-
1
-
-
0037145025
-
The role of chaperone proteins in the aryl hydrocarbon receptor core complex
-
Petrulis, J. R.; Perdew, G. H. The role of chaperone proteins in the aryl hydrocarbon receptor core complex. Chem. Biol. Interact. 2002, 141, 25-40.
-
(2002)
Chem. Biol. Interact
, vol.141
, pp. 25-40
-
-
Petrulis, J.R.1
Perdew, G.H.2
-
2
-
-
0037212635
-
32P-labelled protein probes using a modified thioredoxin fusion protein expression system in Escherichia coli
-
32P-labelled protein probes using a modified thioredoxin fusion protein expression system in Escherichia coli. Biomol. Eng. 2003, 20, 1-5.
-
(2003)
Biomol. Eng
, vol.20
, pp. 1-5
-
-
Delucchi, A.B.1
Jensen, K.A.2
Chan, W.K.3
-
3
-
-
1342346637
-
-
2-regulated gene expression: transcriptional control of cardiorespiratory physiology by HIF-1. J. Appl. Physiol. 2004, 96, 1173-1177.
-
2-regulated gene expression: transcriptional control of cardiorespiratory physiology by HIF-1. J. Appl. Physiol. 2004, 96, 1173-1177.
-
-
-
-
4
-
-
0029103274
-
Hypoxia regulates vascular endothelial growth factor gene expression in endothelial cells. Identification of a 5′ enhancer
-
Liu, Y.; Cox, S. R.; Morita, T.; Kourembanas, S. Hypoxia regulates vascular endothelial growth factor gene expression in endothelial cells. Identification of a 5′ enhancer. Circ. Res. 1995, 77, 638-643.
-
(1995)
Circ. Res
, vol.77
, pp. 638-643
-
-
Liu, Y.1
Cox, S.R.2
Morita, T.3
Kourembanas, S.4
-
5
-
-
0029761644
-
Activation of vascular endothelial growth factor gene transcription by hypoxia-inducible factor 1
-
Forsythe, J. A.; Jiang, B. H.; Iyer, N. V.; Agani, F.; Leung, S. W.; Koos, R. D.; Semenza, G. L. Activation of vascular endothelial growth factor gene transcription by hypoxia-inducible factor 1. Mol. Cell. Biol. 1996, 16, 4604-4613.
-
(1996)
Mol. Cell. Biol
, vol.16
, pp. 4604-4613
-
-
Forsythe, J.A.1
Jiang, B.H.2
Iyer, N.V.3
Agani, F.4
Leung, S.W.5
Koos, R.D.6
Semenza, G.L.7
-
6
-
-
0032795850
-
Induction of the plasminogen activator inhibitor-1 gene expression by mild hypoxia via a hypoxia response element binding the hypoxia-inducible factor-1 in rat hepatocytes
-
Kietzmann, T.; Roth, U.; Jungermann, K. Induction of the plasminogen activator inhibitor-1 gene expression by mild hypoxia via a hypoxia response element binding the hypoxia-inducible factor-1 in rat hepatocytes. Blood 1999, 94, 4177-4185.
-
(1999)
Blood
, vol.94
, pp. 4177-4185
-
-
Kietzmann, T.1
Roth, U.2
Jungermann, K.3
-
7
-
-
0028068606
-
Transcriptional regulation of genes encoding glycolytic enzymes by hypoxia-inducible factor 1
-
Semenza, G. L.; Roth, P. H.; Fang, H. M.; Wang, G. L. Transcriptional regulation of genes encoding glycolytic enzymes by hypoxia-inducible factor 1. J. Biol. Chem. 1994, 269, 23757-23763.
-
(1994)
J. Biol. Chem
, vol.269
, pp. 23757-23763
-
-
Semenza, G.L.1
Roth, P.H.2
Fang, H.M.3
Wang, G.L.4
-
8
-
-
0029101515
-
Hypoxic regulation of lactate dehydrogenase A. Interaction between hypoxia-inducible factor 1 and cAMP response elements
-
Firth, J. D.; Ebert, B. L.; Ratcliffe, P. J. Hypoxic regulation of lactate dehydrogenase A. Interaction between hypoxia-inducible factor 1 and cAMP response elements. J. Biol. Chem. 1995, 270, 21021-21027.
