Preparation of interpenetrating networks of gelatin and dextran as degradable biomaterials

Biomaterials

Volumn 21, Issue 20, 2000, Pages 2019-2023

  Kosmala, Jacqueline D ^a   Henthorn, David B ^a   Brannon Peppas, Lisa ^a  

^a Biogel Technology Inc   (United States)

Author keywords

Dextran; Gelatin; Glyceraldehyde; Hydrogels

Indexed keywords

ALDEHYDES; BIODEGRADATION; CHEBYSHEV APPROXIMATION; CROSSLINKING; HYDROGELS; INTERPENETRATING POLYMER NETWORKS; POLYSACCHARIDES; SWELLING;

DEXTRAN; GELATIN; GLYCERALDEHYDE;

IMPLANTS (SURGICAL);

BIOMATERIAL; DEXTRAN; GELATIN; POLYMER;

ARTICLE; BIODEGRADATION; CROSS LINKING; DISSOLUTION; DRUG SYNTHESIS; IN VITRO STUDY; PRIORITY JOURNAL; TECHNIQUE; TEMPERATURE;

BIOCOMPATIBLE MATERIALS; CALCIUM; DEXTRANS; GELATIN; GLYCERALDEHYDE;

EID: 0034308362     PISSN: 01429612     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0142-9612(00)00057-0     Document Type: Article

References (16)

1. Yamamoto N., Kurisawa M., Yui N. Double-stimuli-responsive degradable hydrogels. interpenetrating polymer networks consisting of gelatin and dextran with different phase separation Macromol Rapid Commun. 17:1996;313-318.
2. Kurisawa M, Yui N. Regulated drug release from double-stimuli-responsive degradable hydrogels: IPN-structured hydrogels of gelatin and dextran. Proceedings of International Symposium on Control Related Bioactive Materials, vol. 24, 1997. p. 579-80.
3. Silver FH, Garg AK. Collagen: characterization, processing and medical applications. In: Domb AJ, Kost J, Wiseman DM, editors. Handbook of biodegradable polymers. Amsterdam: Harwood Academic Publishers, 1997. p. 319-46.
4. Draye J.-P., Delaey B., Van de Voorde A., Van Den Bulcke A., Bogdanov B., Schacht E. In vitro release characteristics of bioactive molecules from dextran dialdehyde cross-linked gelatin hydrogel films. Biomaterials. 19:1998;99-107.
5. Cortesi R., Esposito E., Osti M., Squarzoni G., Menegatti E., Davis S.S., Nastruzzi C. Dextran cross-linked gelatin microsponges as a drug delivery system. Eur J Pharm Biopharm. 47:1999;153-160.
6. Tucker HA. Absorbable gelatin (gelfoam) sponge. Springfield, IL: Charles C. Thomas, 1965.
7. Lin F.-H., Yao C.-H., Sun J.-S., Liu H.-C., Haung C.-W. Biological effects and cytotoxicity of the composite composed by tricalcium phosphate and glutaraldehyde cross-linked gelatin. Biomaterials. 19:1998;905-917.
8. Segal A. The clinical use of dextran solutions. 1964;Grune and Stratter, New York.
9. de Raucort E., Mauray S., Chaubet F., Maiga-Revel O., Jozefowicz M., Fischer A.M. Anticoagulant activity of dextran derivatives. J Biomed Mater Res. 41:1998;49-57.
10. Tromp RH, Jones RAL. Off-critical phase separation and gelation in solutions of gelatin and dextran. Macromolecules 29:8109-16.
11. Vandelli M.A., Pifferri G., Seghizzi R., Cameroni R. Swelling behaviour of gelatin microspheres crosslinked with D,L-glyceraldehyde. The effect of the preparative factors. Pharm Pharmacol Lett. 3:1995;116-199.
12. Park K., Shalaby W., Park H. Biodegradable hydrogels for drug delivery. 1993;Technomic Publishing Co, Lancaster, PA.
13. Esposito E., Cortesi R., Nastruzzi C. Gleatin microspheres. influence of preparation parameters and thermal treatment on chemico-physical and biopharmaceutical properties Biomaterials. 17:1996;2009-2020.
14. Vandelli MA, Rivasi F, Guerra P, Scarpetta G, Arletti R, Forni F. A slow release dosage form for the subcutaneous drug administration. Proceedings of International Symposium on Control Related Bioactive Materials, vol. 24, 1997. p. 559-60.
15. Brønsted H., Andersen C., Hovgaard L. Crosslinked dextran - a new capsule material for colon targeting of drugs. J Control Rel. 53:1998;7-13.
16. Brannon-Peppas L., Peppas N.A. Dynamic and equilibrium swelling behaviour of pH-sensitive hydrogels containing 2-hydroxyethyl methacrylate. Biomaterials. 11:1990;635-644.