Effect of glucocorticoid hormones on viral gene expression, growth, and dysplastic differentiation in HPV16-immortalized ectocervical cells

Experimental Cell Research

Volumn 232, Issue 2, 1997, Pages 353-360

  Khare, Suvarnalatha ^a   Pater, Mary M ^a   Tang, Shou Ching ^a   Pater, Alan ^a  

^a MEMORIAL UNIVERSITY OF NEWFOUNDLAND   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

GLUCOCORTICOID;

ARTICLE; CELL DIFFERENTIATION; CELL IMMORTALIZATION; FEMALE; HORMONE ACTION; HUMAN; HUMAN CELL; MALIGNANT TRANSFORMATION; PRIORITY JOURNAL; UTERINE CERVIX CANCER; UTERINE CERVIX DYSPLASIA; VIROGENESIS; VIRUS CARCINOGENESIS; VIRUS EXPRESSION; VIRUS GENE; WART VIRUS;

EID: 0031149440     PISSN: 00144827     EISSN: None     Source Type: Journal    
DOI: 10.1006/excr.1997.3529     Document Type: Article

References (50)

1. Bohkman, J. V., and Urmancheyeva, A. F. (1989) Cervix uteri cancer and pregnancy. Eur. J. Gynecol. Oncol. 10, 406-411.
2. Boyce, S. T., and Ham, R. G. (1985) Cultivation, frozen storage and clonal growth of normal human epidermal keratinocytes in serum-free media. J. Tissue Cult. Methods 9, 83-93.
3. Brinton, L. A. (1991) Oral contraceptives and cervical neoplasia. Contraception 43, 581-595.
4. Brinton, L. A., Herrero, R., Reeves, W. C., Gaitan, E., and Tenorio, F. (1993) Risk factors for cervical cancer by histology. Gynecol. Oncol. 51, 301-306.
5. Crook, T., Storey, A., Almond, N., Osborn, K, and Crawford, L. (1988) Human papillomavirus type 16 cooperates with activated ras and fos oncogenes in the hormone-dependent transformation of mouse cells. Proc. Natl. Acad. Sci. USA 85, 8820-8824.
6. Chan, W. K, Klock, G., and Bernard, H. U. (1989) Progesterone and glucocorticoid response elements occur in the long control regions of several human papillomaviruses involved in anogenital neoplasia. J. Virol. 63, 3261-3269.
7. Daniel, B., Mukherjee, G., Seshadri, L., Vallikad, E., and Krishna, S. (1995) Changes in physical state and expression of human papillomavirus type 16 in the progression of cervical intraepithelial neoplasia lesions analyzed by PCR. J. Gen. Virol. 76, 2589-2593.
8. Darbre, P. D., and King, R. J. B. (1987) Progression to steroid insensitivity can occur irrespective of the presence of functional steroid receptors. Cell 51, 521-528.
9. Denis, M. G., Chadeneau, C., Blanchardie, P., and Lustenberger, P. (1992) Biological effects of glucocorticoid hormones on two rat colon adenocarcinoma cell lines. J. Steroid Biochem. Mol. Biol. 41, 739-745.
10. Durst, M., Dzarlieva-Petrusevska, R., Boukamp, P., Fusenig, N., and Gissmann, L. (1987) Molecular and cytogenetic analysis of immortalized human primary keratinocytes obtained after transfection with human papillomavirus type 16 DNA. Oncogene 1, 251-256.
11. Durst, M., Gallahan, D., Jay, G., and Rhim, J. S. (1989) Glucocorticoid-enhanced neoplastic transformation of human keratinocytes by human papillomavirus type 16 and an activated ras oncogene. Virology 173, 767-771.
12. Durst, M., Bosch, F. X., Glitz, D., Schneider, A., and zur Hausen, H. (1991) Inverse relationship between human papillomavirus (HPV) type 16 early gene expression and cell differentiation in nude mouse epithelial cysts and tumors induced by HPV-positive human cell lines. J. Virol. 65, 796-804.
13. Felgner, P. L., Gadak, T. R., Holm, M., Roman, R., Chan, H. W., Wenz, M., Northrop, J. P., Ringold, G. M., and Danielsen, M. (1987) Lipofection: A highly efficient, lipid-mediated DNA transfection procedure. Proc. Natl. Acad. Sci. USA 84, 7413-17.
14. Ferenczy, A. (1989) HPV-associated lesions in pregnancy and their clinical implications. Clin. Obstet. Gynecol. 32, 191-199.
15. Gloss, B., Chong, T., and Bernard, H. U. (1989) Numerous nuclear proteins bind the long control region of human papillomavirus-16: a subset of 6 and 23 DNase I protected segments coincides with the location of the cell-type specific enhancer. J. Virol. 63, 1142-1152.
