GREB1 is a critical regulator of hormone dependent breast cancer growth

Breast Cancer Research and Treatment

Volumn 92, Issue 2, 2005, Pages 141-149

  Rae, James M ^b   Johnson, Michael D ^a   Scheys, Joshua O ^b   Cordero, Kevin E ^b   Larios, José M ^b   Lippman, Marc E ^b  

^a GEORGETOWN UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b UNIVERSITY OF MICHIGAN MEDICAL SCHOOL   (United States)

Author keywords

Breast cancer; Estrogen induced growth; GREB1; Hormonal control

Indexed keywords

ESTRADIOL; ESTROGEN RECEPTOR ALPHA; FULVESTRANT; PROTEIN GREB 1; REGULATOR PROTEIN; SMALL INTERFERING RNA; STROMAL CELL DERIVED FACTOR 1; TAMOXIFEN; TREFOIL PEPTIDE; UNCLASSIFIED DRUG; GREB1 PROTEIN, HUMAN; TUMOR PROTEIN;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BREAST CARCINOGENESIS; BREAST CARCINOMA; CANCER CELL CULTURE; CANCER GROWTH; CANCER INHIBITION; CELL CYCLE S PHASE; CELL STRAIN MCF 7; CONTROLLED STUDY; DISEASE MARKER; DNA MICROARRAY; ESTROGEN ACTIVITY; GENE EXPRESSION PROFILING; GENE IDENTIFICATION; HORMONAL CARCINOGENESIS; HORMONE INHIBITION; HUMAN; HUMAN CELL; MITOSIS INHIBITION; MOUSE; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN INDUCTION; PROTEIN SYNTHESIS INHIBITION; PROTEIN TARGETING; REAL TIME POLYMERASE CHAIN REACTION; ANIMAL; BREAST TUMOR; EVALUATION; FEMALE; GENE EXPRESSION REGULATION; GENETICS; METABOLISM; NUDE MOUSE; RANDOMIZATION; RNA INTERFERENCE; TUMOR CELL LINE;

ANIMALS; BREAST NEOPLASMS; CELL LINE, TUMOR; ESTRADIOL; ESTROGEN RECEPTOR ALPHA; FEMALE; GENE EXPRESSION REGULATION, NEOPLASTIC; HUMANS; MICE; MICE, NUDE; NEOPLASM PROTEINS; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; RANDOM ALLOCATION; RNA INTERFERENCE;

EID: 21644489751     PISSN: 01676806     EISSN: None     Source Type: Journal    
DOI: 10.1007/s10549-005-1483-4     Document Type: Article

References (31)

