A combinatorial approach to substrate discrimination in the P450 CYP1A subfamily

Biochimica et Biophysica Acta - General Subjects

Volumn 1770, Issue 3, 2007, Pages 446-457

  Taly, Valérie ^a   Urban, Philippe ^a   Truan, Gilles ^a   Pompon, Denis ^a  

^a CNRS   (France)

Author keywords

CYP1A1; CYP1A2; DNA shuffling; Fluorescein; Multivariate statistic; Mutant; ProSAR; Random mutagenesis; Resorufin

Indexed keywords

7 ALKOXYRESORUFIN; CYTOCHROME P450; CYTOCHROME P450 1A; ENZYME VARIANT; ESTER DERIVATIVE; ETHOXYFLUORESCEIN ETHYL ESTER; RECOMBINANT PROTEIN; RESORUFIN DERIVATIVE; UNCLASSIFIED DRUG;

AMINO ACID SEQUENCE; ARTICLE; CLUSTER ANALYSIS; COMBINATORIAL CHEMISTRY; ENZYME ACTIVITY; ENZYME ASSAY; ENZYME SPECIFICITY; ENZYME SUBSTRATE; KINETICS; MULTIVARIATE ANALYSIS; MUTAGENESIS; PRIORITY JOURNAL; PROTEIN EXPRESSION; SEQUENCE ANALYSIS; STATISTICAL ANALYSIS; WILD TYPE; YEAST;

AMINO ACID SEQUENCE; ANIMALS; CYTOCHROME P-450 CYP1A1; GENE LIBRARY; HUMANS; MICE; MOLECULAR SEQUENCE DATA; MUTAGENESIS, SITE-DIRECTED; OXAZINES; RABBITS; SACCHAROMYCES CEREVISIAE; SEQUENCE HOMOLOGY, AMINO ACID; SUBSTRATE SPECIFICITY;

MAMMALIA;

EID: 33846370752     PISSN: 03044165     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bbagen.2006.08.005     Document Type: Article

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