메뉴 건너뛰기




Volumn 54, Issue 4, 2006, Pages 1165-1173

Antimuscarinic antibodies in primary Sjögren's syndrome reversibly inhibit the mechanism of fluid secretion by human submandibular salivary acinar cells

Author keywords

[No Author keywords available]

Indexed keywords

AUTOANTIBODY; CALCIUM ION; CHOLINERGIC RECEPTOR ANTIBODY; IMMUNOGLOBULIN G; MUSCARINIC M3 RECEPTOR; MUSCARINIC M3 RECEPTOR ANTIBODY; MUSCARINIC RECEPTOR ANTIBODY; UNCLASSIFIED DRUG;

EID: 33646343709     PISSN: 00043591     EISSN: None     Source Type: Journal    
DOI: 10.1002/art.21764     Document Type: Article
Times cited : (137)

References (44)
  • 1
    • 4344605231 scopus 로고    scopus 로고
    • M3 muscarinic acetylcholine receptor plays a critical role in parasympathetic control of salivation in mice
    • Nakamura T, Matsui M, Uchida K, Futatsugi A, Kusakawa S, Matsumoto N, et al. M3 muscarinic acetylcholine receptor plays a critical role in parasympathetic control of salivation in mice. J Physiol 2004;558:561-75.
    • (2004) J Physiol , vol.558 , pp. 561-575
    • Nakamura, T.1    Matsui, M.2    Uchida, K.3    Futatsugi, A.4    Kusakawa, S.5    Matsumoto, N.6
  • 2
    • 0034662903 scopus 로고    scopus 로고
    • Multiple functional defects in peripheral autonomic organs in mice lacking muscarinic acetylcholine receptor gene for the M3 subtype
    • Matsui M, Motomura D, Karasawa H, Fujikawa T, Jiang J, Komiya Y, et al. Multiple functional defects in peripheral autonomic organs in mice lacking muscarinic acetylcholine receptor gene for the M3 subtype. Proc Natl Acad Sci U S A 2000;97:9579-84.
    • (2000) Proc Natl Acad Sci U S A , vol.97 , pp. 9579-9584
    • Matsui, M.1    Motomura, D.2    Karasawa, H.3    Fujikawa, T.4    Jiang, J.5    Komiya, Y.6
  • 3
    • 0002236717 scopus 로고    scopus 로고
    • Mechanisms of secretion by salivary glands
    • Edgar WM, O'Mullane D, editors. London: BDJ
    • Smith PM. Mechanisms of secretion by salivary glands. In: Edgar WM, O'Mullane D, editors. Saliva and oral health. London: BDJ; 1996. p. 9-25.
    • (1996) Saliva and Oral Health , pp. 9-25
    • Smith, P.M.1
  • 4
    • 10444274947 scopus 로고    scopus 로고
    • Putative anti-muscarinic antibodies cannot be detected in patients with primary Sjogren's syndrome using conventional immunological approaches
    • Dawson LJ, Allison HE, Stanbury J, Fitzgerald D, Smith PM. Putative anti-muscarinic antibodies cannot be detected in patients with primary Sjogren's syndrome using conventional immunological approaches. Rheumatology (Oxford) 2004;43:1488-95.
    • (2004) Rheumatology (Oxford) , vol.43 , pp. 1488-1495
    • Dawson, L.J.1    Allison, H.E.2    Stanbury, J.3    Fitzgerald, D.4    Smith, P.M.5
  • 5
    • 0030028494 scopus 로고    scopus 로고
    • Circulating antibodies against rat parotid gland M3 muscarinic receptors in primary Sjogren's syndrome
    • Bacman S, Sterin-Borda L, Camusso JJ, Arana R, Hubscher O, Borda E. Circulating antibodies against rat parotid gland M3 muscarinic receptors in primary Sjogren's syndrome. Clin Exp Immunol 1996;104:454-9.
