Are opioids effective in relieving neuropathic pain?

Pain

Volumn 80, Issue 3, 1999, Pages 453-462

  Dellemijn, Paul ^a  

^a ST JOSEPH HOSPITAL   (Netherlands)

Author keywords

Experimental animal models; Human neuropathic pain; Neuropathic pain; Opioid

Indexed keywords

BUPRENORPHINE; CLONIDINE; CODEINE; DIAZEPAM; FENTANYL; IBUPROFEN; KETAMINE; LIDOCAINE; MORPHINE; NAPROXEN; OPIATE; OPIATE RECEPTOR; OXYCODONE;

ANALGESIA; ANIMAL MODEL; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; DOSE RESPONSE; DOUBLE BLIND PROCEDURE; DRUG EFFICACY; FOLLOW UP; HUMAN; INTRAMUSCULAR DRUG ADMINISTRATION; INTRAVENOUS DRUG ADMINISTRATION; METHODOLOGY; NEUROPATHY; NOMENCLATURE; NONHUMAN; OPIATE ADDICTION; ORAL DRUG ADMINISTRATION; PAIN; PAIN ASSESSMENT; PRIORITY JOURNAL; QUALITY OF LIFE; RANDOMIZED CONTROLLED TRIAL; REVIEW;

ANALGESICS, OPIOID; ANIMALS; HUMANS; NERVOUS SYSTEM DISEASES; NEURALGIA;

EID: 0032910977     PISSN: 03043959     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0304-3959(98)00256-5     Document Type: Review

References (90)

