Loss of IRA2 suppresses the growth defect on low glucose caused by the snf3 mutation in Saccharomyces cerevisiae

FEMS Yeast Research

Volumn 7, Issue 1, 2007, Pages 67-77

  Ramakrishnan, Vidhya ^a   Theodoris, George ^a,c   Bisson, Linda F ^a,b  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b Arcadia Bio Sciences ^*  (United States)

^c Arcadia Bio Sciences   (United States)

Author keywords

Genomic suppressor; Glucose sensing; HXT gene regulation; Low glucose growth; Oligonucleotide array

Indexed keywords

CYCLIC AMP; GLUCOSE TRANSPORTER; GUANOSINE TRIPHOSPHATASE ACTIVATING PROTEIN; REGULATOR PROTEIN; TRANSCRIPTION FACTOR SNF; TRANSCRIPTION FACTOR SNF 3; UNCLASSIFIED DRUG; YO L081W;

ALLELE; ARTICLE; CONTROLLED STUDY; FUNGAL GENE; FUNGUS GROWTH; GENE DELETION; GENE EXPRESSION; GENE ISOLATION; GENE MUTATION; GENE REPRESSION; GENETIC ANALYSIS; GENETIC REGULATION; GLYCOGEN METABOLISM; NONHUMAN; PHENOTYPE; SACCHAROMYCES CEREVISIAE; TRANSCRIPTOMICS; WILD TYPE;

GENE DELETION; GENE EXPRESSION REGULATION, FUNGAL; GLUCOSE; GTPASE-ACTIVATING PROTEINS; MONOSACCHARIDE TRANSPORT PROTEINS; MUTATION; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; SACCHAROMYCES CEREVISIAE; SACCHAROMYCES CEREVISIAE PROTEINS; TRANSCRIPTION, GENETIC;

SACCHAROMYCES CEREVISIAE;

EID: 33846270047     PISSN: 15671356     EISSN: 15671364     Source Type: Journal    
DOI: 10.1111/j.1567-1364.2006.00159.x     Document Type: Article

References (41)

