Role of hormone cofactors in the human papillomavirus-induced carcinogenesis of the uterine cervix

Molecular and Cellular Endocrinology

Volumn 264, Issue 1-2, 2007, Pages 1-5

  Delvenne, Philippe ^a   Herman, Ludivine ^a   Kholod, Natalia ^a   Caberg, Jean Hubert ^a   Herfs, Michaël ^a   Boniver, Jacques ^a   Jacobs, Nathalie ^a   Hubert, Pascale ^a  

^a Department of Pathology   (Belgium)

Author keywords

Carcinogenesis; Human papillomavirus; Metaplasia; Sexual hormones

Indexed keywords

SEX HORMONE; STEROID HORMONE;

CANCER RESEARCH; CARCINOGENESIS; CELL TRANSFORMATION; DNA BINDING; GENE EXPRESSION; HORMONE ACTION; HORMONE BINDING; HORMONE DETERMINATION; HORMONE RESPONSE; HUMAN; IMMUNE SYSTEM; MALIGNANT TRANSFORMATION; NONHUMAN; PAPILLOMA VIRUS; PRIORITY JOURNAL; PROTEIN FUNCTION; REVIEW; SQUAMOUS CELL METAPLASIA; UTERINE CERVIX CARCINOMA; VIRUS INFECTION;

CARCINOMA, SQUAMOUS CELL; CELL TRANSFORMATION, VIRAL; CERVIX UTERI; FEMALE; GENE EXPRESSION REGULATION, VIRAL; GONADAL STEROID HORMONES; HUMANS; METAPLASIA; TUMOR VIRUS INFECTIONS; UTERINE CERVICAL NEOPLASMS;

EID: 33846275311     PISSN: 03037207     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.mce.2006.10.014     Document Type: Review

References (66)

