Synthesis and characterization of semi-interpenetrating polymer network microspheres of acrylamide grafted dextran and chitosan for controlled release of acyclovir

Carbohydrate Polymers

Volumn 67, Issue 4, 2007, Pages 605-613

  Rokhade, Ajit P ^a   Patil, Sangamesh A ^a   Aminabhavi, Tejraj M ^a  

^a KARNATAK UNIVERSITY   (India)

Author keywords

Acyclovir; Crosslinking; Drug delivery systems; Graft copolymer; Hydrogels; Interpenetrating polymer networks; Microspheres

Indexed keywords

ALDEHYDES; CHITIN; COMPOSITION; CROSSLINKING; DIFFERENTIAL SCANNING CALORIMETRY; DIFFUSION; DRUG DOSAGE; EMULSIONS; GRAFT COPOLYMERS; POLYSACCHARIDES; SOLUBILITY; SWELLING; SYNTHESIS (CHEMICAL); ULTRAVIOLET SPECTROSCOPY; X RAY DIFFRACTION;

ACRYLAMIDE; ACYCLOVIR; CHITOSAN (CS); DEXTRAN; DIFFUSIONAL EXPONENT (N); DRUG DELIVERY SYSTEMS; MICROSPHERES;

INTERPENETRATING POLYMER NETWORKS;

EID: 33846244696     PISSN: 01448617     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.carbpol.2006.07.001     Document Type: Article

References (33)

