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Volumn 16, Issue 11, 1996, Pages 6419-6426

Rgt1p of Saccharomyces cerevisiae, a key regulator of glucose-induced genes, is both an activator and a repressor of transcription

Author keywords

[No Author keywords available]

Indexed keywords

DNA BINDING PROTEIN; GLUCOSE; GLUCOSE TRANSPORTER; TRANSCRIPTION FACTOR; ZINC FINGER PROTEIN;

EID: 0029805138     PISSN: 02707306     EISSN: None     Source Type: Journal    
DOI: 10.1128/MCB.16.11.6419     Document Type: Article
Times cited : (136)

References (49)
  • 1
    • 0023392267 scopus 로고
    • A method for gene disruption that allows repeated use of URA3 selection in the construction of multiply disrupted yeast strains
    • Alani, E., L. Cao, and N. Kleckner. 1987. A method for gene disruption that allows repeated use of URA3 selection in the construction of multiply disrupted yeast strains. Genetics 116:541-545.
    • (1987) Genetics , vol.116 , pp. 541-545
    • Alani, E.1    Cao, L.2    Kleckner, N.3
  • 2
    • 0025128557 scopus 로고
    • The UGA3 gene regulating the GABA catabolic pathway in Saccharomyces cerevisiae codes for a putative zinc-finger protein acting on RNA amount
    • Andre, B. 1990. The UGA3 gene regulating the GABA catabolic pathway in Saccharomyces cerevisiae codes for a putative zinc-finger protein acting on RNA amount. Mol. Gen. Genet. 220:269-276.
    • (1990) Mol. Gen. Genet. , vol.220 , pp. 269-276
    • Andre, B.1
  • 3
    • 0027493475 scopus 로고
    • The Rox1 repressor of the Saccharomyces cerevisiae hypoxic genes is a specific DNA-binding protein with a high-mobility-group motif
    • Balasubramanian, B., C. V. Lowry, and R. S. Zitomer. 1993. The Rox1 repressor of the Saccharomyces cerevisiae hypoxic genes is a specific DNA-binding protein with a high-mobility-group motif. Mol. Cell. Biol. 13:6071-6078.
    • (1993) Mol. Cell. Biol. , vol.13 , pp. 6071-6078
    • Balasubramanian, B.1    Lowry, C.V.2    Zitomer, R.S.3
  • 6
    • 0023258701 scopus 로고
    • The SNF3 gene is required for high-affinity glucose transport in Saccharomyces cererisiae
    • Bisson, L. F., L. Neigeborn, M. Carlson, and D. G. Fraenkel. 1987. The SNF3 gene is required for high-affinity glucose transport in Saccharomyces cererisiae. J. Bacteriol. 169:1656-1662.
    • (1987) J. Bacteriol. , vol.169 , pp. 1656-1662
    • Bisson, L.F.1    Neigeborn, L.2    Carlson, M.3    Fraenkel, D.G.4
  • 7
    • 0029006193 scopus 로고
    • Positive control of yeast meiotic genes by the negative regulator UME6
    • Bowdish, K. S., H. E. Yuan, and A. P. Mitchell. 1995. Positive control of yeast meiotic genes by the negative regulator UME6. Mol. Cell. Biol. 15:2955-2961.
    • (1995) Mol. Cell. Biol. , vol.15 , pp. 2955-2961
    • Bowdish, K.S.1    Yuan, H.E.2    Mitchell, A.P.3
  • 8
    • 0022328481 scopus 로고
    • A eukaryotic transcriptional activator bearing the DNA specificity of a prokaryotic repressor
    • Brent, R., and M. Ptashne. 1985. A eukaryotic transcriptional activator bearing the DNA specificity of a prokaryotic repressor. Cell 43:729-736.
    • (1985) Cell , vol.43 , pp. 729-736
    • Brent, R.1    Ptashne, M.2
  • 9
    • 0024121499 scopus 로고
    • The yeast SNF3 gene encodes a glucose transporter homologous to the mammalian protein
    • Celenza, J. L., L. Marshall-Carlson, and M. Carlson. 1988. The yeast SNF3 gene encodes a glucose transporter homologous to the mammalian protein. Proc. Natl. Acad. Sci. USA 85:2130.
