Colonization of in vitro-formed cervical human papillomavirus- associated (pre)neoplastic lesions with dendritic cells: Role of granulocyte/macrophage colony-stimulating factor

American Journal of Pathology

Volumn 154, Issue 3, 1999, Pages 775-784

  Hubert, Pascale ^a,b   Van Den Brûle, Frederic ^a   Giannini, Sandra L ^a   Franzen Detrooz, Elizabeth ^a   Boniver, Jacques ^a   Delvenne, Philippe ^a  

^a UNIVERSITY OF LIÈGE   (Belgium)

^b CHU SART TILMAN   (Belgium)

Author keywords

[No Author keywords available]

Indexed keywords

COLONY STIMULATING FACTOR 1; GRANULOCYTE COLONY STIMULATING FACTOR; RECOMBINANT GRANULOCYTE MACROPHAGE COLONY STIMULATING FACTOR;

ARTICLE; CANCER IMMUNOTHERAPY; CELL INFILTRATION; CELL MIGRATION; CHEMOTAXIS; CONTROLLED STUDY; CULTURE MEDIUM; DENDRITIC CELL; ENZYME LINKED IMMUNOSORBENT ASSAY; FEMALE; HUMAN; HUMAN CELL; IMMUNOHISTOCHEMISTRY; KERATINOCYTE; LANGERHANS CELL; PHENOTYPE; PRECANCER; PRIORITY JOURNAL; UTERINE CERVIX EPITHELIUM; UTERINE CERVIX TUMOR;

EID: 0344507310     PISSN: 00029440     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0002-9440(10)65324-2     Document Type: Article

References (74)

