-
1
-
-
0037371578
-
Selective tryptic cleavage at the tethered ligand site of the amino terminal domain of proteinase-activated receptor-2 in intact cells
-
Al-Ani B and Hollenberg MD (2003) Selective tryptic cleavage at the tethered ligand site of the amino terminal domain of proteinase-activated receptor-2 in intact cells. J Pharmacol Exp Ther 304:1120-1128.
-
(2003)
J Pharmacol Exp Ther
, vol.304
, pp. 1120-1128
-
-
Al-Ani, B.1
Hollenberg, M.D.2
-
2
-
-
0032712580
-
Proteinase activated receptor 2: Role of extracellular loop 2 for ligand-mediated activation
-
Al-Ani B, Saifeddine M, Kawabata A, and Hollenberg MD (1999) Proteinase activated receptor 2: Role of extracellular loop 2 for ligand-mediated activation. Br J Pharmacol 128:1105-1113.
-
(1999)
Br J Pharmacol
, vol.128
, pp. 1105-1113
-
-
Al-Ani, B.1
Saifeddine, M.2
Kawabata, A.3
Hollenberg, M.D.4
-
3
-
-
0035145180
-
Muscarinic acetylcholine receptor antibodies as a new marker of dry eye Sjogren syndrome
-
Bacman S, Berra A, Sterin-Borda L, and Borda E (2001) Muscarinic acetylcholine receptor antibodies as a new marker of dry eye Sjogren syndrome. Investig Ophthalmol Vis Sci 42:321-327.
-
(2001)
Investig Ophthalmol Vis Sci
, vol.42
, pp. 321-327
-
-
Bacman, S.1
Berra, A.2
Sterin-Borda, L.3
Borda, E.4
-
4
-
-
2442700125
-
Regulation of angiogenesis by tissue factor cytoplasmic domain signaling
-
Belting M, Dorrell MI, Sandgren S, Aguilar E, Ahamed J, Dorfleutner A, Carmeliet P, Mueller BM, Friedlander M, and Ruf W (2004) Regulation of angiogenesis by tissue factor cytoplasmic domain signaling. Nat Med 10:502-509.
-
(2004)
Nat Med
, vol.10
, pp. 502-509
-
-
Belting, M.1
Dorrell, M.I.2
Sandgren, S.3
Aguilar, E.4
Ahamed, J.5
Dorfleutner, A.6
Carmeliet, P.7
Mueller, B.M.8
Friedlander, M.9
Ruf, W.10
-
5
-
-
0032090264
-
Xerostomia. A common problem among the elderly
-
Bivona PL (1998) Xerostomia. A common problem among the elderly. NY State Dent J 64:46-52.
-
(1998)
NY State Dent J
, vol.64
, pp. 46-52
-
-
Bivona, P.L.1
-
7
-
-
1842414265
-
Mast cell tryptase regulates rat colonic myocytes through proteinase-activated receptor 2
-
Corvera CU, Dery O, McConalogue K, Bohm SK, Khitin LM, Caughey GH, Payan DG, and Bunnett NW (1997) Mast cell tryptase regulates rat colonic myocytes through proteinase-activated receptor 2. J Clin Investig 100:1383-1393.
-
(1997)
J Clin Investig
, vol.100
, pp. 1383-1393
-
-
Corvera, C.U.1
Dery, O.2
McConalogue, K.3
Bohm, S.K.4
Khitin, L.M.5
Caughey, G.H.6
Payan, D.G.7
Bunnett, N.W.8
-
8
-
-
33646343709
-
Antimuscarinic antibodies in primary Sjogren's syndrome reversibly inhibit the mechanism of fluid secretion by human submandibular salivary acinar cells
-
Dawson LJ, Stanbury J, Venn N, Hasdimir B, Rogers SN, and Smith PM (2006) Antimuscarinic antibodies in primary Sjogren's syndrome reversibly inhibit the mechanism of fluid secretion by human submandibular salivary acinar cells. Arthritis Rheum 54:1165-1173.
