young JP Jr, et al.: Pregabalin for the treatment of postherpetic neuralgia: a randomized, placebo-controlled trial. Neurology 2003, 60:1274-1283.
11. Rosenstock J, Tuchman M, LaMoreaux L, Sharma U: Pregabalin for the treatment of painful diabetic peripheral neuropathy: a double-blind, placebo-controlled trial. Pain 2004, 110:628-638.
12. Harke H, Gretenkort P, Ladleif HU, et al.: The response of neuropathic pain and pain in complex regional pain syndrome I to carbamazepine and sustained-release morphine in patients pretreated with spinal cord stimulation: a double-blinded randomized study. Anesth Analg 2001, 92:488-495.
13. Beydoun A, Shaibani A, Hopwood M, Wan Y: Oxcarbazepine in painful diabetic neuropathy: results of a dose-ranging study. Acta Neurol Scand 2006, 113:395-404.
14. Beydoun A, Kobetz SA, Carrazana EJ: Efficacy of oxcarbazepine in the treatment of painful diabetic neuropathy. Clin J Pain 2004, 20:174-178.
15. Sindrup SH, Jensen TS: Efficacy of pharmacological treatments of neuropathic pain: an update and effect related to mechanism of drug action. Pain 1999, 83:389-400.
16. Raja SN, Haythornthwaite JA, Pappagallo M, et al.: Opioids versus antidepressants in postherpetic neuralgia: a randomized, placebo-controlled trial. Neurology 2002, 59:1015-1021.
17. Sudoh Y, Cahoon EE, Gerner P, Wang GK: Tricyclic antidepressants as long-acting local anesthetics. Pain 2003, 103:49-55.
18. Max MB, Lynch SA, Muir J, et al.: Effects of desipramine, amitriptyline, and fluoxetine on pain in diabetic neuropathy. N Engl J Med 1992, 326:1250-1256.
19. Sindrup SH, Bach FW, Madsen C, et al.: Venlafaxine versus imipramine in painful polyneuropathy: a randomized, controlled trial. Neurology 2003, 60:1284-1289.
20. Raskin J, Pritchett YL, Wang F, et al.: A double-blind, randomized multicenter trial comparing duloxetine with placebo in the management of diabetic peripheral neuropathic pain. Pain Med 2005, 6:346-356.
21. Raskin J, Wang F, Pritchett YL, Goldstein DJ: Duloxetine for patients with diabetic peripheral neuropathic pain: a 6-month open-label safety study. Pain Med 2006, 7:373-385.
22. Perahia DG, Pritchett YL, Desaiah D, Raskin J: Efficacy of duloxetine in painful symptoms: an analgesic or antidepressant effect? Int Clin Psychopharmacol 2006, 21:311-317.
23. Dellemijn P: Are opioids effective in relieving neuropathic pain? Pain 1999, 80:453-462.
24. Watson CP, Babul N: Efficacy of oxycodone in neuropathic pain: a randomized trial in postherpetic neuralgia. Neurology 1998, 50:1837-1841.
25. Watson CP, Moulin D, Watt-Watson J, et al.: Controlled-release oxycodone relieves neuropathic pain: a randomized controlled trial in painful diabetic neuropathy. Pain 2003, 105:71-78.
26. Chu LF, Clark DJ, Angst MS: Opioid tolerance and hyperalgesia in chronic pain patients after one month of oral morphine therapy: a preliminary prospective study. J Pain 2006, 7:43-48.
27. Daniell HW: Hypogonadism in men consuming sustained-action oral opioids. J Pain 2002, 3:377-384.
28. Zhao Z, Chen SR, Eisenach JC, et al.: Spinal cyclooxygenase-2 is involved in development of allodynia after nerve injury in rats. Neuroscience 2000, 97:743-748.
29. Ossipov MH, Jerussi TP, Ren K, et al.: Differential effects of spinal (R)-ketoprofen and (S)-ketoprofen against signs of neuropathic pain and tonic nociception: evidence for a novel mechanism of action of (R)-ketoprofen against tactile allodynia. Pain 2000, 87:193-199.
30. Bianchi C, Rossi S, Turi S, et al.: Long-term functional outcome measures in corticosteroid-treated complex regional pain syndrome. Eura Medicophys 2006, 42:103-111.
31. Christensen K, Jensen EM, Noer I: The reflex dystrophy syndrome response to treatment with systemic corticosteroids. Acta Chir Scand 1982, 148:653-655.
32. Kalita J, Vajpayee A, Misra UK: Comparison of prednisolone with piroxicam in complex regional pain syndrome following stroke: a randomized controlled trial. QJM 2006, 99:89-95.
33. Kingery WS: A critical review of controlled clinical trials for peripheral neuropathic pain and complex regional pain syndromes. Pain 1997, 73:123-139.
34. Oyen WJ, Arntz IE, Claessens RM, et al.: Reflex sympathetic dystrophy of the hand: an excessive inflammatory response? Pain 1993, 55:151-157.
35. Zuurmond WW, Langendijk PN, Bezemer PD, et al.: Treatment of acute reflex sympathetic dystrophy with DMSO 50% in a fatty cream. Acta Anaesthesiol Scand 1996, 40:364-367.