1. Al Saleh W., Giannini S.L., Jacobs N., Moutschen M., Doyen J., Boniver J., and Delvenne P. Correlation of T-helper secretory differentiation and types of antigen-presenting cells in squamous intraepithelial lesions of the uterine cervix. J. Pathol. 184 (1998) 283-290
2. Al-Saleh W., Delvenne P., Arrese J.E., Nikkels A.F., Pierard G.E., and Boniver J. Inverse modulation of intraepithelial Langerhans' cells and stromal macrophage/dendrocyte populations in human papillomavirus-associated squamous intraepithelial lesions of the cervix. Virchows Arch. 427 (1995) 41-48
3. Arbeit J.M., Howley P.M., and Hanahan D. Chronic estrogen-induced cervical and vaginal squamous carcinogenesis in human papillomavirus type 16 transgenic mice. Proc. Natl. Acad. Sci. U.S.A. 93 (1996) 2930-2935
4. Auborn K.J., Woodworth C., Dipaolo J.A., and Bradlow H.L. The interaction between HPV infection and estrogen metabolism in cervical carcinogenesis. Int. J. Cancer 49 (1991) 867-869
5. Blachon S., and Demeret C. The regulatory E2 proteins of human genital papillomaviruses are pro-apoptotic. Biochimie 85 (2003) 813-819
6. Blattner W.A. Human retroviruses: their role in cancer. Proc. Assoc. Am. Phys. 111 (1999) 563-572
7. Bosch F.X., Manos M.M., Munoz N., Sherman M., Jansen A.M., Peto J., Schiffman M.H., Moreno V., Kurman R., Shah K.V., Alihonou E., Bayo S., Mokhtar H.C., Chicareon S., Daudt A., Delosrios E., Ghadirian P., Kitinya J.N., Koulibaly M., Ngelangel C., Tintore L.M.P., Riosdalenz J.L., Sarjadi, Schneider A., Tafur L., Teyssie A.R., Rolon P.A., Torroella M., Tapia A.V., Wabinga H.R., Zatonski W., Sylla B., Vizcaino P., Magnin D., Kaldor J., Greer C., and Wheeler C. Prevalence of human papillomavirus in cervical-cancer: a worldwide perspective. J. Natl. Cancer Inst. 87 (1995) 796-802
8. Brady H., Doubleday M., Gayo-Fung L.M., Hickman M., Khammungkhune S., Kois A., Lipps S., Pierce S., Richard N., Shevlin G., Sutherland M.K., Anderson D.W., Bhagwat S.S., and Stein B. Differential response of estrogen receptors alpha and beta to SP500263, a novel potent selective estrogen receptor modulator. Mol. Pharmacol. 61 (2002) 562-568
9. Brake T., and Lambert P.F. Estrogen contributes to the onset, persistence, and malignant progression of cervical cancer in a human papillomavirus-transgenic mouse model. Proc. Natl. Acad. Sci. U.S.A. 102 (2005) 2490-2495
10. Brisson J., Morin C., Fortier M., Roy M., Bouchard C., Leclerc J., Christen A., Guimont C., Penault F., and Meisels A. Risk factors for cervical intraepithelial neoplasia: differences between low- and high-grade lesions. Am. J. Epidemiol. 140 (1994) 700-710
11. Buckley C. In: Stern P.L., and Stanley M.A. (Eds). The Pathology of Cervical Intra-Epithelial Neoplasia, Carcinoma and Human Papillomavirus Infection (Human Papillomavirus and Cervical Cancer Biology and Immunology) (1994), Oxford University Press, Oxford 1-27
12. Burghardt E., and Ostor A.G. Site and origin of squamous cervical cancer: a histomorphologic study. Obstet. Gynecol. 62 (1983) 117-127
13. Cho C.W., Poo H., Cho Y.S., Cho M.C., Lee K.A., Lee S.J., Park S.N., Kim I.K., Jung Y.K., Choe Y.K., Yeom Y.I., Choe I.S., and Yoon D.Y. HPV E6 antisense induces apoptosis in CaSki cells via suppression of E6 splicing. Exp. Mol. Med. 34 (2002) 159-166
14. de Vet H.C., and van Leeuwen F.E. Dietary guidelines for cancer prevention: the etiology of a confused debate. Nutr. Cancer 8 (1986) 223-229
15. Demeret C., Garcia-Carranca A., and Thierry F. Transcription-independent triggering of the extrinsic pathway of apoptosis by human papillomavirus 18 E2 protein. Oncogene 22 (2003) 168-175
16. Desaintes C., Demeret C., Goyat S., Yaniv M., and Thierry F. Expression of the papillomavirus E2 protein in HeLa cells leads to apoptosis. EMBO J. 16 (1997) 504-514
17. Elson D.A., Riley R.R., Lacey A., Thordarson G., Talamantes F.J., and Arbeit J.M. Sensitivity of the cervical transformation zone to estrogen-induced squamous carcinogenesis. Cancer Res. 60 (2000) 1267-1275
18. Fujishita A., Nakane P.K., Koji T., Masuzaki H., Chavez R.O., Yamabe T., and Ishimaru T. Expression of estrogen and progesterone receptors in endometrium and peritoneal endometriosis: an immunohistochemical and in situ hybridization study. Fertil. Steril. 67 (1997) 856-864
19. Giannini S.L., Al Saleh W., Piron H., Jacobs N., Doyen J., Boniver J., and Delvenne P. Cytokine expression in squamous intraepithelial lesions of the uterine cervix: implications for the generation of local immunosuppression. Clin. Exp. Immunol. 113 (1998) 183-189
20. Giannini S.L., Hubert P., Doyen J., Boniver J., and Delvenne P. Influence of the mucosal epithelium microenvironment on Langerhans cells: implications for the development of squamous intraepithelial lesions of the cervix. Int. J. Cancer 97 (2002) 654-659