-
(2006)
Arthritis Rheum
, vol.54
, pp. 1165-1173
-
-
Dawson, L.J.1
Stanbury, J.2
Venn, N.3
Hasdimir, B.4
Rogers, S.N.5
Smith, P.M.6
-
9
-
-
0031744875
-
Proteinase-activated receptors: Novel mechanisms of signaling by serine proteases
-
Dery O, Corvera CU, Steinhoff M, and Bunnett NW (1998) Proteinase-activated receptors: novel mechanisms of signaling by serine proteases. Am J Physiol 274: C1429-C1452.
-
(1998)
Am J Physiol
, vol.274
-
-
Dery, O.1
Corvera, C.U.2
Steinhoff, M.3
Bunnett, N.W.4
-
10
-
-
0023286847
-
Neuropeptides and secretion
-
Ekstrom J (1987) Neuropeptides and secretion. J Dent Res 66:524-530.
-
(1987)
J Dent Res
, vol.66
, pp. 524-530
-
-
Ekstrom, J.1
-
11
-
-
0037247658
-
Essential role for proteinaseactivated receptor-2 in arthritis
-
Ferrell WR, Lockhart JC, Kelso EB, Dunning L, Plevin R, Meek SE, Smith AJ, Hunter GD, McLean JS, McGarry F, et al. (2003) Essential role for proteinaseactivated receptor-2 in arthritis. J Clin Investig 111:35-41.
-
(2003)
J Clin Investig
, vol.111
, pp. 35-41
-
-
Ferrell, W.R.1
Lockhart, J.C.2
Kelso, E.B.3
Dunning, L.4
Plevin, R.5
Meek, S.E.6
Smith, A.J.7
Hunter, G.D.8
McLean, J.S.9
McGarry, F.10
-
12
-
-
25844462280
-
IP3 receptor types 2 and 3 mediate exocrine secretion underlying energy metabolism
-
Futatsugi A, Nakamura T, Yamada MK, Ebisui E, Nakamura K, Uchida K, Kitaguchi T, Takahashi-Iwanaga H, Noda T, Aruga J, et al. (2005) IP3 receptor types 2 and 3 mediate exocrine secretion underlying energy metabolism. Science (Wash DC) 309:2232-2234.
-
(2005)
Science (Wash DC)
, vol.309
, pp. 2232-2234
-
-
Futatsugi, A.1
Nakamura, T.2
Yamada, M.K.3
Ebisui, E.4
Nakamura, K.5
Uchida, K.6
Kitaguchi, T.7
Takahashi-Iwanaga, H.8
Noda, T.9
Aruga, J.10
-
14
-
-
0027174547
-
Role of the aminoand carboxyl-terminal domains of thrombin receptor-derived polypeptides in biological activity in vascular endothelium and gastric smooth muscle: Evidence for receptor subtypes
-
Hollenberg MD, Laniyonu AA, Saifeddine M, and Moore GJ (1993) Role of the aminoand carboxyl-terminal domains of thrombin receptor-derived polypeptides in biological activity in vascular endothelium and gastric smooth muscle: evidence for receptor subtypes. Mol Pharmacol 43:921-930.
-
(1993)
Mol Pharmacol
, vol.43
, pp. 921-930
-
-
Hollenberg, M.D.1
Laniyonu, A.A.2
Saifeddine, M.3
Moore, G.J.4
-
15
-
-
2442697694
-
Potent and metabolically stable agonists for protease-activated receptor-2: Evaluation of activity in multiple assay systems in vitro and in vivo
-
Kawabata A, Kanke T, Yonezawa D, Ishiki T, Saka M, Kabeya M, Sekiguchi F, Kubo S, Kuroda R, Iwaki M, et al. (2004a) Potent and metabolically stable agonists for protease-activated receptor-2: evaluation of activity in multiple assay systems in vitro and in vivo. J Pharmacol Exp Ther 309:1098-1107.