    • (1996) Clin Exp Immunol , vol.104 , pp. 454-459
    • Bacman, S.1    Sterin-Borda, L.2    Camusso, J.J.3    Arana, R.4    Hubscher, O.5    Borda, E.6
  • 6
    • 0036173407 scopus 로고    scopus 로고
    • Up-regulation of M3-muscarinic receptors in labial salivary gland acini in primary Sjogren's syndrome
    • Beroukas D, Goodfellow R, Hiscock J, Jonsson R, Gordon TP, Waterman SA. Up-regulation of M3-muscarinic receptors in labial salivary gland acini in primary Sjogren's syndrome. Lab Invest 2002;82:203-10.
    • (2002) Lab Invest , vol.82 , pp. 203-210
    • Beroukas, D.1    Goodfellow, R.2    Hiscock, J.3    Jonsson, R.4    Gordon, T.P.5    Waterman, S.A.6
  • 7
    • 8344255696 scopus 로고    scopus 로고
    • Inhibitory effects of autoantibodies on the muscarinic receptors in Sjogren's syndrome
    • Li J, Ha YM, Ku NY, Choi SY, Lee SJ, Oh SB, et al. Inhibitory effects of autoantibodies on the muscarinic receptors in Sjogren's syndrome. Lab Invest 2004;84:1430-8.
    • (2004) Lab Invest , vol.84 , pp. 1430-1438
    • Li, J.1    Ha, Y.M.2    Ku, N.Y.3    Choi, S.Y.4    Lee, S.J.5    Oh, S.B.6
  • 8
    • 0032560571 scopus 로고    scopus 로고
    • Transfer of human serum IgG to nonobese diabetic Igμ null mice reveals a role for autoantibodies in the loss of secretory function of exocrine tissues in Sjogren's syndrome
    • Robinson CP, Brayer J, Yamachika S, Esch TR, Peck AB, Stewart CA, et al. Transfer of human serum IgG to nonobese diabetic Igμ null mice reveals a role for autoantibodies in the loss of secretory function of exocrine tissues in Sjogren's syndrome. Proc Natl Acad Sci U S A 1998;95:7538-43.
    • (1998) Proc Natl Acad Sci U S A , vol.95 , pp. 7538-7543
    • Robinson, C.P.1    Brayer, J.2    Yamachika, S.3    Esch, T.R.4    Peck, A.B.5    Stewart, C.A.6
  • 9
    • 0033948273 scopus 로고    scopus 로고
    • Inhibitory effects of muscarinic receptor autoantibodies on parasympathetic neurotransmission in Sjögren's syndrome
    • Waterman SA, Gordon TP, Rischmueller M. Inhibitory effects of muscarinic receptor autoantibodies on parasympathetic neurotransmission in Sjögren's syndrome. Arthritis Rheum 2000;43:1647-54.
    • (2000) Arthritis Rheum , vol.43 , pp. 1647-1654
    • Waterman, S.A.1    Gordon, T.P.2    Rischmueller, M.3
  • 10
    • 8444247111 scopus 로고    scopus 로고
    • Passive transfer of Sjögren's syndrome IgG produces the pathophysiology of overactive bladder
    • Wang F, Jackson MW, Maughan V, Cavill D, Smith AJ, Waterman SA, et al. Passive transfer of Sjögren's syndrome IgG produces the pathophysiology of overactive bladder. Arthritis Rheum 2004;50:3637-45.
    • (2004) Arthritis Rheum , vol.50 , pp. 3637-3645
    • Wang, F.1    Jackson, M.W.2    Maughan, V.3    Cavill, D.4    Smith, A.J.5    Waterman, S.A.6
  • 11
    • 0346220029 scopus 로고    scopus 로고
    • Antiidiotypic antibodies neutralize autoantibodies that inhibit cholinergic neurotransmission
    • Cavill D, Waterman SA, Gordon TP. Antiidiotypic antibodies neutralize autoantibodies that inhibit cholinergic neurotransmission. Arthritis Rheum 2003;48:3597-602.