21. Gilmore W., Weiner L.P., and Correale J. Effect of estradiol on cytokine secretion by proteolipid protein-specific T cell clones isolated from multiple sclerosis patients and normal control subjects. J. Immunol. 158 (1997) 446-451
22. Griffiths C.E., Dearman R.J., Cumberbatch M., and Kimber I. Cytokines and Langerhans cell mobilisation in mouse and man. Cytokine 32 (2005) 67-70
23. Hendrickson M.R., and Kempson R.L. In: Sternberg S.S. (Ed). Normal Histology of the Uterus and Fallopian Tubes (Histology for Pathologists) (1997), Lippincott-Raven, Philadelphia 879-923
24. Hubert P., Giannini S.L., Vanderplasschen A., Franzen-Detrooz E., Jacobs N., Boniver J., and Delvenne P. Dendritic cells induce the death of human papillomavirus transformed keratinocytes. FASEB J. 15 (2001) U187-U210
25. Hubert P., van den Brule F., Giannini S.L., Franzen-Detrooz E., Boniver J., and Delvenne P. Colonization of in vitro-formed cervical human papillomavirus-associated (pre)neoplastic lesions with dendritic cells-role of granulocyte/macrophage colony-stimulating factor. Am. J. Pathol. 154 (1999) 775-784
26. Kanda N., and Watanabe S. 17beta-estradiol stimulates the growth of human keratinocytes by inducing cyclin D2 expression. J. Invest. Dermatol. 123 (2004) 319-328
27. Kanda N., and Watanabe S. 17beta-estradiol inhibits oxidative stress-induced apoptosis in keratinocytes by promoting Bcl-2 expression. J. Invest. Dermatol. 121 (2003) 1500-1509
28. Kaushic C., Frauendorf E., Rossoll R.M., Richardson J.M., and Wira C.R. Influence of the estrous cycle on the presence and distribution of immune cells in the rat reproductive tract. Am. J. Reprod. Immunol. 39 (1998) 209-216
29. Khare S., Pater M.M., Tang S.C., and Pater A. Effect of glucocorticoid hormones on viral gene expression, growth, and dysplastic differentiation in HPV16-immortalized ectocervical cells. Exp. Cell Res. 232 (1997) 353-360
30. Komi J., Mottonen M., Luukkainen R., and Lassila O. Non-steroidal anti-oestrogens inhibit the differentiation of synovial macrophages into dendritic cells. Rheumatology (Oxford) 40 (2001) 185-191
31. Koyama Y., Nagao S., Ohashi K., Takahashi H., and Marunouchi T. Effect of systemic and topical application of testosterone propionate on the density of epidermal Langerhans cells in the mouse. J. Invest. Dermatol. 92 (1989) 86-90
32. Liehr J.G. Is estradiol a genotoxic mutagenic carcinogen?. Endocr. Rev. 21 (2000) 40-54
33. Liu H.Y., Buenafe A.C., Matejuk A., Ito A., Zamora A., Dwyer J., Vandenbark A.A., and Offner H. Estrogen inhibition of EAE involves effects on dendritic cell function. J. Neurosci. Res. 70 (2002) 238-248
34. Lubahn D.B., Moyer J.S., Golding T.S., Couse J.F., Korach K.S., and Smithies O. Alteration of reproductive function but not prenatal sexual development after insertional disruption of the mouse estrogen receptor gene. Proc. Natl. Acad. Sci. U.S.A. 90 (1993) 11162-11166
35. McMurray R.W., Ndebele K., Hardy K.J., and Jenkins J.K. 17-beta-estradiol suppresses IL-2 and IL-2 receptor. Cytokine 14 (2001) 324-333
36. Miller L., and Hunt J.S. Regulation of TNF-alpha production in activated mouse macrophages by progesterone. J. Immunol. 160 (1998) 5098-5104
37. Mohar A., and Frias-Mendivil M. Epidemiology of cervical cancer. Cancer Invest. 18 (2000) 584-590
38. Monsonego J., Magdelenat H., Catalan F., Coscas Y., Zerat L., and Sastre X. Estrogen and progesterone receptors in cervical human papillomavirus related lesions. Int. J. Cancer 48 (1991) 533-539
39. Moreno V., Bosch F.X., Munoz N., Meijer C.J., Shah K.V., Walboomers J.M., Herrero R., and Franceschi S. Effect of oral contraceptives on risk of cervical cancer in women with human papillomavirus infection: the IARC multicentric case-control study. Lancet 359 (2002) 1085-1092
40. Munoz N., Franceschi S., Bosetti C., Moreno V., Herrero R., Smith J.S., Shah K.V., Meijer C.J., and Bosch F.X. Role of parity and human papillomavirus in cervical cancer: the IARC multicentric case-control study. Lancet 359 (2002) 1093-1101
41. Nair H.B., Luthra R., Kirma N., Liu Y.G., Flowers L., Evans D., and Tekmal R.R. Induction of aromatase expression in cervical carcinomas: effects of endogenous estrogen on cervical cancer cell proliferation. Cancer Res. 65 (2005) 11164-11173
42. Newfield L., Bradlow H.L., Sepkovic D.W., and Auborn K. Estrogen metabolism and the malignant potential of human papillomavirus immortalized keratinocytes. Proc. Soc. Exp. Biol. Med. 217 (1998) 322-326