-
(2004)
J Pharmacol Exp Ther
, vol.309
, pp. 1098-1107
-
-
Kawabata, A.1
Kanke, T.2
Yonezawa, D.3
Ishiki, T.4
Saka, M.5
Kabeya, M.6
Sekiguchi, F.7
Kubo, S.8
Kuroda, R.9
Iwaki, M.10
-
16
-
-
0037031532
-
Role of N-methyl-D-aspartate receptors and the nitric oxide pathway in nociception/hyperalgesia elicited by protease-activated receptor-2 activation in mice and rats
-
Kawabata A, Kawao N, Itoh H, Shimada C, Takebe K, Kuroda R, Masuko T, Kataoka K, and Ogawa S (2002a) Role of N-methyl-D-aspartate receptors and the nitric oxide pathway in nociception/hyperalgesia elicited by protease-activated receptor-2 activation in mice and rats. Neurosci Lett 329:349-353.
-
(2002)
Neurosci Lett
, vol.329
, pp. 349-353
-
-
Kawabata, A.1
Kawao, N.2
Itoh, H.3
Shimada, C.4
Takebe, K.5
Kuroda, R.6
Masuko, T.7
Kataoka, K.8
Ogawa, S.9
-
17
-
-
0034983372
-
The protease-activated receptor-2 agonist induces gastric mucus secretion and mucosal cytoprotection
-
Kawabata A, Kinoshita M, Nishikawa H, Kuroda R, Nishida M, Araki H, Arizono N, Oda Y, and Kakehi K (2001) The protease-activated receptor-2 agonist induces gastric mucus secretion and mucosal cytoprotection. J Clin Investig 107:1443-1450.
-
(2001)
J Clin Investig
, vol.107
, pp. 1443-1450
-
-
Kawabata, A.1
Kinoshita, M.2
Nishikawa, H.3
Kuroda, R.4
Nishida, M.5
Araki, H.6
Arizono, N.7
Oda, Y.8
Kakehi, K.9
-
18
-
-
0034085870
-
Protease-activated receptor (PAR), a novel family of G protein-coupled seven trans-membrane domain receptors: Activation mechanisms and physiological roles
-
Kawabata A and Kuroda R (2000) Protease-activated receptor (PAR), a novel family of G protein-coupled seven trans-membrane domain receptors: activation mechanisms and physiological roles. Jpn J Pharmacol 82:171-174.
-
(2000)
Jpn J Pharmacol
, vol.82
, pp. 171-174
-
-
Kawabata, A.1
Kuroda, R.2
-
19
-
-
0037019916
-
Protease-activated receptor-2 (PAR-2) in the pancreas and parotid gland: Immunolocalization and involvement of nitric oxide in the evoked amylase secretion
-
Kawabata A, Kuroda R, Nishida M, Nagata N, Sakaguchi Y, Kawao N, Nishikawa H, Arizono N, and Kawai K (2002b) Protease-activated receptor-2 (PAR-2) in the pancreas and parotid gland: immunolocalization and involvement of nitric oxide in the evoked amylase secretion. Life Sci 71:2435-2446.
-
(2002)
Life Sci
, vol.71
, pp. 2435-2446
-
-
Kawabata, A.1
Kuroda, R.2
Nishida, M.3
Nagata, N.4
Sakaguchi, Y.5
Kawao, N.6
Nishikawa, H.7
Arizono, N.8
Kawai, K.9
-
20
-
-
0034595060
-
Activation of protease-activated receptor-2 (PAR-2) triggers mucin secretion in the rat sublingual gland
-
Kawabata A, Morimoto N, Nishikawa H, Kuroda R, Oda Y, and Kakehi K (2000a) Activation of protease-activated receptor-2 (PAR-2) triggers mucin secretion in the rat sublingual gland. Biochem Biophys Res Commun 270:298-302.
