Immunology research: Challenges and opportunities in a time of budgetary constraint

Nature Immunology

Volumn 8, Issue 2, 2007, Pages 114-117

  Hackett, Charles J ^a   Rotrosen, Daniel ^a   Auchincloss, Hugh ^a   Fauci, Anthony S ^a  

^a NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

B LYMPHOCYTE RECEPTOR; INFLUENZA VACCINE; INTERFERON; MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 2; POLIOMYELITIS VACCINE; TOLL LIKE RECEPTOR; TOLL LIKE RECEPTOR 4; VIRUS RNA;

ACQUIRED IMMUNE DEFICIENCY SYNDROME; ARTICLE; B LYMPHOCYTE; BIOLOGICAL WARFARE; BUDGET; COST CONTROL; FINANCIAL MANAGEMENT; GENETIC REGULATION; GENOME ANALYSIS; GOVERNMENT; HEALTH CARE ORGANIZATION; HEALTH PROGRAM; HUMAN; HUMAN GENOME; HUMAN IMMUNODEFICIENCY VIRUS; IMMUNE RESPONSE; IMMUNOGENICITY; IMMUNOLOGICAL TOLERANCE; IMMUNOLOGY; INFECTION; INFLUENZA; INNATE IMMUNITY; MEDICAL EDUCATION; MEDICAL RESEARCH; MEDICAL SOCIETY; MICROBIOLOGY; POLIOMYELITIS; PRIORITY JOURNAL; ROTAVIRUS; T LYMPHOCYTE; WART VIRUS;

ALLERGY AND IMMUNOLOGY; BIOMEDICAL RESEARCH; BUDGETS; HUMANS; NATIONAL INSTITUTES OF HEALTH (U.S.); TIME FACTORS; UNITED STATES;

EID: 33846466719     PISSN: 15292908     EISSN: 15292916     Source Type: Journal    
DOI: 10.1038/ni0207-114     Document Type: Article

References (28)

1. Bishop, J.M. & Varmus, H. Science 312, 499 (2006).
2. International Human Genome Sequencing. C. Nature 431, 931-945 (2004).
3. Beutler, B. et al. Annu. Rev. Immunol. 24, 353-389 (2006).
4. Meylan, E. & Tschopp, J. Mol. Cell 22, 561-569 (2006).
5. Janeway, C.A., Jr., Travers, P., Walport, M. & Shlomchik, M. Immunobiology: The Immune System in Health and Disease 6th edn. 135-165 (Garland Science Publishing, New York, 2005).
6. Clark, R.H., Kenyon, J.C., Bartlett, N.W., Tscharke, D.C. & Smith, G.L. J. Gen. Virol. 87, 29-38 (2006).
7. McMichael, A.J. et al. Eur. J. Immunol. 9, 205-210 (1979).
8. Beckman, E.M. et al. Nature 372, 691-694 (1994).
9. Isaacs, A. & Lindenmann, J. Proc. R. Soc. Lond. B 147, 258-267 (1957).
10. Gitlin, L. et al. Proc. Natl. Acad. Sci. USA 103, 8459-8464 (2006).
11. Hornung, V. et al. Science 314, 935-936 (2006).
12. Pichlmair, A. et al. Science 314, 997-1001 (2006).
13. Janeway, C.A., Jr. Cold Spring Harb. Symp. Quant. Biol. 54, 1-13 (1989).
14. Lindblad, E.B. Vaccine 22, 3658-3668 (2004).15.
15. Pulendran, B. & Ahmed, R. Cell 124, 849-863 (2006).
16. Anderson, M.S. et al. Immunity 23, 227-239 (2005).
17. Fontenot, J.D. & Rudensky, A.Y. Nat. Immunol. 6, 331-337 (2005).
18. Gill, S.R. et al. Science 312, 1355-1359 (2006).
19. Lefrancois, L. & Puddington, L. Annu. Rev. Immunol. 24, 681-704 (2006).
20. Fischer, H., Yamamoto, M., Akira, S., Beutler, B. & Svanborg, C. Eur. J. Immunol. 36, 267-277 (2006).
21. Uematsu, S. et al. Nat. Immunol. 7, 868-874 (2006).
22. Rakoff-Nahoum, S., Paglino, J., Eslami-Varzaneh, F., Edberg, S. & Medzhitov, R. Cell 118, 229-241 (2004).
23. Mazmanian, S.K., Liu, C.H., Tzianabos, A.O. & Kasper, D.L. Cell 122, 107-118 (2005).
24. Treml, L.S., Crowley, J.E. & Cancro, M.P. Semin. Immunol. 18, 297-304 (2006).
25. Ruprecht, C.R. & Lanzavecchia, A. Eur. J. Immunol. 36, 810-816 (2006).
26. Begley, S. Wall Street Journal A11 (1 September 2006).
27. Bernasek, A. The New York Times Section 3, p.3 (3 September 2006).
28. Fauci, A.S. Lancet 348, 1002-1003 (1996).