    • (2003) Arthritis Rheum , vol.48 , pp. 3597-3602
    • Cavill, D.1    Waterman, S.A.2    Gordon, T.P.3
  • 13
    • 0034025087 scopus 로고    scopus 로고
    • Impaired microvascular response to cholinergic stimuli in primary Sjogren's syndrome
    • Kovacs L, Torok T, Bari F, Keri Z, Kovacs A, Makula E, et al. Impaired microvascular response to cholinergic stimuli in primary Sjogren's syndrome. Ann Rheum Dis 2000;59:48-53.
    • (2000) Ann Rheum Dis , vol.59 , pp. 48-53
    • Kovacs, L.1    Torok, T.2    Bari, F.3    Keri, Z.4    Kovacs, A.5    Makula, E.6
  • 14
    • 26844506257 scopus 로고    scopus 로고
    • Antimuscarinic antibodies in Sjögren's syndrome: Where are we, and where are we going?
    • Dawson L, Tobin A, Smith P, Gordon T. Antimuscarinic antibodies in Sjögren's syndrome: where are we, and where are we going? [review]. Arthritis Rheum 2005;52:2984-95.
    • (2005) Arthritis Rheum , vol.52 , pp. 2984-2995
    • Dawson, L.1    Tobin, A.2    Smith, P.3    Gordon, T.4
  • 15
    • 0033708288 scopus 로고    scopus 로고
    • An investigation of interactions between the immune system and stimulus-secretion coupling in mouse submandibular acinar cells: A possible mechanism to account for reduced salivary flow rates associated with the onset of Sjogren's syndrome
    • Dawson LJ, Christmas SE, Smith PM. An investigation of interactions between the immune system and stimulus-secretion coupling in mouse submandibular acinar cells: a possible mechanism to account for reduced salivary flow rates associated with the onset of Sjogren's syndrome. Rheumatology (Oxford) 2000;39:1226-33.
    • (2000) Rheumatology (Oxford) , vol.39 , pp. 1226-1233
    • Dawson, L.J.1    Christmas, S.E.2    Smith, P.M.3
  • 16
    • 18744386132 scopus 로고    scopus 로고
    • Hydroxychloroquine therapy in patients with primary Sjogren's syndrome may improve salivary gland hypofunction by inhibition of glandular cholinesterase
    • Dawson LJ, Caulfield VL, Stanbury JB, Field AE, Christmas SE, Smith PM. Hydroxychloroquine therapy in patients with primary Sjogren's syndrome may improve salivary gland hypofunction by inhibition of glandular cholinesterase. Rheumatology (Oxford) 2005;44:449-55.
    • (2005) Rheumatology (Oxford) , vol.44 , pp. 449-455
    • Dawson, L.J.1    Caulfield, V.L.2    Stanbury, J.B.3    Field, A.E.4    Christmas, S.E.5    Smith, P.M.6
  • 17
    • 0035068208 scopus 로고    scopus 로고
    • Impaired neurotransmitter release from lacrimal and salivary gland nerves of a murine model of Sjogren's syndrome
    • Zoukhri D, Kublin CL. Impaired neurotransmitter release from lacrimal and salivary gland nerves of a murine model of Sjogren's syndrome. Invest Ophthalmol Vis Sci 2001;42:925-32.
    • (2001) Invest Ophthalmol Vis Sci , vol.42 , pp. 925-932
    • Zoukhri, D.1    Kublin, C.L.2
  • 18
    • 0035990370 scopus 로고    scopus 로고
    • Failure to detect antibodies to extracellular loop peptides of the muscarinic M3 receptor in primary Sjogren's syndrome
    • Cavill D, Waterman SA, Gordon TP. Failure to detect antibodies to extracellular loop peptides of the muscarinic M3 receptor in primary Sjogren's syndrome. J Rheumatol 2002;29:1342-4.
