In vivo identification and manipulation of the Ca2+ selectivity filter in the Drosophila transient receptor potential channel

Journal of Neuroscience

Volumn 27, Issue 3, 2007, Pages 604-615

  Liu, Che H ^a   Wang, Tao ^b   Postma, Marten ^a   Obukhov, Alexander G ^c   Montell, Craig ^b   Hardie, Roger C ^a  

^a UNIVERSITY OF CAMBRIDGE   (United Kingdom)

^b JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c INDIANA UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Calcium channel; Permeability; Photoreceptor; Pore; Retinal degeneration; TRP channels; TRPC

Indexed keywords

CALCIUM; CALCIUM CHANNEL; MUTANT PROTEIN; PROTEIN SUBUNIT; TRANSIENT RECEPTOR POTENTIAL CHANNEL;

ANIMAL CELL; ARTICLE; CALCIUM TRANSPORT; CELL SURVIVAL; DROSOPHILA; NONHUMAN; PHOTORECEPTOR; PRIORITY JOURNAL; PROTEIN FUNCTION; PROTEIN LOCALIZATION; RETINA DEGENERATION;

AMINO ACID SEQUENCE; ANIMALS; ANIMALS, GENETICALLY MODIFIED; ASPARTIC ACID; CALCIUM; CALCIUM CHANNELS; DROSOPHILA MELANOGASTER; DROSOPHILA PROTEINS; MOLECULAR SEQUENCE DATA; MUTATION; PHOTORECEPTORS, INVERTEBRATE; RETINAL DEGENERATION; TRANSIENT RECEPTOR POTENTIAL CHANNELS;

EID: 33846451767     PISSN: 02706474     EISSN: 02706474     Source Type: Journal    
DOI: 10.1523/JNEUROSCI.4099-06.2007     Document Type: Article

References (57)

