Oestrogen and progesterone increase the levels of apoptosis induced by the human papillomavirus type 16 E2 and E7 proteins

Journal of General Virology

Volumn 82, Issue 1, 2001, Pages 201-213

  Webster, K ^a   Taylor, A ^a   Gaston, K ^a  

^a UNIVERSITY OF BRISTOL   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

16ALPHA HYDROXYESTRONE; 3 INDOLEMETHANOL; ANTIGESTAGEN; DROLOXIFENE; ESTROGEN; ESTROGEN RECEPTOR; MIFEPRISTONE; PENICILLIN G; PROGESTERONE; STEROID; STREPTOMYCIN; VIRUS PROTEIN;

APOPTOSIS; ARTICLE; CELL DEATH; CONTROLLED STUDY; DISEASE COURSE; ESTROGEN METABOLISM; GENE EXPRESSION REGULATION; GENITAL SYSTEM; HORMONE ACTION; HUMAN; HUMAN CELL; NONHUMAN; PATHOGENESIS; PRIORITY JOURNAL; UTERINE CERVIX CANCER; VIRUS CELL TRANSFORMATION; VIRUS GENE; VIRUS INFECTION; VIRUS REPLICATION; WART VIRUS;

CANCER VIRUS; DNA VIRUSES; HUMAN PAPILLOMAVIRUS; HUMAN PAPILLOMAVIRUS TYPE 16; HUMAN PAPILLOMAVIRUS TYPES; PAPOVAVIRIDAE;

EID: 0035152250     PISSN: 00221317     EISSN: None     Source Type: Journal    
DOI: 10.1099/0022-1317-82-1-201     Document Type: Article

References (52)

1. Chronic estrogen-induced cervical and vaginal squamous carcinogenesis in human papillomavirus type 16 transgenic mice
2. The interaction between HPV infection and estrogen metabolism in cervical carcinogenesis
3. Transformation zone location and intraepithelial neoplasia of the cervix uteri
4. Structural and transcriptional analysis of human papillomavirus type 16 sequences in cervical carcinoma cell lines
5. Oestrogen increases S-phase fraction and oestrogen and progesterone receptors in human cervical cancer in vivo
6. Prevalence of human papillomavirus in cervical cancer: A worldwide perspective. International biological study on cervical cancer (IBSCC) Study Group
7. E7 protein of human papilloma virus-16 induces degradation of retinoblastoma protein through the ubiquitin-proteasome pathway
8. Risk factors for cervical intraepithelial neoplasia: Differences between low- and high-grade lesions
9. RU486 (Mifepristone): Mechanisms of action and clinical uses
10. Differential effects of progestins and estrogens on long control regions of human papilloma-virus types 16 and 18
11. The integration of HPV-18 DNA in cervical carcinoma
12. Indole-3-carbinol inhibits the expression of cyclin-dependent kinase-6 and induces a G1 cell cycle arrest of human breast cancer cells independent of estrogen receptor signaling
13. Expression of the papillomavirus E2 protein in HeLa cells leads to apoptosis
14. The physical state of human papillomavirus type 16 DNA in benign and malignant genital tumours
15. The human papilloma virus-16 E7 oncoprotein is able to bind to the retinoblastoma gene product
16. E2F-1 functions in mice to promote apoptosis and suppress proliferation
17. Repression of the integrated papillomavirus E6/E7 promoter is required for growth suppression of cervical cancer cells
18. Abrogation of a mitotic checkpoint by E2 proteins from oncogenic human papillomaviruses correlates with increased turnover of the p53 tumour suppressor protein
19. Biphasic regulation of breast cancer cell growth by progesterone: Role of the cyclin-dependent kinase inhibitors, p21 and p27Kip1
20. Human papillomavirus type 16 E6 increases the degradation rate of p53 in human keratinocytes
21. Hormonal regulation of the p53 tumor suppressor protein in T47D human breast carcinoma cell line
22. Destabilization of the RB tumor suppressor protein and stabilization of p53 contribute to HPV type 16 E7-induced apoptosis
23. RU486 increases radiosensitivity and restores apoptosis through modulation of HPV E6/E7 in dexamethasone-treated cervical carcinoma cells
24. Regulation of cell growth and HPV genes by exogenous estrogen in cervical cancer cells
25. Human papillomavirus E6 proteins bind p53 in vivo and abrogate p53-mediated repression of transcription
26. Interaction between the HPV-16 E2 transcriptional activator and p53
27. Regulation of human papillomavirus type 18 in vivo: Effects of estrogen and progesterone in transgenic mice
28. Induction of estradiol metabolism by dietary indole-3-carbinol in humans
29. Oestrogen stimulates differential transcription of human papillomavirus type 16 in SiHa cervical carcinoma cells
30. Human papillomavirus type 16 expression in cervical keratinocytes: Role of progesterone and glucocorticoid hormones
31. Rapid colorimetric assay for cellular growth and survival: Application to proliferation and cytotoxicity assays
32. Decreased programmed cell death in the uterine cervix associated with high risk human papillomavirus infection
33. Estrogen metabolism and the malignant potential of human papillomavirus immortalized keratinocytes
34. Oncogenic transformation by human papillomavirus type 16 deoxyribonucleic acid in the presence of progesterone or progestins from oral contraceptives
35. Deregulated transcription factor E2F-1 expression leads to S-phase entry and p53-mediated apoptosis
36. Increased frequency of detection of human papillomavirus deoxyribonucleic acid in exfoliated cervical cells during pregnancy
37. Disruption of the human papillomavirus type 16 E2 gene protects cervical carcinoma cells from E2F-induced apoptosis
38. The E6 oncoprotein encoded by human papillomavirus types 16 and 18 promotes the degradation of p53
39. Increased prevalence of human papillomaviruses in the lower genital tract of pregnant women
40. Integration of human papillomavirus type 16 DNA sequences: A possible early event in the progression of genital tumors
41. Human papillomavirus (HPV) type 18 E7 protein is a short-lived steroid-inducible phosphoprotein in HPV-transformed cell lines
42. Covalent binding of the endogenous estrogen 16 alpha-hydroxyestrone to estradiol receptor in human breast cancer cells: Characterization and intranuclear localization
43. Induction by estrogen metabolite 16 alpha-hydroxyestrone of genotoxic damage and aberrant proliferation in mouse mammary epithelial cells
44. HPV proteins in the control of HPV transcription
45. Human papillomaviruses: A neverending story?
46. Human papillomavirus is a necessary cause of invasive cervical cancer worldwide
47. The HPV 16 E2 protein induces apoptosis in the absence of other HPV proteins and via a p53-dependent pathway
48. Association of human papillomavirus types 16 and 18 E6 proteins with p53
49. p53 and E2F-1 cooperate to mediate apoptosis
50. Altered growth and viral gene expression in human papillomavirus type 16-containing cancer cell lines treated with progesterone
51. Anti-estrogenic activities of indole-3-carbinol in cervical cells: Implication for prevention of cervical cancer