-
(1995)
J. Biol. Chem
, vol.270
, pp. 21021-21027
-
-
Firth, J.D.1
Ebert, B.L.2
Ratcliffe, P.J.3
-
9
-
-
0030460724
-
Hypoxia response elements in the aldolase A, enolase 1, and lactate dehydrogenase A gene promoters contain essential binding sites for hypoxia-inducible factor 1
-
Semenza, G. L.; Jiang, B. H.; Leung, S. W.; Passantino, R.; Concordet, J. P.; Maire, P.; Giallongo, A. Hypoxia response elements in the aldolase A, enolase 1, and lactate dehydrogenase A gene promoters contain essential binding sites for hypoxia-inducible factor 1. J. Biol. Chem. 1996, 271, 32529-32537.
-
(1996)
J. Biol. Chem
, vol.271
, pp. 32529-32537
-
-
Semenza, G.L.1
Jiang, B.H.2
Leung, S.W.3
Passantino, R.4
Concordet, J.P.5
Maire, P.6
Giallongo, A.7
-
10
-
-
0032741858
-
Identification of an oxygen responsive enhancer element in the glyceraldehyde-3-phosphate dehydrogenase gene
-
Graven, K. K.; Yu, Q.; Pan, D.; Roncarati, J. S.; Farber, H. W. Identification of an oxygen responsive enhancer element in the glyceraldehyde-3-phosphate dehydrogenase gene. Biochim. Biophys. Acta 1999, 1447, 208-218.
-
(1999)
Biochim. Biophys. Acta
, vol.1447
, pp. 208-218
-
-
Graven, K.K.1
Yu, Q.2
Pan, D.3
Roncarati, J.S.4
Farber, H.W.5
-
11
-
-
7444259675
-
A randomized trial of letrozole in postmenopausal women after five years of tamoxifen therapy for early-stage breast cancer
-
Goss, P. E.; Ingle, J. N.; Martino, S.; Robert, N. J.; Muss, H. B.; Piccart, M. J.; Castiglione, M.; Tu, D.; Shepherd, L. E.; Pritchard, K. I.; Livingston, R. B.; Davidson, N. E.; Norton, L.; Perez, E. A.; Abrams, J. S.; Therasse, P.; Palmer, M. J.; Pater, J. L. A randomized trial of letrozole in postmenopausal women after five years of tamoxifen therapy for early-stage breast cancer. N. Engl. J. Med. 2003, 349, 1793-1802.
-
(2003)
N. Engl. J. Med
, vol.349
, pp. 1793-1802
-
-
Goss, P.E.1
Ingle, J.N.2
Martino, S.3
Robert, N.J.4
Muss, H.B.5
Piccart, M.J.6
Castiglione, M.7
Tu, D.8
Shepherd, L.E.9
Pritchard, K.I.10
Livingston, R.B.11
Davidson, N.E.12
Norton, L.13
Perez, E.A.14
Abrams, J.S.15
Therasse, P.16
Palmer, M.J.17
Pater, J.L.18
-
12
-
-
30544441340
-
Breast cancer, menopause, and long-term survivorship: Critical issues for the 21st century
-
Ganz, P. A. Breast cancer, menopause, and long-term survivorship: critical issues for the 21st century. Am. J. Med. 2005, 118, 136-141.
-
(2005)
Am. J. Med
, vol.118
, pp. 136-141
-
-
Ganz, P.A.1
-
13
-
-
0036216692
-
HIF-1 and tumor progression: Pathophysiology and therapeutics
-
Semenza, G. L. HIF-1 and tumor progression: pathophysiology and therapeutics. Trends Mol. Med. 2002, 8, 562-67.
-
(2002)
Trends Mol. Med
, vol.8
, pp. 562-567
-
-
Semenza, G.L.1
-
14
-
-
0036789574
-
Regulation of hypoxia-inducible factor 1alpha expression and function by the mammalian target of rapamycin
-
Hudson, C. C.; Liu, M.; Chiang, G. G.; Otterness, D. M.; Loomis, D. C.; Kaper, F.; Giaccia, A. J.; Abraham, R. T. Regulation of hypoxia-inducible factor 1alpha expression and function by the mammalian target of rapamycin. Mol. Cell. Biol. 2002, 22, 7004-7014.