    • (1988) Proc. Natl. Acad. Sci. USA , vol.85 , pp. 2130
    • Celenza, J.L.1    Marshall-Carlson, L.2    Carlson, M.3
  • 10
    • 0029010746 scopus 로고
    • Computer-assisted nonlinear regression analysis of the multicomponent glucose uptake kinetics of Saccharomyces cerevisiae
    • Coons, D. M., R. B. Boulton, and L. F. Bisson. 1995. Computer-assisted nonlinear regression analysis of the multicomponent glucose uptake kinetics of Saccharomyces cerevisiae. J. Bacteriol. 177:3251-3258.
    • (1995) J. Bacteriol. , vol.177 , pp. 3251-3258
    • Coons, D.M.1    Boulton, R.B.2    Bisson, L.F.3
  • 11
    • 0028818262 scopus 로고
    • Mutational analysis of Rox1, a DNA-bending repressor of hypoxic genes in Saccharomyces cerevisiae
    • Deckert, J., A. M. Rodriguez Torres, J. T. Simon, and R. S. Zitomer. 1995. Mutational analysis of Rox1, a DNA-bending repressor of hypoxic genes in Saccharomyces cerevisiae. Mol. Cell. Biol. 15:6109-6117.
    • (1995) Mol. Cell. Biol. , vol.15 , pp. 6109-6117
    • Deckert, J.1    Rodriguez Torres, A.M.2    Simon, J.T.3    Zitomer, R.S.4
  • 12
    • 0026457028 scopus 로고
    • Regulation of sugar utilization by Saccharomyces cerevisiae
    • Entian, K.-D., and J. A. Barnett. 1992. Regulation of sugar utilization by Saccharomyces cerevisiae. Trends Biochem. Sci. 17:506-510.
    • (1992) Trends Biochem. Sci. , vol.17 , pp. 506-510
    • Entian, K.-D.1    Barnett, J.A.2
  • 13
    • 0028226607 scopus 로고
    • Suppressors reveal two classes of glucose repression genes in the yeast Saccharomyces cerevisiae
    • Erickson, J. R., and M. Johnston. 1994. Suppressors reveal two classes of glucose repression genes in the yeast Saccharomyces cerevisiae. Genetics 136:1271-1278.
    • (1994) Genetics , vol.136 , pp. 1271-1278
    • Erickson, J.R.1    Johnston, M.2
  • 14
    • 0025942492 scopus 로고
    • GRR1 of Saccharomyces cerevisiae is required for glucose repression and encodes a protein with leucine-rich repeats
    • Flick, J. S., and M. Johnston. 1991. GRR1 of Saccharomyces cerevisiae is required for glucose repression and encodes a protein with leucine-rich repeats. Mol. Cell. Biol. 11:5101-5112.
    • (1991) Mol. Cell. Biol. , vol.11 , pp. 5101-5112
    • Flick, J.S.1    Johnston, M.2
  • 15
    • 0026524634 scopus 로고
    • Carbon catabolite repression in yeast
    • Gancedo, J. M. 1992. Carbon catabolite repression in yeast. Eur. J. Biochem. 206:297-313.
    • (1992) Eur. J. Biochem. , vol.206 , pp. 297-313
    • Gancedo, J.M.1
  • 16
    • 0020645052 scopus 로고
    • Yeast promoters and lacZ fusions designed to study expression of cloned genes in yeast
    • Guarente, L. 1983. Yeast promoters and lacZ fusions designed to study expression of cloned genes in yeast. Methods Enzymol. 101:181-191.
    • (1983) Methods Enzymol. , vol.101 , pp. 181-191
    • Guarente, L.1
  • 17
    • 0022354870 scopus 로고
    • A repressor (MAT alpha 2 product) and its operator control expression of a set of cell type specific genes in yeast
    • Johnson, A. D., and I. Herskowitz. 1985. A repressor (MAT alpha 2 product) and its operator control expression of a set of cell type specific genes in yeast. Cell 42:237-247.