1. Arnér S., Arnér B. Differential effects of epidural morphine in treatment of cancer related pain. Acta Anaesth. Scand. 29:1985;32-36.
2. Arnér, S. and Meyerson, B.A., Lack of analgesic effect of opioids on neuropathic and idiopathic forms of pain, Pain, 33 (1988a) 11-23.
3. Arnér, S. and Meyerson, B.A., Reply to Howard Fields on 'can opiates relieve neuropathic pain?', Pain, 35 (1988b) 366-367.
4. Arnér S., Meyerson B.A. Opioids in neuropathic pain. Pain Dig. 3:1993;15-22.
5. Asbury A.K., Fields H.L. Pain due to peripheral nerve damage: a hypothesis. Neurology. 34:1984;1587-1590.
6. Attal N., Chen Y.L., Kayser V., Guilbaud G.L. Behavioural evidence that systemic morphine may modulate a phasic pain-related behaviour in a rat model of peripheral mononeuropathy. Pain. 47:1991;65-70.
7. Babul N., Darke A.C., Hagen N. Hydropmorphone metabolite accumulation in renal failure. J. Pain Symptom Manage. 10:1995;184-186.
8. Bennett, G.J., Neuropathic pain. In: R. Melzack and P.D. Wall (Eds.), Textbook of Pain, Churchill Livingstone, Edinburgh, 1994a, pp. 201-224.
9. Bennett, G.J., Animal models of neuropathic pain. In: G.F. Gebhart, D.L. Hammond and T.S. Jensen (Eds.), Proceedings of the 7th World Congress on Pain, IASP Press, Seatle, WA, 1994b, pp. 495-510.
10. Bennett G.J., Xie Y.-K. A peripheral mononeuropathy in rat that produces disorders of pain sensation like those in man. Pain. 33:1988;87-107.
11. Besse D., Lombard M.C., Zakac J.M., Roques B.P., Besson J.-M. Pre- and postsynaptic distribution of mu, delta and kappa opioid receptors in the superficial layers of the cervical dorsal horn of the rat spinal cord. Brain Res. 521:1990;15-22.
12. Besson J.-M., Chaouch A. Peripheral and spinal mechanisms of nociception. Physiol. Rev. 67:1987;67-186.
13. Bouckoms A.J., Masand P., Murray G.B., Cassem E.H., Stern T.A., Tesar G.E. Chronic non-malignant pain treated with long-term oral narcotic analgesics. Ann. Clin. Psychiatry. 4:1992;185-192.
14. Chapman C.R., Feather B.W. Effect of diazepam on human pain tolerance and pain sensitivity. Psychosom. Med. 35:1973;330-340.
15. Cherny N.I., Thaler H.T., Friedlander-Klar H., Lapin J., Foley K.M. Opioid responsiveness of cancer pain syndromes caused by neuropathic or nociceptive mechanisms: a combined analysis of controlled single-dose studies. Neurology. 44:1994;857-861.
16. Cleeland C.S., Rotondi A., Brechner T., Levin A., MacDonald N., Portenoy R.K., Schutta H., McEniry M. A model for the treatment of cancer pain. J. Pain Symptom Manage. 1:1986;209-215.
17. Colpaert F.C., Meert T., De Witte P., Schmitt P. Further evidence validating adjuvant arthritis as an experimental model of chronic pain in the rat. Life Sci. 31:1982;67-75.
18. DeLeo J.A., Coombs D.W., Willenbring S., Colburn R.W., Fromm C., Wagner R., Twitchell B.B. Characterization of a neuropathic pain model: sciatic neurolysis in the rat. Pain. 56:1994;9-16.
19. Dellemijn P.L.I., Fields H.L. Do benzodiazepines have a role in chronic pain management. Pain. 57:1994;137-152.
20. Dellemijn, P.L.I., Fields, H.L., Allen, R.R., McKay, W.R. and Rowbotham, M.C., The interpretation of pain relief and sensory changes following sympathetic blockade, Brain, 117 (1994a) 1475-1487.
21. Dellemijn, P.L.I., Verbiest, H.B.C., van Vliet, J.J., Roos, P.J. and Vecht, Ch.J., Medical therapy of malignant nerve pain. A double-blind explanatory trial with naproxen and slow-release morphine, Eur. J. Cancer, 30 (1994b) 1244-1250.
22. Dellemijn P.L.I., Vecht Ch.J. Towards better pain treatment in cancer. Anti-Cancer Drugs. 7:1996;3-26.
23. Dellemijn P.L.I., Vanneste J.A.L. Randomised double-blind active-placebo-controlled cross-over trial of intravenous fentanyl in neuropathic pain. Lancet. 349:1997;753-758.
24. Dellemijn P.L.I., van Duijn H., Vanneste J.A.L. Prolonged transdermal fentanyl in neuropathic pain. J. Pain Symptom Manage. 16:1998;220-229.