16. Gregoire, F., Genart, C., Hauser, N., and Remacle, C. (1991) Glucocorticoids induce a drastic inhibition of proliferation and stimulate differentiation of adult rat fat cell precursors. Exp. Cell Res. 196, 270-278.
17. Jee, S. H., Kuo, Y. F., Chen, Y., Cheung, S. H., Chiu, H. C., and Lee, S. C. (1993) Characterization of a human keratinocyte cell line immortalized by human papillomavirus 16 DNA. J. Formos. Med. Assoc. 92, 876-883.
18. Jeon, S., Allen-Hoffman, B. L., and Lambert, P. F. (1995) Integration of human papillomavirus type 16 into the human genome correlates with a selective growth advantage of cells. J. Virol. 69, 2989-2997.
19. Khare, S., Pater, M. M., and Pater, A. (1995) Role of exogenous cofactors in HPV infection and oncogenesis. Papillomavirus Rep. 6, 89-93.
20. Khare, S., Kumar, K. U., Tang, S-C., Pater, M. M., and Pater, A. (1996) Up-regulation of hormone response of human papillomavirus type 16 expression and increased DNA-protein binding by consensus mutations of viral glucocorticoid response elements. J. Med. Virol. 50, 254-262.
21. McCance, D. J., Kopan, R., Fuchs, E., and Laimins, L. A. (1988) Human papillomavirus type 16 alters human epithelial cell differentiation in vitro. Proc. Natl. Acad. Sci. USA 85, 7169-7173.
22. Meyers, C., Frattini, M. G., Hudson, J. B., and Laimins, L. A. (1992) Biosynthesis of human papillomavirus from a continuous cell line upon epithelial differentiation. Science 257, 971-973.
23. Mittal, T., Tsusumi, K, Pater, A., and Pater, M. M. (1993a) Human papillomavirus type 16 expression in cervical keratinocytes: Role of progesterone and glucocorticoid hormones. Obstet. Gynecol. 81, 5-12.
24. Mittal, R., Pater, A., and Pater, M. M. (1993b) Multiple human papillomavirus type 16 glucocorticoid response elements functional for transformation, transient expression and DNA-protein interactions. J. Virol. 67, 5656-5659.
25. Munger, K, Phelps, W., Bubb, V., Howley, P., and Schlegel, R. (1989) The E6 and E7 genes of the human papillomavirus type 16 together are necessary and sufficient of transformation of primary human keratinocytes. J. Virol. 63, 4417-4421.
26. Nakao, Y., Yang, X., Yokoyama, M., Pater, M. M., and Pater, A. (1996) Malignant transformation of human ectocervical cells immortalized by HPV 18: in vitro model of carcinogenesis by cigarette smoke. Carcinogenesis 17, 577-583.
27. Negrini, B. P., Schiffman, M. H., Kurman, R. J., Barnes, W., Launom, L., Malley, K., Brinton, L. A., Delgado, G., Jones, H., Tchabo, J. G., and Lancaster, W. D. (1990) Oral contraceptive use, human papillomavirus infection and risk of early cytological abnormalities of the cervix. Cancer Res. 50, 4070-4076.
28. Pater, M. M., Hughes, G. A., Hyslop, D. E., Nakshatri, H., and Pater, A. (1988) Glucocorticoid dependent oncogenic transformation by type 16 but not type 11 human papillomavirus DNA. Nature (London) 335, 832-835.
29. Pater, A., Bayatpour, M., and Pater, M. M. (1990) Oncogenic transformation by human papillomavirus type 16 deoxyribonucleic acid in the presence of progesterone or progestins from oral contraceptives. Am. J. Obstet. Gynaecol. 162, 1099-1103.
30. Pater, M. M., and Pater, A. (1991) RU486 inhibits glucocorticoid hormone-dependent oncogenesis by human papillomavirus type 16 DNA. Virology 183, 799-802.
31. Pater, A., Belaguli, N. S., and Pater, M. M. (1993) Glucocorticoid requirement for growth of human papillomavirus 16-transformed primary rat kidney epithelial cells: Correlation of development of hormone resistance with viral RNA expression and processing. Cancer Res. 53, 4432-4436.
32. Pim, D., Collins, M., and Banks, L. (1992) Human papillomavirus type 16 E5 gene stimulates the transforming activity of the epidermal growth factor receptor. Oncogene 7, 27-32.