    • (1985) Cell , vol.42 , pp. 237-247
    • Johnson, A.D.1    Herskowitz, I.2
  • 18
    • 0023493883 scopus 로고
    • A model fungal gene regulatory mechanism: The GAL genes of Saccharomyces cerevisiae
    • Johnston, M. 1987. A model fungal gene regulatory mechanism: the GAL genes of Saccharomyces cerevisiae. Microbiol. Rev. 51:458-476.
    • (1987) Microbiol. Rev. , vol.51 , pp. 458-476
    • Johnston, M.1
  • 19
    • 0000632439 scopus 로고
    • Regulation of carbon and phosphate utilization
    • J. R. Broach, E. W. Jones, and J. Pringle (ed.), Cold Spring Harbor Laboratory Press, Cold Spring Harbor, N.Y.
    • Johnston, M., and M. Carlson. 1992. Regulation of carbon and phosphate utilization, p. 193-281. In J. R. Broach, E. W. Jones, and J. Pringle (ed.), The molecular and cellular biology of the yeast Saccharomyces, vol. 2. Cold Spring Harbor Laboratory Press, Cold Spring Harbor, N.Y.
    • (1992) The Molecular and Cellular Biology of the Yeast Saccharomyces , vol.2 , pp. 193-281
    • Johnston, M.1    Carlson, M.2
  • 20
    • 0026571899 scopus 로고
    • Ssn6-Tup1 is a general repressor of transcription in yeast
    • Keleher, C. A., M. J. Reed, J. Schultz, M. Carlson, and A. D. Johnson. 1992. Ssn6-Tup1 is a general repressor of transcription in yeast. Cell 68:709-719.
    • (1992) Cell , vol.68 , pp. 709-719
    • Keleher, C.A.1    Reed, M.J.2    Schultz, J.3    Carlson, M.4    Johnson, A.D.5
  • 21
    • 0027391981 scopus 로고
    • Roles of multiple glucose transporters in Saccharomyces cerevisiae
    • Ko, C. H., H. Liang, and R. F. Gaber. 1993. Roles of multiple glucose transporters in Saccharomyces cerevisiae. Mol. Cell. Biol. 13:638-648.
    • (1993) Mol. Cell. Biol. , vol.13 , pp. 638-648
    • Ko, C.H.1    Liang, H.2    Gaber, R.F.3
  • 22
    • 0028034201 scopus 로고
    • The WD repeats of Tup1 interact with the homeo domain protein alpha 2
    • Komachi, K., M. J. Redd, and A. D. Johnson. 1994. The WD repeats of Tup1 interact with the homeo domain protein alpha 2. Genes Dev. 8:2857-2867.
    • (1994) Genes Dev. , vol.8 , pp. 2857-2867
    • Komachi, K.1    Redd, M.J.2    Johnson, A.D.3
  • 23
    • 0023649184 scopus 로고
    • A new class of yeast transcriptional activators
    • Ma, J., and M. Ptashne. 1987. A new class of yeast transcriptional activators. Cell 51:113-119.
    • (1987) Cell , vol.51 , pp. 113-119
    • Ma, J.1    Ptashne, M.2
  • 24
    • 0025021668 scopus 로고
    • Mutational analysis of the SNF3 glucose transporter of Saccharomyces cervisiae
    • Marshall-Carlson, L., J. L. Celenza, B. C. Laurent, and M. Carlson. 1990. Mutational analysis of the SNF3 glucose transporter of Saccharomyces cervisiae. Mol. Cell. Biol. 10:1105-1115.
    • (1990) Mol. Cell. Biol. , vol.10 , pp. 1105-1115
    • Marshall-Carlson, L.1    Celenza, J.L.2    Laurent, B.C.3    Carlson, M.4
  • 25
    • 0025818026 scopus 로고
    • Dominant and recessive suppressors that restore glucose transport in a yeast snf3 mutant
    • Marshall-Carlson, L., L. Neigeborn, D. Coons, L. Bisson, and M. Carlson. 1991. Dominant and recessive suppressors that restore glucose transport in a yeast snf3 mutant. Genetics 128:505-512.