-
(2002)
Mol. Cell. Biol
, vol.22
, pp. 7004-7014
-
-
Hudson, C.C.1
Liu, M.2
Chiang, G.G.3
Otterness, D.M.4
Loomis, D.C.5
Kaper, F.6
Giaccia, A.J.7
Abraham, R.T.8
-
15
-
-
0036219609
-
Hsp90 inhibitors as novel cancer chemotherapeutic agents
-
Neckers, L. Hsp90 inhibitors as novel cancer chemotherapeutic agents. Trends Mol. Med. 2002, 8, S55-S61.
-
(2002)
Trends Mol. Med
, vol.8
-
-
Neckers, L.1
-
16
-
-
0036569704
-
Geldanamycin induces degradation of hypoxia-inducible factor 1alpha protein via the proteosome pathway in prostate cancer cells
-
Mabjeesh, N. J.; Post, D. E.; Willard, M. T.; Kaur, B.; Van Meir, E. G.; Simons, J. W.; Zhong, H. Geldanamycin induces degradation of hypoxia-inducible factor 1alpha protein via the proteosome pathway in prostate cancer cells. Cancer Res. 2002 62, 2478-2482.
-
(2002)
Cancer Res
, vol.62
, pp. 2478-2482
-
-
Mabjeesh, N.J.1
Post, D.E.2
Willard, M.T.3
Kaur, B.4
Van Meir, E.G.5
Simons, J.W.6
Zhong, H.7
-
17
-
-
25444465116
-
Both microtubule-stabilizing and microtubule-destabilizing drugs inhibit hypoxia-inducible factor-1alpha accumulation and activity by disrupting microtubule function
-
Escuin, D.; Kline, E. R.; Giannakakou, P. Both microtubule-stabilizing and microtubule-destabilizing drugs inhibit hypoxia-inducible factor-1alpha accumulation and activity by disrupting microtubule function. Cancer Res. 2005, 65, 9021-9028.
-
(2005)
Cancer Res
, vol.65
, pp. 9021-9028
-
-
Escuin, D.1
Kline, E.R.2
Giannakakou, P.3
-
18
-
-
1242271198
-
Topoisomerase I-mediated inhibition of hypoxia-inducible factor 1: Mechanism and therapeutic implications
-
Rapisarda, A.; Uranchimeg, B.; Sordet, O.; Pommier, Y.; Shoemaker, R. H.; Melillo, G. Topoisomerase I-mediated inhibition of hypoxia-inducible factor 1: mechanism and therapeutic implications. Cancer Res. 2004, 64, 1475-1482.
-
(2004)
Cancer Res
, vol.64
, pp. 1475-1482
-
-
Rapisarda, A.1
Uranchimeg, B.2
Sordet, O.3
Pommier, Y.4
Shoemaker, R.H.5
Melillo, G.6
-
19
-
-
19944431335
-
Identification of a novel small-molecule inhibitor of the hypoxia-inducible factor 1 pathway
-
Tan, C.; de Noronha, R. G.; Roecker, A. J.; Pyrzynska, B.; Khwaja, F.; Zhang, Z.; Zhang, H.; Teng, Q.; Nicholson, A. C.; Giannakakou, P.; Zhou, W.; Olson, J. J.; Pereira, M. M.; Nicolaou, K. C.; Van Meir, E. G. Identification of a novel small-molecule inhibitor of the hypoxia-inducible factor 1 pathway. Cancer Res. 2005, 65, 605-612.
-
(2005)
Cancer Res
, vol.65
, pp. 605-612
-
-
Tan, C.1
de Noronha, R.G.2
Roecker, A.J.3
Pyrzynska, B.4
Khwaja, F.5
Zhang, Z.6
Zhang, H.7
Teng, Q.8
Nicholson, A.C.9
Giannakakou, P.10
Zhou, W.11
Olson, J.J.12
Pereira, M.M.13
Nicolaou, K.C.14
Van Meir, E.G.15
-
20
-
-
25444523184
-
-
Kong, D.; Park, E. J.; Stephen, A. G.; Calvani, M.; Cardellina, J. H.; Monks, A.; Fisher, R. J.; Shoemaker, R. H.; Melillo, G. Echinomycin, a small-molecule inhibitor of hypoxia-inducible factor-1 DNA-binding activity. Cancer Res. 2005, 65, 9047-9055.
