In vitro and in vivo effect of BU99006 (5-isothiocyanato-2-benzofuranyl-2-imidazoline) on I2 binding in relation to MAO: Evidence for two distinct I2 binding sites

Neuropharmacology

Volumn 52, Issue 2, 2007, Pages 395-404

  Paterson, Louise M ^a   Tyacke, Robin J ^a   Robinson, Emma S J ^a   Nutt, David J ^a   Hudson, Alan L ^b  

^a UNIVERSITY OF BRISTOL   (United Kingdom)

^b UNIVERSITY OF ALBERTA   (Canada)

Author keywords

2BFI; Autoradiography; BU99006; I2; Imidazoline binding site; MAO; Monoamine oxidase

Indexed keywords

2 (2 BENZOFURANYL) 2 IMIDAZOLINE; 2 (2 IMIDAZOLIN 2 YL)QUINOLINE; 5 ISOTHIOCYANATO 2 BENZOFURANYL 2 IMIDAZOLINE; AMINE OXIDASE (FLAVIN CONTAINING); AMINE OXIDASE (FLAVIN CONTAINING) ISOENZYME A; AMINE OXIDASE (FLAVIN CONTAINING) ISOENZYME B; BENZOFURAN DERIVATIVE; BU 99006; CLORGYLINE; IMIDAZOLINE DERIVATIVE; ISOTHIOCYANIC ACID DERIVATIVE; LIGAND; RADIOLIGAND; SELEGILINE; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BINDING AFFINITY; CONTROLLED STUDY; DRUG BINDING SITE; DRUG EFFECT; DRUG MECHANISM; DRUG PROTEIN BINDING; ENZYME ACTIVITY; HALF LIFE TIME; IN VITRO STUDY; IN VIVO STUDY; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; RAT;

AFFINITY LABELS; ANALYSIS OF VARIANCE; ANIMALS; AUTORADIOGRAPHY; BENZOFURANS; BINDING, COMPETITIVE; BRAIN; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG INTERACTIONS; FEMALE; IMIDAZOLES; IMIDAZOLINES; MALE; MICE; MICE, INBRED CBA; MONOAMINE OXIDASE; RATS; RATS, WISTAR; REACTION TIME; SEROTONIN; TIME FACTORS; TRITIUM;

EID: 33846356373     PISSN: 00283908     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.neuropharm.2006.08.010     Document Type: Article

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