1. Agnihotri S.A., and Aminabhavi T.M. Controlled release of clozapine through chitosan microparticles prepared by a novel method. Journal of Controlled Release 96 (2004) 245-259
2. Agnihotri S.A., and Aminabhavi T.M. Development of novel interpenetrating network gellan gum-poly (vinyl alcohol) hydrogel microspheres for the controlled release of carvedilol. Drug Development and Industrial Pharmacy 31 (2005) 491-503
3. Berger J., Reist M., Chenite A., Felt-Baeyens O., Mayer J.M., and Gurny R. Pseudo-thermosetting chitosan hydrogels for biomedical application. International Journal of Pharmaceutics 288 (2005) 197-206
4. Chen S.C., Wu Y.C., Mi F.L., Lin Y.H., Yu L.C., and Sung H.W. A novel pH-sensitive hydrogel composed of N,O-carboxymethyl chitosan and alginate cross-linked by genipin for protein drug delivery. Journal of Controlled Release 96 (2004) 285-300
5. Coviello T., Grassi M., Palleschi A., Bocchinfuso G., Coluzzi G., Banishoeib F., and Alhaique F. A new scleroglucan/borax hydrogel: swelling and drug release studies. International Journal of Pharmaceutics 289 (2005) 97-107
6. Franssen O., Vandervennet L., Roders P., and Hennink W.E. Degradable dextran hydrogels: Controlled release of a model protein from cylinders and microspheres. Journal of Controlled Release 60 (1999) 211-221
7. Garcia-Sellas J., Pascual A., Funes E., Pagan J.A., Lopez J.D., Negro J.M., and Hernandez J. Clinical efficacy and safety of a depigmented and glutaraldehyde polymerized therapeutic vaccine of parietaria judaica. Allergologia et Immunopathologia (Madrid) 31 (2003) 63-69
8. Harogoppad S.B., and Aminabhavi T.M. Diffusion and sorption of organic liquids through polymer membranes VIII. Elastomers versus monocyclic aromatic liquids. Journal of Applied Polymer Science 46 (1992) 725-732
9. Haynes P., Lambert T.R., and Mitchell I.D. Comparative in vivo genotoxicity of antiviral nucleoside analogues; penciclovir, acyclovir, ganciclovir and the xanthine analogue, caffeine in the mouse bone marrow micronucleus assay. Mutation Research 369 (1996) 65-74
10. Hejazi R., and Amiji M. Chitosan-based gastrointestinal delivery systems. Journal of Controlled Release 89 (2003) 151-165
11. Hennink W.E., De Jong S.J., Bos G.W., Veldhuis T.F.J., and van Nostrum C.F. Biodegradable dextran hydrogels crosslinked by stereocomplex formation for the controlled release of pharmaceutical proteins. International Journal of Pharmaceutics 277 (2004) 99-104
12. Hoffman A.S. Hydrogels for biomedical applications. Advanced Drug Delivery Reviews 43 (2002) 3-12
13. Hovgaard L., and Brondsted H. Dextran hydrogels for colon-specific drug delivery. Journal of Controlled Release 36 (1995) 159-166
14. Jakupec M.A., Unfried P., and Keppler B.K. Pharmacological properties of cerium compounds. Reviews of Physiology Biochemistry and Pharmacology 153 (2005) 101-111
15. Kim S.C., and Sperling L.H. IPNs around the world (1997), Wiley, New York
16. Korsmeyer R.C., and Peppas N.A. Effect of the morphology of hydrophilic polymeric matrices on the diffusion and release of water-soluble drugs. Journal of Membrane Science 9 (1981) 211-227
17. Kosmala J.D., Henthorn D.B., and Peppas L.B. Preparation of interpenetrating networks of gelatin and dextran as degradable biomaterials. Biomaterials 21 (2000) 2019-2023
18. Kumar M.N.V.R., Muzzarelli R.A.A., Muzzarelli C., Sashiwa H., and Domb A.J. Chitosan chemistry and pharmaceutical perspectives. Chemical Reviews 104 (2004) 6017-6084
19. Kurkuri M.D., and Aminabhavi T.M. Poly(vinyl alcohol) and poly(acrylic acid) sequential interpenetrating network pH sensitive microspheres for the delivery of diclofenac sodium to the intestine. Journal of Controlled Release 96 (2004) 9-20
20. Liu J., Lin S., Lin L., and Liu E. Release of theophylline from polymer blend hydrogels. International Journal of Pharmaceutics 298 (2005) 117-125
21. Lu Z., Steenekamp J.H., and Hamman J.H. Cross-linked cationic polymer microparticles: Effect of N-trimethyl chitosan chloride on the release and permeation of ibuprofen. Drug Development and Industrial Pharmacy 31 (2005) 311-317
22. Peppas N.A., Bures P., Leobandung W., and Ichikawa H. Hydrogels in pharmaceutical formulations. European Journal of Pharmaceutics and Biopharmaceutics 50 (2000) 27-46
23. Ritger P.L., and Peppas N.A. A simple equation for description of solute release. II Fickian and anomalous release from swellable devices. Journal of Controlled Release 5 (1987) 37-42
24. Robert C.C.R., Bun P.A., and Peppas N.A. Effect of degree of crosslinking on water transport in polymeric microparticles. Journal of Applied Polymer Science 30 (1985) 301-306
25. Rokhade A. P., Agnihotri S. A., Patil S. A., Mallikarjuna N. N., Kulkarni P. V., & Aminabhavi T. M. (in press). Semi-interpenetrating polymer network microspheres of gelatin and sodium carboxymethyl cellulose for controlled release of ketorolac tromethamine. Carbohydrate Polymers.
26. Rossi S., Sandri G., Ferrari F., Bonferoni M.C., and Caramella C. Development of films and matrices based on chitosan and polyacrylic acid for vaginal delivery of acyclovir. STP Pharm. Sci. 13 (2003) 183-190
27. Rossi S., Sandri G., Ferrari F., Bonferoni M.C., and Caramella C. Buccal delivery of acyclovir from films based on chitosan and polyacrylic acid. Pharmaceutical Development and Technology 8 (2003) 199-208
28. Sandri G., Rossi S., Ferrari F., Bonferoni M.C., Muzzarelli C., and Caramella C. Assessment of chitosan derivatives as buccal and vaginal penetration enhancers. European Journal of Pharmaceutical Sciences 21 (2004) 351-359
29. Soppimath K.S., and Aminabhavi T.M. Water transport and drug release study from crosslinked polyacrylamide-grafted-guargum hydrogel microspheres for the controlled release application. European Journal of Pharmaceutics and Biopharmaceutics 53 (2002) 87-98
30. Soppimath K.S., Kulkarni A.R., and Aminabhavi T.M. Controlled release of antihypertensive drug from the interpenetrating network poly(vinyl alcohol)-guar gum hydrogel microspheres. Journal of Biomaterial Science, Polymer Edition 11 (2000) 27-43
31. Stenekes R.J.H., and Hennink W.E. Equilibrium water content of microspheres based on cross-linked dextran. International Journal of Pharmaceutics 189 (1999) 131-135
32. Tu J., Wang L., Yang J., Fei H., and Li X. Formulation and pharmacokinetic studies of acyclovir controlled-release capsules. Drug Development and Industrial Pharmacy 27 (2001) 687-692
33. van Tomme S.R., van Steenbergen M.J., De Smedt S.C., van Nostrum C.F., and Hennink W.E. Self-gelling hydrogels based on oppositely charged dextran microspheres. Biomaterials 26 (2005) 2129-2135