43. Pettersson A., Ciumas C., Chirsky V., Link H., Huang Y.M., and Xiao B.G. Dendritic cells exposed to estrogen in vitro exhibit therapeutic effects in ongoing experimental allergic encephalomyelitis. J. Neuroimmunol. 156 (2004) 58-65
44. Ravn V., Rasmussen B.B., Hojholt L., Barfoed M., Heiberg I., Svenstrup B., and Thorpe S.M. Estrogen- and progesterone receptors in normal cycling endometrium as studied by end-point titration. Cell Tissue Res. 276 (1994) 419-428
45. Remoue F., Jacobs N., Miot V., Boniver J., and Delvenne P. High intraepithelial expression of estrogen and progesterone receptors in the transformation zone of the uterine cervix. Am. J. Obstet. Gynecol. 189 (2003) 1660-1665
46. Robertson S.A., Mayrhofer G., and Seamark R.F. Ovarian steroid hormones regulate granulocyte-macrophage colony-stimulating factor synthesis by uterine epithelial cells in the mouse. Biol. Reprod. 54 (1996) 183-196
47. Rogers A., and Eastell R. The effect of 17beta-estradiol on production of cytokines in cultures of peripheral blood. Bone 29 (2001) 30-34
48. Romani N., Holzmann S., Tripp C.H., Koch F., and Stoitzner P. Langerhans cells-dendritic cells of the epidermis. APMIS 111 (2003) 725-740
49. Salazar E.L., Sojo-Aranda I., Lopez R., and Salcedo M. The evidence for an etiological relationship between oral contraceptive use and dysplastic change in cervical tissue. Gynecol. Endocrinol. 15 (2001) 23-28
50. Sanchez-Perez A.M., Soriano S., Clarke A.R., and Gaston K. Disruption of the human papillomavirus type 16 E2 gene protects cervical carcinoma cells from E2F-induced apoptosis. J. Gen. Virol. 78 Pt 11 (1997) 3009-3018
51. Schuurs A.H., and Verheul H.A. Effects of gender and sex steroids on the immune response. J. Steroid Biochem. 35 (1990) 157-172
52. Schwartz P.E. The oestrogen receptor (ER) in vulva, vagina and ovary. Eur. J. Cancer 36 Suppl. 4 (2000) S31-S32
53. Smedts F., Ramaekers F., Troyanovsky S., Pruszczynski M., Robben H., Lane B., Leigh I., Plantema F., and Vooijs P. Basal-cell keratins in cervical reserve cells and a comparison to their expression in cervical intraepithelial neoplasia. Am. J. Pathol. 140 (1992) 601-612
54. Tewari K.S., Taylor J.A., Liao S.Y., DiSaia P.J., Burger R.A., Monk B.J., Hughes C.C., and Villarreal L.P. Development and assessment of a general theory of cervical carcinogenesis utilizing a severe combined immunodeficiency murine-human xenograft model. Gynecol. Oncol. 77 (2000) 137-148
55. Tindle R.W. Immune evasion in human papillomavirus-associated cervical cancer. Nat. Rev. Cancer 2 (2002) 59-65
56. Vargas Roig L.M., Lotfi H., Olcese J.E., Lo C.G., and Ciocca D.R. Effects of short-term tamoxifen administration in patients with invasive cervical carcinoma. Anticancer Res. 13 (1993) 2457-2463
57. Webster K., Parish J., Pandya M., Stern P.L., Clarke A.R., and Gaston K. The human papillomavirus (HPV) 16 E2 protein induces apoptosis in the absence of other HPV proteins and via a p53-dependent pathway. J. Biol. Chem. 275 (2000) 87-94
58. Webster K., Taylor A., and Gaston K. Oestrogen and progesterone increase the levels of apoptosis induced by the human papillomavirus type 16 E2 and E7 proteins. J. Gen. Virol. 82 (2001) 201-213
59. Wieser F., Hosmann J., Tschugguel W., Czerwenka K., Sedivy R., and Huber J.C. Progesterone increases the number of Langerhans cells in human vaginal epithelium. Fertil. Steril. 75 (2001) 1234-1235
60. Wira C.R., and Rossoll R.M. Antigen-presenting cells in the female reproductive tract: influence of sex hormones on antigen presentation in the vagina. Immunology 84 (1995) 505-508
61. Wira C.R., Rossoll R.M., and Kaushic C. Antigen-presenting cells in the female reproductive tract: influence of estradiol on antigen presentation by vaginal cells. Endocrinology 141 (2000) 2877-2885
62. Witkiewicz A.K., Hecht J.L., Cviko A., McKeon F.D., Ince T.A., and Crum C.P. Microglandular hyperplasia: a model for the de novo emergence and evolution of endocervical reserve cells. Hum. Pathol. 36 (2005) 154-161
63. Young W.G., and Hosking A.R. Langerhans cells in murine vaginal epithelium affected by oestrogen and topical vitamin A. Acta Anat. (Basel) 125 (1986) 59-64
64. Yuan F., Auborn K., and James C. Altered growth and viral gene expression in human papillomavirus type 16-containing cancer cell lines treated with progesterone. Cancer Invest. 17 (1999) 19-29
65. Zhang Q.H., Hu Y.Z., Cao J., Zhong Y.Q., Zhao Y.F., and Mei Q.B. Estrogen influences the differentiation, maturation and function of dendritic cells in rats with experimental autoimmune encephalomyelitis. Acta Pharmacol. Sin. 25 (2004) 508-513
66. Zhu B.T., and Conney A.H. Functional role of estrogen metabolism in target cells: review and perspectives. Carcinogenesis 19 (1998) 1-27