36. Zollinger PE, Tuinebreijer WE, Kreis RW, Breederveld RS: Effect of vitamin C on frequency of reflex sympathetic dystrophy in wrist fractures: a randomised trial. Lancet 1999, 354:2025-2028.
37. Pappagallo M, Breuer B, Schneider A, Sperber K: Treatment of chronic mechanical spinal pain with intravenous pamidronate: a review of medical records. J Pain Symptom Manage 2003, 26:678-683.
38. Kubalek I: Treatment of reflex sympathetic dystrophy with pamidronate: 29 cases. Rheumatology (Oxford) 2001, 40:1394-1397.
39. Manicourt DH, Brasseur JP, Boutsen Y, et al.: Role of alendronate in therapy for posttraumatic complex regional pain syndrome type I of the lower extremity. Arthritis Rheum 2004, 50:3690-3697.
40. Adami S, Fossaluzza V, Gatti D, et al.: Bisphosphonate therapy of reflex sympathetic dystrophy syndrome. Ann Rheum Dis 1997, 56:201-204.
41. Robinson JN, Sandom J, Chapman PT: Efficacy of pamidronate in complex regional pain syndrome type I. Pain Med 2004, 5:276-280.
42. Varenna M, Zucchi F, Ghiringhelli D, et al.: Intravenous clodronate in the treatment of reflex sympathetic dystrophy syndrome. A randomized, double blind, placebo controlled study. J Rheumatol 2000, 27:1477-1483.
43. Galer BS, Miller KV, Rowbotham MC: Response to intravenous lidocaine infusion differs based on clinical diagnosis and site of nervous system injury. Neurology 1993, 43:1233-1235.
44. Wallace MS, Ridgeway BM, Leung AY, et al.: Concentration-effect relationship of intravenous lidocaine on the allodynia of complex regional pain syndrome types I and II. Anesthesiology 2000, 92:75-83.
45. Correll GE, Maleki J, Gracely EJ, et al.: Subanesthetic ketamine infusion therapy: a retrospective analysis of a novel therapeutic approach to complex regional pain syndrome. Pain Med 2004, 5:263-275.
46. Nelson KA, Park KM, Robinovitz E, et al.: High-dose oral dextromethorphan versus placebo in painful diabetic neuropathy and postherpetic neuralgia. Neurology 1997, 48:1212-1218.
47. Galer BS, Lee D, Ma T, et al.: MorphiDex (morphine sulfate/ dextromethorphan hydrobromide combination) in the treatment of chronic pain: three multicenter, randomized, double-blind, controlled clinical trials fail to demonstrate enhanced opioid analgesia or reduction in tolerance. Pain 2005, 115:284-295.
48. Kleinbohl D, Gortelmeyer R, Bender HJ, Holzl R: Amantadine sulfate reduces experimental sensitization and pain in chronic back pain patients. Anesth Analg 2006, 102:840-847.
49. Maier C, Dertwinkel R, Mansourian N, et al.: Efficacy of the NMDA-receptor antagonist memantine in patients with chronic phantom limb pain - results of a randomized double-blinded, placebo-controlled trial. Pain 2003, 103:277-283.
50. Te AE: A modern rationale for the use of phenoxybenzamine in urinary tract disorders and other conditions. Clin Ther 2002, 24:851-861; discussion 837.
51. Muizelaar JP, Kleyer M, Hertogs IA, DeLange DC: Complex regional pain syndrome (reflex sympathetic dystrophy and causalgia): management with the calcium channel blocker nifedipine and/or the alpha-sympathetic blocker phenoxybenzamine in 59 patients. Clin Neurol Neurosurg 1997, 99:26-30.
52. Raja SN, Turnquist JL, Meleka S, Campbell JN: Monitoring adequacy of alpha-adrenoceptor blockade following systemic phentolamine administration. Pain 1996, 64:197-204.
53. Davies PS, Galer BS: Review of lidocaine patch 5% studies in the treatment of postherpetic neuralgia. Drugs 2004, 64:937-947.
54. Devers A, Galer BS: Topical lidocaine patch relieves a variety of neuropathic pain conditions: an open-label study. Clin J Pain 2000, 16:205-208.
55. Rowbotham MC, Davies PS, Verkempinck C, Galer BS: Lidocaine patch: double-blind controlled study of a new treatment method for post-herpetic neuralgia. Pain 1996, 65:39-44.
56. Sawynok J: Topical analgesics in neuropathic pain. Curr Pharm Des 2005, 11:2995-3004.
57. Peikert A, Hentrich M, Ochs G: Topical 0.025% capsaicin in chronic post-herpetic neuralgia: efficacy, predictors of response and long-term course. J Neurol 1991, 238:452-456.
58. Robbins WR, Staats PS, Levine J, et al.: Treatment of intractable pain with topical large-dose capsaicin: preliminary report. Anesth Analg 1998, 86:579-583.
59. Ching DW, McClintock A, Beswick F: Successful treatment with low-dose thalidomide in a patient with both Behcet's disease and complex regional pain syndrome type I: case report. J Clin Rheumatol 2003, 9:96-98.
60. Schwartzman RJ, Chevlen E, Bengtson K: Thalidomide has activity in treating complex regional pain syndrome. Arch Intern Med 2003, 163:1487-1488; author reply 1488.