-
Kong, D.; Park, E. J.; Stephen, A. G.; Calvani, M.; Cardellina, J. H.; Monks, A.; Fisher, R. J.; Shoemaker, R. H.; Melillo, G. Echinomycin, a small-molecule inhibitor of hypoxia-inducible factor-1 DNA-binding activity. Cancer Res. 2005, 65, 9047-9055.
-
-
-
-
21
-
-
0033405294
-
The hypoxic cell: A target for selective cancer therapy-eighteenth Bruce F. Cain Memorial Award lecture
-
Brown, J. M. The hypoxic cell: a target for selective cancer therapy-eighteenth Bruce F. Cain Memorial Award lecture. Cancer Res. 1999, 59, 5863-5870.
-
(1999)
Cancer Res
, vol.59
, pp. 5863-5870
-
-
Brown, J.M.1
-
22
-
-
33646353445
-
Mature results from a randomized Phase II trial of cisplatin plus 5-fluorouracil and radiotherapy with or without tirapazamine in patients with resectable Stage IV head and neck squamous cell carcinomas
-
Le, Q. T.; Taira, A.; Budenz, S.; Jo Dorie, M.; Goffinet, D. R.; Fee, W. E.; Goode, R.; Bloch, D.; Koong, A.; Martin Brown, J.; Pinto, H. A. Mature results from a randomized Phase II trial of cisplatin plus 5-fluorouracil and radiotherapy with or without tirapazamine in patients with resectable Stage IV head and neck squamous cell carcinomas. Cancer 2006, 106, 1940-1949.
-
(2006)
Cancer
, vol.106
, pp. 1940-1949
-
-
Le, Q.T.1
Taira, A.2
Budenz, S.3
Jo Dorie, M.4
Goffinet, D.R.5
Fee, W.E.6
Goode, R.7
Bloch, D.8
Koong, A.9
Martin Brown, J.10
Pinto, H.A.11
-
23
-
-
0038100188
-
Modulation of oestrogen receptor signalling by association with the activated dioxin receptor
-
Ohtake, F.; Takeyama, K.; Matsumoto, T.; Kitagawa, H.; Yamamoto, Y.; Nohara, K.; Tohyama, C.; Krust, A.; Mimura, J.; Chambon, P.; Yanagisawa, J.; Fujii-Kuriyama, Y.; Kato, S. Modulation of oestrogen receptor signalling by association with the activated dioxin receptor. Nature 2003, 423, 545-550.
-
(2003)
Nature
, vol.423
, pp. 545-550
-
-
Ohtake, F.1
Takeyama, K.2
Matsumoto, T.3
Kitagawa, H.4
Yamamoto, Y.5
Nohara, K.6
Tohyama, C.7
Krust, A.8
Mimura, J.9
Chambon, P.10
Yanagisawa, J.11
Fujii-Kuriyama, Y.12
Kato, S.13
-
24
-
-
0033958620
-
The aryl hydrocarbon receptor interacts with estrogen receptor alpha and orphan receptors COUP-TFI and ERRalpha1
-
Klinge, C. M.; Kaur, K.; Swanson, H. I. The aryl hydrocarbon receptor interacts with estrogen receptor alpha and orphan receptors COUP-TFI and ERRalpha1. Arch. Biochem. Biophys. 2000, 373, 163-174.
-
(2000)
Arch. Biochem. Biophys
, vol.373
, pp. 163-174
-
-
Klinge, C.M.1
Kaur, K.2
Swanson, H.I.3
-
25
-
-
20444381667
-
ERalpha-AHR-ARNT protein-protein interactions mediate estradiol-dependent transrepression of dioxin-inducible gene transcription
-
Beischlag, T. V.; Perdew, G. H. ERalpha-AHR-ARNT protein-protein interactions mediate estradiol-dependent transrepression of dioxin-inducible gene transcription. J. Biol. Chem. 2005, 280, 21607-21611.
-
(2005)
J. Biol. Chem
, vol.280
, pp. 21607-21611
-
-
Beischlag, T.V.1
Perdew, G.H.2
-
26
-
-
0035977882
-
Molecular biology of the Ah receptor and its role in carcinogenesis
-
Safe, S. Molecular biology of the Ah receptor and its role in carcinogenesis. Toxicol. Lett. 2001, 120, 1-7.