25. Desmeules J.A., Kayser V., Guilbaud G. Selective opioid receptor agonists modulate mechanical allodynia in an animal model of neuropathic pain. Pain. 53:1993;277-285.
26. Devor M., White D.M., Goetzl E.J., Levine J.D. Eicosanoids, but not tachykinins, excite C-fiber endings in rat sciatic nerve-end neuromas. NeuroReport. 3:1992;21-24.
27. + channel immunolocalization in peripheral mammalian axons and changes following nerve injury and neuroma formation. J. Neurosci. 13:1993;1976-1992.
28. Dubner R. A call for more science, not more rhetoric, regarding opioids and neuropathic pain (editorial). Pain. 47:1991;1-2.
29. Eide P.K., Jorum E., Stubhaug A., Bremnes J., Breivik H. Relief of post-herpetic neuralgia with the N-methyl-D-aspartic acid receptor antagonist ketamine: a double-blind cross-over comparison with morphine, and placebo. Pain. 58:1994;347-354.
30. Fields H.L. Can opiates relieve neuropathic pain? Pain. 35:1988;365-367.
31. Fields H.L. Depression and pain: a neurobiological model. Neuropsychiatr. Neuropsychol. Behav. Neurol. 4:1991;83-92.
32. Fields, H.L. and Rowbotham, M.C., Multiple mechanisms of neuropathic pain: a clinical perspective. In: G.F. Gebhart, D.L Hammond and T.S. Jensen (Eds.), Proceedings of the 7th World Congress on Pain: Progress in Pain Research And Management, Vol. 2, IASP Press, Seatle, WA, 1994, pp. 437-454.
33. France R.D., Urban B.J., Keefe F.J. Long-term use of narcotic analgesics in chronic pain. Soc. Sci. Med. 19:1984;1379-1382.
34. Galer B.S., Coyle N., Pasternak G.W., Portenoy R.K. Individual variability in the response to different opioids: report of five cases. Pain. 49:1992;87-91.
35. Gracely R.H., McGrath P., Dubner R. Validity and sensitivity of ratio scales of sensory and affective verbal pain descriptors: manipulation of affect by diazepam. Pain. 5:1978;19-29.
36. Gracely R.H., Dubner R., McGrath P. Fentanyl reduces the intensity of painful toothpulp sensations: controlling for detection of active drugs. Anesth. Analg. 61:1982;751-755.
37. Hanks, G.W., Opioid-responsive and opioid non-responsive pain in cancer. In: J.C.D. Wells and C.J. Woolf (Eds.), Pain Mechanisms and Management. Br. Med. Bull., Churchill Livingstone, Edinburgh, 1991, pp. 718-731.
38. Hansson P. Pain: Clin. Updates. 2(3):1994;1-4.
39. Hylden J.L.K., Thomas D.A., Iadorola M.J., Nahin M.J., Dubner R. Spinal opioid analgesic effects are enhanced in a model of unilateral inflammation/hyperalgesia: possible role of noradrenergic mechanisms. Eur. J. Pharmacol. 194:1991;135-143.
40. Inturissi, C.E. and Colburn, W.A., Application of pharmacokinetic-pharmacodynamic modeling to analgesia. In: K.M. Foley and C.E. Inturissi (Eds.), Advances in Pain Research and Therapy, Vol. 8. Opioid Analgesics in the Management of Clinical Pain, Raven Press, New York, 1986, pp. 441-452.
41. Jadad J.R., Carroll D., Glynn C.J., Moore R.A., McQuay H.J. Morphine responsiveness of chronic pain: double blind randomised crossover study with patient controlled analgesia. Lancet. 339(ii):1992;1367-1371.
42. Kalso E., Vainio A. Morphine and oxycodone hydrochloride in the management of cancer pain. Clin. Pharmacol. Ther. 47:1990;639-646.
43. Kim S.H., Chung J.M. An experimental model for peripheral neuropathy produced by spinal nerve ligation in the rat. Pain. 50:1992;355-363.
44. Kupers R.C., Konings H., Adriaensen H., Gybels J.M. Morphine differentially affects the sensory and affective pain ratings in neurogenic and idiopathic forms of pain. Pain. 47:1991;5-12.
45. Kupers R., Gybels J. The consumption is increased in rats with nociceptive pain but not with neuropathic pain. Pain. 60:1995;137-141.
46. Manfredi P.L., Borsook D., Chandler S.W., Payne R. Intravenous methadone for cancer pain unrelieved by morphine and hydromorphone: clinical observations. Pain. 70:1997;99-101.
47. Markus H., Pomeranz B., Krushelnycky D. Spread of saphenous somatotopic projection map in spinal cord and hypersensitivity of the foot after chronic denervation in adult rat. Brain Res. 296:1984;27-39.