    • (2002) J Rheumatol , vol.29 , pp. 1342-1344
    • Cavill, D.1    Waterman, S.A.2    Gordon, T.P.3
  • 19
    • 0037215183 scopus 로고    scopus 로고
    • Classification criteria for Sjogren's syndrome
    • Vitali C. Classification criteria for Sjogren's syndrome. Ann Rheum Dis 2003;62:94-5.
    • (2003) Ann Rheum Dis , vol.62 , pp. 94-95
    • Vitali, C.1
  • 20
    • 0036092482 scopus 로고    scopus 로고
    • Classification criteria for Sjogren's syndrome: A revised version of the European criteria proposed by the American-European Consensus Group
    • Vitali C, Bombardieri S, Jonsson R, Moutsopoulos HM, Alexander EL, Carsons SE, et al, and the European Study Group on Classification Criteria for Sjogren's Syndrome. Classification criteria for Sjogren's syndrome: a revised version of the European criteria proposed by the American-European Consensus Group. Ann Rheum Dis 2002;61:554-8.
    • (2002) Ann Rheum Dis , vol.61 , pp. 554-558
    • Vitali, C.1    Bombardieri, S.2    Jonsson, R.3    Moutsopoulos, H.M.4    Alexander, E.L.5    Carsons, S.E.6
  • 21
    • 0022186670 scopus 로고
    • Measurement of protein using bicinchoninic acid (published erratum appears in Anal Biochem 1987;163:279)
    • Smith PK, Krohn RI, Hermanson GT, Mallia AK, Gartner FH, Provenzano MD, et al. Measurement of protein using bicinchoninic acid (published erratum appears in Anal Biochem 1987;163:279). Anal Biochem 1985;150:76-85.
    • (1985) Anal Biochem , vol.150 , pp. 76-85
    • Smith, P.K.1    Krohn, R.I.2    Hermanson, G.T.3    Mallia, A.K.4    Gartner, F.H.5    Provenzano, M.D.6
  • 22
    • 1842505257 scopus 로고    scopus 로고
    • Antibodies raised against the second extracellular loop of the human muscarinic M3 receptor mimic functional autoantibodies in Sjogren's syndrome
    • Cavill D, Waterman SA, Gordon TP. Antibodies raised against the second extracellular loop of the human muscarinic M3 receptor mimic functional autoantibodies in Sjogren's syndrome. Scand J Immunol 2004;59:261-6.
    • (2004) Scand J Immunol , vol.59 , pp. 261-266
    • Cavill, D.1    Waterman, S.A.2    Gordon, T.P.3
  • 23
    • 0026516974 scopus 로고
    • Acetylcholine- and caffeine-evoked repetitive transient Ca2+-activated K+ and Cl- currents in mouse submandibular cells
    • Smith PM, Gallacher DV. Acetylcholine- and caffeine-evoked repetitive transient Ca2+-activated K+ and Cl- currents in mouse submandibular cells. J Physiol 1992;449:109-20.
    • (1992) J Physiol , vol.449 , pp. 109-120
    • Smith, P.M.1    Gallacher, D.V.2
  • 24
    • 0026040522 scopus 로고
    • Influence of culture conditions on the androgen control of secretory component production by acinar cells from the rat lacrimal gland
    • Hann LE, Kelleher RS, Sullivan DA. Influence of culture conditions on the androgen control of secretory component production by acinar cells from the rat lacrimal gland. Invest Ophthalmol Vis Sci 1991;32:2610-21.
    • (1991) Invest Ophthalmol Vis Sci , vol.32 , pp. 2610-2621
    • Hann, L.E.1    Kelleher, R.S.2    Sullivan, D.A.3
  • 25
    • 0026587435 scopus 로고
    • Patch-clamp whole-cell pulse protocol measurements using a microcomputer
    • Smith PM. Patch-clamp whole-cell pulse protocol measurements using a microcomputer. J Physiol 1992;446:72P.