-
(2001)
Toxicol. Lett
, vol.120
, pp. 1-7
-
-
Safe, S.1
-
27
-
-
0030908818
-
Identification of a motif within the 5′ regulatory region of pS2 which is responsible for AP-1 binding and TCDD-mediated suppression
-
Gillesby, B. E.; Stanostefano, M.; Porter, W.; Safe, S.; Wu, Z. F.; Zacharewski, T. R. Identification of a motif within the 5′ regulatory region of pS2 which is responsible for AP-1 binding and TCDD-mediated suppression. Biochemistry 1997, 36, 6080-6089.
-
(1997)
Biochemistry
, vol.36
, pp. 6080-6089
-
-
Gillesby, B.E.1
Stanostefano, M.2
Porter, W.3
Safe, S.4
Wu, Z.F.5
Zacharewski, T.R.6
-
28
-
-
0032526627
-
Functional and physical interactions between the estrogen receptor Sp1 and nuclear aryl hydrocarbon receptor complexes
-
Wang, F.; Hoivik, D.; Pollenz, R.; Safe, S. Functional and physical interactions between the estrogen receptor Sp1 and nuclear aryl hydrocarbon receptor complexes. Nucleic Acids Res. 1998, 26, 3044-3052.
-
(1998)
Nucleic Acids Res
, vol.26
, pp. 3044-3052
-
-
Wang, F.1
Hoivik, D.2
Pollenz, R.3
Safe, S.4
-
29
-
-
0037637542
-
The basic helix-loop-helix-PAS protein ARNT functions as a potent coactivator of estrogen receptor-dependent transcription
-
Brunnberg, S.; Pettersson, K.; Rydin, E.; Matthews, J.; Hanberg, A.; Pongratz, I. The basic helix-loop-helix-PAS protein ARNT functions as a potent coactivator of estrogen receptor-dependent transcription. Proc. Natl. Acad. Sci. U.S.A. 2003, 100, 6517-6522.
-
(2003)
Proc. Natl. Acad. Sci. U.S.A
, vol.100
, pp. 6517-6522
-
-
Brunnberg, S.1
Pettersson, K.2
Rydin, E.3
Matthews, J.4
Hanberg, A.5
Pongratz, I.6
-
30
-
-
0035710746
-
Analysis of relative gene expression data using real-time quantitative PCR and the 2(-Delta Delta C(T)) Method
-
Livak, K. J.; Schmittgen, T. D. Analysis of relative gene expression data using real-time quantitative PCR and the 2(-Delta Delta C(T)) Method. Methods 2001, 25, 402-408.
-
(2001)
Methods
, vol.25
, pp. 402-408
-
-
Livak, K.J.1
Schmittgen, T.D.2
-
31
-
-
0034282518
-
Overexpression of hypoxia-inducible factor 1alpha is a marker for an unfavorable prognosis in early-stage invasive cervical cancer
-
Birner, P.; Schindl, M.; Obermair, A.; Plank, C.; Breitenecker, G.; Oberhuber, G. Overexpression of hypoxia-inducible factor 1alpha is a marker for an unfavorable prognosis in early-stage invasive cervical cancer. Cancer Res. 2000, 60, 4693-4696.
-
(2000)
Cancer Res
, vol.60
, pp. 4693-4696
-
-
Birner, P.1
Schindl, M.2
Obermair, A.3
Plank, C.4
Breitenecker, G.5
Oberhuber, G.6
-
32
-
-
0036278899
-
Overexpression of hypoxia-inducible factor 1alpha is associated with an unfavorable prognosis in lymph node-positive breast cancer
-
Schindl, M.; Schoppmann, S. F.; Samonigg, H.; Hausmaninger, H.; Kwasny, W.; Gnant, M.; Jakesz, R.; Kubista, E.; Birner, P.; Oberhuber, G. Overexpression of hypoxia-inducible factor 1alpha is associated with an unfavorable prognosis in lymph node-positive breast cancer. Clin. Cancer Res. 2002, 8, 1831-1837.
