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Volumn 9, Issue 1, 2007, Pages 157-160

Total synthesis of potential antitumor agent, (-)-dictyostatin

Author keywords

[No Author keywords available]

Indexed keywords

ANTINEOPLASTIC AGENT; DICTYOSTATIN; MACROLIDE; UNCLASSIFIED DRUG;

EID: 33846418752     PISSN: 15237060     EISSN: None     Source Type: Journal    
DOI: 10.1021/ol062737k     Document Type: Article
Times cited : (63)

References (42)
  • 1
    • 0001843250 scopus 로고
    • Taxane Anticancer Agents
    • Georg, G. I, Chen, T. T, Ojima, I, Vyas, D. M, Eds, American Chemical Society: Washington, D.C
    • Taxane Anticancer Agents; Georg, G. I., Chen, T. T., Ojima, I., Vyas, D. M., Eds.; ACS Symposium Series 583, American Chemical Society: Washington, D.C., 1995.
    • (1995) ACS Symposium Series , vol.583
  • 20
    • 33846457074 scopus 로고    scopus 로고
    • In comparison, Paterson's synthesis of 1 involved 27 steps for the longest linear sequence in 3.8% yield (ref 7a). Curran's 34 steps afforded 1% yield (ref 7b), and the 26-step longest sequence by Phillips yielded ∼1% (ref 8).
    • In comparison, Paterson's synthesis of 1 involved 27 steps for the longest linear sequence in 3.8% yield (ref 7a). Curran's 34 steps afforded 1% yield (ref 7b), and the 26-step longest sequence by Phillips yielded ∼1% (ref 8).
  • 24
    • 0001383044 scopus 로고    scopus 로고
    • 1H NMR of the crude samples for all of the crotylboration reactions during our synthesis. For crotylboration of chiral aldehydes, see: Brown, H. C.; Bhat, K. S.; Randad, R. S. J. Org. Chem. 1987, 52, 3701.
    • 1H NMR of the crude samples for all of the crotylboration reactions during our synthesis. For crotylboration of chiral aldehydes, see: Brown, H. C.; Bhat, K. S.; Randad, R. S. J. Org. Chem. 1987, 52, 3701.
  • 32
    • 28044453908 scopus 로고    scopus 로고
    • 4Pd. For an update on Negishi coupling, see: Negishi, E.; Hu, Q.; Huang, Z.; Qian, M.; Wang, G. Aldrichimica Acta 2005, 38, 71.
    • 4Pd. For an update on Negishi coupling, see: Negishi, E.; Hu, Q.; Huang, Z.; Qian, M.; Wang, G. Aldrichimica Acta 2005, 38, 71.
  • 33
    • 21144447289 scopus 로고    scopus 로고
    • For a review on recent advances in the chemistry of lithium aminoborohydrides, see
    • For a review on recent advances in the chemistry of lithium aminoborohydrides, see: Pasumansky, L.; Singaram, B.; Goralski, C. T. Aldrichimica Acta 2005, 38, 61.
    • (2005) Aldrichimica Acta , vol.38 , pp. 61
    • Pasumansky, L.1    Singaram, B.2    Goralski, C.T.3
  • 40
    • 33846462542 scopus 로고    scopus 로고
    • 13C NMR of our sample (1.5 mg) matched with those reported in the literature (refs 7 and 8).
    • 13C NMR of our sample (1.5 mg) matched with those reported in the literature (refs 7 and 8).
  • 41
    • 0037000811 scopus 로고    scopus 로고
    • For a review on pinane-based versatile allyl borane reagents, see
    • For a review on pinane-based versatile "allyl" borane reagents, see: Ramachandran, P. V. Aldrichimica Acta 2002, 35, 23.
    • (2002) Aldrichimica Acta , vol.35 , pp. 23
    • Ramachandran, P.V.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.