1. Parkin D, Läärä E, Muir CS: Estimates of the worldwide frequency of sixteen major cancers in 1980. Int J Cancer 1988, 41:184-197
2. Bosch FX, Manos MM, Munoz N, Sherman M, Jansen AM, Peto J: Prevalence of human papillomavirus in cervical cancer: a worldwide perspective. International Biological Study on Cervical Cancer (IBSCC) Study Group. J Natl Cancer Inst 1995, 87:796-802
3. Cox MF, Meanwell CA, Maitland NJ, Blackledge G, Scully C, Jordan JA: Human papillomavirus type 16 homologous DNA in normal human ectocervix. Lancet 1986, ii:157-158
4. Toon PG, Arrand JR, Wilson LP, Sharp DS: Human papillomavirus infection of the uterine cervix of women without cytological signs of neoplasia. Br Med J 1986, 239:1261-1264
5. Al-Saleh W, Giannini SL, Jacobs N, Moutschen M, Doyen J, Boniver J, Delvenne P: Correlation of T helper secretory differentiation and types of antigen-presenting cells in squamous intraepithelial lesions of the uterine cervix. J Pathol 1998, 184:283-290
6. Thivolet J, Viac J, Staquet MJ: Cell mediated immunity in wart virus infection. Int J Dermatol 1982, 21:94-98
7. Wu TC: Immunology of the human papillomavirus in relation to cancer. Curr Opin Immunol 1994, 6:746-754
8. Hughes RG, Norval M, Howie SEM: Expression of major histocompatibility class II antigens by Langerhans' cells in cervical intraepithelial neoplasia. J Clin Pathol 1988, 41:253-259
9. Memar OM, Arany I, Tyring SK: Skin-associated lymphoid tissue in human immunodeficiency virus-1 human papillomavirus, and herpes simplex virus infections. J Invest Dermatol 1995, 105:99S-104S
10. Nickoloff JB, Turka LA: Immunological functions of non-professional antigen-presenting cells: new insights from studies of T-cell interactions with keratinocytes. Immunol Today 1994, 15:464-469
11. Coleman N, Birley HDL, Renton AM, Hanna NF, Ryait BK, Byrne M, Taylor-Robinson D, Stanley MA: Immunological events in regressing genital warts. Am J Clin Pathol 1994, 102:768-774
12. Morelli AE, Sananes C, Di Paola G, Paredes A, Fainboim L: Relationship between types of human papillomavirus and Langerhans' cells in cervical condyloma and intraepithelial neoplasia. Am J Clin Pathol 1993, 99:200-207
13. Sallusto F, Lanzavecchia A: Efficient presentation of soluble antigen by cultured human dendritic cells is maintained by granulocyte/ macrophage colony-stimulating factor plus interleukin 4 and down-regulated by tumor necrosis factor α. J Exp Med 1994, 179:1109-1118
14. Knight SC, Stagg AJ: Antigen-presenting cell types. Curr Opin Immunol 1993, 5:374-380
15. Tazi A, Bouchonnet F, Grandsaigne M, Boumsell L, Hance AJ, Soler P: Evidence that granulocyte macrophage-colony-stimulating factor regulates the distribution and differentiated state of dendritic cells/ Langerhans cells in human lung and lung cancers. J Clin Invest 1993, 91:566-576
16. Tsujitani S, Oka A, Kondo A, Ikeguchi M, Maeta M, Kaibara N: Infiltration of dendritic cells into regional lymph nodes in gastric cancer. Cancer 1995, 75:1478-1483
17. Nakano T, Oka K, Hanba K, Morita S: Intratumoral administration of Sizofiran activates Langerhans cell and T-cell infiltration in cervical cancer. Clin Immunol Immunopathol 1996, 79:79-86
18. Wu TC, Kurman RJ: Analysis of cytokine profiles in patients with human papillomavirus-associated neoplasms. J Natl Cancer Inst 1997, 87:185-187
19. Barker JNW, Mitra RS, Griffiths CEM, Dixit VM, Nickoloff BJ: Keratinocytes as initiators of inflammation. Lancet 1991, 337:211-214
20. Rosini S, Caltagirone S, Tallini G, Lattanzio G, Demopoulos R, Piantelli M, Musiani P: Depletion of stromal and intraepithelial antigen-presenting cells in cervical neoplasia in human immunodeficiency virus infection. Hum Pathol 1996, 27:834-839