48. Maves, T.J., Pechman, P.S., Gebhart, G.F. and Meller, S.T., Continuous infusion of acidified saline around the rat sciatic nerve produces a reversible thermal hyperalgesia, In: Abstracts 7th World Congress on Pain, IASP Press, Seatle, WA, 1993, p. 31.
49. Max M.B., Schafer S.C., Culnane M., Dubner R., Gracely R.H. Association of pain relief with drug side-effects in postherpetic neuralgia: a single dose study of clonidine, codeine, ibuprofen and placebo. Clin. Pharmacol. Ther. 43:1988;363-371.
50. McGivney W.T., Crooks G.M. The care of patients with severe chronic pain in terminal illness. J. Am. Med. Assoc. 251:1984;1182-1188.
51. McLachlan E.M., Jänig W., Devor M., Michaelis M. Peripheral nerve injury triggers noradrenergic sprouting within dorsal root ganglia. Nature. 363:1993;543-546.
52. Medina J.I., Diamond S. Drug dependency in patients with chronic headache. Headache. 17:1977;12-14.
53. Merskey, H., Lindblom, U., Mumford, J.M., Nathan, P.W. and Sunderland Sir, S., Pain terms. In: H. Merskey and N. Bogduk (Eds.), Classification of chronic pain, IASP Press, Seatle, WA, 1994, pp. 207-213.
54. Morley J.S., Watt J.W.G., Wells J.C., Miles J.B., Finnegan M.J., Leng J. Methadone in pain uncontrolled by morphine. Lancet. 342:1993;1243.
55. Moulin D.E., Iezzy A., Amireh R., Sharpe W.K.J., Boyd D., Merskey H. Randomised trial of oral morphine for chronic non-cancer pain. Lancet. 347:1996;143-147.
56. Pagni, C.A., Central pain due to spinal cord and brainstem damage. In: P.D. Wall and R. Melzack (Eds.), Textbook of Pain, Churchill Livingstone, Edinburgh, 1984, pp. 481-496.
57. Plummer J.L., Gourlay G.K., Cherry D.A., Cousins M.J. Estimation of methadone clearance: application in the management of cancer pain. Pain. 33:1988;313-322.
58. Portenoy R.K., Foley K.M. Chronic use of opioid analgesics in non-malignant pain: Report of 38 cases. Pain. 25:1986;171-186.
59. Portenoy R.K. The pharmalogical management of cancer pain. J. Psychosoc. Oncol. 8:1990;75-107.
60. Portenoy R.K., Foley K.M., Inturissi C.E. The nature of opioid responsiveness and its implications for neuropathic pain: new hypotheses derived from studies of opioid infusions. Pain. 43:1990;273-286.
61. Portenoy, R.K., Opioid tolerance and responsiveness: research findings and clinical observations. In: G.F. Gebhart, D.L. Hammond and T.S. Jensen (Eds.), Proceedings of the 7th World Congress on Pain, Progress in Pain Research and Management, Vol. 2, IASP Press, Seatle, WA, 1994, pp. 595-619.
62. Portenoy, R.K., Neuropathic pain. In: R.K. Portenoy and R.M. Kanner (Eds.), Pain Management: Theory and Practice, FA Davis Company, Philadelphia, 1996, pp. 83-125.
63. Porter J., Jick H. Addiction rare in patients treated with narcotics. N Engl. J. Med. 302:1980;123.
64. Price D.D., Harkins S.W., Rafi A., Price C. A simultaneous comparison of fentanyl's analgesic effects on experimental and clinical pain. Pain. 24:1986;197-203.
65. Puke M.J., Wiesenfeld-Hallin Z. The differential effects of morphine and the alpha 2-adrenoreceptor agonists clonidine and dexmedetomidine on the prevention and treatment of experimental neuropathic pain. Anesth. Analg. 77:1993;104-109.
66. Roberts W. A hypothesis on the physiological basis for causalgia and related pains. Pain. 24:1986;297-311.
67. Rodin B.E., Kruger L. Deafferentation in animals as a model for the study of chronic pain: an alternative hypothesis. Brain Res. Rev. 7:1984;213-228.
68. Rowbotham M.C., Reisner-Keller L.A., Fields H.L. Both intravenous lidocaine and morphine reduce the pain of postherpetic neuralgia. Neurology. 41:1991;1024-1028.
69. Seltzer Z., Dubner R., Shir Y. A novel behavioral model of neuropathic pain disorders produced in rats by partial sciatic nerve injury. Pain. 43:1990;205-218.