    • (1992) J Physiol , vol.446
    • Smith, P.M.1
  • 26
    • 10844251575 scopus 로고    scopus 로고
    • Local and global calcium signals and fluid and electrolyte secretion in mouse submandibular acinar cells
    • Harmer AR, Smith PM, Gallacher DV. Local and global calcium signals and fluid and electrolyte secretion in mouse submandibular acinar cells. Am J Physiol Gastrointest Liver Physiol 2005;288: G118-24.
    • (2005) Am J Physiol Gastrointest Liver Physiol , vol.288
    • Harmer, A.R.1    Smith, P.M.2    Gallacher, D.V.3
  • 27
    • 0027332202 scopus 로고
    • Ca2+ oscillations in pancreatic acinar cells: Spatiotemporal relationships and functional implications
    • Thorn P, Lawrie AM, Smith PM, Gallacher DV, Petersen OH. Ca2+ oscillations in pancreatic acinar cells: spatiotemporal relationships and functional implications. Cell Calcium 1993;14:746-57.
    • (1993) Cell Calcium , vol.14 , pp. 746-757
    • Thorn, P.1    Lawrie, A.M.2    Smith, P.M.3    Gallacher, D.V.4    Petersen, O.H.5
  • 28
    • 0035145180 scopus 로고    scopus 로고
    • Muscarinic acetylcholine receptor antibodies as a new marker of dry eye Sjogren syndrome
    • Bacman S, Berra A, Sterin-Borda L, Borda E. Muscarinic acetylcholine receptor antibodies as a new marker of dry eye Sjogren syndrome. Invest Ophthalmol Vis Sci 2001;42:321-7.
    • (2001) Invest Ophthalmol Vis Sci , vol.42 , pp. 321-327
    • Bacman, S.1    Berra, A.2    Sterin-Borda, L.3    Borda, E.4
  • 29
    • 0031975963 scopus 로고    scopus 로고
    • Autoantibodies against lacrimal gland M3 muscarinic acetylcholine receptors in patients with primary Sjogren's syndrome
    • Bacman S, Perez Leiros C, Sterin-Borda L, Hubscher O, Arana R, Borda E. Autoantibodies against lacrimal gland M3 muscarinic acetylcholine receptors in patients with primary Sjogren's syndrome. Invest Ophthalmol Vis Sci 1998;39:151-6.
    • (1998) Invest Ophthalmol Vis Sci , vol.39 , pp. 151-156
    • Bacman, S.1    Perez Leiros, C.2    Sterin-Borda, L.3    Hubscher, O.4    Arana, R.5    Borda, E.6
  • 30
    • 0031593751 scopus 로고    scopus 로고
    • Human primary Sjogren's syndrome autoantibodies as mediators of nitric oxide release coupled to lacrimal gland muscarinic acetylcholine receptors
    • Bacman SR, Berra A, Sterin-Borda L, Borda ES. Human primary Sjogren's syndrome autoantibodies as mediators of nitric oxide release coupled to lacrimal gland muscarinic acetylcholine receptors. Curr Eye Res 1998;17:1135-42.
    • (1998) Curr Eye Res , vol.17 , pp. 1135-1142
    • Bacman, S.R.1    Berra, A.2    Sterin-Borda, L.3    Borda, E.S.4
  • 31
    • 0035712662 scopus 로고    scopus 로고
    • Autoantibodies in primary Sjogren's syndrome: New insights into mechanisms of autoantibody diversification and disease pathogenesis
    • Gordon TP, Bolstad AI, Rischmueller M, Jonsson R, Waterman SA. Autoantibodies in primary Sjogren's syndrome: new insights into mechanisms of autoantibody diversification and disease pathogenesis. Autoimmunity 2001;34:123-32.