-
(2000)
Biochem Biophys Res Commun
, vol.270
, pp. 298-302
-
-
Kawabata, A.1
Morimoto, N.2
Nishikawa, H.3
Kuroda, R.4
Oda, Y.5
Kakehi, K.6
-
21
-
-
4544250027
-
Receptor-activating peptides for PAR-1 and PAR-2 relax rat gastric artery via multiple mechanisms
-
Kawabata A, Nakaya Y, Ishiki T, Kubo S, Kuroda R, Sekiguchi F, Kawao N, Nishikawa H, and Kawai K (2004b) Receptor-activating peptides for PAR-1 and PAR-2 relax rat gastric artery via multiple mechanisms. Life Sci 75:2689-2702.
-
(2004)
Life Sci
, vol.75
, pp. 2689-2702
-
-
Kawabata, A.1
Nakaya, Y.2
Ishiki, T.3
Kubo, S.4
Kuroda, R.5
Sekiguchi, F.6
Kawao, N.7
Nishikawa, H.8
Kawai, K.9
-
22
-
-
0033997882
-
Proteinase-activated receptor-2 (PAR-2): Regulation of salivary and pancreatic exocrine secretion in vivo in rats and mice
-
Kawabata A, Nishikawa H, Kuroda R, Kawai K, and Hollenberg MD (2000b) Proteinase-activated receptor-2 (PAR-2): regulation of salivary and pancreatic exocrine secretion in vivo in rats and mice. Br J Pharmacol 129:1808-1814.
-
(2000)
Br J Pharmacol
, vol.129
, pp. 1808-1814
-
-
Kawabata, A.1
Nishikawa, H.2
Kuroda, R.3
Kawai, K.4
Hollenberg, M.D.5
-
23
-
-
0036166557
-
Effect of protease-activated receptor-2 deficiency on allergic dermatitis in the mouse ear
-
Kawagoe J, Takizawa T, Matsumoto J, Tamiya M, Meek SE, Smith AJ, Hunter GD, Plevin R, Saito N, Kanke T, et al. (2002) Effect of protease-activated receptor-2 deficiency on allergic dermatitis in the mouse ear. Jpn J Pharmacol 88:77-84.
-
(2002)
Jpn J Pharmacol
, vol.88
, pp. 77-84
-
-
Kawagoe, J.1
Takizawa, T.2
Matsumoto, J.3
Tamiya, M.4
Meek, S.E.5
Smith, A.J.6
Hunter, G.D.7
Plevin, R.8
Saito, N.9
Kanke, T.10
-
24
-
-
0030742507
-
Expression of trypsin in vascular endothelial cells
-
Koshikawa N, Nagashima Y, Miyagi Y, Mizushima H, Yanoma S, Yasumitsu H, and Miyazaki K (1997) Expression of trypsin in vascular endothelial cells. FEBS Lett 409:442-448.
-
(1997)
FEBS Lett
, vol.409
, pp. 442-448
-
-
Koshikawa, N.1
Nagashima, Y.2
Miyagi, Y.3
Mizushima, H.4
Yanoma, S.5
Yasumitsu, H.6
Miyazaki, K.7
-
25
-
-
0029943079
-
Agonist recognition by proteinase-activated receptor 2 and thrombin receptor. Importance of extracellular loop interactions for receptor function
-
Lerner DJ, Chen M, Tram T, and Coughlin SR (1996) Agonist recognition by proteinase-activated receptor 2 and thrombin receptor. Importance of extracellular loop interactions for receptor function. J Biol Chem 271:13943-13947.
-
(1996)
J Biol Chem
, vol.271
, pp. 13943-13947
-
-
Lerner, D.J.1
Chen, M.2
Tram, T.3
Coughlin, S.R.4
-
26
-
-
0035019636
-
Proteinaseactivated receptors
-
Macfarlane SR, Seatter MJ, Kanke T, Hunter GD, and Plevin R (2001) Proteinaseactivated receptors. Pharmacol Rev 53:245-282.
