Engineering of the spinosyn PKS: Directing starter unit incorporation

Journal of Natural Products

Volumn 69, Issue 12, 2006, Pages 1702-1710

  Sheehan, Lesley S ^a   Lill, Rachel E ^a   Wilkinson, Barrie ^a   Sheridan, Rose M ^a   Vousden, William A ^a   Kaja, Andrew L ^a   Crouse, Gary D ^b   Gifford, James ^b   Graupner, Paul R ^b   Karr, Laura ^b   Lewer, Paul ^b   Sparks, Thomas C ^b   Leadlay, Peter F ^c   Waldron, Clive ^b   Martin, Christine J ^a  

^a BIOTICA TECHNOLOGY LTD   (United Kingdom)

^b DOW AGROSCIENCES LLC   (United States)

^c UNIVERSITY OF CAMBRIDGE   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

21 DESETHYL 21 (2 FURANYL)SPINOSYN D; 21 DESETHYL 21 (CYANOMETHYL)SPINOSYN A; 21 DESETHYL 21 (CYANOMETHYL)SPINOSYN D; 21 DESETHYL 21 (CYCLOBUTYL)SPINOSYN A; 21 DESETHYL 21 (CYCLOBUTYL)SPINOSYN D; 21 DESETHYL 21 (CYCLOPROPYL)SPINOSYN A; 21 DESETHYL 21 (CYCLOPROPYL)SPINOSYN D; 21 DESETHYL 21 (ISOPROPYL)SPINOSYN A; 21 DESETHYL 21 (ISOPROPYL)SPINOSYN D; 21 DESETHYL 21 (METHYLTHIOMETHYL)SPINOSYN A; 21 DESETHYL 21 (METHYLTHIOMETHYL)SPINOSYN D; 21 DESETHYL 21 (N PROPYL)SPINOSYN A; 21 DESETHYL 21 (SEC BUTYL)SPINOSYN A; 21 DESETHYL 21 (SEC BUTYL)SPINOSYN D; AVERMECTIN; CARBOXYLIC ACID; ERYTHROMYCIN; INSECTICIDE; MACROLIDE; POLYKETIDE SYNTHASE; SPINOSYN; SPINOSYN A; SPINOSYN D; SPINOSYN E; UNCLASSIFIED DRUG;

ARTICLE; BACTERIAL STRAIN; DRUG IDENTIFICATION; DRUG ISOLATION; GENETIC ENGINEERING; INSECTICIDAL ACTIVITY; NUCLEOTIDE SEQUENCE; SACCHAROPOLYSPORA; STREPTOMYCES; STRUCTURE ACTIVITY RELATION;

AMINO ACID SEQUENCE; ANIMALS; BASE SEQUENCE; DNA; ERYTHROMYCIN; ESCHERICHIA COLI; INSECTICIDES; IVERMECTIN; MACROLIDES; MODELS, MOLECULAR; POLYKETIDE SYNTHASES; PROTEIN ENGINEERING; SACCHAROPOLYSPORA; STREPTOMYCES; TETRANYCHIDAE;

HEXAPODA; SACCHAROPOLYSPORA ERYTHRAEA; STREPTOMYCES AVERMITILIS;

EID: 33846453972     PISSN: 01633864     EISSN: None     Source Type: Journal    
DOI: 10.1021/np0602517     Document Type: Article

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