    • (1991) Genetics , vol.128 , pp. 505-512
    • Marshall-Carlson, L.1    Neigeborn, L.2    Coons, D.3    Bisson, L.4    Carlson, M.5
  • 26
    • 0023034916 scopus 로고
    • Yeast shuttle and integrative vectors with multiple cloning sites suitable for construction of lacZ fusions
    • Myers, A. M., A. Tzagoloff, D. M. Kinney, and C. J. Lusty. 1986. Yeast shuttle and integrative vectors with multiple cloning sites suitable for construction of lacZ fusions. Gene 45:299-310.
    • (1986) Gene , vol.45 , pp. 299-310
    • Myers, A.M.1    Tzagoloff, A.2    Kinney, D.M.3    Lusty, C.J.4
  • 27
    • 0029953712 scopus 로고    scopus 로고
    • Green fluorescent protein as a marker for gene expression and subcellular localization in budding yeast
    • Niedenthal, R. K., L. Riles, M. Johnston, and J. H. Hegemann. 1996. Green fluorescent protein as a marker for gene expression and subcellular localization in budding yeast. Yeast 12:773-786.
    • (1996) Yeast , vol.12 , pp. 773-786
    • Niedenthal, R.K.1    Riles, L.2    Johnston, M.3    Hegemann, J.H.4
  • 28
    • 0025901117 scopus 로고
    • Characterization of Hex2 protein, a negative regulatory element necessary for glucose repression in yeast
    • Niederacher, D., and K. D. Entian. 1991. Characterization of Hex2 protein, a negative regulatory element necessary for glucose repression in yeast. Eur. J. Biochem. 200:311-319.
    • (1991) Eur. J. Biochem. , vol.200 , pp. 311-319
    • Niederacher, D.1    Entian, K.D.2
  • 29
    • 85035181045 scopus 로고    scopus 로고
    • Two glucose transporters in S. cerevisiae are glucose sensors that generate a signal for induction of gene expression
    • in press
    • Özcan, S., J. Dover, A. G. Rosenwald, S. Wölfl, and M. Johnston. Two glucose transporters in S. cerevisiae are glucose sensors that generate a signal for induction of gene expression. Proc. Natl. Acad. Sci. USA, in press.
    • Proc. Natl. Acad. Sci. USA
    • Özcan, S.1    Dover, J.2    Rosenwald, A.G.3    Wölfl, S.4    Johnston, M.5
  • 30
    • 0027244246 scopus 로고
    • Glucose uptake and catabolite repression in dominant HTR1 mutants of Saccharomyces cerevisiae
    • Özcan, S., K. Freidel, A. Leuker, and M. Ciriacy. 1993. Glucose uptake and catabolite repression in dominant HTR1 mutants of Saccharomyces cerevisiae. J. Bacteriol. 175:5520-5528.
    • (1993) J. Bacteriol. , vol.175 , pp. 5520-5528
    • Özcan, S.1    Freidel, K.2    Leuker, A.3    Ciriacy, M.4
  • 31
    • 0028872732 scopus 로고
    • Three different regulatory mechanisms enable yeast hexose transporter (HXT) genes to be induced by different levels of glucose
    • Özcan, S., and M. Johnston. 1995. Three different regulatory mechanisms enable yeast hexose transporter (HXT) genes to be induced by different levels of glucose. Mol. Cell. Biol. 15:1564-1572.
    • (1995) Mol. Cell. Biol. , vol.15 , pp. 1564-1572
    • Özcan, S.1    Johnston, M.2
  • 32
    • 0029813252 scopus 로고    scopus 로고
    • Two different repressors collaborate to restrict expression of yeast glucose transporter genes HXT2 and HXT4 to low levels of glucose
    • Özcan, S., and M. Johnston. 1996. Two different repressors collaborate to restrict expression of yeast glucose transporter genes HXT2 and HXT4 to low levels of glucose. Mol. Cell. Biol. 16:5535-5545.
    • (1996) Mol. Cell. Biol. , vol.16 , pp. 5535-5545
    • Özcan, S.1    Johnston, M.2
  • 33
    • 0028105951 scopus 로고
    • Glucose uptake and metabolism in grr1/cat80 mutants of Saccharomyces cerevisiae
    • Özcan, S., F. Schulte, K. Freidel, A. Weber, and M. Ciriacy. 1994. Glucose uptake and metabolism in grr1/cat80 mutants of Saccharomyces cerevisiae. Eur. J. Biochem. 224:605-611.