    • (2001) Autoimmunity , vol.34 , pp. 123-132
    • Gordon, T.P.1    Bolstad, A.I.2    Rischmueller, M.3    Jonsson, R.4    Waterman, S.A.5
  • 32
    • 24944481740 scopus 로고    scopus 로고
    • Clinical associations of autoantibodies to human muscarinic acetylcholine receptor 3(21.3-228) in primary Sjogren's syndrome
    • Kovacs L, Marczinovits I, Gyorgy A, Toth GK, Dorgai L, Pal J, et al. Clinical associations of autoantibodies to human muscarinic acetylcholine receptor 3(21.3-228) in primary Sjogren's syndrome. Rheumatology (Oxford) 2005;44:1021-5.
    • (2005) Rheumatology (Oxford) , vol.44 , pp. 1021-1025
    • Kovacs, L.1    Marczinovits, I.2    Gyorgy, A.3    Toth, G.K.4    Dorgai, L.5    Pal, J.6
  • 33
    • 0032926895 scopus 로고    scopus 로고
    • Activation of nitric oxide signaling through muscarinic receptors in submandibular glands by primary Sjogren syndrome antibodies
    • Perez Leiros C, Sterin-Borda L, Hubscher O, Arana R, Borda ES. Activation of nitric oxide signaling through muscarinic receptors in submandibular glands by primary Sjogren syndrome antibodies. Clin Immunol 1999;90:190-5.
    • (1999) Clin Immunol , vol.90 , pp. 190-195
    • Perez Leiros, C.1    Sterin-Borda, L.2    Hubscher, O.3    Arana, R.4    Borda, E.S.5
  • 34
    • 0033785033 scopus 로고    scopus 로고
    • Evidence for antimuscarinic acetylcholine receptor antibody-mediated secretory dysfunction in NOD mice
    • Nguyen KH, Brayer J, Cha S, Diggs S, Yasunari U, Hilal G, et al. Evidence for antimuscarinic acetylcholine receptor antibody-mediated secretory dysfunction in NOD mice. Arthritis Rheum 2000;43:2297-306.
    • (2000) Arthritis Rheum , vol.43 , pp. 2297-2306
    • Nguyen, K.H.1    Brayer, J.2    Cha, S.3    Diggs, S.4    Yasunari, U.5    Hilal, G.6
  • 35
    • 4043140159 scopus 로고    scopus 로고
    • Detection of anti-type 3 muscarinic acetylcholine receptor autoantibodies in the sera of Sjogren's syndrome patients by use of a transfected cell line assay
    • Gao J, Cha S, Jonsson R, Opalko J, Peck AB. Detection of anti-type 3 muscarinic acetylcholine receptor autoantibodies in the sera of Sjogren's syndrome patients by use of a transfected cell line assay. Arthritis Rheum 2004;50:2615-21.
    • (2004) Arthritis Rheum , vol.50 , pp. 2615-2621
    • Gao, J.1    Cha, S.2    Jonsson, R.3    Opalko, J.4    Peck, A.B.5
  • 36
    • 0026594290 scopus 로고
    • Ins(1,3,4,5)P4 promotes sustained activation of the Ca2+-dependent Cl- current in isolated mouse lacrimal cells
    • Smith PM. Ins(1,3,4,5)P4 promotes sustained activation of the Ca2+-dependent Cl- current in isolated mouse lacrimal cells. Biochem J 1992;283:27-30.
    • (1992) Biochem J , vol.283 , pp. 27-30
    • Smith, P.M.1
  • 37
    • 0035253076 scopus 로고    scopus 로고
    • Role of Ins(1,4,5)P3, cADP-ribose and nicotinic acid-adenine dinucleotide phosphate in Ca2+ signalling in mouse submandibular acinar cells
    • Harmer AR, Gallacher DV, Smith PM. Role of Ins(1,4,5)P3, cADP-ribose and nicotinic acid-adenine dinucleotide phosphate in Ca2+ signalling in mouse submandibular acinar cells. Biochem J 2001;353:555-60.