-
(2001)
Pharmacol Rev
, vol.53
, pp. 245-282
-
-
Macfarlane, S.R.1
Seatter, M.J.2
Kanke, T.3
Hunter, G.D.4
Plevin, R.5
-
27
-
-
0023733195
-
Tissue distribution of mRNAs encoding muscarinic acetylcholine receptor subtypes
-
Maeda A, Kubo T, Mishina M, and Numa S (1988) Tissue distribution of mRNAs encoding muscarinic acetylcholine receptor subtypes. FEBS Lett 239:339-342.
-
(1988)
FEBS Lett
, vol.239
, pp. 339-342
-
-
Maeda, A.1
Kubo, T.2
Mishina, M.3
Numa, S.4
-
28
-
-
0034662903
-
Multiple functional defects in peripheral autonomic organs in mice lacking muscarinic acetylcholine receptor gene for the M3 subtype
-
Matsui M, Motomura D, Karasawa H, Fujikawa T, Jiang J, Komiya Y, Takahashi S, and Taketo MM (2000) Multiple functional defects in peripheral autonomic organs in mice lacking muscarinic acetylcholine receptor gene for the M3 subtype. Proc Natl Acad Sci USA 97:9579-9584.
-
(2000)
Proc Natl Acad Sci USA
, vol.97
, pp. 9579-9584
-
-
Matsui, M.1
Motomura, D.2
Karasawa, H.3
Fujikawa, T.4
Jiang, J.5
Komiya, Y.6
Takahashi, S.7
Taketo, M.M.8
-
29
-
-
15444346942
-
Interactions of mast cell tryptase with thrombin receptors and PAR-2
-
Molino M, Barnathan ES, Numerof R, Clark J, Dreyer M, Cumashi A, Hoxie JA, Schechter N, Woolkalis M, and Brass LF (1997) Interactions of mast cell tryptase with thrombin receptors and PAR-2. J Biol Chem 272:4043-4049.
-
(1997)
J Biol Chem
, vol.272
, pp. 4043-4049
-
-
Molino, M.1
Barnathan, E.S.2
Numerof, R.3
Clark, J.4
Dreyer, M.5
Cumashi, A.6
Hoxie, J.A.7
Schechter, N.8
Woolkalis, M.9
Brass, L.F.10
-
30
-
-
0036896113
-
Signal transduction pathways involved in the mechanical responses to protease-activated receptors in rat colon
-
Mule F, Baffi MC, Falzone M, and Cerra MC (2002) Signal transduction pathways involved in the mechanical responses to protease-activated receptors in rat colon. J Pharmacol Exp Ther 303:1265-1272.
-
(2002)
J Pharmacol Exp Ther
, vol.303
, pp. 1265-1272
-
-
Mule, F.1
Baffi, M.C.2
Falzone, M.3
Cerra, M.C.4
-
31
-
-
0034762759
-
Novel fragments of the Sjogren's syndrome autoantigens alpha-fodrin and type 3 muscarinic acetylcholine receptor generated during cytotoxic lymphocyte granule-induced cell death
-
Nagaraju K, Cox A, Casciola-Rosen L, and Rosen A (2001) Novel fragments of the Sjogren's syndrome autoantigens alpha-fodrin and type 3 muscarinic acetylcholine receptor generated during cytotoxic lymphocyte granule-induced cell death. Arthritis Rheum 44:2376-2386.
-
(2001)
Arthritis Rheum
, vol.44
, pp. 2376-2386
-
-
Nagaraju, K.1
Cox, A.2
Casciola-Rosen, L.3
Rosen, A.4
-
32
-
-
4344605231
-
M3 muscarinic acetylcholine receptor plays a critical role in parasympathetic control of salivation in mice
-
Nakamura T, Matsui M, Uchida K, Futatsugi A, Kusakawa S, Matsumoto N, Nakamura K, Manabe T, Taketo MM, and Mikoshiba K (2004) M3 muscarinic acetylcholine receptor plays a critical role in parasympathetic control of salivation in mice. J Physiol (Lond) 558:561-575.