    • (1994) Eur. J. Biochem. , vol.224 , pp. 605-611
    • Özcan, S.1    Schulte, F.2    Freidel, K.3    Weber, A.4    Ciriacy, M.5
  • 34
    • 0026497628 scopus 로고
    • The sequence of a 12 kb fragment on the left arm of yeast chromosome XI reveals five new open reading frames, including a zinc finger protein and a homolog of the UDP-glucose pyrophosphorylase from potato
    • Purnelle, B., J. Skala, L. V. Dyck, and A. Goffeau. 1992. The sequence of a 12 kb fragment on the left arm of yeast chromosome XI reveals five new open reading frames, including a zinc finger protein and a homolog of the UDP-glucose pyrophosphorylase from potato. Yeast 8:977-986.
    • (1992) Yeast , vol.8 , pp. 977-986
    • Purnelle, B.1    Skala, J.2    Dyck, L.V.3    Goffeau, A.4
  • 35
    • 0025772770 scopus 로고
    • Glucose repression in Saccharomyces cerevisiae is directly associated with hexose phosphorylation by hexokinases PI and PIII
    • Rose, M., W. Albig, and K.-D. Entian. 1991. Glucose repression in Saccharomyces cerevisiae is directly associated with hexose phosphorylation by hexokinases PI and PIII. Eur. J. Biochem. 199:511-518.
    • (1991) Eur. J. Biochem. , vol.199 , pp. 511-518
    • Rose, M.1    Albig, W.2    Entian, K.-D.3
  • 36
    • 0023545322 scopus 로고
    • A Saccharomyces cerevisiae genomic plasmid bank based on a centromere-containing shuttle vector
    • Rose, M. D., P. Novick, J. H. Thomas, D. Botstein, and G. R. Fink. 1987. A Saccharomyces cerevisiae genomic plasmid bank based on a centromere-containing shuttle vector. Gene 60:237-243.
    • (1987) Gene , vol.60 , pp. 237-243
    • Rose, M.D.1    Novick, P.2    Thomas, J.H.3    Botstein, D.4    Fink, G.R.5
  • 37
    • 0029990949 scopus 로고    scopus 로고
    • Induction of meiosis in Saccharomyces cerevisiae depends on conversion of the transcriptional repressor Ume6 to a positive regulator by its regulated association with the transcriptional activator Ime1
    • Rubin-Bejerano, I., S. Mandel, K. Robzyk, and Y. Kassir. 1996. Induction of meiosis in Saccharomyces cerevisiae depends on conversion of the transcriptional repressor Ume6 to a positive regulator by its regulated association with the transcriptional activator Ime1. Mol. Cell. Biol. 16:2518-2526.
    • (1996) Mol. Cell. Biol. , vol.16 , pp. 2518-2526
    • Rubin-Bejerano, I.1    Mandel, S.2    Robzyk, K.3    Kassir, Y.4
  • 38
    • 0023424198 scopus 로고
    • Molecular analysis of SSN6, a gene functionally related to the SNF1 protein kinase of Saccharomyces cerevisiae
    • Schultz, J., and M. Carlson. 1987. Molecular analysis of SSN6, a gene functionally related to the SNF1 protein kinase of Saccharomyces cerevisiae. Mol. Cell. Biol. 7:3637-3645.
    • (1987) Mol. Cell. Biol. , vol.7 , pp. 3637-3645
    • Schultz, J.1    Carlson, M.2
  • 40
    • 0028843868 scopus 로고
    • The tetratricopeptide repeats of Ssn6 interact with the homeo domain of alpha 2
    • Smith, R. L., M. J. Redd, and A. D. Johnson. 1995. The tetratricopeptide repeats of Ssn6 interact with the homeo domain of alpha 2. Genes Dev. 9:2903-2910.
    • (1995) Genes Dev. , vol.9 , pp. 2903-2910
    • Smith, R.L.1    Redd, M.J.2    Johnson, A.D.3
  • 42
    • 0028970369 scopus 로고
    • Repression by SSN6-TUP1 is directed by MIG1, a repressor/activator protein
    • Treitel, M. A., and M. Carlson. 1995. Repression by SSN6-TUP1 is directed by MIG1, a repressor/activator protein. Proc. Natl. Acad. Sci. USA 92:3132-3136.
