Investigation on the structure of the active site of monoamine oxidase-B by affinity labeling with the selective inhibitor lazabemide and by site-directed mutagenesis

European Journal of Biochemistry

Volumn 236, Issue 3, 1996, Pages 996-1002

  Cesura, Andrea M ^a,c   Gottowik, Jürgen ^a   Lahm, Hans Werner ^b   Lang, Gabrielle ^a   Imhof, René ^a   Malherbe, Pari ^a   Röthlisberger, Urs ^b   Da Prada, Mosé ^a  

^a Preclinical Research   (Switzerland)

^b F HOFFMANN LA ROCHE LTD   (Switzerland)

^c F HOFFMANN LA ROCHE LTD   (Switzerland)

Author keywords

affinity labeling; lazabemide; monoamine oxidase; protein structure; site directed mutagenesis

Indexed keywords

AMINE OXIDASE (FLAVIN CONTAINING) ISOENZYME B; LAZABEMIDE;

AFFINITY LABELING; ARTICLE; CONTROLLED STUDY; ENZYME ACTIVE SITE; ENZYME BINDING; ENZYME STRUCTURE; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HUMAN; HUMAN TISSUE; LIVER; PRIORITY JOURNAL; SITE DIRECTED MUTAGENESIS;

GYMNOMYZA SAMOENSIS;

EID: 0029923889     PISSN: 00142956     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1432-1033.1996.00996.x     Document Type: Article

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