A cytosolic residue mediates Mg2+ block and regulates inward current amplitude of a transient receptor potential channel

Journal of Neuroscience

Volumn 25, Issue 5, 2005, Pages 1234-1239

  Obukhov, Alexander G ^a   Nowycky, Martha C ^a  

^a RUTGERS NEW JERSEY MEDICAL SCHOOL   (United States)

Author keywords

Calcium influx; Cation channels; Cell excitability; Inward currents; Inward rectification; Mg2+ block; TRP channels

Indexed keywords

ASPARTIC ACID; CATION; CATION CHANNEL; MAGNESIUM; TRANSIENT RECEPTOR POTENTIAL CHANNEL;

AMINO ACID SUBSTITUTION; AMPLITUDE MODULATION; ARTICLE; CALCIUM TRANSPORT; CELL FUNCTION; CONDUCTANCE; CONTROLLED STUDY; CYTOSOL; ELECTRIC POTENTIAL; ELECTRICITY; EXCITABILITY; HIPPOCAMPUS; HUMAN; HUMAN CELL; NERVE CELL; NEURITE; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN EXPRESSION; PROTEIN FUNCTION;

AMINO ACID SUBSTITUTION; ANIMALS; ASPARTIC ACID; CALCIUM CHANNELS; CATION TRANSPORT PROTEINS; CELL LINE; DIMERIZATION; HISTAMINE; HUMANS; ION TRANSPORT; MAGNESIUM; MICE; MODELS, CHEMICAL; PATCH-CLAMP TECHNIQUES; PROTEIN CONFORMATION; PROTEIN HYBRIDIZATION; RATS; RECOMBINANT FUSION PROTEINS; STRUCTURE-ACTIVITY RELATIONSHIP; TRANSFECTION; TRPC CATION CHANNELS;

EID: 13944262457     PISSN: 02706474     EISSN: None     Source Type: Journal    
DOI: 10.1523/JNEUROSCI.4451-04.2005     Document Type: Article

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