    • (2001) Biochem J , vol.353 , pp. 555-560
    • Harmer, A.R.1    Gallacher, D.V.2    Smith, P.M.3
  • 38
    • 0022931417 scopus 로고
    • Sjogren's syndrome: Clinical and laboratory features, immunopathogenesis, and management
    • Scully C. Sjogren's syndrome: clinical and laboratory features, immunopathogenesis, and management. Oral Surg Oral Med Oral Pathol 1986;62:510-23.
    • (1986) Oral Surg Oral Med Oral Pathol , vol.62 , pp. 510-523
    • Scully, C.1
  • 39
    • 0029819151 scopus 로고    scopus 로고
    • Current concepts of autoimmune exocrinopathy: Immunologic mechanisms in the salivary pathology of Sjogren's syndrome
    • Fox PC, Speight PM. Current concepts of autoimmune exocrinopathy: immunologic mechanisms in the salivary pathology of Sjogren's syndrome. Crit Rev Oral Biol Med 1996;7:144-58.
    • (1996) Crit Rev Oral Biol Med , vol.7 , pp. 144-158
    • Fox, P.C.1    Speight, P.M.2
  • 40
    • 85047687824 scopus 로고    scopus 로고
    • Autonomic "myasthenia": The case for an autoimmune pathogenesis
    • Drachman DB. Autonomic "myasthenia": the case for an autoimmune pathogenesis. J Clin Invest 2003;111:797-9.
    • (2003) J Clin Invest , vol.111 , pp. 797-799
    • Drachman, D.B.1
  • 41
    • 13944255755 scopus 로고    scopus 로고
    • A peptide of human muscarinic acetylcholine receptor 3 is antigenic in primary Sjogren's syndrome
    • Marczinovits I, Kovacs L, Gyorgy A, Toth GK, Dorgai L, Molnar J, et al. A peptide of human muscarinic acetylcholine receptor 3 is antigenic in primary Sjogren's syndrome. J Autoimmun 2005;24: 47-54.
    • (2005) J Autoimmun , vol.24 , pp. 47-54
    • Marczinovits, I.1    Kovacs, L.2    Gyorgy, A.3    Toth, G.K.4    Dorgai, L.5    Molnar, J.6
  • 42
    • 0036787341 scopus 로고    scopus 로고
    • Antibody-mediated gastrointestinal dysmotility in scleroderma
    • Goldblatt F, Gordon TP, Waterman SA. Antibody-mediated gastrointestinal dysmotility in scleroderma. Gastroenterology 2002;123:1144-50.
    • (2002) Gastroenterology , vol.123 , pp. 1144-1150
    • Goldblatt, F.1    Gordon, T.P.2    Waterman, S.A.3
  • 43
    • 0036798177 scopus 로고    scopus 로고
    • Correlations between the functional integrity of the endoplasmic reticulum and polarized Ca2+ signalling in mouse lacrimal acinar cells: A role for inositol 1,3,4,5-tetrakisphosphate
    • Harmer AR, Gallacher DV, Smith PM. Correlations between the functional integrity of the endoplasmic reticulum and polarized Ca2+ signalling in mouse lacrimal acinar cells: a role for inositol 1,3,4,5-tetrakisphosphate. Biochem J 2002;367:137-43.
    • (2002) Biochem J , vol.367 , pp. 137-143
    • Harmer, A.R.1    Gallacher, D.V.2    Smith, P.M.3
  • 44
    • 0034711691 scopus 로고    scopus 로고
    • Mechanism of block of nicotinic acetylcholine receptor channels by purified IgG from seropositive patients with myasthenia gravis
    • Jahn K, Franke C, Bufler J. Mechanism of block of nicotinic acetylcholine receptor channels by purified IgG from seropositive patients with myasthenia gravis. Neurology 2000;54:474-9.
    • (2000) Neurology , vol.54 , pp. 474-479
    • Jahn, K.1    Franke, C.2    Bufler, J.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.