-
(2002)
Clin. Cancer Res
, vol.8
, pp. 1831-1837
-
-
Schindl, M.1
Schoppmann, S.F.2
Samonigg, H.3
Hausmaninger, H.4
Kwasny, W.5
Gnant, M.6
Jakesz, R.7
Kubista, E.8
Birner, P.9
Oberhuber, G.10
-
33
-
-
0033571682
-
Overexpression of hypoxia-inducible factor 1alpha in common human cancers and their metastases
-
Zhong, H.; De Marzo, A. M.; Laughner, E.; Lim, M.; Hilton, D. A.; Zagzag, D.; Buechler, P.; Isaacs, W. B.; Semenza, G. L.; Simons, J. W. Overexpression of hypoxia-inducible factor 1alpha in common human cancers and their metastases. Cancer Res. 1999, 59, 5830-5835.
-
(1999)
Cancer Res
, vol.59
, pp. 5830-5835
-
-
Zhong, H.1
De Marzo, A.M.2
Laughner, E.3
Lim, M.4
Hilton, D.A.5
Zagzag, D.6
Buechler, P.7
Isaacs, W.B.8
Semenza, G.L.9
Simons, J.W.10
-
34
-
-
4143110440
-
HIF-1: Master and commander of the hypoxic world. A pharmacological approach to its regulation by siRNAs
-
Mazure, N. M.; Brahimi-Horn, M. C.; Berta, M. A.; Benizri, E.; Bilton, R. L.; Dayan, F.; Ginouves, A.; Berra, E.; Pouyssegur, J. HIF-1: master and commander of the hypoxic world. A pharmacological approach to its regulation by siRNAs. Biochem. Pharmacol. 2004, 68, 971-980.
-
(2004)
Biochem. Pharmacol
, vol.68
, pp. 971-980
-
-
Mazure, N.M.1
Brahimi-Horn, M.C.2
Berta, M.A.3
Benizri, E.4
Bilton, R.L.5
Dayan, F.6
Ginouves, A.7
Berra, E.8
Pouyssegur, J.9
-
36
-
-
0031019835
-
Oxygen- and dioxin- regulated gene expression in mouse hepatoma cells
-
Gassmann, M.; Kvietikova, I.; Rolfs, A.; Wenger, R. H. Oxygen- and dioxin- regulated gene expression in mouse hepatoma cells. Kidney Int. 1997, 51, 567-574.
-
(1997)
Kidney Int
, vol.51
, pp. 567-574
-
-
Gassmann, M.1
Kvietikova, I.2
Rolfs, A.3
Wenger, R.H.4
-
37
-
-
0033597313
-
Cross-talk between the aryl hydrocarbon receptor and hypoxia inducible factor signaling pathways. Demonstration of competition and compensation
-
Chan, W. K.; Yao, G.; Gu, Y. Z.; Bradfield, C. A. Cross-talk between the aryl hydrocarbon receptor and hypoxia inducible factor signaling pathways. Demonstration of competition and compensation. J. Biol. Chem. 1999, 274, 12115-12123.
-
(1999)
J. Biol. Chem
, vol.274
, pp. 12115-12123
-
-
Chan, W.K.1
Yao, G.2
Gu, Y.Z.3
Bradfield, C.A.4
-
38
-
-
0032731702
-
Analysis of aryl hydrocarbon receptor-mediated signaling during physiological hypoxia reveals lack of competition for the aryl hydrocarbon nuclear translocator transcription factor
-
Pollenz, R. S.; Davarinos, N. A.; Shearer, T. P. Analysis of aryl hydrocarbon receptor-mediated signaling during physiological hypoxia reveals lack of competition for the aryl hydrocarbon nuclear translocator transcription factor. Mol. Pharmacol. 1999, 56, 1127-1137.
-
(1999)
Mol. Pharmacol
, vol.56
, pp. 1127-1137
-
-
Pollenz, R.S.1
Davarinos, N.A.2
Shearer, T.P.3
-
39
-
-
0034992644
-
Interactions between aryl hydrocarbon receptor (AhR) and hypoxia signaling pathways
-
Nie, M.; Blankenship, A. L.; Giesy, J. P. Interactions between aryl hydrocarbon receptor (AhR) and hypoxia signaling pathways. Environ. Toxicol. Pharmacol. 2001, 10, 17-27.
-
(2001)
Environ. Toxicol. Pharmacol
, vol.10
, pp. 17-27
-
-
Nie, M.1
Blankenship, A.L.2
Giesy, J.P.3
-
40
-
-
1542476903
-
-
Prasch, A. L.; Andreasen, E. A.; Peterson, R. E.; Heideman, W. Interactions between 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) and hypoxia signaling pathways in zebrafish: hypoxia decreases responses to TCDD in zebrafish embryos. Toxicol. Sci. 2004, 78, 68-77.