1. Agam K, von Campenhausen M, Levy S, Ben-Ami HC, Cook B, Kirschfeld K, Minke B (2000) Metabolic stress reversibly activates the Drosophila light- sensitive channels TRP and TRPL in vivo. J Neurosci 20:5748-5755.
2. Chenna R, Sugawara H, Koike T, Lopez R, Gibson TJ, Higgins DG, Thompson JD (2003) Multiple sequence alignment with the Clustal series of programs. Nucleic Acids Res 31:3497-3500.
3. Chevesich J, Kreuz AJ, Montell C (1997) Requirement for the PDZ domain protein, INAD, for localization of the TRP store-operated channel to a signaling complex. Neuron 18:95-105.
4. Cook B, Minke B (1999) TRP and calcium stores in Drosophila phototransduction. Cell Calcium 25:161-171.
5. Cosens DJ, Manning A (1969) Abnormal electroretinogram from a Drosophila mutant. Nature 224:285-287.
6. Dietrich A, Kalwa H, Rost BR, Gudermann T (2005) The diacylgylcerol- sensitive TRPC3/6/7 subfamily of cation channels: functional characterization and physiological relevance. Pflügers Arch 451:72-80.
7. + conduction and selectivity. Science 280:69-77.
8. Dwyer TM, Adams DJ, Hille B (1980) The permeability of the endplate channel to organic cations in frog muscle. J Gen Physiol 75:469-492.
9. 2+ blockage, and ionic selectivity. Proc Natl Acad Sci USA 91:1109-1113.
10. Franceschini N, Kirschfeld K (1971) Etude optique in vivo des elements photorecepteurs dans l'oeil compose de Drosophila. Kybernetik 9:159-182.
11. Garcia-Martinez C, Morenilla-Palao C, Planells-Cases R, Merino JM, Ferrer-Montiel A (2000) Identification of an aspartic residue in the P-loop of the vanilloid receptor that modulates pore properties. J Biol Chem 275:32552-32558.
12. Hardie RC (1991) Whole-cell recordings of the light-induced current in Drosophila photoreceptors: evidence for feedback by calcium permeating the light sensitive channels. Proc R Soc Lond B Biol Sci 245:203-210.
13. 2+ facilitates and inactivates but does not directly excite light-sensitive channels in Drosophila photoreceptors. J Neurosci 15:889-902.
14. 2+ channel in Drosophila photoreceptors. Neuron 8:643-651.
15. Hardie RC, Minke B (1994) Spontaneous activation of light-sensitive channels in Drosophila photoreceptors. J Gen Physiol 103:389-407.
16. Hardie RC, Mojet MH (1995) Magnesiumdependent block of the light-activated and trp-dependent conductance in Drosophila photoreceptors. J Neurophysiol 74:2590-2599.
17. Hardie RC, Raghu P (2001) Visual transduction in Drosophila. Nature 413:186-193.
18. 2 levels in Drosophila photoreceptors. Neuron 30:149-159.
19. P24, by the diacylglycerol kinase mutant, rdgA, and by metabolic inhibition. J Biol Chem 278:18851-18858.
20. Hardie RC, Gu Y, Martin F, Sweeney ST, Raghu P (2004) In vivo light-induced and basal phospholipase C activity in Drosophila photoreceptors measured with genetically targeted phosphatidylinositol 4,5-bisphosphate-sensitive ion channels (Kir2.1). J Biol Chem 279:47773-47782.
21. 2+. J Physiol (Lond) 524:179-194.
22. 2+ channel essential for phosphoinositide-mediated photoreception, forms a signaling complex with NorpA, InaC and InaD. EMBO J 15:7036-7045.
23. Jung S, Muhle A, Schaefer M, Strotmann R, Schultz G, Plant TD (2003) Lanthanides potentiate TRPC5 currents by an action at extracellular sites close to the pore mouth. J Biol Chem 278:3562-3571.
24. HS, Montell C (2000) TRP and the PDZ Protein, INAD, form the core complex required for retention of the signalplex in Drosophila photoreceptor cells. J Cell Biol 150:1411-1422.
25. 2+ channels. Role of acidic amino acid residues in the S5-S6 region. J Biol Chem 278:11337-11343.
26. McGuffin LJ, Bryson K, Jones DT (2000) The PSIPRED protein structure prediction server. Bioinformatics 16:404-405.
27. Minke B, Wu C-F, Pak WL (1975) Induction of photoreceptor noise in the dark in a Drosophila mutant. Nature 258:84-87.
28. Montell C (1999) Visual transduction in Drosophila. Annu Rev Cell Dev Biol 15:231-268.
29. Montell C (2005) The TRP superfamily of cation channels. Sci STKE 2005:re3.
30. Montell C, Rubin GM (1989) Molecular characterization of Drosophila trp locus, a putative integral membrane protein required for phototransduction. Neuron 2:1313-1323.
31. Montell C, Jones K, Hafen E, Rubin G (1985) Rescue of the Drosophila phototransduction mutation trp by germline transformation. Science 230:1040-1043.
32. Niemeyer BA, Suzuki E, Scott K, Jalink K, Zuker CS (1996) The Drosophila light-activated conductance is composed of the two channels TRP and TRPL. Cell 85:651-659.
33. 2+ channel. J Biol Chem 276:1020-1025.
34. 2+ block and regulates inward current amplitude of a transient receptor potential channel. J Neurosci 25:1234-1239.
35. Owsianik G, Talavera K, Voets T, Nilius B (2006) Permeation and selectivity of TRP channels. Annu Rev Physiol 68:685-717.
36. Phillips AM, Bull A, Kelly LE (1992) Identification of a Drosophila gene encoding a calmodulin-binding protein with homology to the trp phototransduction gene. Neuron 8:631-642.
37. 2+-permeable nonselective cation channels. Cell Calcium 33:441-450.
38. Raghu P, Usher K, Jonas S, Chyb S, Polyanovsky A, Hardie RC (2000) Constitutive activity of the light-sensitive channels TRP and TRPL in the Drosophila diacylglycerol kinase mutant, rdgA. Neuron 26:169-179.
39. Ramsey IS, Delling M, Clapham DE (2006) An introduction to TRP channels. Annu Rev Physiol 68:619-647.
40. Ranganathan R, Harris GL, Stevens CF, Zuker CS (1991) A Drosophila mutant defective in extracellular calcium-dependent photoreceptor deactivation and rapid desensitization. Nature 354:230-232.
41. Reuss H, Mojet MH, Chyb S, Hardie RC (1997) In vivo analysis of the Drosophila light-sensitive channels, TRP and TRPL. Neuron 19:1249-1259.
42. Scott K, Sun YM, Beckingham K, Zuker CS (1997) Calmodulin regulation of Drosophila light-activated channels and receptor function mediates termination of the light response in vivo. Cell 91:375-383.
43. +-conducting channel. Nature 440:570-574.
44. 2+ channel by INAD in Drosophila photoreceptors. Neuron 16:991-998.
45. Tsunoda S, Sierralta J, Sun YM, Bodner R, Suzuki E, Becker A, Socolich M, Zuker CS (1997) A multivalent PDZ-domain protein assembles signalling complexes in a G-protein-coupled cascade. Nature 388:243-249.
46. Tsunoda S, Sun Y, Suzuki E, Zuker C (2001) Independent anchoring and assembly mechanisms of INAD signaling complexes in Drosophila photoreceptors. J Neurosci 21:150-158.
47. Vaca L, Sinkins WG, Hu Y, Kunze DL, Schilling WP (1994) Activation of recombinant trp by thapsigargin in Sf9 insect cells. Am J Physiol 267:C1501-C1505.
48. Voets T, Prenen J, Vriens J, Watanabe H, Janssens A, Wissenbach U, Bodding M, Droogmans G, Nilius B (2002) Molecular determinants of permeation through the cation channel TRPV4. J Biol Chem 277:33704-33710.
49. 2+-selective TRP channel. J Biol Chem 279:15223-15230.
50. Wang T, Jiao Y, Montell C (2005) Dissecting independent channel and scaffolding roles of the Drosophila transient receptor potential channel. J Cell Biol 171:685-694.
51. Wes PD, Chevesich J, Jeromin A, Rosenberg C, Stetten G, Montell C (1995) TRPC1, a human homolog of a Drosophila store-operated channel. Proc Natl Acad Sci USA 92:9652-9656.
52. Wes PD, Xu XZ, Li HS, Chien F, Doberstein SK, Montell C (1999) Termination of phototransduction requires binding of the NINAC myosin III and the PDZ protein INAD. Nat Neurosci 2:447-453.
53. Xu XZS, Li HS, Guggino WB, Montell C (1997) Coassembly of TRP and TRPL produces a distinct store-operated conductance. Cell 89:1155-1164.
54. Xu XZS, Choudhury A, Li XL, Montell C (1998) Coordination of an array of signaling proteins through homo- and heteromeric interactions between PDZ domains and target proteins. J Cell Biol 142:545-555.
55. 2+ channels. Nature 366:158-161.
56. Yu FH, Yarov-Yarovoy V, Gutman GA, Catterall WA (2005) Overview of molecular relationships in the voltage-gated ion channel superfamily. Pharmacol Rev 57:387-395.
57. Zhu X, Chu PB, Peyton M, Birnbaumer L (1995) Molecular cloning of a widely expressed human homologue for the Drosophila trp gene. FEBS Lett 373:193-198.