33. Reagan, J. W., and Fu, Y. S. (1983) The uterine cervix. In Principles and Practice of Surgery Pathology (Silverberg, S. G., Ed.), p. 1223. Wiley, New York.
34. Rozansky, D., Wu, H., Tang, K, Parmer, R. J., and O'Conner, D. T. (1994) Glucocorticoid activation of chromogranin A gene expression. J. Clin. Invest. 94, 3257-3268.
35. Sambrook, J., Maniatis, T., and Fritsch, E. F. (1989) Molecular Cloning: A Laboratory Manual. Cold Spring Harbor Laboratory Press, New York.
36. Sarma, D., Yang, X., Jin, G., Shindoh, M., Pater, M. M., and Pater, A. (1996) Resistant to retinoic acid and altered cytokeratin expression of human papillomavirus type 16-immortalized endocervical cells after tumorigenesis. Int. J. Cancer 65: 345-350.
37. Shindoh, M., Sun, Q., Pater, A., and Pater, M. M. (1995) Prevention of carcinoma in situ of human papillomavirus type 16-immortalized human endocervical cells by retinoic acid in organotypic raft culture. Obstet. Gynecol. 85, 721-728.
38. Song, L. N., and Cheng, T. (1995) Glucocorticoid-induced growth inhibition and differentiation of a human megakaryoblastic leukemia cell line: Involvement of glucocorticoid receptor. Stem Cells Dayt. 11, 312-318.
39. Song, L. N. (1994) Effects of retinoic acid and dexamethasone on proliferation, differentiation and glucocorticoid receptor expression in cultured human osteosarcoma cells. Oncol. Res. 6, 111-118.
40. Stern, E., Forsythe, A., Yonkeles, L., and Coffelt, C. (1977) Steroid contraceptive use and cervical dysplasia: increased risk of progression. Science 236, 1666-1671.
41. Sun, Q., Tsutsumi, K, Kelleher, M. B., Pater, A., and Pater, M. M. (1992) Squamous metaplasia of normal and carcinoma in situ of HPV 16-immortalized human ectocervical cells. Cancer Res. 52, 4254-4260.
42. Tsutsumi, K., Belaguli, N., Qi, S., Michalak, T., Gulliver, W., Pater, A., and Pater, M. M. (1992) Human papillomavirus type 16 DNA immortalizes two types of normal epithelial cells of the uterine cervix. Am. J. Pathol. 140, 255-261.
43. Tsutsumi, K, Qi, S., Belaguli, N. S., Pater, M. M., and Pater, A. (1994) Distinct squamous phenotypes of Human cervical cell lines immortalized by human papillomavirus type 16. Mol. Cell. Diff. 2, 141-157.
44. Vooijs, G. P. (1991) Benign proliferative reactions, intraepithelial neoplasia and invasive cancer of the uterine cervix. In Comprehensive Cytopathology (Bibbo, M., Ed.), pp. 153-230. Saunders, Philadelphia.
45. von Knebel Doeberitz, M., Oltersdorf, T., Schwarz, E., and Gissmann, L. (1988) Correlation of modified human papillomavirus early gene expression with altered growth properties in C4-1 cervical carcinoma cells. Cancer Res. 48, 3780-3786.
46. von Knebel Doeberitz, M., Bauknecht, T., Bartsch, D., and Zur Hausen, H. (1991) Influence of chromosomal integration on glucocorticoid-regulated transcription of growth-stimulating papillomavirus genes E6 and E7 in cervical carcinoma cells. Proc. Natl. Acad. Sci. USA 88, 1411-1415.
47. Yang, X., Jin, G., Nakao, Y., Rahimtula, M., Pater, M. M., and Pater, A. (1996) Malignant transformation of HPV16-immortalized human endocervical cells by cigarette smoke condensate and characterization of multistep carcinogenesis. Int. J. Cancer 65: 338-344.
48. Yokoyama, M., Nakao, Y., Yang, X., Sun, Q., Tsutsumi, K., Pater, A., and Pater, M. M. (1995) Alterations in physical state and expression of human papillomavirus type 18 DNA following crisis and establishment of immortalized ectocervical cells. Virus Res. 37, 139-151.
49. Zheng, J., and Vaheri, A. (1995) Human skin fibroblasts induce anchorage-independent growth of HPV16 DNA immortalized cervical epithelial cells. Int. J. Cancer 61, 658-665.
50. zur Hausen, H., and de Villiers, E. M. (1994) Human Papillomaviruses. Annu. Rev. Microbiol. 48, 427-447.