70. Stanfa L.C., Sullivan A.F., Dickenson A.H. Alterations in neuronal excitability and the potency of spinal mu, delta and kappa opioids after carrageenan-induced inflammation. Pain. 50:1992;345-354.
71. Tasker, R.R., Tsuda, T. and Hawrylyshyn, P., Clinical neurophysiological investigation of deafferentation pain. In: J.J. Bonica, U. Lindblom and A. Iggo (Eds.), Advances in Pain Research and Therapy, Vol. 5, Proceedings 3rd World Congress on Pain, Raven Press, New York, 1983, pp. 713-738.
72. Tasker, R.R. and Dostrovsky, J.O., Deafferentation and central pain. In: P.D. Wall and R. Melzack (Eds.), Textbook of Pain, Vol. 2, Churchill Livingstone, Edinburgh, 1989, pp. 154-180.
73. Tasker, R.R., Management of nociceptive, deafferentation and central pain by surgical intervention. In: H.L. Fields (Ed.), Pain Syndromes in Neurology, Butterworth, London, 1990, pp. 143-200.
74. Taub, A., Opioid analgesics in the treatment of chronic intractable pain of non-neoplastic origin. In: L.M. Kitahata and D. Collins (Eds.), Narcotic Analgesics in Anesthesiology, Williams and Wilkins, Baltimore, 1982, pp. 199-208.
75. Twycross R.G. Opioid analgesics in cancer pain: current practice and controversies. Cancer Surv. 7:1988;29-53.
76. Urban B.J., France R.D., Steinberger E.K., Scott D.L., Maltbie A.A. Long-term use of narcotic/antidepressant medication in the management of phantom limb pain. Pain. 24:1986;191-196.
77. Vainio A., Tigerstedt I. Opioid treatment for radiating cancer pain: oral administration vs. epidural techniques. Acta Anaesthesiol. Scand. 32:1988;179-185.
78. Vecht Ch.J. Nociceptive nerve pain and neuropathic pain. Pain. 39:1989;243-244.
79. Vecht Ch.J., Van de Brand H.J., Wajer O.J.M. Post-axillary dissection pain in breast cancer due to a lesion of the intercostobrachial nerve. Pain. 38:1989;171-176.
80. Wan Lu, C., Urban, B. and France, R.D., Long-term narcotic therapy in chronic pain, Canadian Pain Society and American Pain Society Joined Meeting, 1988, pp. 10-13.
81. Watson C.P.N., Babul N. Efficacy of oxycodone in neuropathic pain. a randomized trial in postherpetic neuralgia. Neurology. 50:1998;1837-1841.
82. Winkelmüller M., Winkelmüller W. Long-term effects of continuous intrathecal opioid treatment in chronic pain of non-malignant etiology. J. Neurosurg. 85:1996;458-467.
83. Woolf C.J., Shortland P.J., Coggeshall R.E. Peripheral nerve injury triggers central sprouting of myelinated afferents. Nature. 355:1992;75-78.
84. Xu X.-J., Hao J.-X., Aldskogius H., Seiger Å., Wiesenfeld-Hallin Z. Chronic pain-related syndrome in rats after ischemic spinal cord lesion: a possible animal model for pain in patients with spinal cord injury. Pain. 48:1992;279-290.
85. Xu X.-J., Puke M.J.C., Verge V.M.K., Wiesenfeld-Hallin Z., Hughes J., Hokfelt T. Upregulation of cholecystokinin in primary sensory neurons is associated with morphine insensitivity in experimental pain in the rat. Neurosci. Lett. 152:1993;129-132.
86. Xu X.-J., Wiesenfeld-Hallin Z. The threshold for the depressive effect of intrathecal morphine on the spinal nociceptive flexor reflex is increased during autotomy after sciatic nerve section in rats. Pain. 46:1991;223-229.
87. Yaksh T.L. Behavioural and autonomic correlates of tactile evoked allodynia produced by spinal glycine inhibition: effect of modulatory receptor systems and excitatory amino acid antagonists. Pain. 37:1989;111-123.
88. Yamamoto T., Mizuguchi T. Time-dependent effects of oral morphine on autotomy following brachial nerve section in the rat. Neurosci. Lett. 141:1992;166-168.
89. Yu W., Hao J.-X., Xu X.-J., Wiesenfeld-Hallin Z. Comparison of the anti-allodynic and antinociceptive effects of systemic, intrathecal, and intracerebroventricular morphine in a rat model of central neuropathic pain. Eur. J. Pain. 1:1997;17-29.
90. Zenz M., Strumpf M., Tryba M. Long-term opioid therapy in patients with chronic non-malignant pain. J. Pain Symptom Manage. 7:1992;69-72.