21. Tang A, Amagai M, Granger LG, Stanley JR, Udey MC: Adhesion of epidermal Langerhans cells to keratinocytes mediated by E-cadherin. Nature 1993, 361:82-85
22. Vessey CJ, Wilding J, Folarin N, Hirano S, Takeichi M, Soutter P, Stamp GWH, Pigntelli M: Altered expression and function of E-cadherin in cervical intraepithelial neoplasia and invasive squamous cell carcinoma. J Pathol 1995, 176:151-159
23. Giannini SL, Al-Saleh W, Piron H, Jacobs N, Doyen J, Boniver J, Delvenne P: Cytokine expression in squamous intraepithelial lesions of the uterine cervix: implications for the generation of local immunosuppression. Clin Exp Immunol 1998, 113:183-189
24. Qin Z, Noffz G, Mohaupt M, Blankenstein T: Interleukin-10 prevents dendritic cell accumulation and vaccination with granulocyte-macrophage colony-stimulating factor gene-modified tumor cells. J Immunol 1997, 159:770-776
25. Katz S: The skin as an immunological organ: allergic contact dermatitis as a paradigm. J Dermatol 1993, 20:593-597
26. Woodworth CD, Simpson S: Comparative lymphokine secretion by cultured normal human cervical keratinocytes, papillomavirus-immortalized, and carcinoma cell lines. Am J Pathol 1993, 142:1544-1555
27. Kaplan G, Walsh G, Guido LS, Meyn P, Burkhardt RA, Abalos RM, Barker J, Frindt PA, Fajardo TT, Celona R, Cohn ZA: Novel responses of human skin to intradermal recombinant granulocyte/macrophage-colony-stimulating factor: Langerhans cell recruitment, keratinocyte growth and enhanced wound healing. J Exp Med 1992, 175:1717-1728
28. Pastore S, Fanales-Belasio E, Albanesi C, Chinni LM, Giannetti A, Girolomoni G: Granulocyte macrophage colony-stimulating factor is overproduced by keratinocytes in atopic dermatitis. J Clin Invest 1997, 99:3009-3017
29. Koch F, Heufler C, Kampgen E, Schneeweiss D, Bock G, Schuler G: Tumor necrosis factor α maintains the viability of murine epidermal Langerhans cells in culture, but in contrast to granulocyte/macrophage colony-stimulating factor, without inducing their functional maturation. J Exp Med 1990, 171:159-165
30. Tazi A, Bonay M, Bergeron A, Grandsaigne M, Hance AJ, Soler P: Role of granulocyte-macrophage colony stimulating factor (GM-CSF) in the pathogenesis of adult pulmonary histiocytosis X. Thorax 1996, 51:611-614
31. Stoppacciaro A, Paglia P, Lombardi L, Parmiani G, Baroni C, Colombo MP: Genetic modification of carcinoma with the IL-4 gene increase the influx of dendritic cells relative to other cytokines. Eur J Immunol 1997, 27:2375-2382
32. Delvenne P, Al-Saleh W, Gilles C, Thiry A, Boniver J: Inhibition of growth of normal and human papillomavirus-transformed keratinocytes in monolayer and organotypic cultures by interferon-γ and tumor necrosis factor-α. Am J Pathol 1995, 146:589-598
33. Aebischer F, McDougall JK: Organotypic raft cultures for the in vitro evaluation of vaginal microbicidal agents. Microbicides have epithelium-specific effects when repeatedly added onto organotypic human keratinocyte cultures. Sex Transm Dis 1997, 24:69-76
34. Eicher SA, Clayman GL, Liu TJ, Shillitoe EJ, Strothz KA, Roth JA, Lotan R: Evaluation of tropical gene therapy for head and neck squamous cell carcinoma in organotypic model. Clin Cancer Res 1996, 2:1659-1664
35. Shindoh M, Sun Q, Pater A, Pater MM: Prevention of carcinoma in situ of human papillomavirus type 16 immortalized human endocervical cells by retinoic acid in organotypic raft culture. Obstet Gynecol 1995, 85:721-728
36. Regnier M, Staquet MJ, Schmitt D, Schmidt R: Integration of Langerhans cells into a pigmented reconstructed human epidermis. J Invest Dermatol 1997, 109:510-512
37. Rader JS, Golub TR, Hudson JB, Patel D, Bedell MA, Laimins LA: In vitro differentiation of epithelial cells from cervical neoplasias resembles in vivo lesions. Oncogene 1990, 5:571-576
