Synthesis of new 4-heteroaryl-2-phenylquinolines and their pharmacological activity as NK-2/NK-3 receptor ligands

Archiv der Pharmazie

Volumn 340, Issue 1, 2007, Pages 17-25

  Borioni, Anna ^a   Mustazza, Carlo ^a   Sestili, Isabella ^a   Sbraccia, Maria ^a   Turchetto, Luciana ^a   Del Giudice, Maria Rosaria ^a  

^a ISTITUTO SUPERIORE DI SANITÀ   (Italy)

Author keywords

4 Heteroaryl 2 phenylquinolines; Neurokinin receptors; NK 2; NK 3

Indexed keywords

2 PHENYL 4 (1 PHENYL[1,2,4]TRIAZOL 5 YL)QUINOLINE; 2 PHENYL 4 (2 PHENYLIMIDAZOL 4 YL)QUINOLINE; 2 PHENYL 4 (2 PHNEYLIMIDAZOL 4 YL)QUINOLINE; 2 PHENYL 4 (3 PHENYL[1,2,4]TRIAZOL 5 YL)QUINOLINE; 2 PHENYL 4 (4 PHENYLIMIDAZOL 2 YL)QUINOLINE; 2 PHENYL 4 (4 PHENYLOXAZOL 2 YL)QUINOLINE; 2 PHENYL 4 (5 PHENYL[1,2,4]TRIAZOL 3 YL)QUINOLINE; 2 PHENYL 4 (5 PHENYLPYRAZOL 3 YL)QUINOLINE; 2 PHENYL 4 (PYRAZOL 3 YL)QUINOLINE; 2 PHENYL 4 [1 (PHENYLAMINOMETHYL)PYRAZOL 3 YL]QUINOLINE; 2 PHENYLCARBOXAMIDE DERIVATIVE; 4 (3 AMINO[1,2,4]TRIAZOL 5 YL) 2 PHENYLQUINOLINE; 4 (3 AMINOPYRAZOL 5 YL) 2 PHENYLQUINOLINE; 4 (3 BENZOYLAMINOPYRAZOL 5 YL) 2 PHENYLQUINOLINE; 4 (3 BENZYLAMINO[1,2,4]TRIAZOL 5 YL) 2 PHENYLQUINOLINE; 4 (3 BENZYLAMINOPYRAZOL 5 YL) 2 PHENYLQUINOLINE; 4 (5 AMINO[1,2,4]TRIAZOL 3 YL) 2 PHENYLQUINOLINE; 4 (BENZOYLACETYL) 2 PHENYLQUINOLINE; 4 (CYANACETYL) 2 PHENYLQUINOLINE; 4 [1 (3 FLUOROPHENYLAMINOMETHYL)PYRAZOL 3 YL] 2 PHENYLQUINOLINE; 4 [3 (1 PHENYLPROPYL)AMINOPYRAZOL 5 YL] 2 PHENYLQUINOLINE; 4 [3 (3 THIENYLMETHYL)AMINOPYRAZOL 5 YL] 2 PHENYLQUINOLINE; N [ALPHA (METHOXYCARBONYL)BENZYL] 2 PHENYL 4 QUINOLINECARBOXAMIDE; NEUROKININ 2 RECEPTOR; NEUROKININ 3 RECEPTOR; NEUROKININ 3 RECEPTOR ANTAGONIST; PHENACYL 2 PHENYL 4 QUINOLINECARBOXYLIC ACID; PHENYLQUINONE; QUINOLINE DERIVATIVE; UNCLASSIFIED DRUG;

ARTICLE; BINDING AFFINITY; DRUG ACTIVITY; DRUG RECEPTOR BINDING; DRUG SYNTHESIS; HYDROGEN BOND; ISOMERISM; NUCLEAR MAGNETIC RESONANCE; PRIORITY JOURNAL; STRUCTURE ACTIVITY RELATION;

ANIMALS; BINDING, COMPETITIVE; CHO CELLS; CRICETINAE; CRICETULUS; FEASIBILITY STUDIES; HUMANS; LIGANDS; MAGNETIC RESONANCE SPECTROSCOPY; MASS SPECTROMETRY; MOLECULAR STRUCTURE; QUINOLINES; RECEPTORS, NEUROKININ-2; RECEPTORS, NEUROKININ-3; STRUCTURE-ACTIVITY RELATIONSHIP; TRANSFECTION;

EID: 33846467819     PISSN: 03656233     EISSN: 15214184     Source Type: Journal    
DOI: 10.1002/ardp.200600113     Document Type: Article

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