2-phenyl-4-quinolinecarboxamides: A novel class of potent and selective non-peptide competitive antagonists for the human neurokinin-3 receptor

Journal of Medicinal Chemistry

Volumn 39, Issue 12, 1996, Pages 2281-2284

  Giardina, Giuseppe A M ^a   Sarau, Henry M ^b   Farina, Carlo ^a   Medhurst, Andrew D ^b   Grugni, Mario ^a   Foley, James J ^b   Raveglia, Luca F ^a   Schmidt, Dulcie B ^b   Rigolio, Roberto ^a   Vassallo, Marco ^a   Vecchietti, Vittorio ^a   Hay, Douglas W P ^b  

^a SmithKline Beecham SpA   (Italy)

^b GLAXOSMITHKLINE   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

NEUROKININ; NEUROKININ 3 RECEPTOR; OSANETANT; RECEPTOR SUBTYPE; SAREDUTANT; TACHYKININ RECEPTOR ANTAGONIST;

ANIMAL CELL; ARTICLE; DRUG POTENCY; DRUG RECEPTOR BINDING; NEUROLOGIC DISEASE; NEUROMODULATION; NONHUMAN; RECEPTOR AFFINITY;

ANIMALS; BINDING, COMPETITIVE; CHO CELLS; CILIARY BODY; CRICETINAE; CRICETULUS; DRUG DESIGN; GUINEA PIGS; HUMANS; MUSCLE CONTRACTION; PEPTIDE FRAGMENTS; PIPERIDINES; QUINOLINES; RABBITS; RECEPTORS, NEUROKININ-3; RECOMBINANT FUSION PROTEINS; STRUCTURE-ACTIVITY RELATIONSHIP; SUBSTANCE P;

EID: 5244332801     PISSN: 00222623     EISSN: None     Source Type: Journal    
DOI: 10.1021/jm9602423     Document Type: Article

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