38. Blanton RA, Perez-Reyes N, Merrick DT, McDougall JK: Epithelial cells immortalized by human papillomaviruses have premalignant characteristics in organotypic cultures. Am J Pathol 1991, 138:673-685
39. Gilles C, Piette J, Rombouts S, Laurent C, Foidart JM: Immortalization of human cervical keratinocytes by human papillomavirus 33. Int J Cancer 1993, 53:872-879
40. Friedl F, Kimura I, Osato T, Ito Y: Studies on a new human cell line (SiHa) derived from carcinoma of uterus. I. Its establishment and morphology. Proc Soc Exp Biol Med 1970, 135:543-545
41. Pater M, Pater A: Human papillomavirus types 16 and 18 sequences in carcinoma cell lines of the cervix. Virology 1985, 145:313-318
42. Auersperg N, Hawryluk AF: Chromosome observations on three epithelial cell cultures derived from carcinomas of the uterine cervix. J Natl Cancer Inst 1962, 28:605-627
43. Hubert P, Greimers R, Franzen-Detrooz E, Doyen J, Delanaye P, Boniver J, Delvenne P: In vitro propagated dendritic cells from patients with human-papillomavirus-associated preneoplastic lesions of the uterine cervix: use of Flt3 ligand. Cancer Immunol Immunother 1998, 47:81-89
44. Merrick DT, Blanton RA, Gow AM, McDougall JK: Altered expression of proliferation and differentiation markers in human papillomavirus 16 and 18 immortalized epithelial cells grown in organotypic cultures. Am J Pathol 1992, 140:167-177
45. Castronovo V, Taraboletti G, Liotta LA, Sobel ME: Modulation of laminin receptor expression by estrogen and progestins in human breast cancer cell lines. J Natl Cancer Inst 1989, 81:781-788
46. Kobayashi Y, Staquet, MJ, Dezutter-Dambuyant C, Schmitt D: Development of motility of Langerhans cell through extra-cellular matrix by in vitro hapten contact. Eur J Immunol 1994, 24:2254-2257
47. Di Girolama w, Goni J, Laguens RP: Langerhans' cells in squamous metaplasia of the human uterine cervix. Gynecol Obstet Invest 1985, 19:38-43
48. Morelli A, Larregina A, Dipaola G, Fainboim L: Intraepithelial CD1 positive Langerhans cell precursor in transformation zone squamous metaplasia. Cervix 1991, 9:69-75
49. Al-Saleh W, Delvenne P, Arrese Estrada J, Nikkels AF, Piererd JE, Boniver J: Inverse modulation of intraepithelial Langerhans' cell and stromal macrophage/dendrocyte populations in human papillomavirus-associated squamous intraepithelial lesions of the cervix. Virchows Arch 1995, 427:41-49
50. Viac J, Guerin-Reverchon Y, Chardonnet Y, Bremond A: Langerhans cell and epidermal cell modifications in cervical intraepithelial neoplasia: correlation with human papillomavirus infection. Immunobiology 1990, 180:328-338
51. Smolle J, Soyer HP, Ehall R, Bartenstein S, Kerl H: Langerhans cell density in epithelial skin tumors correlates with epithelial differentiation but not with the peritumoral infiltrate. J Invest Dermatol 1986, 87:477-479
52. Rupec R, Magerstaedt R, Schirren CG, Sander E, Bieber T: Granulocyte/macrophage-colony-stimulating factor induces the migration of human epidermal Langerhans cells in vitro. Exp Dermatol 1996, 5:115-119
53. Markowicz S, Engleman E: Granulocyte-macrophage colony-stimulating factor promotes differentiation and survival of human peripheral blood dendritic cells in vitro. J Clin Invest 1990, 85:955-961
54. Witmer-Pack MD, Olivier W, Valinsky J, Schuler G, Steinman RM: Granulocyte/macrophage colony-stimulating factor is essential for the viability and function of cultured murine epidermal Langerhans cells. J Exp. Med 1987, 166:1484-1498
55. Xing Z, Braciak T, Ohkawara Y, Sallanave J-M, Foley R, Sime PJ, Jordana M, Graham FL Gauldie J: Gene transfer for cytokine functional studies in the lung: the multifunctional role of GM-CSF in pulmonary inflammation. J Leukoc Biol 1996, 59:481-488