-
Prasch, A. L.; Andreasen, E. A.; Peterson, R. E.; Heideman, W. Interactions between 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) and hypoxia signaling pathways in zebrafish: hypoxia decreases responses to TCDD in zebrafish embryos. Toxicol. Sci. 2004, 78, 68-77.
-
-
-
-
41
-
-
0029888061
-
The role of the aryl hydrocarbon receptor nuclear translocator (ARNT) in hypoxic induction of gene expression. Studies in ARNT-deficient cells
-
Wood, S. M.; Gleadle, J. M.; Pugh, C. W.; Hankinson, O.; Ratcliffe, P. J. The role of the aryl hydrocarbon receptor nuclear translocator (ARNT) in hypoxic induction of gene expression. Studies in ARNT-deficient cells. J. Biol. Chem. 1996, 271, 15117-15123.
-
(1996)
J. Biol. Chem
, vol.271
, pp. 15117-15123
-
-
Wood, S.M.1
Gleadle, J.M.2
Pugh, C.W.3
Hankinson, O.4
Ratcliffe, P.J.5
-
42
-
-
0029655655
-
Dioxin-induced CYP1A1 transcription in vivo: The aromatic hydrocarbon receptor mediates transactivation, enhancer-promoter communication, and changes in chromatin structure
-
Ko, H. P.; Okino, S. T.; Ma, Q.; Whitlock, J. P., Jr. Dioxin-induced CYP1A1 transcription in vivo: the aromatic hydrocarbon receptor mediates transactivation, enhancer-promoter communication, and changes in chromatin structure. Mol. Cell. Biol. 1996, 16, 430-436.
-
(1996)
Mol. Cell. Biol
, vol.16
, pp. 430-436
-
-
Ko, H.P.1
Okino, S.T.2
Ma, Q.3
Whitlock Jr., J.P.4
-
43
-
-
0026377424
-
Inhibition of c-myc expression by phosphorothioate antisense oligonucleotide identifies a critical role for c-myc in the growth of human breast cancer
-
Watson, P. H.; Pon, R. T.; Shiu, R. P. Inhibition of c-myc expression by phosphorothioate antisense oligonucleotide identifies a critical role for c-myc in the growth of human breast cancer. Cancer Res. 1991, 51, 3996-4000.
-
(1991)
Cancer Res
, vol.51
, pp. 3996-4000
-
-
Watson, P.H.1
Pon, R.T.2
Shiu, R.P.3
-
44
-
-
21644489751
-
GREB 1 is a critical regulator of hormone dependent breast cancer growth
-
Rae, J. M.; Johnson, M. D.; Scheys, J. O.; Cordero, K. E.; Larios, J. M.; Lippman, M. E. GREB 1 is a critical regulator of hormone dependent breast cancer growth. Breast Cancer Res. Treat. 2005, 92, 141-149.
-
(2005)
Breast Cancer Res. Treat
, vol.92
, pp. 141-149
-
-
Rae, J.M.1
Johnson, M.D.2
Scheys, J.O.3
Cordero, K.E.4
Larios, J.M.5
Lippman, M.E.6
-
45
-
-
0037764668
-
Aryl hydrocarbon receptor gene silencing with small inhibitory RNA differentially modulates Ah- responsiveness in MCF-7 and HepG2 cancer cells
-
Abdelrahim, M.; Smith III, R.; Safe, S. Aryl hydrocarbon receptor gene silencing with small inhibitory RNA differentially modulates Ah- responsiveness in MCF-7 and HepG2 cancer cells. Mol. Pharmacol. 2003, 63, 1373-1381.
-
(2003)
Mol. Pharmacol
, vol.63
, pp. 1373-1381
-
-
Abdelrahim, M.1
Smith III, R.2
Safe, S.3
-
46
-
-
33746564251
-
Growth of a human mammary tumor cell line is blocked by galangin, a naturally occurring bioflavonoid, and is accompanied by down-regulation of cyclins D3, E, and A
-
Murray, T. J.; Yang, X.; Sherr, D. H. Growth of a human mammary tumor cell line is blocked by galangin, a naturally occurring bioflavonoid, and is accompanied by down-regulation of cyclins D3, E, and A. Breast Cancer Res. 2006, 8, R17.