1. Baudin A, Ozier-Kalogeropoulos O, Denouel A, Lacroute F & Bullin C (1993) A simple and efficient method for direct gene deletion in Saccharomyces cerevisiae. Nucleic Acids Res 21: 3329-3330.
2. Boles E, Zimmermann FK & Thevelein JM (1997) Metabolic signals. Yeast Sugar Metabolism: Biochemistry, Genetics and Applications (Zimmermann FK & Entian KD, eds), pp. 379-408. Technomic Publishing Company, Lancaster, PA.
3. Cannon JF, Pringle JR, Fiechter A & Khalil M (1994) Characterization of glycogen-deficient glc mutants of Saccharomyces cerevisiae. Genetics 136: 485-503.
4. Celenza JL & Carlson M (1984) Structure and expression of the snf-1 gene of Saccharomyces cerevisiae. Mol Cell Biol 4: 54-60.
5. Colombo S, Ronchetti D, Thevelein JM, Winderickx J & Martegani E (2004) Activation state of the Ras2 protein and glucose-induced signaling in Saccharomyces cerevisiae. J Biol Chem 279: 46715-46722.
6. Coons DM, Vagnoli P & Bisson LF (1997) The C-terminal domain of Snf3p is sufficient to complement the growth defect of snf3 null mutations in Saccharomyces cerevisiae: SNF3 functions in glucose recognition. Yeast 13: 9-20.
7. François J & Parrou JL (2001) Reserve carbohydrates metabolism in the yeast Saccharomyces cerevisiae. FEMS Microbiol Rev 25: 125-145.
8. François J, Balzquez MA, Arino J & Gancedo C (1997) Storage carbohydrates in the yeast Saccharomyces cerevisiae. Yeast Sugar Metabolism: Biochemistry, Genetics and Applications (Zimmermann FK & Entian KD, eds), pp. 285-312. Technomic Publishing Company, Lancaster, PA.
9. Guarente L (1983) Yeast promoters and lacZ fusions designed to study the expression of cloned genes in yeast. Methods Enzymol 101: 181-191.
10. Johnston M (1999) Feasting, fasting and fermenting: glucose sensing in yeast and other cells. Trends Genet 15: 29-33.
11. Kim J-H, Brachet V, Moriya H & Johnston M (2006) Integration of transcriptional and posttranscriptional regulation in a glucose signal transduction pathway in Saccharomyces cerevisiae. Eukaryot Cell 5: 167-173.
12. Ko CH, Liang H & Gaber RF (1993) Roles of multiple glucose transporters in Saccharomyces cerevisiae. Mol Cell Biol 13: 638-648.
13. Kruckeberg AL & Bisson LF (1990) The HXT2 gene of Saccharomyces cerevisiae is required for high-affinity glucose transport. Mol Cell Biol 10: 5903-5913.
14. Lewis DA & Bisson LF (1991) The HXT1 gene product of Saccharomyces cerevisiae is a new member of the family of hexose transporters. Mol Cell Biol 11: 3804-3813.
15. Li JJ & Herskowitz I (1993) Isolation of ORC6, a component of the yeast origin recognition complex, by a one-hybrid system. Science 262: 1870-1874.
16. Liang H & Gaber RF (1996) A novel signal transduction pathway in Saccharomyces cerevisiae defined by Snf3-regulated expression of HXT6. Mol Biol Cell 7: 1953-1966.
17. Luyten K, Riou C & Blondin B (2002) The hexose transporters of Saccharomyces cerevisiae play different roles during enological fermentation. Yeast 19: 713-726.
18. Marshall-Carlson L, Neigeborn L, Coons D, Bisson L & Carlson M (1991) Dominant and recessive suppressors that restore glucose transport in a yeast snf3 mutant. Genetics 128: 505-512.
19. Moriya H & Johnston M (2004) Glucose sensing and signaling in Saccharomyces cerevisiae through the Rgt2 glucose sensor and casein kinase I. Proc Natl Acad Sci USA 101: 1572-1577.
20. Mueller D, Exler S, Aguilera-Vazquez L, Guerrero-Martin E & Reuss M (2003) Cyclic AMP mediates the cell cycle dynamics of energy metabolism in Saccharomyces cerevisiae. Yeast 20: 351-367.
21. Nakafuku M, Obara T, Kaibuchi K, Miyajima I, Miyajima A, Itoh H, Nakamura S, Arai K-I, Matsumoto K & Kaziro Y (1988) Isolation of a second yeast Saccharomyces cerevisiae gene GPA2 coding for guanine nucleotide-binding regulatory protein: studies on its structure and possible functions. Proc Natl Acad Sci USA 85: 1374-1378.
22. Özcan S, Dover J, Rosenwald AG, Woelfl S & Johnston M (1996a) Two glucose transporters in Saccharomyces cerevisiae are glucose sensors that generate a signal for induction of gene expression. Proc Natl Acad Sci USA 93: 12428-12432.
23. Özcan S, Leong T & Johnston M (1996b) Rgt1p of Saccharomyces cerevisiae, a key regulator of glucose-induced genes, is both an activator and a repressor of transcription. Mol Cell Biol 16: 6419-6426.
24. Özcan S, Dover J & Johnston M (1998) Glucose sensing and signaling by two glucose receptors in the yeast Saccharomyces cerevisiae. EMBO J 17: 2566-2573.
25. Park J-I, Grant CM & Dawes IW (2005) The high-affinity cAMP phosphodiesterase of Saccharomyces cerevisiae is the major determinant of cAMP levels in stationary phase: involvement of different branches of the Ras-cyclic AMP pathway in stress responses. Biochem Biophys Res Commun 327: 311-319.
26. Rolland F, de Winde JH, Lemaire K, Boles E, Thevelein JM & Winderickx J (2000) Glucose-induced cAMP signaling in yeast requires both a G-protein coupled receptor system for extracellular glucose detection and a separable hexose kinase-dependent sensing process. Mol Microbiol 38: 348-358.
27. Rose MD, Winston F & Hieter P (1990) Methods in Yeast Genetics: A Laboratory Manual. Cold Spring Harbor Laboratory Press, Cold Spring Harbor, NY.
28. Schiestl RH, Manivasakam P, Woods RA & Gietz RD (1993) Introducing DNA into yeast by transformation. Methods 5: 79-85.
29. Schmidt MC, McCartney RR, Zhang X, Tillman TS, Solimeo H, Wolfl S, Almonte C & Watkins SC (1999) Std1 and Mth1 proteins interact with the glucose sensors to control glucose-regulated gene expression in Saccharomyces cerevisiae. Mol Cell Biol 19: 4561-4571.
30. Sherman F & Hicks J (1991) Micromanipulation and dissection of asci. Methods Enzymol 194: 21-37.
31. Sherman F, Fink GR & Hinks JB (1986) Methods in Yeast Genetics: A Laboratory Manual. Cold Spring Harbor Laboratory Press, Cold Spring Harbor, NY.
32. Tanaka K, Nakafuku M, Tamanoi F, Kaziro Y, Matsumoto K & Toh-E A (1990) IRA2, a second gene of Saccharomyces cerevisiae that encodes a protein with a domain homologous to mammalian Ras Gtpase-activating protein. Mol Cell Biol 10: 4303-4313.
33. Theodoris G & Bisson LF (2001) DDSE: downstream targets of the SNF3 signal transduction pathway. FEMS Microbiol Lett 197: 73-77.
34. Theodoris G, Fong NM, Coons DM & Bisson LF (1994) High-copy suppression of glucose transport defects by HXT4 and regulatory elements in the promoters of the HXT genes in Saccharomyces cerevisiae. Genetics 137: 957-966.
35. Thevelein JM (1994) Signal transduction in yeast. Yeast 10: 1753-1790.
36. Thevelein JM, Cauwenberg L, Colombo S et al. (2000) Nutrient-induced signal transduction through the protein kinase A pathway and its role in the control of metabolism, stress resistance, and growth in yeast. Enzyme Microbial Technol 26: 819-825.
37. Vagnoli P, Coons DM & Bisson LF (1998) The C-terminal domain of Snf3p mediates glucose-responsive signal transduction in Saccharomyces cerevisiae. FEMS Microbiol Lett 160: 31-36.
38. Wendell DL & Bisson LF (1993) Physiological characterization of putative high-affinity glucose transport protein Hxt2 of Saccharomyces cerevisiae by use of anti-synthetic peptide antibodies. J Bacteriol 175: 7689-7696.
39. Wendell DL & Bisson LF (1994) Expression of high-affinity glucose transport protein Hxt2p of Saccharomyces cerevisiae is both repressed and induced by glucose and appears to be regulated posttranslationally. J Bacteriol 176: 3730-3737.
40. Wilson RB, Renault G, Jacquet M & Tatchell K (1993) The pde2 gene of Saccharomyces cerevisiae is allelic to rca1 and encodes a phosphodiesterase which protects the cell from extracelllar cAMP. FEBS Lett 325: 191-195.
41. Wilson WA, Wang Z & Roach PJ (2002) Systematic identification of the genes affecting glycogen storage in the yeast Saccharomyces cerevisiae: implications of the vacuole as a determinant of glycogen level. Mol Cell Proteomics 1: 232-242.