56. Lappin MB, Kimber I, Norval M: The role of dendritic cells in cutaneous immunity. Arch Dermatol Res 1996, 288:109-121
57. Peters JH, Giesseler R, Thiele B, Steinbach F: Dendritic cells: from ontogenetic orphans to myelomonocytic descendants. Immunol Today 1996, 17:273-277
58. Rambukkana A, Bos JD, Irik D, Menko WJ, Kapsenberg ML, Das PK: In situ behavior of human Langerhans cells in skin organ culture. Lab Invest 1995, 73:521-531
59. Colasante A, Castrilli G, Bianca F, Brunetti M, Musiani P: Role of cytokines in distribution and differentiation of dendritic cell/ Langerhans'cell lineage in human primary carcinomas of the lung. Hum Pathol 1995, 26:866-872
60. Branunstein S, Kaplan G, Gottlieb AB, Schwartz M, Walsh G, Abalos RM, Fajardo TT, Guido LS, Krueger JG: GM-CSF activates regenerative epidermal growth and stimulates keratinocyte proliferation in human skin in vivo. J Invest Dermatol 1994, 103:601-604
61. Xing Z, Gauldie J, Tremblay GM, Hewlett BR, Addison C: Intradermal transgenic expression of granulocyte-macrophage colony stimulating factor induces neutrophilia, epidermal hyperplasia, Langerhans'cell/ macrophage accumulation, and dermal fibrosis. Lab Invest 1997, 77:615-622
62. Granelli-Piperno A, Moser B, Pope M, Chen D, Wei Y, Isdell F, O'Doherty U, Paxton W, Koup R, Mosjov S: Efficient interaction of HIV-1 with purified dendritic cells via multiple chemokine receptors. J Exp Med 1996, 184:2433-2438
63. Sozzani S, Sallusto F, Luni W, Zhou D, Piemonti L, Allavena P, Van Damme J, Valitutti S, Lanzavecchia A, Mantovani A: Migration of dendritic cells in response to formyl peptides, C5a and a distinct set of chemokines. J Immunol 1995, 155:3292-3295
64. Nakamura K, Williams IR, Kupper TS: Keratinocyte-derived monocyte chemoattractant protein 1 (MCP-1). Analysis in a transgenic model demonstrates MCP-1 can recruit dendritic and Langerhans cells to skin. J Invest Dermatol 1995, 105:635-643
65. Xu LL, Warren MK, Rose WL, Gong WH, Wang JM: Human recombinant monocyte chemotactic protein and other C-C chemokines bind and induce directional migration of dendritic cells in vitro. J Leukoc Biol 1996, 60:365-371
66. Greaves DR, Wang W, Dairaghi DJ, Dieu MC, de Saint-Vis B, Franz-Bacon K, Rossi D, Caux C, McClanahan T, Gordon S, Zlotnik A, Schall TJ: CCR6, a CC chemokine receptor that interacts with macrophage inflammatory protein 3α and is highly expressed in human dendritic cells. J Exp Med 1997, 186:837-844
67. Roake JA, Rao AS, Morris PJ, Larsen CP, Hankins DF, Austyn JM: Dendritic cell loss from nonlymphoid tissues after systemic administration of lipopolysaccharide, tumour necrosis factor and interleukin 1. J Exp Med 1995, 181:2237-2247
68. Cumberbatch M, Dearman RJ, Kimber I: Interleukin 1β and the stimulation of Langerhans cell migration: comparison with tumour necrosis factor α. Arch Dermatol Res 1997, 289:277-284
69. Cumberbatch M, Fielding I, Kimber I: Modulation of epidermal Langerhans' cell frequency by tumour necrosis factor-α. Immunology 1994, 81:395-401
70. Kradin RL, Xia W, Pike M, Byers HR, Pinto C: Interleukin-2 promotes the motility of dendritic cells and their accumulation in lung and skin. Pathobiology 1996, 64:180-186
71. Morelli A, Larregina A, Chuluyan E, Kolkowski A, Fainboim L: Expression and modulation of C5a receptor (CD88) on skin dendritic cells: chemotactic effect of C5a on skin migratory dendritic cells. Immunology 1996, 89:126-134
72. Udey MC: Cadherins and Langerhans cell immunobiology. Clin Exp Immunol 1997, 107:6-8
73. Price AA, Cumberbatch M, Kimber I, Ager A: α6 integrins are required for Langerhans cell migration from the epidermis. J Exp Med 1997, 186:1725-1735
74. Staquet MJ: Adhérence et migration des cellules dendritiques épidermiques. Pathol Biol 1995, 43:858-862