-
(2006)
Breast Cancer Res
, vol.8
-
-
Murray, T.J.1
Yang, X.2
Sherr, D.H.3
-
47
-
-
31044444974
-
Reversing hypoxic cell chemoresistance in vitro using genetic and small molecule approaches targeting hypoxia inducible factor-1
-
Brown, L. M.; Cowen, R. L.; Debray, C.; Eustace, A.; Erler, J. T.; Sheppard, F. C.; Parker, C. A.; Stratford, I. J.; Williams, K. J. Reversing hypoxic cell chemoresistance in vitro using genetic and small molecule approaches targeting hypoxia inducible factor-1. Mol. Pharmacol. 2006, 69, 411-418.
-
(2006)
Mol. Pharmacol
, vol.69
, pp. 411-418
-
-
Brown, L.M.1
Cowen, R.L.2
Debray, C.3
Eustace, A.4
Erler, J.T.5
Sheppard, F.C.6
Parker, C.A.7
Stratford, I.J.8
Williams, K.J.9
-
48
-
-
0036531825
-
Antitumor effect of TAT-oxygen- dependent degradation-caspase-3 fusion protein specifically stabilized and activated in hypoxic tumor cells
-
Harada, H.; Hiraoka, M.; Kizaka-Kondoh, S. Antitumor effect of TAT-oxygen- dependent degradation-caspase-3 fusion protein specifically stabilized and activated in hypoxic tumor cells. Cancer Res. 2002, 62, 2013-2018.
-
(2002)
Cancer Res
, vol.62
, pp. 2013-2018
-
-
Harada, H.1
Hiraoka, M.2
Kizaka-Kondoh, S.3
-
49
-
-
33646678222
-
Antitumor protein therapy; application of the protein transduction domain to the development of a protein drug for cancer treatment
-
Harada, H.; Kizaka-Kondoh, S.; Hiraoka, M. Antitumor protein therapy; application of the protein transduction domain to the development of a protein drug for cancer treatment. Breast Cancer 2006, 13, 16-26.
-
(2006)
Breast Cancer
, vol.13
, pp. 16-26
-
-
Harada, H.1
Kizaka-Kondoh, S.2
Hiraoka, M.3
-
50
-
-
0037442965
-
Predominant suppression of apoptosome by inhibitor of apoptosis protein in non-small cell lung cancer H460 cells: Therapeutic effect of a novel polyarginine-conjugated Smac peptide
-
Yang, L.; Mashima, T.; Sato, S.; Mochizuki, M.; Sakamoto, H.; Yamori, T.; Oh-Hara, T.; Tsuruo, T. Predominant suppression of apoptosome by inhibitor of apoptosis protein in non-small cell lung cancer H460 cells: therapeutic effect of a novel polyarginine-conjugated Smac peptide. Cancer Res. 2003, 63, 831-837.
-
(2003)
Cancer Res
, vol.63
, pp. 831-837
-
-
Yang, L.1
Mashima, T.2
Sato, S.3
Mochizuki, M.4
Sakamoto, H.5
Yamori, T.6
Oh-Hara, T.7
Tsuruo, T.8
-
51
-
-
0035266403
-
The 104-123 amino acid sequence of the beta-domain of von Hippel-Lindau gene product is sufficient to inhibit renal tumor growth and invasion
-
Datta, K.; Sundberg, C.; Karumanchi, S. A.; Mukhopadhyay, D. The 104-123 amino acid sequence of the beta-domain of von Hippel-Lindau gene product is sufficient to inhibit renal tumor growth and invasion. Cancer Res. 2001, 61, 1768-1775.
-
(2001)
Cancer Res
, vol.61
, pp. 1768-1775
-
-
Datta, K.1
Sundberg, C.2
Karumanchi, S.A.3
Mukhopadhyay, D.4
-
52
-
-
0036822698
-
Transducible peptide therapy for uveal melanoma and retinoblastoma
-
Harbour, J. W.; Worley, L.; Ma, D.; Cohen, M. Transducible peptide therapy for uveal melanoma and retinoblastoma. Arch. Ophthalmol. 2002, 120, 1341-1346.
-
(2002)
Arch. Ophthalmol
, vol.120
, pp. 1341-1346
-
-
Harbour, J.W.1
Worley, L.2
Ma, D.3
Cohen, M.4
|