Fragment based approach for the investigation of HIV-1 integrase inhibition

Letters in Drug Design and Discovery

Volumn 4, Issue 2, 2007, Pages 99-105

  Polanski, J ^a   Niedbala, H ^a   Musiol, R ^a   Podeszwa, B ^a   Tabak, D ^a   Palka, A ^a   Mencel, A ^a   Mouscadet, J F ^b   Le Bret, M ^b  

^a UNIVERSITY OF SILESIA   (Poland)

^b CNRS   (France)

Author keywords

HIV 1 integrase inhibition; Quinoline derivatives; Structure activity relationships

Indexed keywords

2 [2 (4 CHLOROPHENYL)VINYL] 5,7 DINITRO 8 NITROQUINOLINE; 2 [2 (4 METHOXYPHENYL)VINYL] 5,7 DINITRO 8 NITROQUINOLINE; 5 HYDROXY 2 METHYL 8 NITROQUINOLINE 6 CARBOXYLIC ACID 2 (4 HYDROXYPHENYL)ETHYLAMIDE; 5 HYDROXY 2 METHYL 8 NITROQUINOLINE 6 CARBOXYLIC ACID 4 METHYLBENZYLAMIDE; 5 HYDROXY 2 METHYLQUINOLINE 6 CARBOXYLIC ACID 2 (4 HYDROXYPHENYL)ETHYLAMIDE; 5 HYDROXY 2 METHYLQUINOLINE 6 CARBOXYLIC ACID 4 BROMOANILIDE; 5 HYDROXY 2 METHYLQUINOLINE 6 CARBOXYLIC ACID 4 FLUOROBENZYLAMIDE; 8 HYDROXY 2 METHYLQUINOLINE 7 CARBOXYLIC ACID 4 FLUOROBENZYLAMIDE; 8 HYDROXY 2 [2 (4 METHOXYPHENYL)VINYL] 5 NITROQUINOLINE 7 CARBOXYLIC ACID; 8 HYDROXY 7 QUINALDIC ACID; INTEGRASE; INTEGRASE INHIBITOR; MAGNESIUM; N (4 FLUOROBENZYL) 8 HYDROXY 5 (TETRAHYDRO 2H 1,2 THIAZIN 2 YL) 1,6 NAPHTHYRIDINE 7 CARBOXAMIDE S,S DIOXIDE; N,N DI (5 HYDROXY 2 METHYLQUINOLINE 6 CARBONYL)ETHANE 1,2 DIAMINE; N,N DI (8 HYDROXY 2 METHYLQUINOLINE 7 CARBONYL)ETHANE 1,2 DIAMINE; N,N DI (8 HYDROXY 2 METHYLQUINOLINE 7 CARBONYL)PIPERAZINE; N,N DI (8 HYDROXY 2 METHYLQUINOLINE 7 CARBONYL)PROPANE 1,3 DIAMINE; NAPHTHYRIDINE DERIVATIVE; QUINOLINE DERIVATIVE; STYRYLQUINOLINE DERIVATIVE; UNCLASSIFIED DRUG;

ARTICLE; COMPLEX FORMATION; DRUG CONFORMATION; DRUG DESIGN; DRUG INHIBITION; DRUG RESEARCH; DRUG SCREENING; DRUG STRUCTURE; ELECTRON; ENZYME INHIBITION; PRIORITY JOURNAL; STRUCTURE ACTIVITY RELATION; SUBSTITUTION REACTION;

EID: 33846303132     PISSN: 15701808     EISSN: None     Source Type: Journal    
DOI: 10.2174/157018007779422532     Document Type: Article

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