-
(2004)
J Physiol (Lond)
, vol.558
, pp. 561-575
-
-
Nakamura, T.1
Matsui, M.2
Uchida, K.3
Futatsugi, A.4
Kusakawa, S.5
Matsumoto, N.6
Nakamura, K.7
Manabe, T.8
Taketo, M.M.9
Mikoshiba, K.10
-
34
-
-
0043169397
-
Postsynaptic M1 and M3 receptors are responsible for the muscarinic enhancement of retrograde endocannabinoid signalling in the hippocampus
-
Ohno-Shosaku T, Matsui M, Fukudome Y, Shosaku J, Tsubokawa H, Taketo MM, Manabe T, and Kano M (2003) Postsynaptic M1 and M3 receptors are responsible for the muscarinic enhancement of retrograde endocannabinoid signalling in the hippocampus. Eur J Neurosci 18:109-116.
-
(2003)
Eur J Neurosci
, vol.18
, pp. 109-116
-
-
Ohno-Shosaku, T.1
Matsui, M.2
Fukudome, Y.3
Shosaku, J.4
Tsubokawa, H.5
Taketo, M.M.6
Manabe, T.7
Kano, M.8
-
36
-
-
0035968215
-
Neurosteroid hydroxylase CYP7B: Vivid reporter activity in dentate gyrus of gene-targeted mice and abolition of a widespread pathway of steroid and oxysterol hydroxylation
-
Rose K, Allan A, Gauldie S, Stapleton G, Dobbie L, Dott K, Martin C, Wang L, Hedlund E, Seckl JR, et al. (2001) Neurosteroid hydroxylase CYP7B: vivid reporter activity in dentate gyrus of gene-targeted mice and abolition of a widespread pathway of steroid and oxysterol hydroxylation. J Biol Chem 276:23937-23944.
-
(2001)
J Biol Chem
, vol.276
, pp. 23937-23944
-
-
Rose, K.1
Allan, A.2
Gauldie, S.3
Stapleton, G.4
Dobbie, L.5
Dott, K.6
Martin, C.7
Wang, L.8
Hedlund, E.9
Seckl, J.R.10
-
37
-
-
0026596254
-
Role of adrenergic and cholinergic mediators in salivary phospholipids secretion
-
Slomiany BL, Sengupta S, Piotrowski E, Lopez RA, and Slomiany A (1992) Role of adrenergic and cholinergic mediators in salivary phospholipids secretion. Biochim Biophys Acta 1124:171-177.
-
(1992)
Biochim Biophys Acta
, vol.1124
, pp. 171-177
-
-
Slomiany, B.L.1
Sengupta, S.2
Piotrowski, E.3
Lopez, R.A.4
Slomiany, A.5
-
38
-
-
0022317478
-
Regulation of functional mRNA levels for trypsin-like esteroproteases by 5 alpha-dihydrotestosterone and triiodothyronine in mouse submandibular salivary gland
-
Takuma T, Ichida T, and Kumegawa M (1985) Regulation of functional mRNA levels for trypsin-like esteroproteases by 5 alpha-dihydrotestosterone and triiodothyronine in mouse submandibular salivary gland. Arch Oral Biol 30:727-730.
-
(1985)
Arch Oral Biol
, vol.30
, pp. 727-730
-
-
Takuma, T.1
Ichida, T.2
Kumegawa, M.3
-
39
-
-
0019413175
-
Postnatal development of trypsin-like esteroproteases in mouse submandibular gland
-
Takuma T and Kumegawa M (1981) Postnatal development of trypsin-like esteroproteases in mouse submandibular gland. Histochemistry 72:25-31.
-
(1981)
Histochemistry
, vol.72
, pp. 25-31
-
-
Takuma, T.1
Kumegawa, M.2
-
40
-
-
0028878044
-
Oral pilocarpine: A review of its pharmacological properties and clinical potential in xerostomia
-
Wiseman LR and Faulds D (1995) Oral pilocarpine: a review of its pharmacological properties and clinical potential in xerostomia. Drugs 49:143-155.
-
(1995)
Drugs
, vol.49
, pp. 143-155
-
-
Wiseman, L.R.1
Faulds, D.2
|