1. American Cancer Society. Cancer Facts and Figures 2004, 2004.
2. RM Elledge SA Fuqua 2000 Estrogen and progesterone receptors J Harris ME Lippman M Morrow C Osborne Diseases of the Breast Lippincott, Williams and Wilkins Philadelphia 471 488
3. VC Jordan 2003 Tamoxifen: a most unlikely pioneering medicine Nat Rev Drug Discov 2 3 205 213
4. DP McDonnell JD Norris 2002 Connections and regulation of the human estrogen receptor Science 296 5573 1642 1644
5. MD Johnson H Zuo KH Lee JP Trebley JM Rae RV Weatherman Z Desta DA Flockhart TC Skaar 2004 Pharmacological characterization of 4-hydroxy-N- desmethyl tamoxifen, a novel active metabolite of tamoxifen Breast Cancer Res Treat 85 2 151 159
6. JM Rae ME Lippman 2004 Evaluation of novel epidermal growth factor receptor tyrosine kinase inhibitors Breast Cancer Res Treat 83 2 99 107
7. C Li WH Wong 2001 Model-based analysis of oligonucleotide arrays: expression index computation and outlier detection Proc Natl Acad Sci USA 98 1 31 36
8. AJ Bosma B Weigelt AC Lambrechts OJ Verhagen R Pruntel AA Hart S Rodenhuis VJ van't Veer 2002 Detection of circulating breast tumor cells by differential expression of marker genes Clin Cancer Res 8 6 1871 1877
9. J Laborda 1991 36B4 cDNA used as an estradiol-independent mRNA control is the cDNA for human acidic ribosomal phosphoprotein PO Nucleic Acids Res 19 14 3998
10. KJ Livak TD Schmittgen 2001 Analysis of relative gene expression data using real-time quantitative PCR and the 2(-Delta Delta C(T)) Method Methods 25 4 402 408
11. R Clarke N Brunner D Katz P Glanz RB Dickson ME Lippman FG Kern 1989 The effects of a constitutive expression of transforming growth factor-α on the growth of MCF-7 human breast cancer cells in vitro and in vivo Mol Endocrinol 3 2 372 380
12. P Workman A Balmain JA Hickman NJ McNally AM Rohas NA Mitchison CF Pierrepoint R Raymond C Rowlatt TC Stephens 1988 UKCCCR guidelines for the welfare of animals in experimental neoplasia Lab Anim 22 3 195 201
13. O Lefebvre MP Chenard R Masson J Linares A Dierich M LeMeur C Wendling C Tomasetto P Chambon MC Rio 1996 Gastric mucosa abnormalities and tumorigenesis in mice lacking the pS2 trefoil protein Science 274 5285 259 262
14. JM Hall KS Korach 2003 Stromal cell-derived factor 1, a novel target of estrogen receptor action, mediates the mitogenic effects of estradiol in ovarian and breast cancer cells Mol Endocrinol 17 5 792 803
15. MG Ghosh DA Thompson RJ Weigel 2000 PDZK1 and GREB1 are estrogen-regulated genes expressed in hormone-responsive breast cancer Cancer Res 60 22 6367 6375
16. M Lacroix G Leclercq 2004 Relevance of breast cancer cell lines as models for breast tumours: an update Breast Cancer Res Treat 83 3 249 289
17. M Soulez MG Parker 2001 Identification of novel oestrogen receptor target genes in human ZR75-1 breast cancer cells by expression profiling J Mol Endocrinol 27 3 259 274
18. A Inoue N Yoshida Y Omoto S Oguchi T Yamori R Kiyama S Hayashi 2002 Development of cDNA microarray for expression profiling of estrogen-responsive genes J Mol Endocrinol 29 2 175 192
19. J Frasor JM Danes B Komm KC Chang CR Lyttle BS Katzenellenbogen 2003 Profiling of estrogen up- and down-regulated gene expression in human breast cancer cells: insights into gene networks and pathways underlying estrogenic control of proliferation and cell phenotype Endocrinology 144 10 4562 4574
20. J Frasor F Stossi JM Danes B Komm CR Lyttle BS Katzenellenbogen 2004 Selective estrogen receptor modulators: discrimination of agonistic versus antagonistic activities by gene expression profiling in breast cancer cells Cancer Res 64 4 1522 1533
21. DY Wang R Fulthorpe SN Liss EA Edwards 2004 Identification of estrogen-responsive genes by complementary deoxyribonucleic acid microarray and characterization of a novel early estrogen-induced gene: EEIG1 Mol Endocrinol 18 2 402 411
22. Stossi F, Barnett DH, Frasor J, Komm B, Lyttle CR, Katzenellenbogen BS: Transcriptional profiling of estrogen-regulated gene expression via estrogen receptor α or estrogen receptor β in human osteosarcoma cells: distinct and common target genes for these receptors**. Endocrinology 2004
23. AM Brown JM Jeltsch M Roberts P Chambon 1984 Activation of pS2 gene transcription is a primary response to estrogen in the human breast cancer cell line MCF-7 Proc Natl Acad Sci USA 81 20 6344 6348
24. JA Foekens H Portengen MP Look WL van Putten B Thirion M Bontenbal JG Klijn 1994 Relationship of PS2 with response to tamoxifen therapy in patients with recurrent breast cancer Br J Cancer 70 6 1217 1223
25. JA Henry NH Piggott UK Mallick S Nicholson JR Farndon BR Westley 1991 pNR-2/pS2 immunohistochemical staining in breast cancer: correlation with prognostic factors and endocrine response Br J Cancer 63 4 615 622
26. E Oberlin A Amara F Bachelerie C Bessia JL Virelizier F Arenzana-Seisdedos O Schwartz JM Heard I Clark-Lewis DF Legler M Loetscher M Baggiolini B Moser 1996 The CXC chemokine SDF-1 is the ligand for LESTR/fusin and prevents infection by T-cell-line-adapted HIV-1 Nature 382 6594 833 835
27. A Muller B Homey H Soto N Ge D Catron ME Buchanan T McClanahan E Murphy W Yuan SN Wagner JL Barrera A Mohar E Verastegui A Zlotnik 2001 Involvement of chemokine receptors in breast cancer metastasis Nature 410 6824 50 56
28. T Nagase K Ishikawa N Miyajima A Tanaka H Kotani N Nomura O Ohara 1998 Prediction of the coding sequences of unidentified human genes. IX. The complete sequences of 100 new cDNA clones from brain which can code for large proteins in vitro DNA Res 5 1 31 39
29. M Peterfy J Phan GM Oswell P Xu K Reue 1999 Genetic, physical, and transcript map of the fld region on mouse chromosome 12 Genomics 62 3 436 444
30. CY Lin A Strom VB Vega SL Kong AL Yeo JS Thomsen WC Chan B Doray DK Bangarusamy A Ramasamy LA Vergara S Tang A Chong VB Bajic LD Miller JA Gustafsson ET Liu 2004 Discovery of estrogen receptor alpha target genes and response elements in breast tumor cells Genome Biol 5 9 R66
31. JT Chi HY Chang NN Wang DS Chang N Dunphy PO Brown 2003 Genomewide view of gene silencing by small interfering RNAs Proc Natl Acad Sci USA 100 11 6343 6346