    • (1995) Proc. Natl. Acad. Sci. USA , vol.92 , pp. 3132-3136
    • Treitel, M.A.1    Carlson, M.2
  • 43
    • 0026512705 scopus 로고
    • Glucose repression in the yeast Saccharomyces cerevisiae
    • Trumbly, R. J. 1992. Glucose repression in the yeast Saccharomyces cerevisiae. Mol. Microbiol. 6:15-21.
    • (1992) Mol. Microbiol. , vol.6 , pp. 15-21
    • Trumbly, R.J.1
  • 44
    • 0028340797 scopus 로고
    • Functional dissection of the yeast Cyc8-Tup1 transcriptional co-repressor complex
    • Tzamarias, D., and K. Struhl. 1994. Functional dissection of the yeast Cyc8-Tup1 transcriptional co-repressor complex. Nature (London) 369:758-761.
    • (1994) Nature (London) , vol.369 , pp. 758-761
    • Tzamarias, D.1    Struhl, K.2
  • 45
    • 0028969881 scopus 로고
    • Distinct TPR motifs of Cyc8 are involved in recruiting the Cyc8-Tup1 corepressor complex to differentially regulated promoters
    • Tzamarias, D., and K. Strahl. 1995. Distinct TPR motifs of Cyc8 are involved in recruiting the Cyc8-Tup1 corepressor complex to differentially regulated promoters. Genes Dev. 9:821-831.
    • (1995) Genes Dev. , vol.9 , pp. 821-831
    • Tzamarias, D.1    Strahl, K.2
  • 46
    • 0028316529 scopus 로고
    • Altered regulatory responses to glucose are associated with a glucose transport defect in grr1 mutants of Saccharomyces cerevisiae
    • Vallier, L. G., D. Coons, L. F. Bisson, and M. Carlson. 1994. Altered regulatory responses to glucose are associated with a glucose transport defect in grr1 mutants of Saccharomyces cerevisiae. Genetics 136:1279-1285.
    • (1994) Genetics , vol.136 , pp. 1279-1285
    • Vallier, L.G.1    Coons, D.2    Bisson, L.F.3    Carlson, M.4
  • 47
    • 0028244409 scopus 로고
    • Expression of high-affinity glucose transport protein Hxt2p of Saccharomyces cerevisiae is both repressed and induced by glucose and appears to be regulated posttranslationally
    • Wendell, D. L., and L. F. Bisson. 1994. Expression of high-affinity glucose transport protein Hxt2p of Saccharomyces cerevisiae is both repressed and induced by glucose and appears to be regulated posttranslationally. J. Bacteriol. 176:3730-3737.
    • (1994) J. Bacteriol. , vol.176 , pp. 3730-3737
    • Wendell, D.L.1    Bisson, L.F.2
  • 48
    • 0025804492 scopus 로고
    • The CYC8 and TUP1 proteins involved in glucose repression in Saccharomyces cerevisiae are associated in a protein complex
    • Williams, F. E., U. Varanasi, and R. J. Trumbly. 1991. The CYC8 and TUP1 proteins involved in glucose repression in Saccharomyces cerevisiae are associated in a protein complex. Mol. Cell. Biol. 11:3307-3316.
    • (1991) Mol. Cell. Biol. , vol.11 , pp. 3307-3316
    • Williams, F.E.1    Varanasi, U.2    Trumbly, R.J.3
  • 49
    • 0021710272 scopus 로고
    • Use of lacZ fusions to delimit regulatory elements of the inducible divergent GAL1-GAL10 promoter site in Saccharomyces cerevisiae
    • Yocum, R. R., S. Hanley, J. R. West, and M. Ptashne. 1984. Use of lacZ fusions to delimit regulatory elements of the inducible divergent GAL1-GAL10 promoter site in Saccharomyces cerevisiae. Mol. Cell. Biol. 4:1985-1998.
    • (1984) Mol. Cell. Biol. , vol.4 , pp. 1985-1998
    • Yocum, R.R.1    Hanley, S.2    West, J.R.3    Ptashne, M.4


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